AU614056B2 - Microbeads of diltiazem, a process for their manufacture and a sustained-release pharmaceutical composition containing them - Google Patents

Microbeads of diltiazem, a process for their manufacture and a sustained-release pharmaceutical composition containing them Download PDF

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Publication number
AU614056B2
AU614056B2 AU33363/89A AU3336389A AU614056B2 AU 614056 B2 AU614056 B2 AU 614056B2 AU 33363/89 A AU33363/89 A AU 33363/89A AU 3336389 A AU3336389 A AU 3336389A AU 614056 B2 AU614056 B2 AU 614056B2
Authority
AU
Australia
Prior art keywords
microbeads
diltiazem
membrane
microbeads according
core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU33363/89A
Other languages
English (en)
Other versions
AU3336389A (en
Inventor
Henri Desmolin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of AU3336389A publication Critical patent/AU3336389A/en
Application granted granted Critical
Publication of AU614056B2 publication Critical patent/AU614056B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU33363/89A 1988-04-27 1989-04-24 Microbeads of diltiazem, a process for their manufacture and a sustained-release pharmaceutical composition containing them Ceased AU614056B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8805629A FR2630647B1 (fr) 1988-04-27 1988-04-27 Microbilles de diltiazem, leur procede de fabrication et compositions pharmaceutiques a liberation prolongee les contenant
FR8805629 1988-04-27

Publications (2)

Publication Number Publication Date
AU3336389A AU3336389A (en) 1989-11-02
AU614056B2 true AU614056B2 (en) 1991-08-15

Family

ID=9365751

Family Applications (1)

Application Number Title Priority Date Filing Date
AU33363/89A Ceased AU614056B2 (en) 1988-04-27 1989-04-24 Microbeads of diltiazem, a process for their manufacture and a sustained-release pharmaceutical composition containing them

Country Status (12)

Country Link
EP (1) EP0340105B1 (enrdf_load_stackoverflow)
JP (1) JPH01313431A (enrdf_load_stackoverflow)
AT (1) ATE72974T1 (enrdf_load_stackoverflow)
AU (1) AU614056B2 (enrdf_load_stackoverflow)
CA (1) CA1336326C (enrdf_load_stackoverflow)
DE (1) DE68900903D1 (enrdf_load_stackoverflow)
ES (1) ES2032125T3 (enrdf_load_stackoverflow)
FR (1) FR2630647B1 (enrdf_load_stackoverflow)
GR (1) GR3003988T3 (enrdf_load_stackoverflow)
MX (1) MX9203020A (enrdf_load_stackoverflow)
NZ (1) NZ228846A (enrdf_load_stackoverflow)
ZA (1) ZA892871B (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288505A (en) * 1991-06-26 1994-02-22 Galephar P.R., Inc., Ltd. Extended release form of diltiazem
KR100221695B1 (ko) * 1991-08-12 1999-09-15 그린 마틴, 브라이언 쥐 테슬리 약학적 구상 제형
GB2258613B (en) * 1991-08-12 1996-01-10 Euro Celtique Sa Pharmaceutical diltiazem formulation
JPH08143450A (ja) * 1994-11-14 1996-06-04 Taiyo Yakuhin Kogyo Kk 徐放化製剤
FR2742660B1 (fr) * 1995-12-22 1998-04-03 Ethypharm Lab Prod Ethiques Nouvelles formes de microgranules a liberation prolongee contenant du diltiazem comme principe actif
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
ES2530450T3 (es) 2008-10-02 2015-03-03 Eyesense Ag Elemento sensor implantable

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4542042A (en) * 1982-07-16 1985-09-17 Tanabe Seiyaku Co., Ltd. Process for preparing free-flowing ethylcellulose microcapsules
US4721619A (en) * 1983-12-22 1988-01-26 Elan Corporation P.L.C. Controlled absorption diltiazen pharmaceutical formulation
US4859469A (en) * 1985-09-18 1989-08-22 Pharlyse Societe Anonyme Novel galenic forms of verapamil, their preparation and medicines containing said novel galenic forms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57120518A (en) * 1981-01-19 1982-07-27 Tanabe Seiyaku Co Ltd Preparation of microcapsule
JPS58116414A (ja) * 1981-12-23 1983-07-11 Yamanouchi Pharmaceut Co Ltd ニカルジピン持続性製剤用球形顆粒およびその製造法
LU85943A1 (fr) * 1985-06-12 1987-01-13 Galephar Comprimes pharmaceutiques permettant l'administration aisee de pellets, leur preparation et leur utilisation
JPS6232166A (ja) * 1985-08-06 1987-02-12 Mitsui Toatsu Chem Inc 発泡体加工用粘着剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4542042A (en) * 1982-07-16 1985-09-17 Tanabe Seiyaku Co., Ltd. Process for preparing free-flowing ethylcellulose microcapsules
US4721619A (en) * 1983-12-22 1988-01-26 Elan Corporation P.L.C. Controlled absorption diltiazen pharmaceutical formulation
US4859469A (en) * 1985-09-18 1989-08-22 Pharlyse Societe Anonyme Novel galenic forms of verapamil, their preparation and medicines containing said novel galenic forms

Also Published As

Publication number Publication date
AU3336389A (en) 1989-11-02
ZA892871B (en) 1990-12-28
MX9203020A (es) 1992-07-01
FR2630647A1 (fr) 1989-11-03
ATE72974T1 (de) 1992-03-15
FR2630647B1 (fr) 1991-08-16
GR3003988T3 (enrdf_load_stackoverflow) 1993-03-16
ES2032125T3 (es) 1993-01-01
CA1336326C (en) 1995-07-18
JPH01313431A (ja) 1989-12-18
DE68900903D1 (de) 1992-04-09
NZ228846A (en) 1991-06-25
EP0340105A1 (fr) 1989-11-02
EP0340105B1 (fr) 1992-03-04

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