AU517939B2 - N-(2-aminocyclopentyl) alkanoyl anilides - Google Patents

N-(2-aminocyclopentyl) alkanoyl anilides

Info

Publication number
AU517939B2
AU517939B2 AU36081/78A AU3608178A AU517939B2 AU 517939 B2 AU517939 B2 AU 517939B2 AU 36081/78 A AU36081/78 A AU 36081/78A AU 3608178 A AU3608178 A AU 3608178A AU 517939 B2 AU517939 B2 AU 517939B2
Authority
AU
Australia
Prior art keywords
aminocyclopentyl
anilides
alkanoyl
alkanoyl anilides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU36081/78A
Other languages
English (en)
Other versions
AU3608178A (en
Inventor
J Szmuszkovica
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/876,349 external-priority patent/US4204003A/en
Priority to US05/876,349 priority Critical patent/US4204003A/en
Priority to NL7803442A priority patent/NL7803442A/xx
Priority to DE19782817112 priority patent/DE2817112A1/de
Priority to JP5363178A priority patent/JPS54106451A/ja
Priority to AU36081/78A priority patent/AU517939B2/en
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to FR7815867A priority patent/FR2416882A2/fr
Priority to GB23590/78A priority patent/GB1581914A/en
Priority to BE188099A priority patent/BE867554R/xx
Publication of AU3608178A publication Critical patent/AU3608178A/en
Publication of AU517939B2 publication Critical patent/AU517939B2/en
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU36081/78A 1976-11-30 1978-05-12 N-(2-aminocyclopentyl) alkanoyl anilides Expired AU517939B2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
US05/876,349 US4204003A (en) 1976-11-30 1978-02-09 N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants
NL7803442A NL7803442A (nl) 1978-02-09 1978-03-31 Werkwijzen voor het bereiden en toepassen van amino-cycloalifatische amiden.
DE19782817112 DE2817112A1 (de) 1978-02-09 1978-04-19 N-(2-aminocyclopentyl)-n-alkanoylanilide oder deren 2-n-oxide, verfahren zu ihrer herstellung und verwendung derselben bei der behandlung depressiver zustaende
JP5363178A JPS54106451A (en) 1978-02-09 1978-05-04 Organic compound* its manufacture and medicine containing said compound
AU36081/78A AU517939B2 (en) 1978-02-09 1978-05-12 N-(2-aminocyclopentyl) alkanoyl anilides
FR7815867A FR2416882A2 (fr) 1978-02-09 1978-05-26 Composes d'alcanoylanilides et leur preparation
GB23590/78A GB1581914A (en) 1978-02-09 1978-05-26 N - (2-aminocyclopentyl) amides
BE188099A BE867554R (fr) 1978-02-09 1978-05-26 Composes alcanoylanilides et leur preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/876,349 US4204003A (en) 1976-11-30 1978-02-09 N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants
AU36081/78A AU517939B2 (en) 1978-02-09 1978-05-12 N-(2-aminocyclopentyl) alkanoyl anilides

Publications (2)

Publication Number Publication Date
AU3608178A AU3608178A (en) 1979-11-15
AU517939B2 true AU517939B2 (en) 1981-09-03

Family

ID=25623530

Family Applications (1)

Application Number Title Priority Date Filing Date
AU36081/78A Expired AU517939B2 (en) 1976-11-30 1978-05-12 N-(2-aminocyclopentyl) alkanoyl anilides

Country Status (7)

Country Link
JP (1) JPS54106451A (US06272168-20010807-M00014.png)
AU (1) AU517939B2 (US06272168-20010807-M00014.png)
BE (1) BE867554R (US06272168-20010807-M00014.png)
DE (1) DE2817112A1 (US06272168-20010807-M00014.png)
FR (1) FR2416882A2 (US06272168-20010807-M00014.png)
GB (1) GB1581914A (US06272168-20010807-M00014.png)
NL (1) NL7803442A (US06272168-20010807-M00014.png)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7902683A (nl) * 1978-04-10 1979-10-12 Upjohn Co Amino-cycloalifatische amiden.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines
DE2749214A1 (de) * 1976-11-30 1978-06-01 Upjohn Co N-(2-aminocyclopentyl)-n-alkanoylanilide oder deren 2-n-oxide, verfahren zu ihrer herstellung und verwendung derselben bei der behandlung depressiver zustaende

Also Published As

Publication number Publication date
DE2817112C2 (US06272168-20010807-M00014.png) 1988-01-07
FR2416882A2 (fr) 1979-09-07
JPS54106451A (en) 1979-08-21
GB1581914A (en) 1980-12-31
AU3608178A (en) 1979-11-15
BE867554R (fr) 1978-11-27
NL7803442A (nl) 1979-08-13
FR2416882B2 (US06272168-20010807-M00014.png) 1980-11-07
DE2817112A1 (de) 1979-08-16

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