AU508605B2 - 4, 5-Diaryl-2-Mercaptoimidazole derivatives and their use asanti-inflammatory and immunosuppressive agents - Google Patents

4, 5-Diaryl-2-Mercaptoimidazole derivatives and their use asanti-inflammatory and immunosuppressive agents

Info

Publication number
AU508605B2
AU508605B2 AU16711/76A AU1671176A AU508605B2 AU 508605 B2 AU508605 B2 AU 508605B2 AU 16711/76 A AU16711/76 A AU 16711/76A AU 1671176 A AU1671176 A AU 1671176A AU 508605 B2 AU508605 B2 AU 508605B2
Authority
AU
Australia
Prior art keywords
asanti
diaryl
inflammatory
immunosuppressive agents
mercaptoimidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU16711/76A
Other languages
English (en)
Other versions
AU1671176A (en
Inventor
S. C. & Sharpe T. R Cherkovski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of AU1671176A publication Critical patent/AU1671176A/en
Application granted granted Critical
Publication of AU508605B2 publication Critical patent/AU508605B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU16711/76A 1975-08-11 1976-08-10 4, 5-Diaryl-2-Mercaptoimidazole derivatives and their use asanti-inflammatory and immunosuppressive agents Expired AU508605B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60365075A 1975-08-11 1975-08-11
USUS603,650 1975-08-11
US69128276A 1976-06-09 1976-06-09
USUS691,282 1976-06-09

Publications (2)

Publication Number Publication Date
AU1671176A AU1671176A (en) 1978-02-16
AU508605B2 true AU508605B2 (en) 1980-03-27

Family

ID=27084480

Family Applications (1)

Application Number Title Priority Date Filing Date
AU16711/76A Expired AU508605B2 (en) 1975-08-11 1976-08-10 4, 5-Diaryl-2-Mercaptoimidazole derivatives and their use asanti-inflammatory and immunosuppressive agents

Country Status (26)

Country Link
JP (1) JPS6011702B2 (enrdf_load_stackoverflow)
AR (2) AR215591A1 (enrdf_load_stackoverflow)
AU (1) AU508605B2 (enrdf_load_stackoverflow)
CA (1) CA1074327A (enrdf_load_stackoverflow)
CH (1) CH638791A5 (enrdf_load_stackoverflow)
DD (1) DD126244A5 (enrdf_load_stackoverflow)
DE (1) DE2635876A1 (enrdf_load_stackoverflow)
DK (1) DK361376A (enrdf_load_stackoverflow)
ES (2) ES450601A1 (enrdf_load_stackoverflow)
FI (1) FI66177C (enrdf_load_stackoverflow)
FR (1) FR2320745A1 (enrdf_load_stackoverflow)
GB (1) GB1516908A (enrdf_load_stackoverflow)
GR (1) GR61145B (enrdf_load_stackoverflow)
HU (1) HU174707B (enrdf_load_stackoverflow)
IE (1) IE44019B1 (enrdf_load_stackoverflow)
IL (1) IL50230A (enrdf_load_stackoverflow)
LU (1) LU75578A1 (enrdf_load_stackoverflow)
MX (1) MX3932E (enrdf_load_stackoverflow)
NL (1) NL7608915A (enrdf_load_stackoverflow)
NO (1) NO146571C (enrdf_load_stackoverflow)
NZ (1) NZ181731A (enrdf_load_stackoverflow)
PH (1) PH11857A (enrdf_load_stackoverflow)
PT (1) PT65464B (enrdf_load_stackoverflow)
SE (1) SE428686B (enrdf_load_stackoverflow)
SU (1) SU640662A3 (enrdf_load_stackoverflow)
YU (1) YU198176A (enrdf_load_stackoverflow)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK16778A (da) * 1977-02-09 1978-08-10 Du Pont Imidazolderivater deres anvendelser og fremstilling
LU77703A1 (de) * 1977-07-07 1979-03-26 Ciba Geigy Ag Verfahren zur herstellung von bicyclischen thia-diaza-verbindungen
DE2963572D1 (en) * 1978-04-11 1982-10-21 Ciba Geigy Ag Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions
DE2823197A1 (de) 1978-05-24 1979-11-29 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4308277A (en) * 1978-08-10 1981-12-29 Ciba-Geigy Corporation 2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4188397A (en) * 1978-09-22 1980-02-12 Smithkline Corporation 2,2-Alkyldiylbis(thio)bis(imidazoles)
US4215135A (en) * 1979-06-08 1980-07-29 E. I. Du Pont De Nemours And Company Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles
DE2856909A1 (de) 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8907656D0 (en) * 1989-04-05 1989-05-17 May & Baker Ltd New compositions of matter
PT786455E (pt) * 1994-09-26 2004-02-27 Shionogi & Co Derivados de imidazol
IL133766A0 (en) * 1997-06-30 2001-04-30 Ortho Mcneil Pharm Inc 2-substituted imidazoles useful in the treatment of inflammatory diseases
DE10222103A1 (de) * 2002-05-17 2003-11-27 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
EP1988081B1 (en) * 2006-02-06 2012-10-17 Taisho Pharmaceutical Co., Ltd Binding inhibitor of sphingosine-1-phosphate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL26729A (en) * 1965-10-21 1970-10-30 Geigy Ag J R 2-mercaptoimidazole derivatives and process for their preparation
US3651080A (en) * 1969-11-07 1972-03-21 Ciba Geigy Corp Certain substituted 2-alkylmercaptoimidazole derivatives
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles

Also Published As

Publication number Publication date
GR61145B (en) 1978-09-27
NZ181731A (en) 1978-11-13
NO146571C (no) 1982-10-27
IL50230A0 (en) 1976-10-31
FI66177B (fi) 1984-05-31
NO146571B (no) 1982-07-19
AR215591A1 (es) 1979-10-31
LU75578A1 (enrdf_load_stackoverflow) 1978-04-13
IL50230A (en) 1979-07-25
SE7607615L (sv) 1977-02-12
AU1671176A (en) 1978-02-16
ES461193A1 (es) 1978-12-01
SU640662A3 (ru) 1978-12-30
PT65464A (en) 1976-09-01
DD126244A5 (enrdf_load_stackoverflow) 1977-07-06
FR2320745B1 (enrdf_load_stackoverflow) 1978-12-22
GB1516908A (en) 1978-07-05
JPS6011702B2 (ja) 1985-03-27
SE428686B (sv) 1983-07-18
PH11857A (en) 1978-08-03
ES450601A1 (es) 1978-01-16
FI762290A7 (enrdf_load_stackoverflow) 1977-02-12
PT65464B (en) 1978-08-02
AR218054A1 (es) 1980-05-15
NL7608915A (nl) 1977-02-15
DK361376A (da) 1977-02-12
FR2320745A1 (fr) 1977-03-11
YU198176A (en) 1982-10-31
NO762754L (enrdf_load_stackoverflow) 1977-02-14
IE44019L (en) 1977-02-11
JPS5223076A (en) 1977-02-21
FI66177C (fi) 1984-09-10
CA1074327A (en) 1980-03-25
HU174707B (hu) 1980-03-28
IE44019B1 (en) 1981-07-29
MX3932E (es) 1981-10-02
CH638791A5 (de) 1983-10-14
DE2635876A1 (de) 1977-03-03

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