AU5016793A - Dual functional anti-inflammatory and immunosuppressive agents - Google Patents

Dual functional anti-inflammatory and immunosuppressive agents

Info

Publication number
AU5016793A
AU5016793A AU50167/93A AU5016793A AU5016793A AU 5016793 A AU5016793 A AU 5016793A AU 50167/93 A AU50167/93 A AU 50167/93A AU 5016793 A AU5016793 A AU 5016793A AU 5016793 A AU5016793 A AU 5016793A
Authority
AU
Australia
Prior art keywords
inflammatory
immunosuppressive agents
dual functional
functional anti
dual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU50167/93A
Inventor
David M Goldstein
San-Bao Hwang
Ralph T Scannell
T. Y Shen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CytoMed Inc
Original Assignee
CytoMed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CytoMed Inc filed Critical CytoMed Inc
Publication of AU5016793A publication Critical patent/AU5016793A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
AU50167/93A 1992-08-20 1993-08-16 Dual functional anti-inflammatory and immunosuppressive agents Abandoned AU5016793A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93339592A 1992-08-20 1992-08-20
US933395 1992-08-20
PCT/US1993/007728 WO1994004537A2 (en) 1992-08-20 1993-08-16 Dual functional anti-inflammatory and immunosuppressive agents

Publications (1)

Publication Number Publication Date
AU5016793A true AU5016793A (en) 1994-03-15

Family

ID=25463868

Family Applications (1)

Application Number Title Priority Date Filing Date
AU50167/93A Abandoned AU5016793A (en) 1992-08-20 1993-08-16 Dual functional anti-inflammatory and immunosuppressive agents

Country Status (5)

Country Link
EP (1) EP0656004A1 (en)
CN (1) CN1090284A (en)
AU (1) AU5016793A (en)
MX (1) MX9305063A (en)
WO (1) WO1994004537A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5463083A (en) * 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
PT650485E (en) 1992-07-13 2001-03-30 Millennium Pharm Inc 2,5-DIARIL-TETRA-HYDRO-THIOPHENES -FURANES AND ANALOGS FOR THE TREATMENT OF INFLAMMATORY AND IMMUNE DISORDERS
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
ES2061406B1 (en) * 1993-05-07 1995-06-01 Uriach & Cia Sa J NEW DERIVATIVES OF 2- (QUINOLINE) WITH PHARMACOLOGICAL ACTIVITY.
US5750565A (en) 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
CN101632669B (en) 2000-08-04 2011-05-18 Dmi生物科学公司 Method of using diketopiperazines and composition containing them
KR20150080004A (en) 2003-05-15 2015-07-08 앰피오 파마슈티컬스 인코퍼레이티드 Treatment of t-cell mediated diseases
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
CA2810844C (en) 2010-09-07 2017-03-21 Dmi Acquisition Corp. Diketopiperazine compositions for the treatment of metabolic syndrome and related conditions
CA2846464A1 (en) 2011-10-10 2013-04-18 Ampio Pharmaceuticals, Inc. Implantable medical devices with increased immune tolerance, and methods for making and implanting
BR112014007675A2 (en) 2011-10-10 2017-04-18 Ampio Pharmaceuticals Inc degenerative joint disease treatment
EP2771007B1 (en) 2011-10-28 2018-04-04 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
AU2015305611B2 (en) 2014-08-18 2020-04-23 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
WO2016209969A1 (en) 2015-06-22 2016-12-29 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
WO2023012130A1 (en) 2021-08-02 2023-02-09 F. Hoffmann-La Roche Ag New cyclopenta-thieno-diazepine derivatives as gaba a gamma1 pam

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757084A (en) * 1984-02-29 1988-07-12 Merck & Co., Inc. 2,5-diaryl tetrahydrothiophenes and analogs thereof as PAF-antagonists
DE3502392A1 (en) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim NEW THIENO-TRIAZOLO-1,4-DIAZEPINO-2-CARBONIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS
PT81492B (en) * 1985-09-17 1988-03-03 Ciba Geigy Ag METHOD FOR PREPARING NEW FLORORATED RESORCINE ETEREES
PL154186B1 (en) * 1987-07-15 1991-07-31 Wellcome Found Method for manufacturing arylic derivatives of the hydroxamic acid
JPH0288553A (en) * 1988-07-14 1990-03-28 Wellcome Found Ltd:The Anti-inflammatory aryl derivative
FR2653119B1 (en) * 1989-10-18 1994-08-05 Lipha NOVEL ARYLOXY ALCOYL BENZENES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
WO1991012253A1 (en) * 1990-02-07 1991-08-22 Pfizer Inc. Tetralin and chroman derivatives useful in the treatment of asthma, arthritis, and related diseases
RO109450B1 (en) * 1990-05-09 1995-02-28 Pfizer Derivates of imidazo (4,5-c) pyridine, preparation processes thereof, compositions which contain them thereof and treatment method
DE4027470A1 (en) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg NEW HETRAZEPINOIDE AMIDE
ZA919797B (en) * 1990-12-13 1992-10-28 Smithkline Beecham Corp Bicyclo-5,6-dihydro-7h-pyrrolo-1,20-imidazol-7-ols and 7-ones

Also Published As

Publication number Publication date
WO1994004537A2 (en) 1994-03-03
MX9305063A (en) 1994-04-29
WO1994004537A3 (en) 1994-10-27
EP0656004A1 (en) 1995-06-07
CN1090284A (en) 1994-08-03

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