AU4234796A - Rapid detection and identification of nucleic acid variants and pathogens - Google Patents

Rapid detection and identification of nucleic acid variants and pathogens

Info

Publication number
AU4234796A
AU4234796A AU42347/96A AU4234796A AU4234796A AU 4234796 A AU4234796 A AU 4234796A AU 42347/96 A AU42347/96 A AU 42347/96A AU 4234796 A AU4234796 A AU 4234796A AU 4234796 A AU4234796 A AU 4234796A
Authority
AU
Australia
Prior art keywords
nucleic acid
cleavage
stranded
dna
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42347/96A
Other languages
English (en)
Inventor
Mary Ann D. Brow
James E Dahlberg
Lance Fors
Laura M Heisler
Victor I. Lyamichev
Mary C Oldenburg
David Michael Olive
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Third Wave Technologies Inc
Original Assignee
Third Wave Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/484,956 external-priority patent/US5843654A/en
Priority claimed from US08/520,946 external-priority patent/US6372424B1/en
Application filed by Third Wave Technologies Inc filed Critical Third Wave Technologies Inc
Publication of AU4234796A publication Critical patent/AU4234796A/en
Priority to AU44446/99A priority Critical patent/AU4444699A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU42347/96A 1994-11-09 1995-11-09 Rapid detection and identification of nucleic acid variants and pathogens Abandoned AU4234796A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU44446/99A AU4444699A (en) 1994-11-09 1999-08-12 Rapid detection and indentification of nucleic acid variants and pathogens

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US33716494A 1994-11-09 1994-11-09
US337164 1994-11-09
US40260195A 1995-03-09 1995-03-09
US402601 1995-03-09
US484956 1995-06-07
US08/484,956 US5843654A (en) 1992-12-07 1995-06-07 Rapid detection of mutations in the p53 gene
US520946 1995-08-30
US08/520,946 US6372424B1 (en) 1995-08-30 1995-08-30 Rapid detection and identification of pathogens
PCT/US1995/014673 WO1996015267A1 (fr) 1994-11-09 1995-11-09 Detection et identification rapides de variants de l'acide nucleique et d'agents pathogenes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU44446/99A Division AU4444699A (en) 1994-11-09 1999-08-12 Rapid detection and indentification of nucleic acid variants and pathogens

Publications (1)

Publication Number Publication Date
AU4234796A true AU4234796A (en) 1996-06-06

Family

ID=27502560

Family Applications (2)

Application Number Title Priority Date Filing Date
AU42347/96A Abandoned AU4234796A (en) 1994-11-09 1995-11-09 Rapid detection and identification of nucleic acid variants and pathogens
AU44446/99A Abandoned AU4444699A (en) 1994-11-09 1999-08-12 Rapid detection and indentification of nucleic acid variants and pathogens

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU44446/99A Abandoned AU4444699A (en) 1994-11-09 1999-08-12 Rapid detection and indentification of nucleic acid variants and pathogens

Country Status (5)

Country Link
EP (1) EP0788557A4 (fr)
JP (1) JPH10509322A (fr)
AU (2) AU4234796A (fr)
CA (1) CA2203627C (fr)
WO (1) WO1996015267A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994069A (en) * 1996-01-24 1999-11-30 Third Wave Technologies, Inc. Detection of nucleic acids by multiple sequential invasive cleavages
US5922575A (en) * 1994-04-18 1999-07-13 Mayo Foundation For Medical Education & Research Mutations in the katG gene useful for detection of M. tuberculosis
US5985557A (en) * 1996-01-24 1999-11-16 Third Wave Technologies, Inc. Invasive cleavage of nucleic acids
JP3665648B2 (ja) * 1996-01-24 2005-06-29 サード ウェーブ テクノロジーズ，インコーポレーテッド 核酸の侵入的開裂
EP0966542B1 (fr) * 1996-11-29 2008-11-12 Third Wave Technologies, Inc. Agents de clivage ameliores
US8182991B1 (en) 1997-11-26 2012-05-22 Third Wave Technologies, Inc. FEN-1 endonucleases, mixtures and cleavage methods
GB9918150D0 (en) * 1999-08-03 1999-10-06 Univ Sheffield Nuclease variant
AU2001268513A1 (en) 2000-06-17 2002-01-02 Third Wave Technologies, Inc. Nucleic acid accessible hybridization sites
WO2002008265A2 (fr) * 2000-07-19 2002-01-31 Pharmacia & Upjohn Company Sequence nucleotidique complete du gene de la proteine ribosomale de staphylococcus aureus, s20, et methodes d'identification de substances antibacteriennes
JP2011072222A (ja) * 2009-09-29 2011-04-14 Kitasato Otsuka Biomedical Assay Kenkyusho:Kk 標的核酸の検出方法
WO2016012508A1 (fr) * 2014-07-23 2016-01-28 Steffen Mergemeier Procédé de détection d'une septicémie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3179481B2 (ja) * 1990-06-27 2001-06-25 プリンストン ユニバーシティ 突然変異体ｐ５３検出用プローブ
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5422253A (en) * 1992-12-07 1995-06-06 Wisconsin Alumni Research Foundation Method of site specific nucleic acid cleavage
US5541311A (en) * 1992-12-07 1996-07-30 Third Wave Technologies, Inc. Nucleic acid encoding synthesis-deficient thermostable DNA polymerase

Also Published As

Publication number Publication date
CA2203627A1 (fr) 1996-05-23
AU4444699A (en) 1999-10-14
CA2203627C (fr) 2000-06-06
JPH10509322A (ja) 1998-09-14
WO1996015267A1 (fr) 1996-05-23
EP0788557A1 (fr) 1997-08-13
EP0788557A4 (fr) 2003-08-06

Similar Documents

Publication Publication Date Title
US6372424B1 (en) Rapid detection and identification of pathogens
US6673616B1 (en) Methods and compositions for characterizing nucleic acids
US5843669A (en) Cleavage of nucleic acid acid using thermostable methoanococcus jannaschii FEN-1 endonucleases
US7785852B2 (en) Cleavage of nucleic acids
US5843654A (en) Rapid detection of mutations in the p53 gene
AU694736B2 (en) 5' Nucleases derived from thermostable DNA polymerase
US5888780A (en) Rapid detection and identification of nucleic acid variants
US5719028A (en) Cleavase fragment length polymorphism
US6706471B1 (en) Detection of nucleic acid sequences by invader-directed cleavage
AU731062B2 (en) Invasive cleavage of nucleic acids
US6348314B1 (en) Invasive cleavage of nucleic acids
AU737449B2 (en) FEN-1 endonucleases, mixtures and cleavage methods
US20020197623A1 (en) Nucleic acid detection assays
EP0994964A1 (fr) Detection d'acides nucleique par clivages sequentiels invasifs multiples
US20030152971A1 (en) Methods and compositions for detecting target sequences
US20040072182A1 (en) Methods and compositions for detecting target sequences
AU4234796A (en) Rapid detection and identification of nucleic acid variants and pathogens
AU4058802A (en) Rapid detection and identification of nucleic acid variants and pathogens
AU738849B2 (en) Detection of nuceic acids by multiple sequential invasive cleavages
AU781188B2 (en) Detection of nucleic acids by multiple sequential invasive cleavages