AU3860793A - Self-sticking matrix system for the sustained transcutaneous release of piribedil - Google Patents
Self-sticking matrix system for the sustained transcutaneous release of piribedilInfo
- Publication number
- AU3860793A AU3860793A AU38607/93A AU3860793A AU3860793A AU 3860793 A AU3860793 A AU 3860793A AU 38607/93 A AU38607/93 A AU 38607/93A AU 3860793 A AU3860793 A AU 3860793A AU 3860793 A AU3860793 A AU 3860793A
- Authority
- AU
- Australia
- Prior art keywords
- piribedil
- self
- sustained
- matrix system
- transcutaneous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OQDPVLVUJFGPGQ-UHFFFAOYSA-N 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine Chemical compound C=1C=C2OCOC2=CC=1CN(CC1)CCN1C1=NC=CC=N1 OQDPVLVUJFGPGQ-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004310 piribedil Drugs 0.000 title abstract 3
- 239000011159 matrix material Substances 0.000 title abstract 2
- 230000002459 sustained effect Effects 0.000 title 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 238000013265 extended release Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Addiction (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Plural Heterocyclic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Matrix system made up of ethylene/vinyl acetate copolymer, self-adhesive for the extended release of piribedil. This system ensures the continuous and uniform diffusion of piribedil by a transcutaneous route.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9206037 | 1992-05-19 | ||
FR9206037A FR2691361B1 (en) | 1992-05-19 | 1992-05-19 | SELF-ADHESIVE MATRIX SYSTEM FOR THE EXTENDED RELEASE OF THE PIRIBEDIL BY TRANSCUTANEOUS ROUTE. |
Publications (2)
Publication Number | Publication Date |
---|---|
AU3860793A true AU3860793A (en) | 1993-11-25 |
AU656266B2 AU656266B2 (en) | 1995-01-27 |
Family
ID=9429912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU38607/93A Ceased AU656266B2 (en) | 1992-05-19 | 1993-05-18 | Self-sticking matrix system for the sustained transcutaneous release of piribedil |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0571264B1 (en) |
JP (1) | JPH0632738A (en) |
AT (1) | ATE173623T1 (en) |
AU (1) | AU656266B2 (en) |
CA (1) | CA2096511A1 (en) |
DE (1) | DE69322201T2 (en) |
DK (1) | DK0571264T3 (en) |
ES (1) | ES2127259T3 (en) |
FR (1) | FR2691361B1 (en) |
NZ (1) | NZ247648A (en) |
ZA (1) | ZA933508B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2675383B1 (en) * | 1991-04-18 | 1995-05-12 | Bernard Aranda | USE OF A MEDICINAL PRODUCT FOR THE MANUFACTURE OF A MEDICINAL PRODUCT FOR THE TREATMENT OF HYPERACTIVE OR UNSTABLE BLADDER. |
US5840327A (en) * | 1995-08-21 | 1998-11-24 | Alza Corporation | Transdermal drug delivery device having enhanced adhesion |
FR2744130B1 (en) * | 1996-01-31 | 1998-03-20 | Atohaas Holding Cv | ADHESIVE COMPOSITION FOR (CO) POLYMER (METH) ACRYLIC MATERIALS |
CN103373991A (en) * | 2013-07-12 | 2013-10-30 | 安徽安腾药业有限责任公司 | Method for preparing piribedil in high-purity high-yield manner |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2355502A1 (en) * | 1976-06-23 | 1978-01-20 | Roussel Uclaf | APPLICATION AS A MEDICINAL PRODUCT OF A DERIVATIVE OF PIPERAZINE AND ITS SALTS |
DE68917292T2 (en) * | 1988-02-26 | 1995-02-02 | Riker Laboratories Inc | TRANSDERMAL ESTRADIOL AS A THERAPEUTIC SYSTEM. |
FR2664815B1 (en) | 1990-07-23 | 1994-11-04 | Adir | SELF-ADHESIVE MATRIX SYSTEM FOR THE EXTENDED RELEASE OF THE PIRIBEDIL BY TRANSCUTANEOUS ROUTE. |
GB9102089D0 (en) * | 1991-01-31 | 1991-03-13 | Johnson & Johnson Medical | Net wound dressings |
-
1992
- 1992-05-19 FR FR9206037A patent/FR2691361B1/en not_active Expired - Fee Related
-
1993
- 1993-05-17 JP JP5115044A patent/JPH0632738A/en active Pending
- 1993-05-18 DK DK93401262T patent/DK0571264T3/en active
- 1993-05-18 CA CA002096511A patent/CA2096511A1/en not_active Abandoned
- 1993-05-18 AT AT93401262T patent/ATE173623T1/en not_active IP Right Cessation
- 1993-05-18 EP EP93401262A patent/EP0571264B1/en not_active Expired - Lifetime
- 1993-05-18 AU AU38607/93A patent/AU656266B2/en not_active Ceased
- 1993-05-18 ES ES93401262T patent/ES2127259T3/en not_active Expired - Lifetime
- 1993-05-18 DE DE69322201T patent/DE69322201T2/en not_active Expired - Fee Related
- 1993-05-19 NZ NZ247648A patent/NZ247648A/en unknown
- 1993-05-19 ZA ZA933508A patent/ZA933508B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JPH0632738A (en) | 1994-02-08 |
AU656266B2 (en) | 1995-01-27 |
DE69322201T2 (en) | 1999-06-24 |
ATE173623T1 (en) | 1998-12-15 |
DE69322201D1 (en) | 1999-01-07 |
ES2127259T3 (en) | 1999-04-16 |
NZ247648A (en) | 1995-01-27 |
CA2096511A1 (en) | 1993-11-20 |
DK0571264T3 (en) | 1999-08-09 |
EP0571264B1 (en) | 1998-11-25 |
EP0571264A1 (en) | 1993-11-24 |
ZA933508B (en) | 1993-12-10 |
FR2691361A1 (en) | 1993-11-26 |
FR2691361B1 (en) | 1994-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Assignment registered |
Owner name: LES LABORATOIRES SERVIER Free format text: FORMER OWNER WAS: ADIR ET COMPAGNIE |