AU2640997A - 3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics - Google Patents

3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics

Info

Publication number
AU2640997A
AU2640997A AU26409/97A AU2640997A AU2640997A AU 2640997 A AU2640997 A AU 2640997A AU 26409/97 A AU26409/97 A AU 26409/97A AU 2640997 A AU2640997 A AU 2640997A AU 2640997 A AU2640997 A AU 2640997A
Authority
AU
Australia
Prior art keywords
tetrahydroisoquinoline
azabicyclo
therapeutics
methyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU26409/97A
Other languages
English (en)
Inventor
Pascal George
Benoit Marabout
Jean-Pierre Merly
Mireille Sevrin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of AU2640997A publication Critical patent/AU2640997A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU26409/97A 1996-04-12 1997-04-10 3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics Abandoned AU2640997A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9604565A FR2747386B1 (fr) 1996-04-12 1996-04-12 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
FR9604565 1996-04-12
PCT/FR1997/000634 WO1997038998A1 (fr) 1996-04-12 1997-04-10 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
AU2640997A true AU2640997A (en) 1997-11-07

Family

ID=9491132

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26409/97A Abandoned AU2640997A (en) 1996-04-12 1997-04-10 3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics

Country Status (22)

Country Link
EP (1) EP0892800A1 (ru)
JP (1) JP2000512620A (ru)
KR (1) KR20000005392A (ru)
CN (1) CN1216046A (ru)
AR (1) AR008587A1 (ru)
AU (1) AU2640997A (ru)
BG (1) BG102779A (ru)
BR (1) BR9708654A (ru)
CA (1) CA2251335A1 (ru)
CO (1) CO4900067A1 (ru)
CZ (1) CZ326898A3 (ru)
EE (1) EE9800396A (ru)
FR (1) FR2747386B1 (ru)
IL (1) IL126473A0 (ru)
NO (1) NO984736L (ru)
NZ (1) NZ332257A (ru)
PL (1) PL329243A1 (ru)
SK (1) SK141598A3 (ru)
TR (1) TR199801839T2 (ru)
TW (1) TW407158B (ru)
WO (1) WO1997038998A1 (ru)
ZA (1) ZA973124B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102131790A (zh) * 2008-06-27 2011-07-20 H.隆德贝克有限公司 新型苯酚型和儿茶酚型胺及其前药
JP7015092B2 (ja) 2016-07-28 2022-02-02 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する含窒素縮環化合物
JPWO2019146739A1 (ja) 2018-01-26 2021-01-07 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する縮環化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU895334D0 (en) * 1986-07-30 1990-01-28 Sandoz Ag Process for the preparation of nasal pharmaceutical compositions
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
WO1997038998A1 (fr) 1997-10-23
JP2000512620A (ja) 2000-09-26
NZ332257A (en) 1999-03-29
CZ326898A3 (cs) 1999-01-13
ZA973124B (en) 1997-11-05
FR2747386B1 (fr) 1998-05-15
EE9800396A (et) 1999-06-15
NO984736L (no) 1998-11-23
PL329243A1 (en) 1999-03-15
SK141598A3 (en) 1999-03-12
CN1216046A (zh) 1999-05-05
KR20000005392A (ko) 2000-01-25
BG102779A (en) 1999-09-30
TW407158B (en) 2000-10-01
EP0892800A1 (fr) 1999-01-27
FR2747386A1 (fr) 1997-10-17
CA2251335A1 (en) 1997-10-23
AR008587A1 (es) 2000-02-09
IL126473A0 (en) 1999-08-17
BR9708654A (pt) 1999-08-03
CO4900067A1 (es) 2000-03-27
TR199801839T2 (ru) 1998-12-21
NO984736D0 (no) 1998-10-09

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted