AU2136788A - Production of ricin toxins in a baculovirus-insect cell expression system - Google Patents

Production of ricin toxins in a baculovirus-insect cell expression system

Info

Publication number
AU2136788A
AU2136788A AU21367/88A AU2136788A AU2136788A AU 2136788 A AU2136788 A AU 2136788A AU 21367/88 A AU21367/88 A AU 21367/88A AU 2136788 A AU2136788 A AU 2136788A AU 2136788 A AU2136788 A AU 2136788A
Authority
AU
Australia
Prior art keywords
baculovirus
production
expression system
insect cell
cell expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU21367/88A
Other languages
English (en)
Inventor
Robin Clark
L.L. Houston
Julie A. Lane
Michael Piatak Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of AU2136788A publication Critical patent/AU2136788A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU21367/88A 1987-07-24 1988-07-20 Production of ricin toxins in a baculovirus-insect cell expression system Abandoned AU2136788A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7712687A 1987-07-24 1987-07-24
US077126 1987-07-24
US15377888A 1988-02-08 1988-02-08
US153778 1988-02-08

Publications (1)

Publication Number Publication Date
AU2136788A true AU2136788A (en) 1989-03-01

Family

ID=26758913

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21367/88A Abandoned AU2136788A (en) 1987-07-24 1988-07-20 Production of ricin toxins in a baculovirus-insect cell expression system

Country Status (3)

Country Link
AU (1) AU2136788A (fr)
IL (1) IL87193A0 (fr)
WO (1) WO1989001037A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU626867B2 (en) * 1988-05-31 1992-08-13 Centre National De La Recherche Scientifique (Cnrs) Modified baculovirus, method for preparing it and its use as an expression vector of genes

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69734656T2 (de) 1996-04-30 2006-08-10 Twinstrand Therapeutics Inc., Burnaby Antivirale variante von ricin-proteinen
KR19980043226A (ko) * 1996-12-02 1998-09-05 박영설 에어백이 장착된 뒷굽없는 신발밑창
WO1998018820A1 (fr) * 1996-10-28 1998-05-07 Medical University Of South Carolina Procedes et compositions relatifs a des immunotoxines de la proteine de fusion du ricin, pour le traitement du cancer et de maladies auto-immunes
MXPA06008507A (es) 2004-02-02 2008-02-13 Ambrx Inc Cuatro polipeptidos en haz helicoidal humanos modificados y sus usos.
KR101699142B1 (ko) 2004-06-18 2017-01-23 암브룩스, 인코포레이티드 신규 항원-결합 폴리펩티드 및 이의 용도
NZ555308A (en) 2004-12-22 2010-10-29 Ambrx Inc Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
BRPI0519568C8 (pt) 2004-12-22 2022-06-14 Ambrx Inc Aminoacil-trna sintetase (rs), composições que compreendem a dita aminoacil-trna sintetase, célula de levedura, célula fúngica, célula não eucariótica, vetor que codifica uma rs, polinucleotídeo e ainda método para produzir um polipeptídeo em uma célula com um aminoácido selecionado em uma posição especificada
EP2284191A3 (fr) 2004-12-22 2011-07-20 Ambrx, Inc. Procédé de préparation de hGH
KR20070100299A (ko) 2004-12-22 2007-10-10 암브룩스, 인코포레이티드 재조합 인간 성장 호르몬의 발현 및 정제 방법
NZ555386A (en) 2004-12-22 2011-01-28 Ambrx Inc Formulations of human growth hormone comprising a non-naturally encoded amino acid
MX2007015058A (es) 2005-06-03 2008-01-28 Ambrx Inc Moleculas de interferon humano mejoradas y sus usos.
CA2626522A1 (fr) 2005-11-16 2007-05-24 Ambrx, Inc. Procedes et compositions comprenant des acides amines non naturels
DK2064333T3 (da) 2006-09-08 2014-05-05 Ambrx Inc Suppressor-trna-transkription i hvirveldyrceller
CN106008699A (zh) 2006-09-08 2016-10-12 Ambrx公司 经修饰的人类血浆多肽或Fc骨架和其用途
CN106190983B (zh) 2006-09-08 2019-05-28 Ambrx公司 用于脊椎动物细胞的杂合抑制tRNA
CN104163864B (zh) 2007-03-30 2017-08-01 Ambrx公司 经修饰fgf‑21多肽和其用途
US8114630B2 (en) 2007-05-02 2012-02-14 Ambrx, Inc. Modified interferon beta polypeptides and their uses
NZ603812A (en) 2007-11-20 2014-06-27 Ambrx Inc Modified insulin polypeptides and their uses
JP5702150B2 (ja) 2008-02-08 2015-04-15 アンブルックス, インコーポレイテッドAmbrx, Inc. 修飾されているレプチンポリペプチドおよびそれらの使用
EP3225248B1 (fr) 2008-07-23 2023-06-07 Ambrx, Inc. Polypeptides g-csf bovins modifiés et leurs utilisations
PT2337846T (pt) 2008-09-26 2018-04-05 Ambrx Inc Vacinas e microrganismos dependentes da replicação de aminoácidos não naturais
KR101647164B1 (ko) 2008-09-26 2016-08-09 암브룩스, 인코포레이티드 변형된 동물 에리트로포이에틴 폴리펩티드 및 이의 용도
AU2010341518B2 (en) 2009-12-21 2014-01-09 Ambrx, Inc. Modified porcine somatotropin polypeptides and their uses
CN102753573A (zh) 2009-12-21 2012-10-24 Ambrx公司 经过修饰的牛促生长素多肽和其用途
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
PL2605789T3 (pl) 2010-08-17 2019-11-29 Ambrx Inc Zmodyfikowane polipeptydy relaksyny i ich zastosowania
TWI480288B (zh) 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
UY36370A (es) 2014-10-24 2016-04-29 Bristol Myers Squibb Company Una Corporación Del Estado De Delaware Polipéptidos fgf-21 modificados y sus usos
BR112019016139A2 (pt) 2017-02-08 2020-04-07 Bristol-Myers Squibb Company polipeptídio de relaxina modificada compreendendo um melhorador farmacocinético e usos do mesmo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485810T2 (de) * 1983-05-27 1992-12-10 Texas A & M University Syst Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors.
EP0145111B1 (fr) * 1983-07-15 1990-05-09 The University Of Warwick Séquence d'ADN codant pour une toxine du type de ricine ou une partie

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU626867B2 (en) * 1988-05-31 1992-08-13 Centre National De La Recherche Scientifique (Cnrs) Modified baculovirus, method for preparing it and its use as an expression vector of genes

Also Published As

Publication number Publication date
IL87193A0 (en) 1988-12-30
WO1989001037A1 (fr) 1989-02-09

Similar Documents

Publication Publication Date Title
AU2136788A (en) Production of ricin toxins in a baculovirus-insect cell expression system
AU6717587A (en) Production of bacterial nitralase in transformed host cell
AU3969689A (en) Bio-reactor cell culture process
AU576551B2 (en) Production plant with modular members
AU588840B2 (en) Improvements in or relating to a process for purifying proteins
DE3480259D1 (en) Enteric-soluble preparations and a process for their production
AU1478288A (en) Improvements in or relating to a connector
AU7601291A (en) Ether production
AU6403086A (en) Genetic females in hybrid seed production
EP0159165A3 (en) Water-absorbing laminate and production process thereof
AU4334185A (en) Control of plunger in forming parison
AU2534688A (en) Improvements in or relating to fabric production
AU590651B2 (en) Improved xylene production in a dehydrocyclodimerization process
AU584596B2 (en) Continuous bioreactor and process
AU574021B2 (en) Battery and process for its production
AU2179588A (en) Method and means for the production of a micro-organism cell mass
AU5093085A (en) Improvements in and relating to the production of transfers
AU2575088A (en) Measuring convergence in a mine
AU4382285A (en) Opticalfibre preform manufacture
AU583489B2 (en) 8alpha-acylamino-ergolines uses and production thereof
AU579188B2 (en) Silica molding and process for its production
AU2021088A (en) Improvements in or relating to hybrid seed production
AU589465B2 (en) Product recovery in a dehydrocyclodimerization and other hydrogen producing processes
AU8225187A (en) Reduced-stability alpha-amylase and process for its production
AU2810089A (en) Production of proteins in plants