AU2021409196A1 - Method for producing naive human ips cells from somatic cells - Google Patents
Method for producing naive human ips cells from somatic cells Download PDFInfo
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- AU2021409196A1 AU2021409196A1 AU2021409196A AU2021409196A AU2021409196A1 AU 2021409196 A1 AU2021409196 A1 AU 2021409196A1 AU 2021409196 A AU2021409196 A AU 2021409196A AU 2021409196 A AU2021409196 A AU 2021409196A AU 2021409196 A1 AU2021409196 A1 AU 2021409196A1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/602—Sox-2
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/603—Oct-3/4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
- C12N2506/115—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells from monocytes, from macrophages
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Transplantation (AREA)
- Developmental Biology & Embryology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020217472 | 2020-12-25 | ||
| JP2020-217472 | 2020-12-25 | ||
| PCT/JP2021/048397 WO2022138964A1 (ja) | 2020-12-25 | 2021-12-24 | 体細胞からのナイーブ型ヒトiPS細胞製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2021409196A1 true AU2021409196A1 (en) | 2023-08-03 |
| AU2021409196A9 AU2021409196A9 (en) | 2024-05-16 |
Family
ID=82158245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021409196A Pending AU2021409196A1 (en) | 2020-12-25 | 2021-12-24 | Method for producing naive human ips cells from somatic cells |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240060051A1 (https=) |
| EP (1) | EP4269571A4 (https=) |
| JP (1) | JPWO2022138964A1 (https=) |
| KR (1) | KR20230126717A (https=) |
| CN (1) | CN116802275A (https=) |
| AU (1) | AU2021409196A1 (https=) |
| CA (1) | CA3203232A1 (https=) |
| IL (1) | IL303975A (https=) |
| WO (1) | WO2022138964A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116004512A (zh) * | 2022-12-30 | 2023-04-25 | 深圳市康宁医院 | 一种利用外泌体制备诱导性多能干细胞的方法及其试剂和应用 |
| AU2024232721A1 (en) * | 2023-03-03 | 2025-10-09 | Kyoto University | Method for producing primed pluripotent stem cells |
| WO2025151477A1 (en) * | 2024-01-09 | 2025-07-17 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Methods of producing rejuvenated human somatic cells, compositions, and methods of use |
Family Cites Families (38)
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| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| DK0864645T3 (da) | 1995-10-31 | 2005-10-24 | Dnavec Research Inc | Negativstrenget RNA-virusvektor med autonom replikeringsaktivitet |
| DK0863202T3 (da) | 1995-11-01 | 2010-09-27 | Dnavec Research Inc | Rekombinant Sendai-virus |
| US6130313A (en) | 1997-10-02 | 2000-10-10 | Clontech Laboratories, Inc. | Rapidly degrading GFP-fusion proteins |
| KR100739938B1 (ko) | 1999-05-18 | 2007-07-16 | 가부시키가이샤 디나벡크 겐큐쇼 | 엔벨로프 유전자 결손 파라믹소과 바이러스 벡터 |
| ATE399206T1 (de) | 1999-05-18 | 2008-07-15 | Dnavec Research Inc | Ribonukleoproteinkomplex aus paramyxovirus |
| EP1211318B1 (en) | 1999-09-06 | 2007-08-08 | DNAVEC Research, Inc. | Paramyxoviruses comprising a modified transcription start sequence |
| JPWO2003025570A1 (ja) | 2001-09-18 | 2004-12-24 | 株式会社ディナベック研究所 | 粒子形成能が低下した(−)鎖rnaウィルスベクターの検査方法および製造方法 |
| JP4528623B2 (ja) | 2002-09-16 | 2010-08-18 | プロメガ コーポレイション | 迅速分解性レポーター融合タンパク質 |
| JP4999330B2 (ja) | 2004-01-22 | 2012-08-15 | 株式会社ディナベック研究所 | サイトメガロウイルスエンハンサーおよびニワトリβ−アクチンプロモーターを含むハイブリッドプロモーターを利用したマイナス鎖RNAウイルスベクターの製造方法 |
| JP4901471B2 (ja) | 2004-02-19 | 2012-03-21 | 国立大学法人京都大学 | 体細胞核初期化物質のスクリーニング方法 |
| WO2006137517A1 (ja) | 2005-06-24 | 2006-12-28 | Dnavec Corporation | 幼少個体への遺伝子導入用ベクター |
| JP4944781B2 (ja) | 2005-09-15 | 2012-06-06 | 独立行政法人科学技術振興機構 | テトラサイクリン系抗生物質によるタンパク質分解制御法 |
| BRPI0619794B8 (pt) | 2005-12-13 | 2022-06-14 | Univ Kyoto | Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas |
| CA2636600A1 (en) | 2006-01-17 | 2007-07-26 | Dnavec Corporation | Novel protein expression system |
| KR20090052857A (ko) | 2006-07-13 | 2009-05-26 | 디나벡크 가부시키가이샤 | 비복제형 파라믹소바이러스과 바이러스 벡터 |
| US8173792B2 (en) | 2007-02-09 | 2012-05-08 | The Board Of Trustees Of The Leland Stanford Junior University | Method for regulating protein function in cells using synthetic small molecules |
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| JP5605658B2 (ja) | 2009-04-30 | 2014-10-15 | 国立大学法人大阪大学 | 哺乳類細胞におけるタンパク質分解誘導方法 |
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2021
- 2021-12-24 JP JP2022571717A patent/JPWO2022138964A1/ja active Pending
- 2021-12-24 KR KR1020237024855A patent/KR20230126717A/ko active Pending
- 2021-12-24 EP EP21911101.0A patent/EP4269571A4/en active Pending
- 2021-12-24 CN CN202180091434.5A patent/CN116802275A/zh active Pending
- 2021-12-24 IL IL303975A patent/IL303975A/en unknown
- 2021-12-24 US US18/269,270 patent/US20240060051A1/en active Pending
- 2021-12-24 WO PCT/JP2021/048397 patent/WO2022138964A1/ja not_active Ceased
- 2021-12-24 CA CA3203232A patent/CA3203232A1/en active Pending
- 2021-12-24 AU AU2021409196A patent/AU2021409196A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021409196A9 (en) | 2024-05-16 |
| CN116802275A (zh) | 2023-09-22 |
| EP4269571A4 (en) | 2025-01-01 |
| KR20230126717A (ko) | 2023-08-30 |
| EP4269571A1 (en) | 2023-11-01 |
| JPWO2022138964A1 (https=) | 2022-06-30 |
| WO2022138964A1 (ja) | 2022-06-30 |
| IL303975A (en) | 2023-08-01 |
| US20240060051A1 (en) | 2024-02-22 |
| CA3203232A1 (en) | 2022-06-30 |
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