AU2021104815A4 - Traditional Chinese Veterinary Medicine Containing Selenium-enriched Probiotics for Enhancing Chicken Resistance and Formulation Thereof - Google Patents
Traditional Chinese Veterinary Medicine Containing Selenium-enriched Probiotics for Enhancing Chicken Resistance and Formulation Thereof Download PDFInfo
- Publication number
- AU2021104815A4 AU2021104815A4 AU2021104815A AU2021104815A AU2021104815A4 AU 2021104815 A4 AU2021104815 A4 AU 2021104815A4 AU 2021104815 A AU2021104815 A AU 2021104815A AU 2021104815 A AU2021104815 A AU 2021104815A AU 2021104815 A4 AU2021104815 A4 AU 2021104815A4
- Authority
- AU
- Australia
- Prior art keywords
- parts
- radix
- traditional chinese
- selenium
- chinese veterinary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Polymers & Plastics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Animal Husbandry (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a traditional Chinese veterinary drug containing selenium
enriched probiotics for enhancing chicken resistance. Is prepared from the following raw
materials in parts by weight: 16-40 parts of Radix Astragali seu Hedysari, 16-40 parts of
Fructus Crataegi, 16-40 parts of Radix Morindae Officinalis, 12-30 parts of Radix Codonopsis,
12-30 parts of Poria, 12-30 parts of Radix Glycyrrhizae, 12-20 parts of Radix et Caulis
Acanthopanacis Senticosi, 12-30 parts of Cortex Eucommiae, 12-30 parts of Herba Epimedii,
12-30 parts of Fructus Ligustri Lucidi, 12-30 parts of Radix Isatidis, 12-30 parts of Bulbus
Bulbus Fritillaria, 12-30 parts of Herba Taraxaci, 8-20 parts of Radix Polygoni Multiflori, 8
20 parts of Rhizoma Coptidis, 8-20 parts of Cyrtomium Rhizome, 9-27 parts of yeast selenium
of 2000mg/kg and 40 parts of Bacillus subtilis. The invention not only has the functions of
invigorating qi and blood, nourishing liver and kidney, clearing away heat and toxic materials,
regulating intestines and stomach, improving internal environment of organism, promoting
chicken growth, etc., but also can solve the problems of chicken resistance decline, weak
immunity, microbial drug resistance, drug and heavy metal residues, etc. in modem breeding.
Description
Traditional Chinese Veterinary Medicine Containing Selenium-enriched
Probiotics for Enhancing Chicken Resistance and Formulation Thereof
The invention relates to the preparation of a feed additive, and mainly relates to a
traditional Chinese veterinary drug containing selenium-enriched probiotics for
enhancing chicken resistance and formulation thereof.
Chinese veterinary medicine, as a traditional national medicine in China, has a
history of development and application for thousands of years. Since the compilation
of Si Mu An Ji Ji (a book for treating horse diseases) in Tang Dynasty, it marks the
initial formation of Chinese veterinary medicine system. To the Yuan Dynasty, The
Theory of Dredging Horses and Passing through Xuans (a book for treating horse
diseases) and the Ming Dynasty, Yuan Heng Healing Horses (a book for treating
horse diseases) and other Chinese veterinary classics came out, which laid a solid
foundation for the rapid development of animal husbandry. Since 1949, great
importance has been attached to the development of traditional Chinese medicine, and
Chinese veterinary drugs have been widely used in the prevention and treatment of
livestock and poultry diseases, which has accumulated a large number of diagnosis
and treatment techniques and empirical prescriptions for clinical veterinary practice
and application.
In the long-term clinical practice, Chinese Veterinary Medicine has formed a
perfect theory of disease prevention, which pays attention to the treatment principles of prevention before disease and balance. At the same time, Chinese veterinary medicine attaches importance to nourishing and conditioning the innate liver and kidney and the acquired spleen and stomach, which coincides with the immune organs and digestive and metabolic organs of modem medicine. Therefore, nourishing and conditioning the spleen and stomach, liver and kidney of livestock and poultry has scientific basis for enhancing the body resistance and promoting the growth of livestock and poultry.
In the long-term development process, Chinese veterinary medicine has formed a
large number of empirical formulations, such as "Shiquan Dabu Decoction" for
enriching blood; "Liuwei Dihuang Pill" for nourishing liver and kidney; "Buzhong
Yiqi Decoction" (the three are traditional Chinese medicines), etc. With the
development of modem biomedicine, it has also been confirmed that Radix Astragali
seu Hedysari, i, Radix Codonopsis, Fructus Corn, Radix Glycyrrhizae, Poria have
many biological activities such as enhancing immunity, anti-inflammation,
anti-oxidation, protecting liver and strengthening heart. This has found a new solution
to the problems of livestock and poultry resistance decline, stress response, excessive
addition and abuse of antibiotics, microbial drug resistance, immune paralysis, drug
residues and so on in modem intensive and large-scale farming, and found a new way
for healthy farming.
Selenium-enriched probiotics is a new type of feed additive that converts
inorganic selenium into organic selenium with probiotics, in which the content of
organic selenium exceeds 90% and the content of selenomethionine exceeds 75%.
When used as an additive, it can improve the absorption and utilization rate of
selenium, increase the activities of glutathione peroxidase (GSH-Px) and superoxide
dismutase (SOD) in blood, decrease the activity of malondialdehyde (MDA), increase
the selenium content and antioxidant capacity in body tissues, significantly improve
the production performance of animals, and enhance the immune function and disease
resistance of animals.
Probiotics can activate the immune function and enhance the body's resistance.
Probiotics can stimulate the body to produce specific antibodies; Bacillus can
accelerate the development of intestinal related lymphoid tissue, accelerate the
maturity of immune system, increase the number of T lymphocytes and B
lymphocytes, and improve the humoral immunity and cellular immunity of animals
Thereby enhancing the disease resistance of the organism. It can consume oxygen and
produce acid to inhibit the growth of aerobic pathogenic bacteria and maintain the
balance of intestinal flora.
To solve the above problems, the present invention provides a traditional
Chinese veterinary drug rich in selenium probiotics for enhancing chicken resistance
and a preparation method thereof, which not only has the functions of enriching
blood, nourishing liver and kidney, clearing away heat and toxic materials, regulating
intestines and stomach, preventing and treating diseases, improving the internal
environment of the organism, promoting chicken growth and the like. It can also solve the problems of chicken resistance decline, immune paralysis, microbial drug resistance, drugs and heavy metal residues in modem culture.
In order to achieve the above purpose, the technical scheme adopted by the
invention is as follows:
A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is prepared from the following raw materials in parts
by weight:
16-40 parts of Radix Astragali seu Hedysari, 16-40 parts of Fructus Crataegi,
16-40 parts of Radix Morindae Officinalis, 12-30 parts of Radix Codonopsis, 12-30
parts of Poria, 12-30 parts of Radix Glycyrrhizae, 12-20 parts of Radix et Caulis
Acanthopanacis Senticosi, 12-30 parts of Cortex Eucommiae, 12-30 parts of Herba
Epimedii, 12-30 parts of FructusLigustri Lucidi, 12-30 parts of Radix Isatidis, 12-30
parts of Bulbus Bulbus Fritillaria,12-30 parts of Herba Taraxaci, 8-20 parts of Radix
Polygoni Multiflori, 8-20 parts of Rhizoma Coptidis, 8-20 parts of Cyrtomium
Rhizome, 9-27 parts of yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis.
When the traditional Chinese veterinary drug containing selenium-enriched
probiotics for enhancing chicken resistance is used, the basic daily ration which is 5
times, 10 times and 84 times of the mass of the feed additive is added by stages and
then stirred evenly step by step.
The invention also provides a preparation method of the traditional Chinese
veterinary drug containing selenium-enriched probiotics for enhancing chicken resistance, which comprises the following steps: The technological conditions of wine frying are as follows:
Step 1: Weighing all raw materials according to the formulation;
Step 2: Coarsely crushing the weighed traditional Chinese medicines, and then
parching with wine (using 45C liquor, spraying and soaking the traditional Chinese
medicines according to the volume-mass ratio of liquor to traditional Chinese
medicines of 150ml/kg, and then parching with warm fire at 60°C for 15-20 minutes);
Then stir-fry with ginger juice (mixing ginger and water according to the
mass-volume ratio of 1/2.5, boiling for 15 minutes, filtering, taking 100ml of ginger
juice, spraying 1kg of traditional Chinese medicine, and then stir-frying for 10
minutes at 60°C with warm fire); Finally, drying at 50-60°C until the water content is
less than 7%, crushing, sieving with a 60-mesh sieve, adding 100 parts of weighed
Bacillus subtilis, yeast selenium and starch, and uniformly mixing.
Radix Astragali seu Hedysari selected in the invention has the functions of
supporting poison, expelling pus, promoting diuresis and relieving swelling. Modern
studies have found that Radix Astragali seu Hedysari polysaccharides can increase the
number of stem cells in lymphatic system and bone marrow, and promote the
transformation of these stem cells into active immune cells Promote antibody
production and differentiation and maturation of T lymphocytes; It can improve the
activity of phagocytes and natural killer cells. Astragaloside can improve the
contraction and relaxation of myocardium, protect liver cells from damage, and has
the effects of strengthening heart and protecting liver.
Radix Codonopsis, Poria, Fructus Crataegiand Radix Glycyrrhizae selected in
the invention have the functions of invigorating spleen and stomach, tonifying
middle-warmer, benefiting qi, regulating qi and eliminating dampness, resolving food
stagnation and promoting digestion. The modern pharmacological research of Radix
Codonopsis shows that Radix Codonopsis polysaccharide can activate the active
immunity of the body, enhance the phagocytosis of macrophages and the killing
activity of NK cells, promote the proliferation of splenic lymphocytes and the
increase of endogenous splenic nodules, and have a strong promoting effect on
humoral immunity. Modern pharmacological studies of Poria show that pachyman
and triterpenoids can promote phagocytosis index of macrophages, increase killer cell
activity, increase the content of immune factors, increase the weight of thymus and
spleen, promote lymphocyte proliferation and enhance immunity. Modern
pharmacological studies of Fructus Crataegi show that Fructus Crataegi flavonoids
can dilate coronary artery, improve heart vitality, promote digestive enzyme secretion
and enhance enzyme activity, and the lipase contained in Fructus Crataegiflavonoids
can directly help digestion of fat, enhance the activities of lipase and protease, and
promote metabolism of organism. Modern pharmacological studies of Radix
Glycyrrhizae show that Radix Glycyrrhizae polysaccharide can stimulate the
proliferation of T and B lymphocytes to enhance resistance, activate endothelial
system, induce immunoglobulin production, and induce interferon to enhance the
ability of killing cells.
The Radix Polygoni Multiflori Thunb selected in the invention has the functions
of enriching blood, nourishing heart, nourishing liver and kidney, relaxing bowels and
the like. Modern pharmacological studies show that Radix Polygoni Multiflori Thunb
can delay thymus atrophy, increase thymus weight, increase the number of spleen
plaque forming cells, and significantly enhance the proliferation of thymus and T
lymphocytes induced by concanavalin A.
The Radix Morindae Officinalis, Herba Epimedii, Fructus Ligustri Lucidi,
Cortex Eucommiae. and Radix et Caulis Acanthopanacis Senticosi selected in the
invention have the functions of warming kidney, nourishing liver and kidney,
strengthening tendons and bones, etc. Modern pharmacological studies of Radix
Morindae Officinalis show that it can increase body weight, increase white blood
cells, inhibit thymus atrophy, and has corticosteroid-like and estrogen-like effects.
Modern pharmacological studies of Herba Epimedii have shown that Herba Epimedii
can promote cardiovascular and cerebrovascular blood flow and enhance
hematopoiesis and immunity. Herba Epimedii flavonoids and polysaccharides can
significantly enhance phagocytosis of macrophages, obviously enhance the regulatory
function of neuroendocrine network, maintain the balance of internal environment,
influence the proliferation, differentiation and mineralization of osteoblasts and
promote bone formation. Their gonad enhancement functions are similar to those of
androgen. Modern pharmacological studies of Fructus Ligustri Lucidi show that
oleanolic acid contained in Fructus Ligustri Lucidi has the functions of resisting liver
injury and promoting liver cell regeneration, enhancing the phagocytosis of peripheral leukocytes and reticuloendothelial system, enhancing the activity of cell surface receptors and enhancing cell activity, and has androgenic substances and bidirectional regulation. Modem pharmacological research of Cortex Eucommiae. shows that it can resist immunosuppression, regulate immune balance, enhance cellular immunity and phagocytosis of reticuloendothelial system, activate phagocytosis of mononuclear macrophage system, and increase the content of CAMP in blood to promote growth.
The modem pharmacological research of Radix et Caulis Acanthopanacis Senticosi
shows that it can enhance the nonspecific resistance of the body, and enhance the
body's resistance to physical, chemical, biological and other harmful stimulating
factors. Radix et Caulis Acanthopanacis Senticosi polysaccharide can obviously
improve the ability of cells to produce interferon, has a good effect on the function
reconstruction of B cells, and can enhance the phagocytosis of reticuloendothelial
cells.
Rhizoma Coptidis, Radix Isatidis, Bulbus Bulbus Fritillaria,Herba Taraxaci and
Cyrtomium Rhizome selected in the invention have the functions of clearing away heat
and toxic materials, killing insects, cooling blood and the like. The modern
pharmacological studies of Coptis have shown that Rhizoma Coptidis has good
curative effect on dysentery bacillus, diphtheria, empyema and intestinal ulcer, has the
functions of resisting Brucella and inhibiting Mycobacterium tuberculosis, has
broad-spectrum antibacterial and bacteriostatic effects, and is effective on heart
failure and arrhythmia. The lectin in Radix Isatidis can effectively inhibit hepatitis
virus, influenza A, influenza B, encephalitis B virus and mumps virus. Polysaccharide from Radix Isatidis can promote specific and non-specific humoral and cellular immunity, and tryptamine, an indole derivative of Radix Isatidis, can inhibit bacteria.
Modern pharmacological research of Bulbus Bulbus Fritillaria shows that it has
atropine-like effect to relax smooth muscle and reduce cough; It can relax bronchial
smooth muscle and relieve asthma, inhibit cough center and relieve cough, and
Fritillarine has certain antibacterial effect. Modern pharmacological studies of Herba
Taraxaci show that it can activate sex hormones centered on the pituitary gland in the
hypothalamus, inhibit gram-positive bacteria and gram-negative bacteria, and protect
gastric mucosa. Herba Taraxaci polysaccharide can significantly improve spleen and
thymus index and enhance immune function. Modern pharmacological studies of
Guanzhong show that phloroglucinol compounds have antibacterial and antiviral
effects, and have remarkable antiviral effects on various influenza viruses,
adenovirus, poliovirus, Japanese encephalitis virus and herpes simplex virus, and have
anthelmintic effects, which are similar to estrogen-like effects on thickening uterus.
The Bacillus subtilis selected in the invention consumes oxygen to produce acid,
adjusts the balance of intestinal flora, inhibits the reproduction of Escherichia coli and
Salmonella, and prevents diarrhea of livestock and poultry; It can secrete amylase,
protease and lipase to degrade complex organic matter in feed and improve feed
digestibility; It can produce vitamins, growth-promoting factors and protein
polypeptides to participate in the metabolism of the body, promote the absorption of
calcium and phosphorus, and reduce the emission of harmful gases; It can stimulate the growth of immune organs, activate lymphocytes, improve antibody level, activate immune organs through lymphatic circulation and enhance disease resistance.
The Bacillus subtilis selected in the invention consumes oxygen to produce acid,
adjusts the balance of intestinal flora, inhibits the reproduction of Escherichia coli and
Salmonella, and prevents diarrhea of livestock and poultry; It can secrete amylase,
protease and lipase to degrade complex organic matter in feed and improve feed
digestibility; It can produce vitamins, growth-promoting factors and protein
polypeptides to participate in the metabolism of the body, promote the absorption of
calcium and phosphorus, and reduce the emission of harmful gases; It can stimulate
the growth of immune organs, activate lymphocytes, improve antibody level, activate
immune organs through lymphatic circulation and enhance disease resistance.
Organic selenium contained in the yeast selenium selected in the invention is
beneficial to the absorption and utilization of organisms, and obviously improves the
selenium content of organism tissues. The main function is to improve the activity of
glutathione peroxidase in blood, significantly improve the antioxidant capacity and
enhance the body's resistance; Improve the reproductive performance of poultry,
improve sperm motility, density and quantity, reduce abnormal sperm rate and
improve hatching rate of eggs; It can eliminate the accumulation of heavy metal
elements in the body and relieve the poisoning of heavy metal elements.
The invention has the following beneficial effects:
The traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance mainly starts from spleen, liver and kidney, and makes the digestive system, endocrine system, immune system, hematopoietic system and other functions of livestock and poultry perfect and active by nourishing the spleen, nourishing the liver and nourishing blood and warming the kidney, so as to enhance the body resistance and promote healthy growth.
The traditional Chinese veterinary medicine containing selenium-enriched
probiotics for enhancing chicken resistance mainly achieves the purpose of preventing
diseases before they occur through prevention and treatment methods such as clearing
away heat and toxic materials.
According to the traditional Chinese veterinary drug containing
selenium-enriched probiotics for enhancing chicken resistance, traditional Chinese
medicines such as Herba Epimedii, Morinda officinalis, Fructus Ligustri Lucidi,
Herba Taraxaci and Cyrtomium Rhizome with phytoestrogen and gonadotropin-like
effects are selected, and the physiological activities of chickens are activated through
physiological actions similar to androgens and gonadotropins-like substances, so that
the kidney of chickens is enhanced, and the body resistance is improved and the
growth is promoted.
According to the traditional Chinese veterinary medicine containing
selenium-enriched probiotics for enhancing chicken resistance, the processing method
of the traditional Chinese veterinary medicine can promote the precipitation of
effective components easily soluble in ethanol in the medicine and increase the
curative effect, and the wine processing can alleviate the medicinal properties of cold
and cold medicines, and lead the medicines into blood and efficacy.
According to the traditional Chinese veterinary medicine containing
selenium-enriched probiotics for enhancing chicken resistance, the processing method
of the traditional Chinese veterinary medicine is processed with ginger, which can
alleviate the medicinal properties, modulate the medicinal taste, enhance the warming
and dispersing power, introduce medicines into the spleen, enhance the tonifying
effect of medicines on spleen digestion and immune function, and achieve the
modulation effect of warming spleen and warming stomach.
The traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance can obviously enhance the body resistance of
livestock and poultry, reduce the use of antibiotics, reduce drug residues, and find a
solution for disease prevention in non-resistant culture and green and healthy farming.
In order to make the purpose and advantages of the present invention clearer, the
present invention will be further explained in detail with examples below. It should be
understood that the specific embodiments described herein are only used to explain
the present invention, and are not used to limit the present invention.
In the following examples, yeast selenium was purchased from Angel Yeast Co.,
Ltd., and Bacillus subtilis was purchased from Chongqing Zhengtong Biotechnology
Co., Ltd..
A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is prepared by the following steps:
Step 1: Weighing 16 parts of Radix Astragali seu Hedysari, 16 parts of Fructus
Crataegi, 16 parts of Radix Morindae Officinalis, 12 parts of Radix Codonopsis, 12
parts of Poria, 12 parts of Radix Glycyrrhizae, 12 parts of Radix et Caulis
Acanthopanacis Senticosi, 12 parts of Cortex Eucommiae and 12 parts of Herba
Epimedii, 12 parts of Fructus Ligustri Lucidi, 12 parts of Radix Isatidis, 12 parts of
Bulbus Bulbus Fritillaria, 12 parts of Herba Taraxaci, 8 parts of Radix Polygoni
Multiflori, 8 parts of Coptidis Rhizoma, 8 parts of Cyrtomium Rhizome, 9 parts of
yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis;
Step 2: Coarsely crushing the weighed traditional Chinese medicines in S1, and
then parching with wine (using 45C liquor, spraying and soaking the traditional
Chinese medicines according to the volume-mass ratio of liquor to traditional Chinese
medicines of 150ml/kg, and then parching with warm fire at 60°C for 15-20 minutes);
Then stir-fry with ginger juice (mixing ginger and water according to the
mass-volume ratio of 1/2.5, boiling for 15 minutes, filtering, taking 100ml of ginger
juice, spraying 1kg of traditional Chinese medicine, and then stir-frying for 10
minutes at 60°C with warm fire); Finally, drying at 50-60°C until the water content is
less than 7%, crushing and sieving with a 60-mesh sieve, adding 100 parts of weighed
yeast selenium, Bacillus subtilis and starch, and uniformly mixing to obtain the
medicine.
Example 2
A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is prepared by the following steps:
Step 1: Weighing 32 parts of Radix Astragali seu Hedysari, 32 parts of Fructus
Crataegi, 32 parts of Radix Morindae Officinalis, 24 parts of Radix Codonopsis, 24
parts of Poria, 24 parts of Radix Glycyrrhizae, 24 parts of Radix et Caulis
Acanthopanacis Senticosi, 24 parts of Cortex Eucommiae, 24 parts of Herba
Epimedii, 24 parts of Fructus Ligustri Lucidi, 24 parts of Radix Isatidis, 24 parts of
Bulbus Bulbus Fritillaria,24 parts of Herba Taraxaci, 16 parts of Radix Polygoni
Multiflori, 16 parts of Rhizoma Coptidis, 16 parts of Cyrtomium Rhizome, 18 parts of
yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis;
Step 2: Coarsely crushing the weighed traditional Chinese medicines in SI, and
then parching with wine (using 45C liquor, spraying and soaking the traditional
Chinese medicines according to the volume-mass ratio of liquor to traditional Chinese
medicines of 150ml/kg, and then parching with warm fire at 60°C for 15-20 minutes);
Then stir-fry with ginger juice (mixing ginger and water according to the
mass-volume ratio of 1/2.5, boiling for 15 minutes, filtering, taking 100ml of ginger
juice, spraying 1kg of traditional Chinese medicine, and then stir-frying for 10
minutes at 60°C with warm fire); Finally, drying at 50-60°C until the water content is
less than 7%, crushing and sieving with a 60-mesh sieve, adding 100 parts of weighed
yeast selenium, Bacillus subtilis and starch, and uniformly mixing to obtain the
medicine.
Example 3
A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is prepared by the following steps:
Step 1: Weighing 40 parts of Radix Astragali seu Hedysari, 40 parts of Fructus
Crataegi, 40 parts of Radix Morindae Officinalis, 30 parts of Radix Codonopsis, 30
parts of Poria, 30 parts of Radix Glycyrrhizae, 30 parts of Radix et Caulis
Acanthopanacis Senticosi, 30 parts of Cortex Eucommiae and 30 parts of Herba
Epimedii, 30 parts of Fructus Ligustri Lucidi, 30 parts of Radix Isatidis, 30 parts of
Bulbus Bulbus Fritillaria,30 parts of Herba Taraxaci, 20 parts of Radix Polygoni
Multiflori, 20 parts of Rhizoma Coptidis, 20 parts of Cyrtomium Rhizome, 27 parts of
yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis;
Step 2: Coarsely crushing the weighed traditional Chinese medicines in SI, and
then parching with wine (using 45C liquor, spraying and soaking the traditional
Chinese medicines according to the volume-mass ratio of liquor to traditional Chinese
medicines of 150ml/kg, and then parching with warm fire at 60°C for 15-20 minutes);
Then stir-fry with ginger juice (mixing ginger and water according to the
mass-volume ratio of 1/2.5, boiling for 15 minutes, filtering, taking 100ml of ginger
juice, spraying 1kg of traditional Chinese medicine, and then stir-frying for 10
minutes at 60°C with warm fire); Finally, drying at 50-60°C until the water content is
less than 7%, crushing and sieving with a 60-mesh sieve, adding 100 parts of weighed
yeast selenium, Bacillus subtilis and starch, and uniformly mixing to obtain the
medicine.
In May, 2018, 80 chickens aged 30 days were randomly selected from a
self-employed chicken farm and divided into four groups (three experimental groups
and one blank group). The experimental group was fed with a traditional Chinese veterinary drug for enhancing chicken resistance and selenium-enriched probiotics feed additive for 45 days, while the blank group was fed with basic daily feed, fed with 20-day immunization with new branch vaccine and 25-day immunization with new poultry vaccine, and 6 chickens in each group were randomly sampled after feeding for 45 days. Blood samples were collected and serum immunoglobulin IgG content was detected, and the average values were 627.26ug/kg (measured values ranged from 559.82 to 718.69ug/kg), 673.43ug/kg (measured values ranged from
607.34 to 745.85ug/kg) and 742.46ug/kg (691.53 to 891.53), respectively Compared
with the blank group, the three experimental groups significantly increased the
content of immunoglobulin IgG and enhanced the chicken's resistance.
Example 4
A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is prepared by the following steps:
Step 1: Weighing 16 parts of Radix Astragali seu Hedysari, 16 parts of Fructus
Crataegi, 16 parts of Radix Morindae Officinalis, 12 parts of Radix Codonopsis, 12
parts of Poria, 12 parts of Radix Glycyrrhizae, 12 parts of Radix et Caulis
Acanthopanacis Senticosi, 12 parts of Cortex Eucommiae and 12 parts of Herba
Epimedii, 12 parts of Fructus Ligustri Lucidi, 12 parts of Radix Isatidis, 12 parts of
Bulbus Bulbus Fritillaria, 12 parts of Herba Taraxaci, 8 parts of Radix Polygoni
Multiflori, 8 parts of Coptidis Rhizoma, 8 parts of Cyrtomium Rhizome, 9 parts of
yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis;
Step 2: Coarsely crushing the weighed traditional Chinese medicines in S1, and
then parching with wine (using 45C liquor, spraying and soaking the traditional
Chinese medicines according to the volume-mass ratio of liquor to traditional Chinese
medicines of 150ml/kg, and then parching with warm fire at 60°C for 15-20 minutes);
Then stir-fry with ginger juice (mixing ginger and water according to the
mass-volume ratio of 1/2.5, boiling for 15 minutes, filtering, taking 100ml of ginger
juice, spraying 1kg of traditional Chinese medicine, and then stir-frying for 10
minutes at 60°C with warm fire); Finally, drying at 50-60°C until the water content is
less than 7%, crushing and sieving with a 60-mesh sieve, adding 100 parts of weighed
yeast selenium, Bacillus subtilis and starch, and uniformly mixing to obtain the
medicine.
Example 5
A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is prepared by the following steps:
Step 1: Weighing 32 parts of Radix Astragali seu Hedysari, 32 parts of Fructus
Crataegi, 32 parts of Radix Morindae Officinalis, 24 parts of Radix Codonopsis, 24
parts of Poria, 24 parts of Radix Glycyrrhizae, 24 parts of Radix et Caulis
Acanthopanacis Senticosi, 24 parts of Cortex Eucommiae, 24 parts of Herba
Epimedii, 24 parts of Fructus Ligustri Lucidi, 24 parts of Radix Isatidis, 24 parts of
Bulbus Bulbus Fritillaria,24 parts of Herba Taraxaci, 16 parts of Radix Polygoni
Multiflori, 16 parts of Rhizoma Coptidis, 16 parts of Cyrtomium Rhizome, 18 parts of
yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis;
Step 2: Coarsely crushing the weighed traditional Chinese medicines in S1, and
then parching with wine (using 45C liquor, spraying and soaking the traditional
Chinese medicines according to the volume-mass ratio of liquor to traditional Chinese
medicines of 150ml/kg, and then parching with warm fire at 60°C for 15-20 minutes);
Then stir-fry with ginger juice (mixing ginger and water according to the
mass-volume ratio of 1/2.5, boiling for 15 minutes, filtering, taking 100ml of ginger
juice, spraying 1kg of traditional Chinese medicine, and then stir-frying for 10
minutes at 60°C with warm fire); Finally, drying at 50-60°C until the water content is
less than 7%, crushing and sieving with a 60-mesh sieve, adding 100 parts of weighed
yeast selenium, Bacillus subtilis and starch, and uniformly mixing to obtain the
medicine.
Example 6
A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is prepared by the following steps:
Step 1: Weighing 40 parts of Radix Astragali seu Hedysari, 40 parts of Fructus
Crataegi, 40 parts of Radix Morindae Officinalis, 30 parts of Radix Codonopsis, 30
parts of Poria, 30 parts of Radix Glycyrrhizae, 30 parts of Radix et Caulis
Acanthopanacis Senticosi, 30 parts of Cortex Eucommiae and 30 parts of Herba
Epimedii, 30 parts of Fructus Ligustri Lucidi, 30 parts of Radix Isatidis, 30 parts of
Bulbus Bulbus Fritillaria,30 parts of Herba Taraxaci, 20 parts of Radix Polygoni
Multiflori, 20 parts of Rhizoma Coptidis, 20 parts of Cyrtomium Rhizome, 27 parts of
yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis;
Step 2: Coarsely crushing the weighed traditional Chinese medicines in SI, and
then parching with wine (using 45C liquor, spraying and soaking the traditional
Chinese medicines according to the volume-mass ratio of liquor to traditional Chinese
medicines of 150ml/kg, and then parching with warm fire at 60°C for 15-20 minutes);
Then stir-fry with ginger juice (mixing ginger and water according to the
mass-volume ratio of 1/2.5, boiling for 15 minutes, filtering, taking 100ml of ginger
juice, spraying 1kg of traditional Chinese medicine, and then stir-frying for 10
minutes at 60°C with warm fire); Finally, drying at 50-60°C until the water content is
less than 7%, crushing and sieving with a 60-mesh sieve, adding 100 parts of weighed
yeast selenium, Bacillus subtilis and starch, and uniformly mixing to obtain the
medicine.
In August, 2018, 80 chickens aged 30 days were randomly selected from a
self-employed chicken farm and divided into 4 groups (3 experimental groups and 1
blank group). The experimental group was fed with a Chinese veterinary drug for
enhancing chicken resistance and selenium-enriched probiotics feed additive for 60
days, while the blank group was fed with basic daily feed. Six rabbits in each group
were randomly sampled after feeding for 30 days to immunize the new branch
vaccine and 35 days to immunize the new poultry vaccine, and blood samples were
collected to detect the serum immunoglobulin IgG content. The average values of the
experimental group were 597.39ug/kg (measured value range 533.16-684.47ug/kg)
and 655.64ug/kg (measured value range 617.63-715), respectively.
798.73ug/kg(705.73-867.26ug/kg) and 417.5ug/kg (401.36-460.lug/kg) in the blank group. Compared with the control group, the three experimental groups significantly increased the content of immunoglobulin IgG and enhanced the chicken body resistance. And with the extension of feeding time and the increase of dosage of the traditional Chinese veterinary drug feed additive containing selenium-enriched probiotics for enhancing chicken resistance, the content of serum antibody IgG after chicken immunization increases step by step, which is significantly higher than that of the control group, thus enhancing the chicken's resistance.
The above are only the preferred embodiments of the present invention, and it
should be pointed out that for ordinary people in the technical field, without departing
from the principle of the present invention, several improvements and embellishments
can be made, and these improvements and embellishments should also be regarded as
the protection scope of the present invention.
Claims (5)
1. A traditional Chinese veterinary drug containing selenium-enriched probiotics
for enhancing chicken resistance is characterized by comprising the following raw
materials in parts by weight:
16-40 parts of Radix Astragali seu Hedysari, 16-40 parts of Fructus Crataegi,
16-40 parts of Radix Morindae Officinalis, 12-30 parts of Radix Codonopsis, 12-30
parts of Poria, 12-30 parts of Radix Glycyrrhizae, 12-20 parts of Radix et Caulis
Acanthopanacis Senticosi, 12-30 parts of Cortex Eucommiae, 12-30 parts of Herba
Epimedii, 12-30 parts of Fructus LigustriLucidi, 12-30 parts of Radix Isatidis, 12-30
parts of Bulbus Bulbus Fritillaria,12-30 parts of Herba Taraxaci, 8-20 parts of Radix
Polygoni Multiflori, 8-20 parts of Rhizoma Coptidis, 8-20 parts of Cyrtomium
Rhizome, 9-27 parts of yeast selenium of 2000mg/kg and 40 parts of Bacillus subtilis.
2. The traditional Chinese veterinary drug containing selenium-enriched
probiotics for enhancing chicken resistance according to claim 1 is characterized in
that: when in use, basic diets which are 5 times, 10 times and 84 times the mass of
feed additives are added by stages, and then stirred evenly step by step.
3. A formulation of the traditional Chinese veterinary drug containing
selenium-enriched probiotics for enhancing chicken resistance is characterized by
comprising the following steps:
Step 1: Weighing all raw materials according to the formulation;
Step 2: Coarsely crushing the weighed traditional Chinese medicines, and then
parching with wine, then stir-fry with ginger juice; finally, drying at 50-60°C until the water content is less than 7%, crushing, sieving with a 60-mesh sieve, adding 100 parts of weighed Bacillus subtilis, yeast selenium and starch, and uniformly mixing.
4. The preparation method of a traditional Chinese veterinary drug containing
selenium-enriched probiotics for enhancing chicken resistance according to claim 3 is
characterized in that the technological conditions of wine frying are as follows: using
°C liquor, spraying and soaking the traditional Chinese medicines according to the
volume-mass ratio of liquor to traditional Chinese medicines of 150ml/kg, and then
parching with warm fire at 60°C for 15-20 minutes.
5. The preparation method of a traditional Chinese veterinary drug containing
selenium-enriched probiotics for enhancing chicken resistance according to claim 3 is
characterized in that the technological conditions for frying ginger juice are as
follows: mixing ginger and water according to the mass-volume ratio of 1/2.5, boiling
for 15 minutes, filtering, taking 100 ml of ginger juice, spraying 1 kg of traditional
Chinese medicine, and then stir-frying for 10 minutes at 60°C with warm fire.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2021104815A AU2021104815A4 (en) | 2021-08-02 | 2021-08-02 | Traditional Chinese Veterinary Medicine Containing Selenium-enriched Probiotics for Enhancing Chicken Resistance and Formulation Thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2021104815A AU2021104815A4 (en) | 2021-08-02 | 2021-08-02 | Traditional Chinese Veterinary Medicine Containing Selenium-enriched Probiotics for Enhancing Chicken Resistance and Formulation Thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2021104815A4 true AU2021104815A4 (en) | 2021-09-30 |
Family
ID=77857845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2021104815A Active AU2021104815A4 (en) | 2021-08-02 | 2021-08-02 | Traditional Chinese Veterinary Medicine Containing Selenium-enriched Probiotics for Enhancing Chicken Resistance and Formulation Thereof |
Country Status (1)
| Country | Link |
|---|---|
| AU (1) | AU2021104815A4 (en) |
-
2021
- 2021-08-02 AU AU2021104815A patent/AU2021104815A4/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102823779A (en) | Dairy cow feed, preparation method and Chinese medicine for improving dairy cow production performance | |
| CN103478496A (en) | Urinary tract health maintenance nutritional health-care food for dogs and cats and preparation method of food | |
| CN109527260B (en) | Compound bioactive feed additive for poultry and preparation method thereof | |
| CN112568324A (en) | Composite probiotic fermented traditional Chinese medicine feed additive and preparation method and application thereof | |
| CN107581396A (en) | A kind of egg feedstuff for improving laying hen egg yield and preparation method thereof | |
| KR101139372B1 (en) | Method for preparing feed additive and feed additivethere from | |
| TW391878B (en) | Pharmaceutical composition or feedstuff comprising at least one of rosa roxburghii, artemisiae argyi folium and brassica oleracea var. capitata l. | |
| Long et al. | Dietary supplementation with Forsythia suspensa extract during late gestation improves reproductive performance, colostrum composition, antioxidant status, immunoglobulin, and inflammatory cytokines in sows and newborn piglets | |
| CN109497310A (en) | One boar combines Se-enriched feedstuff with Chinese herbal medicine | |
| AU2021104815A4 (en) | Traditional Chinese Veterinary Medicine Containing Selenium-enriched Probiotics for Enhancing Chicken Resistance and Formulation Thereof | |
| CN101194995B (en) | Proprietary Chinese medicine for treating animal virus, bacterium and mix infection | |
| CN106804904A (en) | A kind of cow feed additive of Chinese herbal medicine | |
| CN110089619A (en) | A kind of Chinese medicine bacteria preparation fermented feed and preparation method thereof | |
| CN109984255B (en) | Antitoxic immunopotentiating peptide compound microbial feed additive and preparation method thereof | |
| CN107691301A (en) | A kind of method of fish fast-growth | |
| CN107114599A (en) | Chinese medicine broiler fodder and preparation method thereof | |
| CN114470084A (en) | Environment-friendly and efficient composition for preventing and treating white feces of tilapia mossambica as well as preparation method and application thereof | |
| CN107751558A (en) | A kind of Chinese medicine preparation and preparation method of anti-milking sow heat stress increase lactation amount | |
| CN112617005A (en) | Chicken feed additive, preparation method and application thereof, and chicken feed | |
| CN110973377A (en) | Additive for improving beef cattle fattening efficiency | |
| CN104606627B (en) | A kind of pharmaceutical composition for treating grice diarrhoea and preparation method thereof | |
| CN108938781A (en) | A kind of herbal medicine and preparation method thereof of the enhancing chicken resistance containing selenium-enriched probiotics | |
| CN111759988B (en) | Traditional Chinese medicine preparation for improving immunity of weaned piglets and preparation method | |
| CN116251135B (en) | Composition for preventing and treating swine high fever and application method | |
| CN116808109B (en) | Traditional Chinese medicine compound for resisting chronic heat stress of broiler chickens and preparation and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGI | Letters patent sealed or granted (innovation patent) |