AU2018332212B2 - Topical formulations of chloroprocaine - Google Patents

Topical formulations of chloroprocaine Download PDF

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Publication number
AU2018332212B2
AU2018332212B2 AU2018332212A AU2018332212A AU2018332212B2 AU 2018332212 B2 AU2018332212 B2 AU 2018332212B2 AU 2018332212 A AU2018332212 A AU 2018332212A AU 2018332212 A AU2018332212 A AU 2018332212A AU 2018332212 B2 AU2018332212 B2 AU 2018332212B2
Authority
AU
Australia
Prior art keywords
formulation
chloroprocaine
anesthesia
weight
hydroxyethyl cellulose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2018332212A
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English (en)
Other versions
AU2018332212A1 (en
Inventor
Clara BIANCHI
Elisabetta Donati
Augusto Mitidieri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sintetica SA
Original Assignee
Sintetica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sintetica SA filed Critical Sintetica SA
Publication of AU2018332212A1 publication Critical patent/AU2018332212A1/en
Application granted granted Critical
Publication of AU2018332212B2 publication Critical patent/AU2018332212B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2018332212A 2017-09-15 2018-09-14 Topical formulations of chloroprocaine Active AU2018332212B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762559220P 2017-09-15 2017-09-15
US62/559,220 2017-09-15
PCT/IB2018/057073 WO2019053657A1 (en) 2017-09-15 2018-09-14 TOPICAL FORMULATIONS OF CHLOROPROCAINE

Publications (2)

Publication Number Publication Date
AU2018332212A1 AU2018332212A1 (en) 2020-02-27
AU2018332212B2 true AU2018332212B2 (en) 2023-03-16

Family

ID=63713967

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018332212A Active AU2018332212B2 (en) 2017-09-15 2018-09-14 Topical formulations of chloroprocaine

Country Status (22)

Country Link
US (3) US10792271B2 (https=)
EP (1) EP3681473A1 (https=)
JP (1) JP2020533321A (https=)
KR (1) KR102759903B1 (https=)
CN (1) CN111163756B (https=)
AU (1) AU2018332212B2 (https=)
CA (1) CA3070336C (https=)
CL (1) CL2020000665A1 (https=)
CO (1) CO2020002985A2 (https=)
CR (1) CR20200133A (https=)
CU (1) CU20200019A7 (https=)
EA (1) EA202090735A1 (https=)
EC (1) ECSP20022313A (https=)
IL (1) IL273213B2 (https=)
JO (1) JOP20200010A1 (https=)
MA (1) MA50241A (https=)
MX (1) MX2020002898A (https=)
PE (1) PE20201281A1 (https=)
PH (1) PH12020550029A1 (https=)
SG (1) SG11202000992RA (https=)
WO (1) WO2019053657A1 (https=)
ZA (1) ZA202000601B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202139993A (zh) * 2020-03-16 2021-11-01 瑞士商辛鐵堤卡公司 具有經改良之功能性的眼用氯普魯卡因(chloroprocaine)凝膠

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
US20050137177A1 (en) * 2003-12-18 2005-06-23 Shafer Steven L. Ester combination local anesthetic

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR930000050B1 (ko) * 1990-08-29 1993-01-06 브리스톨-마이어즈 스퀴브 컴페니 항균제 겔 배합물
JP2004123634A (ja) * 2002-10-03 2004-04-22 Lion Corp 眼科用組成物
WO2004058329A2 (en) * 2002-12-20 2004-07-15 The Board Of Trustees Of The Leland Stanford Junior University Ester combination local anesthetic
EA200701131A1 (ru) * 2004-11-24 2007-12-28 Алгоркс Фармасьютикалз, Инк. Гелеобразная препаративная форма капсаициноида и способы её применения
ITMI20051633A1 (it) 2005-09-06 2007-03-07 Sint Sa Nuovo uso di una composizione comprendente cloroprocaina hcl nuova composizione comprendente cloroprocaina hcl e metodo per la sua fabbricazione
ITMI20122120A1 (it) * 2012-12-12 2014-06-13 Sint Sa Composizione farmaceutica a base di cloroprocaina per la somministrazione intratecale ripetuta
CN103405576B (zh) * 2013-08-23 2016-03-30 何学忠 一种治疗由焊接强光辐射引起的眼部疾病的滴眼液

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
US20050137177A1 (en) * 2003-12-18 2005-06-23 Shafer Steven L. Ester combination local anesthetic

Also Published As

Publication number Publication date
EP3681473A1 (en) 2020-07-22
JP2020533321A (ja) 2020-11-19
IL273213B2 (en) 2025-06-01
IL273213B1 (en) 2025-02-01
KR20200053476A (ko) 2020-05-18
AU2018332212A1 (en) 2020-02-27
MX2020002898A (es) 2020-11-06
CA3070336C (en) 2022-08-23
CU20200019A7 (es) 2020-11-30
WO2019053657A1 (en) 2019-03-21
IL273213A (en) 2020-04-30
KR102759903B1 (ko) 2025-01-23
US11969403B2 (en) 2024-04-30
EA202090735A1 (ru) 2020-06-22
US20190083446A1 (en) 2019-03-21
US10792271B2 (en) 2020-10-06
BR112020003095A2 (pt) 2020-08-25
CL2020000665A1 (es) 2020-09-21
SG11202000992RA (en) 2020-03-30
JOP20200010A1 (ar) 2020-01-22
CA3070336A1 (en) 2019-03-21
CN111163756A (zh) 2020-05-15
ZA202000601B (en) 2021-02-24
PH12020550029A1 (en) 2021-02-08
CO2020002985A2 (es) 2020-05-29
ECSP20022313A (es) 2020-07-31
CN111163756B (zh) 2022-04-15
US20200390738A1 (en) 2020-12-17
US20240216323A1 (en) 2024-07-04
MA50241A (fr) 2020-07-22
CR20200133A (es) 2020-05-09
PE20201281A1 (es) 2020-11-24

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