AU2013292378A1 - Rapid measurement of formed blood component sedimentation rate from small sample volumes - Google Patents

Rapid measurement of formed blood component sedimentation rate from small sample volumes

Info

Publication number
AU2013292378A1
AU2013292378A1 AU2013292378A AU2013292378A AU2013292378A1 AU 2013292378 A1 AU2013292378 A1 AU 2013292378A1 AU 2013292378 A AU2013292378 A AU 2013292378A AU 2013292378 A AU2013292378 A AU 2013292378A AU 2013292378 A1 AU2013292378 A1 AU 2013292378A1
Authority
AU
Australia
Prior art keywords
hematocrit
centrifuge
sample
vessel
time
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2013292378A
Other languages
English (en)
Inventor
Samartha ANEKAL
Mark DAYEL
Elizabeth A. Holmes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labrador Diagnostics LLC
Original Assignee
Theranos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theranos Inc filed Critical Theranos Inc
Publication of AU2013292378A1 publication Critical patent/AU2013292378A1/en
Assigned to THERANOS IP COMPANY, LLC reassignment THERANOS IP COMPANY, LLC Request for Assignment Assignors: THERANOS, INC.
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/042Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/30Control equipment
    • B01D21/32Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00Arrangements for image or video recognition or understanding
    • G06V10/10Image acquisition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/011Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/012Red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/042Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • G01N2015/055Investigating sedimentation of particle suspensions in blood for hematocrite determination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Multimedia (AREA)
  • Theoretical Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Centrifugal Separators (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
AU2013292378A 2012-07-18 2013-07-18 Rapid measurement of formed blood component sedimentation rate from small sample volumes Abandoned AU2013292378A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261673037P 2012-07-18 2012-07-18
US61/673,037 2012-07-18
PCT/US2013/051143 WO2014015177A1 (en) 2012-07-18 2013-07-18 Rapid measurement of formed blood component sedimentation rate from small sample volumes

Publications (1)

Publication Number Publication Date
AU2013292378A1 true AU2013292378A1 (en) 2015-01-29

Family

ID=49945429

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013292378A Abandoned AU2013292378A1 (en) 2012-07-18 2013-07-18 Rapid measurement of formed blood component sedimentation rate from small sample volumes

Country Status (13)

Country Link
US (6) US9347867B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP2875351B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (4) JP6336697B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR20150036494A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN110187089B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2013292378A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR112015001239A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2878872A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL236767A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2014DN11202A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX372784B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (2) SG10201605479QA (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2014015177A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101252259B1 (ko) * 2011-12-12 2013-04-08 포항공과대학교 산학협력단 디스크형 미세 유체 시스템 및 혈액 상태 확인 방법
US8984932B2 (en) 2012-07-18 2015-03-24 Theranos, Inc. Rapid measurement of formed blood component sedimentation rate from small sample volumes
SG10201605479QA (en) 2012-07-18 2016-08-30 Theranos Inc Rapid measurement of formed blood component sedimentation rate from small sample volumes
US10591409B2 (en) 2014-02-25 2020-03-17 Theranos Ip Company, Llc Systems, devices, and methods for sample integrity verification
US20150241684A1 (en) 2014-02-25 2015-08-27 Theranos, Inc. Systems, devices, and methods for sample integrity verification
JP6360696B2 (ja) * 2014-03-18 2018-07-18 日本光電工業株式会社 血液検査装置および血液検査方法
CN106573256B (zh) * 2014-07-30 2019-06-14 豪夫迈·罗氏有限公司 用于处理颗粒的自动化系统
CN104458519B (zh) * 2014-12-08 2017-01-18 重庆南方数控设备有限责任公司 获取血沉数据的精确检测方法
CN107407650B (zh) * 2015-03-31 2020-09-11 索尼公司 电特性测量装置、电特性测量方法、血液状况分析系统以及用于计算机化该方法的电特性测量程序
JP6327751B2 (ja) * 2015-10-06 2018-05-23 株式会社セルピック 自動血液分離装置
CN113588501B (zh) * 2015-12-08 2024-12-17 生物马特里卡公司 降低红细胞沉降速率
WO2020170772A1 (ja) * 2019-02-21 2020-08-27 株式会社シンキー 遠心機において使用される検出器及び検出システム
SE545603C2 (en) * 2019-08-22 2023-11-07 Grimaldi Dev Ab Separating particles through centrifugal sedimentation
CN111712703B (zh) * 2019-11-18 2024-04-12 深圳迈瑞生物医疗电子股份有限公司 样本分析仪及样本分析方法
CN112033868B (zh) * 2020-09-01 2025-01-17 湖南伊鸿健康科技有限公司 一种加速细胞沉淀的方法、金属板及显微镜
CN111912753A (zh) * 2020-09-01 2020-11-10 湖南伊鸿健康科技有限公司 一种加速细胞沉淀的方法及装置
CN112034192B (zh) * 2020-09-07 2021-04-13 北京大学第三医院(北京大学第三临床医学院) 一种血沉校正方法
CN112766148A (zh) * 2021-01-18 2021-05-07 河南大学 一种受人类扰动冲积地层沉积韵律的识别方法及系统
TWI774220B (zh) * 2021-01-29 2022-08-11 國泰醫療財團法人國泰綜合醫院 紅血球沈降速率量測方法、血液檢測載體與量測套組
IT202100028064A1 (it) * 2021-11-04 2023-05-04 Arcangelo Ventura Dispositivo per la misura automatica della velocita' di sedimentazione e del volume del fango.
EP4522985A1 (en) * 2022-05-10 2025-03-19 Radiometer Medical ApS Determining an amount of analyte in plasma based on a measurement of an amount of analyte in a whole-blood sample
KR102791324B1 (ko) * 2023-03-22 2025-04-08 부산대학교 산학협력단 딥러닝을 이용한 적혈구 침강 속도 진단 시간 단축 방법 및 이를 위한 시스템
WO2025144706A1 (en) * 2023-12-28 2025-07-03 Idexx Laboratories, Inc. Determination of components in samples
CN119985470B (zh) * 2025-01-14 2025-09-19 中国人民解放军总医院第八医学中心 基于图像检测的血液分离血浆样本的层析效果评估方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL92884C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1953-07-09
US3288019A (en) * 1962-05-08 1966-11-29 Charles M Blumenfeld Photographic type sedimentation recorder
US3848796A (en) * 1971-02-08 1974-11-19 Coulter Electronics A centrifuge apparatus for sedimentation study
US4010893A (en) 1975-06-20 1977-03-08 Becton, Dickinson And Company Triac centrifuge
US4197735A (en) 1978-11-06 1980-04-15 Chase Instruments Corporation Blood sedimentation rate test means
US4558947A (en) 1983-11-07 1985-12-17 Wardlaw Stephen C Method and apparatus for measuring blood constituent counts
US4745279A (en) 1986-01-02 1988-05-17 American Hospital Supply Corporation Hematocrit measuring apparatus
US4848900A (en) 1987-06-22 1989-07-18 Kuo Cheng Deng Computerized automatic monitoring and recording system of erythrocyte sedimentation process
JPH0275959A (ja) * 1988-09-12 1990-03-15 Nittec Co Ltd 自動分折装置
US5003488A (en) * 1989-03-10 1991-03-26 Gespac, Inc. Automatic fluid sedimentation rate measurement apparatus and method
CA2011100C (en) 1989-05-24 1996-06-11 Stephen C. Wardlaw Centrifuged material layer measurements taken in an evacuated tube
US5578269A (en) 1993-06-11 1996-11-26 Ortho Diagnostic Systems Inc. Automated blood analysis system with an integral centrifuge
US5594164A (en) * 1994-07-12 1997-01-14 Bull; Brian S. Method and apparatus for rapid determination of blood sedimentation rate
US6506606B1 (en) * 1995-06-06 2003-01-14 Brigham And Women's Hospital Method and apparatus for determining erythrocyte sedimentation rate and hematocrit
CN2259629Y (zh) * 1995-12-26 1997-08-13 张崇俊 微血量血沉仪
US5914272A (en) * 1996-06-19 1999-06-22 Becton Dickinson And Company Test method for determining the erythrocyte sedimentation rate and a surfactant for use therein
CA2230222A1 (en) * 1997-03-10 1998-09-10 Stephen C. Wardlaw Method and assembly for rapid measurement of cell layers
US20010044584A1 (en) 1997-08-28 2001-11-22 Kensey Kenneth R. In vivo delivery methods and compositions
GB9804560D0 (en) 1998-03-05 1998-04-29 Zynocyte Ltd Method of measuring erthrocyte sedimentation rate (esr),plasma viscosity and plasma fibrinogen of a blood sample
US6517475B1 (en) 1998-09-25 2003-02-11 Baldwin Filters, Inc. Centrifugal filter for removing soot from engine oil
JP2000329779A (ja) * 1999-05-19 2000-11-30 Sefa Technology Kk 沈降速度測定方法およびその装置
US6388740B1 (en) * 1999-06-22 2002-05-14 Robert A. Levine Method and apparatus for timing intermittent illumination of a sample tube positioned on a centrifuge platen and for calibrating a sample tube imaging system
US6204066B1 (en) * 1999-06-25 2001-03-20 Robert A. Levine Rapid method for determining the erythrocyte sedimentation rate in a sample of anticoagulated whole blood
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7207939B2 (en) 2002-10-03 2007-04-24 Coulter International Corp. Apparatus and method for analyzing a liquid in a capillary tube of a hematology instrument
US6974701B2 (en) * 2003-03-21 2005-12-13 Hemovations, Llc Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US7422905B2 (en) * 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
CN1256587C (zh) 2004-05-31 2006-05-17 苏州市第二人民医院 血液流变全血质控物及其制备方法
ITUD20050118A1 (it) * 2005-07-13 2007-01-14 Sire Analytical Systems Srl Procedimento per la taratura di macchine per l' analisi di parametri del sangue connessi alla densita' del sangue, quali la velocita' di eritrosedimentazione e/o di aggregazione dei globuli rossi
CN101501472A (zh) * 2006-08-17 2009-08-05 科安比司特公司 具有鲁棒性自动处理控制的血液处理设备
AU2008200733A1 (en) * 2007-02-16 2008-09-04 Harvest Technologies Corporation Method for adjusting sedimentation rates
US8326008B2 (en) 2008-04-09 2012-12-04 Abbott Point Of Care, Inc. Method for measuring the area of a sample disposed within an analysis chamber
CN105740641A (zh) 2009-10-19 2016-07-06 提拉诺斯公司 集成的健康数据采集和分析系统
US20110226045A1 (en) 2009-11-25 2011-09-22 Mcquillan Adrian Charles Liquid analysis system
CN201773058U (zh) * 2010-01-08 2011-03-23 郭瑞林 一种带负压气囊血沉管
US20110293521A1 (en) * 2010-05-28 2011-12-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Anti-viral compositions and methods for administration
EP2593156B1 (en) 2010-07-15 2015-08-19 Terumo BCT, Inc. Method for optimizing spin time in a centrifuge apparatus for biologic fluids
JP5945282B2 (ja) 2011-01-21 2016-07-05 セラノス, インコーポレイテッド 試料使用の極大化のためのシステム及び方法
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
SG10201605479QA (en) 2012-07-18 2016-08-30 Theranos Inc Rapid measurement of formed blood component sedimentation rate from small sample volumes
US8984932B2 (en) 2012-07-18 2015-03-24 Theranos, Inc. Rapid measurement of formed blood component sedimentation rate from small sample volumes

Also Published As

Publication number Publication date
MX372784B (es) 2020-07-01
US20190170630A1 (en) 2019-06-06
BR112015001239A2 (pt) 2017-07-04
IN2014DN11202A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-10-02
JP2018021936A (ja) 2018-02-08
EP2875351B1 (en) 2022-11-09
US20190226967A1 (en) 2019-07-25
CA2878872A1 (en) 2014-01-23
JP2015528910A (ja) 2015-10-01
EP2875351A4 (en) 2016-06-15
CN104641230A (zh) 2015-05-20
US20150198515A1 (en) 2015-07-16
MX2015000807A (es) 2015-05-07
US20210140866A1 (en) 2021-05-13
SG10201605479QA (en) 2016-08-30
KR20150036494A (ko) 2015-04-07
WO2014015177A1 (en) 2014-01-23
EP2875351A1 (en) 2015-05-27
CN110187089B (zh) 2021-10-29
US9347867B2 (en) 2016-05-24
CN104641230B (zh) 2019-06-28
JP6336697B2 (ja) 2018-06-06
SG11201500349YA (en) 2015-02-27
CN110187089A (zh) 2019-08-30
JP2020012852A (ja) 2020-01-23
HK1210833A1 (en) 2016-05-06
US11320355B2 (en) 2022-05-03
JP2022009402A (ja) 2022-01-14
IL236767A (en) 2017-06-29
US10222310B2 (en) 2019-03-05
US20160341650A1 (en) 2016-11-24
US10018549B2 (en) 2018-07-10
US10788409B2 (en) 2020-09-29
US20140020457A1 (en) 2014-01-23

Similar Documents

Publication Publication Date Title
US11320355B2 (en) Rapid measurement of formed blood component sedimentation rate from small sample volumes
US10012638B2 (en) Rapid measurement of formed blood component sedimentation rate from small sample volumes
JP2022043307A (ja) 少量のサンプル容積から形成された血液構成成分沈降速度の迅速な測定
US20110269614A1 (en) Blood Processing Apparatus with Robust Outflow Process Control
WO2022009104A2 (en) Focusing a microscope using fluorescent images
EP2092293A2 (en) Blood processing apparatus with robust outflow process control
US20200264181A1 (en) Measurement success/failure determination method and sample measurement device
HK1210833B (zh) 快速測量小容量樣本中有形血液成分的沉降率
HK1231958B (zh) 来自小样品体积的成形血液组分沉降速率的快速测量
HK1231958A1 (en) Rapid measurement of formed blood component sedimentation rate from small sample volumes

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: THERANOS IP COMPANY, LLC

Free format text: FORMER APPLICANT(S): THERANOS, INC.

MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted