AU2006312419B2 - Radio frequency ablation electrode for selected tissue removal - Google Patents

Radio frequency ablation electrode for selected tissue removal Download PDF

Info

Publication number
AU2006312419B2
AU2006312419B2 AU2006312419A AU2006312419A AU2006312419B2 AU 2006312419 B2 AU2006312419 B2 AU 2006312419B2 AU 2006312419 A AU2006312419 A AU 2006312419A AU 2006312419 A AU2006312419 A AU 2006312419A AU 2006312419 B2 AU2006312419 B2 AU 2006312419B2
Authority
AU
Australia
Prior art keywords
electrode
radiofrequency
coil spring
electrode tip
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006312419A
Other versions
AU2006312419A1 (en
Inventor
Jung-Hwa Hong
Chang-Mo Hwang
Byung-Jo Kim
Sang-Heon Lee
Kyung Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea University Industry-Academy Collaboration Foundation
U and I Corp
Original Assignee
Korea University Industry-Academy Collaboration Foundation
U and I Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to KR20050106763 priority Critical
Priority to KR10-2005-0106763 priority
Application filed by Korea University Industry-Academy Collaboration Foundation, U and I Corp filed Critical Korea University Industry-Academy Collaboration Foundation
Priority to PCT/KR2006/004683 priority patent/WO2007055521A1/en
Publication of AU2006312419A1 publication Critical patent/AU2006312419A1/en
Application granted granted Critical
Publication of AU2006312419B2 publication Critical patent/AU2006312419B2/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38023465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2006312419(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application status is Ceased legal-status Critical
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434Neural system
    • A61B2018/0044Spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1425Needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1435Spiral

Description

-1 RADIO FREQUENCY ABLATION ELECTRODE FOR SELECTED TISSUE REMOVAL Technical Field The present invention relates to a radiofrequency electrode for ablating tissue. 5 Background Art Generally, if a hernia of the intervertebral discs in the spine occurs, the intervertebral discs in the spine protrude to put pressure on an adjacent nerve, thus causing a lower back pain. The intervertebral discs are composed of a nucleus pulposus 10 (illustrated in Fig. 8) and an annulus fibrosus surrounding the nucleus pulposus 20 10 (illustrated in Fig. 8). If upon applying any physical impact to the intervertebral discs, the inner wall of the annulus fibrosus is torn, a pressure generated from the body weight or excessive impact generated when one stands up for a long period of time, causes the nucleus pulposus in the intervertebral discs to flow out between the torn inner walls of the annulus fibrosus, and a high pressure in the intervertebral discs is transferred to the is skin of the intervertebral discs, whereby a part of the intervertebral discs is protruded. This phenomenon is referred to as a "hernia of the intervertebral discs." The protruded parts of the intervertebral discs do not restore their original states and continuously maintain their protruded forms, whereby pressure is put on the nerve near the spin, thereby leading to a lumbar pain. 20 The hernia of the intervertebral discs can be treated by surgical operation. However, a therapeutic effect cannot be attained in 30% of the surgically operated patients, and further the surgical operation is accompanied by ablation of the spinal nerve region, which causes 5 to 10% of the operated patients to suffer Failed Back Surgery Syndromes (F.B.S.S) for one's lifetime. 25 As an alternative approach for treating the hernia of the intervertebral discs, mention may be made of a restoring method comprising the steps of removing the components of the nucleus pulposus in the intervertebral discs to reduce the internal pressure of the intervertebral discs, which causes the protruded region of intervertebral discs to spontaneously get back to the inside of the intervertebral discs. This approach 30 can be effected not only by a surgical operation, but also by a non-surgical operation, which is a method comprising the steps of inserting a radiofrequency electrode in a tissue in the intervertebral discs, and applying radiofrequency to ablate the tissues around the electrode by the high-energy magnetic field formed using radiofrequency in the gas state where the components of the nucleus pulposus are separated into the 35 negatively charged electrons and the positively charged ions. The method for ablating a tissue by means of a radiofrequency electrode is advantageous in that it can make the hospital stays shorter, significantly lower a surgery cost, and lessen the risk of 2294431_1 (GHMatters) 4/06110 -2 generation of post-surgery side-effects, as compared with the surgical operation method. The radiofrequency is a frequency in the range from 100 to 20,000 kHz, and methods for ablating or removing a body tissue, and removing waste products, etc. in 5 the blood vessel are disclosed in U.S. Patent No. 6,554,827 B2, etc. Fig. 8 is a diagram illustrating the treatment of a hernia of the spinal intervertebral discs using a radiofrequency electrode. As illustrated in Fig. 8, a part of the intervertebral discs in a human body is protruded to put pressure on a nerve root 30, thus causing a waist pain. The skin 40 of the protruded part of the spinal intervertebral 10 discs gets hydrostatic pressure by the internal composition 50 of the protruded part, and the internal composition 50 of the protruded part does not have high fluidity, and thus maintains its protruded form, while continuously putting pressure on the nerve root 30, thereby causing a lumbar pain. Here, by positioning the radiofrequency electrode tip through a catheter 60 in the internal composition 50 in the skin 40 of the protruded part 15 of the spinal intervertebral discs, and then applying radiofrequency, a radiofrequency region is generated around two electrodes, and the tissues in the radiofrequency-applied part 70 around the electrodes are separated into the negatively charged electrons and the positively charged ions, and accordingly, are changed to ones in the neutral gas having a high degree of charge separation, and with a lowered pressure, the protruded part 20 returns to the original state. Conventional radiofrequency electrodes are in the linear form, and thus electrodes are limited in the regions to be approached in a body, since the electrodes reach only the locations arranged in line with the locations in the body to which the electrode is inserted. Particularly, if the hernia of the intervertebral discs is treated, the 25 presence of the spine and spinal nerve sets a limit on the locations to which a radiofrequency electrode tip is inserted. As such, as illustrated in Fig. 8, the tissue regions opposite to the locations to which the radiofrequency electrode is inserted is hard to be ablated. The method using a radiofrequency electrode adopts a principle of restoring the extruded region of the intervertebral discs by a negative pressure generated 30 from ablation of the tissue, and thus it has extremely low efficiency in the case where the tissue around the extruded region cannot be ablated. On the other hand, mention may be made of another method in which a radiofrequency electrode having its ends preliminarily curved at a prescribed curvature prior to be inserted from the outside is guided by a catheter, and then reaches to the 35 parts, which is hard to be linearly approached, by means of a restoring force. In this method, however, the curves of the parts which had once entered a body are restored in a pre-determined fashion. Accordingly, the method has a risk of trials based on a 2294431_1 (GHMatters) 4/06/10 -3 experience or predictions, which gives a limit on use in the wide applications, and further it has a drawback that it is difficult to ablate the tissues using radiofrequency by precisely locating the electrode in the extruded region in the intervertebral discs which varies depending on the individuals. 5 Further, disclosed is a method in which an end of a radiofrequency electrode can be bent with a flexible polymeric material, but this method also has a drawback that it is difficult to precisely locate a radiofrequency electrode tip in the extruded region in the intervertebral discs, and the polymeric material is melted upon discharge of radiofrequency. 10 Summary of the Invention In accordance with the present invention, there is provided a radiofrequency electrode for selective ablation of a body tissue, comprising a first electrode and a second electrode which are inserted into the body tissue, wherein a first electrode tip formed at the end of the first electrode and a is second electrode tip formed at the end of the second electrode are combined with a predetermined gap between them, and wherein a coil spring is bonded to the ends of the first electrode and the second electrode, said coil spring being configured to have its end part bent in the free state and being transformed by pulling either or both of the first electrode and the second 20 electrode. Preferred embodiments of the present invention may be used to locally ablate tissue in a specific region in a body using a radiofrequency (RF), and may employ a radio frequency electrode which is used for easily ablating a tissue in a desired location, by inserting, through a catheter, a radiofrequency electrode tip assembly to a tissue 25 region in a body to be ablated, and then controlling the direction of the electrode by an elastic force of an end part of the radiofrequency electrode. Therefore, the present invention has been made in order to overcome the above-described problems, and thus it is an object of the present invention to provide a radiofrequency electrode for selective ablation of a body tissue, which has a direction 30 controlling function so as to easily locate a radiofrequency electrode tip at a specific region in a body tissue. Paragraphs [ 12] to [23] provide features of preferred embodiments. The first electrode and second electrode can be guided to a body tissue by a catheter. 35 The first electrode comprises a first electrode tip and a first electrode lead, wherein the first electrode lead is connected to the first electrode tip, the first electrode 2294431_1 (GHMatters) 4/06/10 - 3a lead is in the form of a metal wire, and inserted into the coil spring. 2294431_1 (GHMatters) 4106/10 WO 2007/055521 PCT/KR2006/004683 [14] The second electrode comprises a second electrode tip and a second electrode lead, and the second electrode lead is in the form of a coil spring, wherein one end of the coil spring is connected to the second electrode tip. [15] The first electrode tip and the second electrode tip are combined with an electrically insulating material to form an electrode tip assembly. [16] One end of the second electrode tip is inserted into the electrically insulating material and fixed therein, and the other end is formed of a 'closely-wound coil spring' connected to the second electrode lead in the form of a coil spring. [17] The other end of the coil spring may be welded to one end of a metal tube, as guided by a catheter, to form a second electrode lead. [18] On the other hand, the first electrode comprises the first electrode tip and the first electrode lead, and the first electrode lead is in the form of a metal wire, wherein the first electrode lead is connected to the first electrode tip and is inserted into the coil spring. The second electrode comprises the second electrode tip and the second electrode lead, and the second electrode lead may be in the form of a metal wire, wherein the second electrode lead is connected to the second electrode tip, inserted into the coil spring, and disposed in parallel with the first electrode lead. [19] The first electrode tip and the second electrode tip are bonded by an electrically insulating material to form an electrode tip assembly, and one end of the coil spring may be fixed on the electrode tip assembly. [20] The part to which the coil spring is bonded is formed to be protruded in the electrode tip assembly, and one end of the coil spring may be fixed on the part to which the coil spring is bonded. [21] The other end of the coil spring may be fixed on one end of the tube. [22] The coil spring is made from metals, preferably metals such as stainless steel, common alloy steel, titanium steel wire, and shape memory alloy. Advantageous Effects [23] The radiofrequency electrode for selective ablation of a body tissue according to the present invention can be used for ablating a tissue in a body, by inserting, through a catheter, a radiofrequency electrode tip to a tissue, and then by controlling the direction and position of the electrode tip through pulling an electrode lead in the form a metal wire to modify the coil spring part, and thus easily positioning the electrode tip in a specific region. Brief Description of the Drawings [24] Fig. 1 is a perspective view of the radiofrequency electrode according to the first Example of the present invention. [25] Fig. 2 is a perspective view of separation of an external electrode and an internal -5 electrode of Fig. 1. Fig. 3 is a detailed view of the end part of the radiofrequency electrode of Fig. 1. Fig. 4 is a perspective view illustrating an operator in a trigger type, to which the radiofrequency electrode of an embodiment of the present invention is bonded. 5 Fig. 5 is a state diagram illustrating the control of the direction and the position of the electrode tip using the radiofrequency electrode of an embodiment of the present invention. Fig. 6 is a perspective view of the radiofrequency electrode according to the second Example of the present invention. 10 Figs. 7(a) to 7(c) are diagrams illustrating the assembly process of the radiofrequency electrode of Fig. 6. Fig. 8 is a state diagram illustrating the treatment of the hernia of the intervertebral discs in the spine using radiofrequency. 15 Brief Description on the Symbols in the Drawings 100, 200: Radiofrequency electrode 110, 210: First electrode 112, 212: First electrode tip 114, 214: First electrode lead 20 120, 220: Second electrode 122, 222: Second electrode tip 124, 224: Second electrode lead 126: Metal tube 230: Coil spring 25 232: Metal tube 140, 240: Electrically insulating material 242: Bonded part of coil spring 150, 250: Electrode tip assembly 160: Operator 30 162: Trigger 60: Catheter Best Mode Hereinbelow, preferable Examples of the present invention will be described in 35 detail with reference to the accompanying figures. Fig. 1 is a perspective view of the radiofrequency electrode according to the first Example of the present invention, Fig. 2 is a perspective view of separation of an 2294431_1 (GHMatters) 4/06110 - Sa external electrode and an internal electrode of Fig. 1, and Fig. 3 is a detailed view of the end part of the radiofrequency electrode of Fig. 1. As illustrated in the figures, the radiofrequency electrode 100 of the first Example is configured such that the first 2294431_1 (GHMatters) 4/06110 WO 2007/055521 PCT/KR2006/004683 electrode 110 in the form of a metal wire is inserted into the second electrode 120 having its end part in the form of a coil spring. [51] The first electrode 110 and the second electrode 120 are guided by a catheter 60 (illustrated in Fig. 8) and inserted into a body tissue. [52] The first electrode 110 is configured such that the first electrode lead 114 is inserted into the second electrode 120 and disposed therein, and the first electrode tip 112 in the sharp cylindrical form is connected to the end part of the first electrode lead 114. The first electrode lead 114 is coated by a well known insulator, and the first electrode tip 112 is not coated. [53] The second electrode 120 is configured such that the second electrode tip 122 in the form of a closely-wound coil spring is connected to the end part of the second electrode lead 124 in the form of a coil spring, and metal tube 126 is welded in the opposite side of the second electrode tip 122 to wholly form the second electrode 120. The second electrode lead 124 and the metal tube 126 are coated by a well known insulator, and the second electrode tip 122 in the form of a closely-wound coil spring is not coated. The second electrode 120 has an outer diameter (outer diameters of the metal tube and the coil spring) of 0.8 to 2.5 mm. [54] The first electrode tip 112 and the second electrode tip 122 are bonded to each other by a electrically insulating material 140 coated by an insulator in the cylindrical form to form an electrode tip assembly 150. The first electrode tip 112 is closely adhered and fixed on the side of the end part of the electrically insulating material 140, and the second electrode tip 122 is interposed and fixed on the other side of the electrically insulating material 140. [55] Further, in the second electrode lead 124 in the form of a coil spring, the end part connected to the second electrode tip 122 is bent in the free state, thus to be pigtail- or J-shaped. [56] The first electrode lead 114 is easily bent by an external force, and made from materials having a high tensile strength. When the first electrode lead 114 is inserted into the second electrode lead 124 in the form of a coil spring, the end part of the first electrode lead 114 is also bent to be pigtail- or J-shaped, according to the shape of the bent second electrode lead. The first electrode lead is connected to the trigger 162 of the below-described operator 160, and functions to control the direction of the electrode tip by the operation of the trigger 162. [57] Any materials for the first electrode, the second electrode, and the coil spring can be used, as long as radiofrequency current flows therein, preferably used are metals, and more preferably used are metals such as stainless steel, common steel alloy, titanium steel wire, and shape memory alloy. [58] Such configured radiofrequency electrode 100 is, for example, connected to the WO 2007/055521 PCT/KR2006/004683 operator 160 for use, as illustrated in Fig. 4. If the first electrode 110, which had been inserted into the second electrode 120 by operation of the trigger 162 in the operator 160, is pulled, the electrode tip assembly 150 is also pulled, the bent part (the pigtail or J-shaped part) of the end part of the second electrode 120 in the form of a coil spring is unbent, and if the controller 162 is restored to its original position, the elastic force from the bent part of the second electrode 120 allows restoration of the bent form which is an original form, thus making it possible to control the position and the direction of the electrode tip assembly 150. [59] By such the operation, Figs. 5(a) to 5(c) illustrates a method in which an electrode tip assembly is inserted into the intervertebral discs to control the direction and the position of the electrode tip assembly. [60] As illustrated in Fig. 5, when the electrode tip assembly 150 is inserted into the annulus fibrosus 20 of the intervertebral discs, the controller 162 (illustrated in Fig. 4) is pulled to almost unfold the bent part of the end part of the radiofrequency electrode 100. After the electrode tip assembly 150 is inserted into the outer skin 20, if one slowly release the trigger 162 (illustrated in Fig. 4), the end part of the radiofrequency electrode 100 is again bent, as illustrated in Figs. 5(b) and 5(c). If the trigger 162 is pulled or released, and correspondingly the electrode tip is unbent or bent, the electrode tip assembly 150 can be easily positioned in the nucleus pulposus part 10 in the annulus fibrosus 20 in the direction and the position, as shown by the broken lined arrow, thus make it possible to easily perform the operation for applying ra diofrequency. [61] Fig. 6 is a perspective view of the radiofrequency electrode according to the second Example of the present invention, and Fig. 7 is a diagram illustrating the assembly process of the radiofrequency electrode of Fig. 6. [62] As illustrated in the figures, the radiofrequency electrode 200 of the second Example is configured such that a separate coil spring 230 is provided at the end part of the radiofrequency electrode, and the first electrode 210 in the form a metal wire and the second electrode 220 are inserted into the coil spring 230 and disposed in parallel to each other. [63] The first electrode 210 and the second electrode 220 are guided by the catheter 60 (illustrated in Fig. 8) and inserted into the body tissue. A coil spring 230, by which the first electrode 210 and the second electrode 220 are guided, is provided at the end parts of the first electrode 210 and the second electrode 220. [64] The first electrode 210 is configured such that the first electrode lead 214 in the form of a metal wire is inserted into the coil spring 230 and disposed therein, and the first electrode tip 212 in the sharp cylindrical form is connected to the end part of the first electrode lead 214. The first electrode lead 214 is coated by a well known WO 2007/055521 PCT/KR2006/004683 insulator, and the first electrode tip 212 is not coated. [65] The second electrode 220 is configured such that the second electrode lead 224 in the form of a metal wire is inserted into the coil spring 230 and disposed in parallel with the electrode lead 214, and the second electrode tip 222 in the cylindrical form is connected to the end part of the second electrode lead 224. The second electrode lead 224 is coated by a well known insulator, and the second electrode tip 222 is not coated. [66] The first electrode tip 212 and the second electrode tip 222 are bonded to a electrically insulating material 240 in the cylindrical form coated by an insulator to form an electrode tip 250. The first electrode tip 212 is closely adhered to and fixed on the side of the end part of the electrically insulating material 240, and the second electrode tip 222 is interposed and fixed on the side of the other end part of the electrically insulating material 240. In the electrode tip 250, the cylindrical part 242 to which the coil spring is bonded, that is, the part to which the coil spring 230 is bonded, is protruded in the opposite side of the electrically insulating material 240, and the end part of the coil spring 230 is inserted into the outer surface of the part 242 to which the coil spring is bonded. The part 242 to which the coil spring is bonded is coated by a well known insulator. [67] In the coil spring 230, a metal tube 232 is welded to the opposite side of the electrode tip 250. [68] In the coil spring 230, the end part connected to the second electrode tip 250 is bent in the free state, thus to be pigtail- or J-shaped. [69] In the first electrode lead 214 and the second electrode lead 224, which are inserted into the coil spring 230, even the end part connected to the electrode tip 250 may be bent in the free state, thus to be pigtail- or J-shaped. [70] Any materials for the first electrode 210, the second electrode 220, the coil spring 230, and the tube 232 can be used, as long as radiofrequency current flows therein, preferably used are metals, and more preferably used are metals such as stainless steel, common steel alloy, titanium steel wire, and shape memory alloy. Thus prepared coil spring 230 and the tube 232 are coated by a well known insulator so as not to be affected upon applying radiofrequency between the first electrode tip 212 and the second electrode tip 222. [71] Figs. 7(a) to 7(c) illustrate the assembly process of the radiofrequency electrode of the second Example of the present invention. As illustrated in Fig. 7(a), the first electrode tip 212 and the first electrode lead 214 are assembled into a first electrode 210, while the second electrode tip 222 and the second electrode lead 224 are assembled into a second electrode 220. Thereafter, as illustrated in Fig. 7(b), an electrically insulating material 240 is bonded between the first electrode tip 212 and the second electrode tip 222, while the part 242 to which the coil spring is bonded is WO 2007/055521 PCT/KR2006/004683 bonded in the opposite side of the electrically insulating material 240 of the second electrode tip 222 to form an electrode tip 250. Then, as illustrated in Fig. 7(c), the coil spring 230 having its end part bent is inserted and fixed to the part 242 to which the coil spring is bonded is bonded to obtain a radiofrequency electrode 200. [72] Thus configured radiofrequency electrode 200 according to the second Example of the present invention is bonded to a trigger-type operator 160 as illustrated in Fig. 4 for use, as in the radiofrequency electrode 100 according to the first Example of the present invention, and the operation using the operator is as illustrated in Figs. 5(a) to 5(c). That is, an electrode tip is inserted into the nucleus pulposus 10 of the inter vertebral discs, and controlled in the direction and the position, wherein if the first electrode 210 and the second electrode 220, which had been inserted into the coil spring 230 by operation of the trigger 162 in the operator 160, are pulled, the electrode tip 250 is also pulled, the bent part (the J-shaped part of the end part of the coil spring 230 is unbent, and if the controller 162 is restored to its original position, the elastic force from the bent part of the coil spring 230 allows restoration of the bent form which is an original form, thus making it possible to control the position and the direction of the electrode tip 250. [73] In the second Example of the present invention, the first electrode lead 214 and the second electrode lead 224 are both in the linear forms, and the first electrode lead 214 and the second electrode lead 224 are configured to be located inside of a separate coil spring 230. Thus, the second electrode lead 124 is shorter than that in the coil form of the first Example, which allows a lower current loss due to resistance, and a separate coil spring 230 protects the first electrode lead 214 and the second electrode lead 224, which eliminates the noise due to outer currents or electromagnetic wave, thereby it provides an effect of shielding an electromagnetic wave. [74] According to the radiofrequency electrode of the present invention, local ablation can be performed with various applications, even in the case of the regions to which a linear electrode cannot be easily accessed, such as the hernia of the intervertebral discs. Further, if a local ablation of a body tissue in addition to the above-described cases is required, for example: to ablate a tumor or a cancer tissue; to ablate a thrombus in a blood vessel; to ablate a plaque in a blood vessel; to ablate a stenosed area in a blood vessel; to ablate a fibroma; to ablate a myoma of the uterus; to ablate an apocrine gland for alleviation of an osmidrosis; to ablate a polyp in the small or large intestine; to ablate a tissue in the stomach, small intestine or large intestine; to ablate a stenosed area in the urethra; to ablate a stenosed area in the knee cartilage; to ablate an un desirably grown nerve tissue; or the like. [75] On the other hand, the coil spring made from the metal materials in the present invention, as compared with the coil spring made from polymeric materials, can - 10 provide a spring back force with a predetermined curvature (pre-curve), and thus makes it possible to locally control the direction of the electrode tip, to perform a precise operation, to have heat resistance against a neutral gas separated into electrons and ions at around 700*C by radiofrequency, to eliminate the deterioration by the electrode in the s case of controlling an electrode in the form of a metal wire, to perform insulation employing various coating techniques, and to have a low production cost. In the claims which follow and in the preceding description of the invention, except where the context requires otherwise due to express language or necessary implication, the word "comprise" or variations such as "comprises" or "comprising" is 10 used in an inclusive sense, i.e. to specify the presence of the stated features but not to preclude the presence or addition of further features in various embodiments of the invention. It is to be understood that, if any prior art publication is referred to herein, such reference does not constitute an admission that the publication forms a part of the is common general knowledge in the art, in Australia or any other country. 2294431_1 (GHMatters) 4106/10

AU2006312419A 2005-11-09 2006-11-09 Radio frequency ablation electrode for selected tissue removal Ceased AU2006312419B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR20050106763 2005-11-09
KR10-2005-0106763 2005-11-09
PCT/KR2006/004683 WO2007055521A1 (en) 2005-11-09 2006-11-09 Radio frequency ablation electrode for selected tissue removal

Publications (2)

Publication Number Publication Date
AU2006312419A1 AU2006312419A1 (en) 2007-05-18
AU2006312419B2 true AU2006312419B2 (en) 2010-08-05

Family

ID=38023465

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006312419A Ceased AU2006312419B2 (en) 2005-11-09 2006-11-09 Radio frequency ablation electrode for selected tissue removal

Country Status (6)

Country Link
US (1) US20080249525A1 (en)
EP (1) EP1945298B1 (en)
JP (2) JP5149191B2 (en)
KR (1) KR100778142B1 (en)
AU (1) AU2006312419B2 (en)
WO (1) WO2007055521A1 (en)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
DE202004021952U1 (en) 2003-09-12 2013-06-19 Vessix Vascular, Inc. Selectable eccentric remodeling and / or ablation of atherosclerotic material
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
JP5479901B2 (en) 2006-10-18 2014-04-23 べシックス・バスキュラー・インコーポレイテッド Induction of desired temperature effects on body tissue
EP2455036B1 (en) 2006-10-18 2015-07-15 Vessix Vascular, Inc. Tuned RF energy and electrical tissue characterization for selective treatment of target tissues
EP2076194B1 (en) 2006-10-18 2013-04-24 Vessix Vascular, Inc. System for inducing desirable temperature effects on body tissue
KR101133947B1 (en) 2008-06-09 2012-04-13 고려대학교 산학협력단 Steerable ablation electrode and guide hole for selected tissue removal
JP5575777B2 (en) * 2008-09-30 2014-08-20 ディファイン, インコーポレイテッド System used to treat vertebral fractures
US8758349B2 (en) * 2008-10-13 2014-06-24 Dfine, Inc. Systems for treating a vertebral body
WO2010048676A1 (en) 2008-10-31 2010-05-06 Cathrx Ltd A catheter assembly
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
AU2009314133B2 (en) 2008-11-17 2015-12-10 Vessix Vascular, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
JP2012529335A (en) * 2009-06-09 2012-11-22 ユー アンド アイ コーポレーション Directionally adjustable electrode body and guide tube for selective removal of body tissue
US10058336B2 (en) 2010-04-08 2018-08-28 Dfine, Inc. System for use in treatment of vertebral fractures
US9277955B2 (en) 2010-04-09 2016-03-08 Vessix Vascular, Inc. Power generating and control apparatus for the treatment of tissue
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8870863B2 (en) 2010-04-26 2014-10-28 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
US9526507B2 (en) 2010-04-29 2016-12-27 Dfine, Inc. System for use in treatment of vertebral fractures
WO2011137357A1 (en) 2010-04-29 2011-11-03 Dfine, Inc. System for use in treatment of vertebral fractures
WO2011137377A1 (en) 2010-04-29 2011-11-03 Dfine, Inc. System for use in treatment of vertebral fractures
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US20120065634A1 (en) * 2010-09-14 2012-03-15 Korea University Industrial & Academic Collaboration Foundation Method of treating an inter-vertebral disc
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
WO2012071464A1 (en) 2010-11-22 2012-05-31 Dfine, Inc. System for use in treatment of vertebral fractures
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
WO2012100095A1 (en) 2011-01-19 2012-07-26 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
WO2013013156A2 (en) 2011-07-20 2013-01-24 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
EP2734264B1 (en) 2011-07-22 2018-11-21 Boston Scientific Scimed, Inc. Nerve modulation system with a nerve modulation element positionable in a helical guide
US8758365B2 (en) * 2011-08-03 2014-06-24 Medtronic, Inc. Implant system including guiding accessory and methods of use
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
US10085799B2 (en) 2011-10-11 2018-10-02 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
EP2768568A1 (en) 2011-10-18 2014-08-27 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
CN108095821A (en) 2011-11-08 2018-06-01 波士顿科学西美德公司 Hole portion renal nerve melts
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
CN104254368B (en) 2011-12-23 2016-10-12 维西克斯血管公司 Tissue or body tissue via the body passageway near the reconstruction method and apparatus
EP2797534A1 (en) 2011-12-28 2014-11-05 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
JP2015057080A (en) * 2012-01-12 2015-03-26 テルモ株式会社 Body tissue cauterization system
AU2013240565B2 (en) 2012-03-27 2017-07-20 Dfine, Inc. Methods and systems for use in controlling tissue ablation volume by temperature monitoring
WO2014032016A1 (en) 2012-08-24 2014-02-27 Boston Scientific Scimed, Inc. Intravascular catheter with a balloon comprising separate microporous regions
CN104780859B (en) 2012-09-17 2017-07-25 波士顿科学西美德公司 Self-positioning electrode system and method for renal regulation
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US9918766B2 (en) 2012-12-12 2018-03-20 Dfine, Inc. Devices, methods and systems for affixing an access device to a vertebral body for the insertion of bone cement
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
WO2014143571A1 (en) 2013-03-11 2014-09-18 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
JP6139772B2 (en) 2013-03-15 2017-05-31 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Control unit for use with electrode pads and method for estimating leakage
WO2014150553A1 (en) 2013-03-15 2014-09-25 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
CN105101899B (en) * 2013-03-28 2017-07-14 奥林巴斯株式会社 Medical apparatus and medical system
JP2016523147A (en) 2013-06-21 2016-08-08 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Renal denervation balloon catheter with a riding-type electrode support
JP2016524949A (en) 2013-06-21 2016-08-22 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Medical device for renal nerve ablation having a rotatable shaft
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
AU2014284558B2 (en) 2013-07-01 2017-08-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
WO2015006573A1 (en) 2013-07-11 2015-01-15 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
WO2015010074A1 (en) 2013-07-19 2015-01-22 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
CN105555220B (en) 2013-07-22 2019-05-17 波士顿科学国际有限公司 Medical instrument for renal nerve ablation
US9895194B2 (en) 2013-09-04 2018-02-20 Boston Scientific Scimed, Inc. Radio frequency (RF) balloon catheter having flushing and cooling capability
CN105592778B (en) 2013-10-14 2019-07-23 波士顿科学医学有限公司 High-resolution cardiac mapping electrod-array conduit
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
AU2014334574B2 (en) 2013-10-15 2017-07-06 Boston Scientific Scimed, Inc. Medical device balloon
US10271898B2 (en) 2013-10-25 2019-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
CN106572881B (en) 2014-02-04 2019-07-26 波士顿科学国际有限公司 Substitution of the heat sensor on bipolar electrode is placed
US9901392B2 (en) 2015-05-11 2018-02-27 Dfine, Inc. System for use in treatment of vertebral fractures

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416509B1 (en) * 1995-06-23 2002-07-09 Gyrus Medical Limited Electrosurgical generator and system

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3521620A (en) * 1967-10-30 1970-07-28 William A Cook Vascular coil spring guide with bendable tip
US4043342A (en) * 1974-08-28 1977-08-23 Valleylab, Inc. Electrosurgical devices having sesquipolar electrode structures incorporated therein
US4311145A (en) * 1979-07-16 1982-01-19 Neomed, Inc. Disposable electrosurgical instrument
AU660444B2 (en) * 1991-02-15 1995-06-29 Ingemar H. Lundquist Torquable catheter and method
US5327905A (en) * 1992-02-14 1994-07-12 Boaz Avitall Biplanar deflectable catheter for arrhythmogenic tissue ablation
US5217458A (en) * 1992-04-09 1993-06-08 Everest Medical Corporation Bipolar biopsy device utilizing a rotatable, single-hinged moving element
US5318525A (en) * 1992-04-10 1994-06-07 Medtronic Cardiorhythm Steerable electrode catheter
US5370675A (en) * 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US5464404A (en) * 1993-09-20 1995-11-07 Abela Laser Systems, Inc. Cardiac ablation catheters and method
US5582609A (en) 1993-10-14 1996-12-10 Ep Technologies, Inc. Systems and methods for forming large lesions in body tissue using curvilinear electrode elements
EP1025807B1 (en) * 1995-06-23 2004-12-08 Gyrus Medical Limited An electrosurgical instrument
US5863291A (en) * 1996-04-08 1999-01-26 Cardima, Inc. Linear ablation assembly
GB2314274A (en) * 1996-06-20 1997-12-24 Gyrus Medical Ltd Electrode construction for an electrosurgical instrument
US6120520A (en) * 1997-05-27 2000-09-19 Angiotrax, Inc. Apparatus and methods for stimulating revascularization and/or tissue growth
JP2002501769A (en) * 1997-10-30 2002-01-22 イー.ピー. テクノロジーズ, インコーポレイテッド Catheter distal assembly comprising a pull wire
US6048329A (en) * 1996-12-19 2000-04-11 Ep Technologies, Inc. Catheter distal assembly with pull wires
US5861024A (en) * 1997-06-20 1999-01-19 Cardiac Assist Devices, Inc Electrophysiology catheter and remote actuator therefor
KR20010021983A (en) * 1997-07-18 2001-03-15 고블 콜린 찰즈 오웬 An electrosurgical instrument
US6238389B1 (en) * 1997-09-30 2001-05-29 Boston Scientific Corporation Deflectable interstitial ablation device
WO1999047058A2 (en) 1998-03-19 1999-09-23 Oratec Interventions, Inc. Catheter for delivery of energy to a surgical site
US6638278B2 (en) 1998-11-23 2003-10-28 C. R. Bard, Inc. Intracardiac grasp catheter
US6190382B1 (en) * 1998-12-14 2001-02-20 Medwaves, Inc. Radio-frequency based catheter system for ablation of body tissues
US6916306B1 (en) * 2000-11-10 2005-07-12 Boston Scientific Scimed, Inc. Steerable loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
AU2002245243B2 (en) * 2001-01-11 2007-03-22 Angiodynamics, Inc. Bone-treatment instrument and method
CA2445392C (en) * 2001-05-10 2011-04-26 Rita Medical Systems, Inc. Rf tissue ablation apparatus and method
US6745079B2 (en) * 2001-11-07 2004-06-01 Medtronic, Inc. Electrical tissue stimulation apparatus and method
US7107105B2 (en) * 2002-09-24 2006-09-12 Medtronic, Inc. Deployable medical lead fixation system and method
JP2004305250A (en) * 2003-04-02 2004-11-04 Toray Ind Inc Device and method for treatment of cardiac arrhythmias
WO2004098701A1 (en) * 2003-05-06 2004-11-18 Enpath Medical, Inc. Rotatable lead introducer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416509B1 (en) * 1995-06-23 2002-07-09 Gyrus Medical Limited Electrosurgical generator and system
EP0754437B2 (en) * 1995-06-23 2004-12-22 Gyrus Medical Limited An electrosurgical generator and system

Also Published As

Publication number Publication date
KR100778142B1 (en) 2007-11-29
JP2009513296A (en) 2009-04-02
EP1945298A4 (en) 2011-06-01
JP5149191B2 (en) 2013-02-20
EP1945298A1 (en) 2008-07-23
EP1945298B1 (en) 2013-04-17
AU2006312419A1 (en) 2007-05-18
US20080249525A1 (en) 2008-10-09
KR20070049995A (en) 2007-05-14
JP2013006046A (en) 2013-01-10
JP5642127B2 (en) 2014-12-17
WO2007055521A1 (en) 2007-05-18

Similar Documents

Publication Publication Date Title
US7267683B2 (en) Method for treating intervertebral discs
US7357798B2 (en) Systems and methods for electrosurgical prevention of disc herniations
US6277114B1 (en) Electrode assembly for an electrosurical instrument
JP4292360B2 (en) Device for forming a shaped axial hole through the spine
US8795271B2 (en) Surgical probe for supporting inflatable therapeutic devices in contact with tissue in or around body orifice and within tumors
US6379351B1 (en) Electrosurgical method for the removal of pacemaker leads
JP3366835B2 (en) Mechanical clot treatment device
JP5722938B2 (en) Apparatus and method for atherectomy
US6726684B1 (en) Methods for electrosurgical spine surgery
ES2250820T3 (en) An electrochirurgical instrument.
AU730446B2 (en) Urological stent therapy system and method
JP3128242B2 (en) Medical probe device
US8082043B2 (en) Method for treating intervertebral disc degeneration
EP1637087B1 (en) Systems and methods for electrosurgical tissue treatment in the presence of electrically conductive fluid
AU709895B2 (en) Method and device for permanent vessel occlusion
US8491520B2 (en) Method for operating a selective stiffening catheter
US6763836B2 (en) Methods for electrosurgical tendon vascularization
US6283988B1 (en) Bronchial stenter having expandable electrodes
EP1341463B1 (en) Ablation catheter assembly for isolating a pulmonary vein
JP2726756B2 (en) Catheter having an inflatable wire mesh tip
US7104986B2 (en) Intervertebral disc replacement method
US6127597A (en) Systems for percutaneous bone and spinal stabilization, fixation and repair
EP1674044B1 (en) Systems for organ resection
JP3391466B2 (en) Electrosurgical catheter system and a catheter for recanalization of occluded body lumens
US5873855A (en) Systems and methods for electrosurgical myocardial revascularization

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired