AU2006252629A1 - Substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases - Google Patents
Substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases Download PDFInfo
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- AU2006252629A1 AU2006252629A1 AU2006252629A AU2006252629A AU2006252629A1 AU 2006252629 A1 AU2006252629 A1 AU 2006252629A1 AU 2006252629 A AU2006252629 A AU 2006252629A AU 2006252629 A AU2006252629 A AU 2006252629A AU 2006252629 A1 AU2006252629 A1 AU 2006252629A1
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- substituted
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- alkyl
- amino
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
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- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68606205P | 2005-05-31 | 2005-05-31 | |
| US60/686,062 | 2005-05-31 | ||
| PCT/US2006/020986 WO2006130613A2 (en) | 2005-05-31 | 2006-05-30 | Substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2006252629A1 true AU2006252629A1 (en) | 2006-12-07 |
Family
ID=37482228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006252629A Abandoned AU2006252629A1 (en) | 2005-05-31 | 2006-05-30 | Substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1896462A2 (https=) |
| JP (1) | JP2008542382A (https=) |
| CN (1) | CN101233129A (https=) |
| AU (1) | AU2006252629A1 (https=) |
| CA (1) | CA2650999A1 (https=) |
| WO (1) | WO2006130613A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ604708A (en) | 2010-05-20 | 2015-05-29 | Array Biopharma Inc | Macrocyclic compounds as trk kinase inhibitors |
| ES2541054T3 (es) * | 2010-10-20 | 2015-07-15 | Université De Bordeaux | Firmas del resultado clínico en tumores estromales gastrointestinales y método de tratamiento de tumores estromales gastrointestinales |
| BR112018000808A2 (pt) | 2015-07-16 | 2018-09-04 | Array Biopharma Inc | compostos de pirazolo[1,5-a]piridina substituída como inibidores de ret cinase |
| TWI704148B (zh) | 2016-10-10 | 2020-09-11 | 美商亞雷生物製藥股份有限公司 | 作為ｒｅｔ激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物 |
| TWI752098B (zh) | 2016-10-10 | 2022-01-11 | 美商亞雷生物製藥股份有限公司 | 作為ret激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物 |
| US11168090B2 (en) | 2017-01-18 | 2021-11-09 | Array Biopharma Inc. | Substituted pyrazolo[1,5-a]pyrazines as RET kinase inhibitors |
| WO2018136663A1 (en) | 2017-01-18 | 2018-07-26 | Array Biopharma, Inc. | Ret inhibitors |
| JOP20190213A1 (ar) | 2017-03-16 | 2019-09-16 | Array Biopharma Inc | مركبات حلقية ضخمة كمثبطات لكيناز ros1 |
| TWI791053B (zh) | 2017-10-10 | 2023-02-01 | 美商亞雷生物製藥股份有限公司 | 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之結晶形式及其醫藥組合物 |
| TWI812649B (zh) | 2017-10-10 | 2023-08-21 | 美商絡速藥業公司 | 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之調配物 |
| CN111615514B (zh) | 2018-01-18 | 2022-10-11 | 奥瑞生物药品公司 | 作为ret激酶抑制剂的取代的吡唑并[4,3-c]吡啶化合物 |
| EP3740491A1 (en) | 2018-01-18 | 2020-11-25 | Array Biopharma, Inc. | Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors |
| WO2019143991A1 (en) | 2018-01-18 | 2019-07-25 | Array Biopharma Inc. | SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS AS RET KINASE INHIBITORS |
| EP3849986B1 (en) | 2018-09-10 | 2022-06-08 | Array Biopharma, Inc. | Fused heterocyclic compounds as ret kinase inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU778723B2 (en) * | 1999-08-23 | 2004-12-16 | Kyorin Pharmaceutical Co. Ltd. | Substituted benzylthiazolidine-2,4-dione derivatives |
-
2006
- 2006-05-30 WO PCT/US2006/020986 patent/WO2006130613A2/en not_active Ceased
- 2006-05-30 EP EP06771644A patent/EP1896462A2/en not_active Withdrawn
- 2006-05-30 CA CA002650999A patent/CA2650999A1/en not_active Abandoned
- 2006-05-30 JP JP2008514781A patent/JP2008542382A/ja not_active Withdrawn
- 2006-05-30 AU AU2006252629A patent/AU2006252629A1/en not_active Abandoned
- 2006-05-30 CN CNA2006800281850A patent/CN101233129A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1896462A2 (en) | 2008-03-12 |
| CA2650999A1 (en) | 2006-12-07 |
| WO2006130613A2 (en) | 2006-12-07 |
| CN101233129A (zh) | 2008-07-30 |
| JP2008542382A (ja) | 2008-11-27 |
| WO2006130613A3 (en) | 2007-02-08 |
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| Date | Code | Title | Description |
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| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |