AU2004216133B2 - Adenosine A1 receptor antagonist for the treatment of cardiac and renal diseases - Google Patents
Adenosine A1 receptor antagonist for the treatment of cardiac and renal diseases Download PDFInfo
- Publication number
- AU2004216133B2 AU2004216133B2 AU2004216133A AU2004216133A AU2004216133B2 AU 2004216133 B2 AU2004216133 B2 AU 2004216133B2 AU 2004216133 A AU2004216133 A AU 2004216133A AU 2004216133 A AU2004216133 A AU 2004216133A AU 2004216133 B2 AU2004216133 B2 AU 2004216133B2
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- tricyclo
- nonyl
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/52—Purines, e.g. adenine
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44995303P | 2003-02-24 | 2003-02-24 | |
US60/449,953 | 2003-02-24 | ||
US45049903P | 2003-02-25 | 2003-02-25 | |
US45050003P | 2003-02-25 | 2003-02-25 | |
US60/450,499 | 2003-02-25 | ||
US60/450,500 | 2003-02-25 | ||
US45132603P | 2003-02-28 | 2003-02-28 | |
US60/451,326 | 2003-02-28 | ||
US46481203P | 2003-04-21 | 2003-04-21 | |
US46481503P | 2003-04-21 | 2003-04-21 | |
US46481103P | 2003-04-21 | 2003-04-21 | |
US46481303P | 2003-04-21 | 2003-04-21 | |
US60/464,812 | 2003-04-21 | ||
US60/464,815 | 2003-04-21 | ||
US60/464,811 | 2003-04-21 | ||
US60/464,813 | 2003-04-21 | ||
PCT/US2004/005755 WO2004075856A2 (en) | 2003-02-24 | 2004-02-24 | Adenosine a1 receptor antagonist for the treatment of cardiac and renal diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2004216133A1 AU2004216133A1 (en) | 2004-09-10 |
AU2004216133B2 true AU2004216133B2 (en) | 2008-12-04 |
Family
ID=32931788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2004216133A Ceased AU2004216133B2 (en) | 2003-02-24 | 2004-02-24 | Adenosine A1 receptor antagonist for the treatment of cardiac and renal diseases |
Country Status (9)
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060293312A1 (en) * | 2003-04-25 | 2006-12-28 | Howard Dittrich | Method of improved diuresis in individuals with impaired renal function |
WO2004096228A1 (en) * | 2003-04-25 | 2004-11-11 | Novacardia, Inc. | Method of improved diuresis in individuals with impaired renal function |
JP2007532671A (ja) * | 2004-04-16 | 2007-11-15 | ノヴァカーディア,インク. | アデノシンa1受容体アンタゴニストおよびアルドステロン阻害剤を含む併用療法 |
CA2622911C (en) * | 2005-09-16 | 2016-12-06 | Cornell Research Foundation, Inc. | Methods for reducing cd36 expression |
CA2648281A1 (en) * | 2006-04-06 | 2007-10-18 | Novacardia, Inc. | Co-administration of adenosine a1 receptor antagonists and anticonvulsants |
JP2009540003A (ja) * | 2006-06-16 | 2009-11-19 | ノヴァカーディア,インク. | Aa1raの低頻度投与を含む腎機能の長期間にわたる改善 |
TW200808819A (en) * | 2006-06-19 | 2008-02-16 | Solvay Pharm Gmbh | Use of adenosine A1 antagonists in radiocontrast media induced nephrophaty |
WO2008121893A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist |
US20080242684A1 (en) * | 2007-03-29 | 2008-10-02 | Howard Dittrich | Methods of administration of adenosine a1 receptor antagonists |
US8722736B2 (en) | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
US8426467B2 (en) | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
CN101909612A (zh) * | 2007-12-27 | 2010-12-08 | 拜尔动物保健有限责任公司 | 使用β-受体阻滞剂治疗心脏病 |
CN109890364B (zh) * | 2016-10-03 | 2023-10-17 | 儿童医疗中心公司 | 糖尿病肾病的预防和治疗 |
Citations (1)
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CN1129105A (zh) * | 1994-09-16 | 1996-08-21 | 赵明玉 | 预防和治疗偏头痛的偏头痛片 |
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US5290782A (en) * | 1989-09-01 | 1994-03-01 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
JPH06102662B2 (ja) * | 1989-09-01 | 1994-12-14 | 協和醗酵工業株式会社 | キサンチン誘導体 |
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GEP20043267B (en) * | 1999-11-12 | 2004-06-25 | Biogen Inc Us | Adenosine Receptor Antagonists, Methods of Making and Using the Same |
US20050038017A1 (en) * | 1999-12-22 | 2005-02-17 | Wolff Andrew A. | Method and composition for restoring diuretic and renal function |
US20020123485A1 (en) * | 2000-07-27 | 2002-09-05 | Alexander John C. | Epoxy steroidal aldosterone antagonist and beta-adrenergic antagonist combination therapy for treatment of congestive heart failure |
DE60133931D1 (de) * | 2000-12-01 | 2008-06-19 | Biogen Idec Inc | Kondensierte purinderivate als a1-adenosinrezeptorantagonisten |
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2004
- 2004-02-23 US US10/785,446 patent/US20040229901A1/en not_active Abandoned
- 2004-02-24 JP JP2006503887A patent/JP2006518765A/ja active Pending
- 2004-02-24 AU AU2004216133A patent/AU2004216133B2/en not_active Ceased
- 2004-02-24 EP EP04714224A patent/EP1603545A2/en not_active Withdrawn
- 2004-02-24 BR BRPI0407494-7A patent/BRPI0407494A/pt not_active IP Right Cessation
- 2004-02-24 MX MXPA05008805A patent/MXPA05008805A/es not_active Application Discontinuation
- 2004-02-24 KR KR1020057015605A patent/KR20050106038A/ko not_active Application Discontinuation
- 2004-02-24 EP EP09160652A patent/EP2087888A1/en not_active Withdrawn
- 2004-02-24 CA CA002516730A patent/CA2516730A1/en not_active Abandoned
- 2004-02-24 WO PCT/US2004/005755 patent/WO2004075856A2/en active Application Filing
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CN1129105A (zh) * | 1994-09-16 | 1996-08-21 | 赵明玉 | 预防和治疗偏头痛的偏头痛片 |
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DATABASE WPI Section Ch, Week 199751 Derwent Publications Ltd., London, GB; Class B03, AN 1997-550488 XP002293139 & CN 1 129 105 A (ZHAO M) 21 August 1996 (1996-08-21) * |
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EP2087888A1 (en) | 2009-08-12 |
MXPA05008805A (es) | 2006-02-22 |
WO2004075856A2 (en) | 2004-09-10 |
EP1603545A2 (en) | 2005-12-14 |
KR20050106038A (ko) | 2005-11-08 |
CA2516730A1 (en) | 2004-09-10 |
BRPI0407494A (pt) | 2006-02-14 |
AU2004216133A1 (en) | 2004-09-10 |
WO2004075856A3 (en) | 2005-03-31 |
JP2006518765A (ja) | 2006-08-17 |
US20040229901A1 (en) | 2004-11-18 |
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