AU2002316939A1 - Anthranilic acid amides with a heteroarylsulfonyl side chain, and use thereof as antiarrhythmic active substances - Google Patents
Anthranilic acid amides with a heteroarylsulfonyl side chain, and use thereof as antiarrhythmic active substancesInfo
- Publication number
- AU2002316939A1 AU2002316939A1 AU2002316939A AU2002316939A AU2002316939A1 AU 2002316939 A1 AU2002316939 A1 AU 2002316939A1 AU 2002316939 A AU2002316939 A AU 2002316939A AU 2002316939 A AU2002316939 A AU 2002316939A AU 2002316939 A1 AU2002316939 A1 AU 2002316939A1
- Authority
- AU
- Australia
- Prior art keywords
- side chain
- active substances
- acid amides
- anthranilic acid
- antiarrhythmic active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PXBFMLJZNCDSMP-UHFFFAOYSA-N 2-Aminobenzamide Chemical class NC(=O)C1=CC=CC=C1N PXBFMLJZNCDSMP-UHFFFAOYSA-N 0.000 title 1
- 230000003288 anthiarrhythmic Effects 0.000 title 1
- 239000003416 antiarrhythmic agent Substances 0.000 title 1
- 125000005143 heteroarylsulfonyl group Chemical group 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10128331.8 | 2001-06-12 | ||
| DE10128331A DE10128331A1 (en) | 2001-06-12 | 2001-06-12 | New 2-(heteroarylsulfonyl-amino)-benzamide derivatives, which are potassium ion channel blocking antiarrhythmic agents, useful for e.g. treating atrial fibrillation or flutter |
| PCT/EP2002/005956 WO2002100825A2 (en) | 2001-06-12 | 2002-05-31 | Anthranilic acid amides with a heteroarylsulfonyl side chain, and use thereof as antiarrhythmic active substances |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002316939A1 true AU2002316939A1 (en) | 2003-05-15 |
| AU2002316939B2 AU2002316939B2 (en) | 2006-11-23 |
Family
ID=7687941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002316939A Ceased AU2002316939B2 (en) | 2001-06-12 | 2002-05-31 | Anthranilic acid amides with a heteroarylsulfonyl side chain, and use thereof as antiarrhythmic active substances |
Country Status (41)
| Country | Link |
|---|---|
| US (2) | US6903216B2 (en) |
| EP (1) | EP1399423B9 (en) |
| JP (1) | JP4422477B2 (en) |
| KR (1) | KR100863924B1 (en) |
| CN (1) | CN1247544C (en) |
| AR (1) | AR036045A1 (en) |
| AT (1) | ATE378318T1 (en) |
| AU (1) | AU2002316939B2 (en) |
| BG (1) | BG108415A (en) |
| BR (1) | BR0210374A (en) |
| CA (1) | CA2450076C (en) |
| CO (1) | CO5540283A2 (en) |
| CR (1) | CR7140A (en) |
| CY (1) | CY1107427T1 (en) |
| CZ (1) | CZ20033361A3 (en) |
| DE (2) | DE10128331A1 (en) |
| DK (1) | DK1399423T3 (en) |
| EC (1) | ECSP034883A (en) |
| EE (1) | EE05196B1 (en) |
| ES (1) | ES2295360T3 (en) |
| HK (1) | HK1065316A1 (en) |
| HR (1) | HRP20031028A2 (en) |
| HU (1) | HUP0400159A3 (en) |
| IL (2) | IL159247A0 (en) |
| MA (1) | MA27037A1 (en) |
| MX (1) | MXPA03010875A (en) |
| MY (1) | MY138341A (en) |
| NO (1) | NO20035450D0 (en) |
| NZ (1) | NZ530081A (en) |
| OA (1) | OA12631A (en) |
| PE (1) | PE20021066A1 (en) |
| PL (1) | PL364371A1 (en) |
| PT (1) | PT1399423E (en) |
| RS (1) | RS97703A (en) |
| RU (1) | RU2293727C2 (en) |
| SK (1) | SK15222003A3 (en) |
| TN (1) | TNSN03134A1 (en) |
| TW (1) | TWI304400B (en) |
| UA (1) | UA75412C2 (en) |
| WO (1) | WO2002100825A2 (en) |
| ZA (1) | ZA200308520B (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10128331A1 (en) * | 2001-06-12 | 2002-12-19 | Aventis Pharma Gmbh | New 2-(heteroarylsulfonyl-amino)-benzamide derivatives, which are potassium ion channel blocking antiarrhythmic agents, useful for e.g. treating atrial fibrillation or flutter |
| US7119112B2 (en) * | 2002-02-28 | 2006-10-10 | Icagen, Inc. | Sulfonamides as potassium channel blockers |
| PL372936A1 (en) * | 2002-04-26 | 2005-08-08 | Ishihara Sangyo Kaisha, Ltd. | Pyridine compounds or salts thereof and herbicides containing the same |
| EP1388535A1 (en) * | 2002-08-07 | 2004-02-11 | Aventis Pharma Deutschland GmbH | Acylated arylcycloalkylamines and their use as pharmaceuticals |
| DE10312061A1 (en) * | 2003-03-18 | 2004-09-30 | Aventis Pharma Deutschland Gmbh | Combination of phenylcarboxamides with blockers of the IK channel and their use for the treatment of atrial arrhythmias |
| GB0315950D0 (en) | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| EP1489071A1 (en) * | 2003-06-18 | 2004-12-22 | 4Sc Ag | N-substituted, 3,4-dihydro-1H-isoquinoline as potassium channels modulators |
| SI1651621T1 (en) | 2003-08-08 | 2008-12-31 | Janssen Pharmaceutica Nv | 2- (quinoxalin-5-ylsulfonylamino) -benzamide compounds as cck2 modulators |
| DE10341233A1 (en) * | 2003-09-08 | 2005-03-24 | Aventis Pharma Deutschland Gmbh | Composition, useful to treat e.g. atrial fibrillation, atrial flutter and atrial arrhythmia, comprises at least one beta-blocker and at least one compound of a phenylcarboxylic acid amide derivative |
| DE102004009931A1 (en) * | 2004-02-26 | 2005-09-15 | Aventis Pharma Deutschland Gmbh | Use of specific 2-substituted benzamides for treating and preventing cardiac insufficiency, especially where caused by diastolic dysfunction, act by inhibition of the Kv1.5 potassium channel |
| GB0412986D0 (en) | 2004-06-10 | 2004-07-14 | Xention Discovery Ltd | Compounds |
| US7569589B2 (en) | 2004-07-29 | 2009-08-04 | Merck & Co., Inc. | Potassium channel inhibitors |
| MX2007003623A (en) * | 2004-09-24 | 2007-09-11 | Johnson & Johnson | Sulfonamide compounds. |
| US7576212B2 (en) | 2004-12-09 | 2009-08-18 | Xention Limited | Thieno[2,3-B] pyridines as potassium channel inhibitors |
| GB0525164D0 (en) | 2005-12-09 | 2006-01-18 | Xention Discovery Ltd | Compounds |
| AU2007245891B2 (en) * | 2006-04-27 | 2012-10-18 | Sanofi-Aventis Deutschland Gmbh | Inhibitors of the TASK-1 and TASK-3 ion channel |
| WO2008124524A2 (en) * | 2007-04-03 | 2008-10-16 | Janssen Pharmaceutica N.V. | Aryl sulfonamide compounds as modulators of the cck2 receptor |
| GB0815782D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815784D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815781D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| NZ597379A (en) * | 2009-06-29 | 2014-04-30 | Agios Pharmaceuticals Inc | Therapeutic compounds and compositions |
| ES2416071T3 (en) * | 2009-06-29 | 2013-07-30 | Merz Pharma Gmbh & Co. Kgaa | Method for preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane |
| WO2011010132A1 (en) * | 2009-07-21 | 2011-01-27 | Astrazeneca Ab | Sustained-release composition comprising compound 600 |
| FR2967674B1 (en) * | 2010-11-23 | 2012-12-14 | Pf Medicament | HETEROARYLSULFONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS |
| GB201105659D0 (en) | 2011-04-01 | 2011-05-18 | Xention Ltd | Compounds |
| NO3175985T3 (en) | 2011-07-01 | 2018-04-28 | ||
| AU2013203252B2 (en) | 2012-01-27 | 2015-08-20 | Gilead Sciences, Inc. | Combination therapies using late sodium ion channel blockers and potassium ion channel blockers |
| US9701627B2 (en) * | 2014-06-16 | 2017-07-11 | University Of Maryland, Baltimore | LRRK2 GTP binding inhibitors for treatment of Parkinson's disease and neuroinflammatory disorders |
| KR20200042906A (en) * | 2017-08-07 | 2020-04-24 | 고쿠리츠다이가쿠호진 히로시마다이가쿠 | New anthranilic acid compounds, and Pin1 inhibitors using the same, therapeutic agents for inflammatory diseases and therapeutic agents for cancer |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1118595A (en) | 1993-12-27 | 1996-03-13 | 卫材株式会社 | Anthranilic acid derivative |
| US5670504A (en) | 1995-02-23 | 1997-09-23 | Merck & Co. Inc. | 2,6-diaryl pyridazinones with immunosuppressant activity |
| US6083986A (en) | 1996-07-26 | 2000-07-04 | Icagen, Inc. | Potassium channel inhibitors |
| DK173062B1 (en) | 1996-10-11 | 1999-12-13 | Krueger As I | Process for removing dissolved metals and / or metalloids from an aqueous medium containing the same and with a solid |
| US5969017A (en) | 1996-10-31 | 1999-10-19 | Merck & Co., Inc. | Methods of treating or preventing cardiac arrhythmia |
| US5935945A (en) | 1996-10-31 | 1999-08-10 | Merck & Co., Inc. | Methods of treating or preventing cardiac arrhythmia |
| TW523506B (en) | 1996-12-18 | 2003-03-11 | Ono Pharmaceutical Co | Sulfonamide or carbamide derivatives and drugs containing the same as active ingredients |
| DK1095016T3 (en) | 1998-07-08 | 2006-03-13 | Sanofi Aventis Deutschland | Sulfur-substituted sulfonylaminocarboxylic acid N-arylamides, their preparation, their use and pharmaceutical compositions comprising them |
| EP1109544A4 (en) * | 1998-09-01 | 2004-10-27 | Bristol Myers Squibb Co | Potassium channel inhibitors and method |
| US6458845B1 (en) * | 1999-06-24 | 2002-10-01 | Smithkline Beecham Corporation | Macrophage scavenger receptor antagonists |
| DE19947457A1 (en) * | 1999-10-02 | 2001-04-05 | Aventis Pharma Gmbh | New 2'-aminomethyl-biphenyl-2-carboxamide derivatives, are potassium channel blockers especially useful for treating re-entry or supraventricular arrhythmia or atrial fibrillation or flutter |
| US6531495B1 (en) * | 1999-10-02 | 2003-03-11 | Aventis Pharma Deutschland Gmbh | 2′-Substituted 1,1′-biphenyl-2-carboxamides, processes for their preparation, their use as medicaments, and pharmaceutical preparations comprising them |
| DE10128331A1 (en) * | 2001-06-12 | 2002-12-19 | Aventis Pharma Gmbh | New 2-(heteroarylsulfonyl-amino)-benzamide derivatives, which are potassium ion channel blocking antiarrhythmic agents, useful for e.g. treating atrial fibrillation or flutter |
-
2001
- 2001-06-12 DE DE10128331A patent/DE10128331A1/en not_active Withdrawn
-
2002
- 2002-05-17 PE PE2002000419A patent/PE20021066A1/en not_active Application Discontinuation
- 2002-05-21 OA OA1200300333A patent/OA12631A/en unknown
- 2002-05-31 DK DK02745333T patent/DK1399423T3/en active
- 2002-05-31 RS YU97703A patent/RS97703A/en unknown
- 2002-05-31 PT PT02745333T patent/PT1399423E/en unknown
- 2002-05-31 HU HU0400159A patent/HUP0400159A3/en unknown
- 2002-05-31 EE EEP200300558A patent/EE05196B1/en not_active IP Right Cessation
- 2002-05-31 RU RU2004100302/04A patent/RU2293727C2/en not_active IP Right Cessation
- 2002-05-31 PL PL02364371A patent/PL364371A1/en not_active IP Right Cessation
- 2002-05-31 NZ NZ530081A patent/NZ530081A/en unknown
- 2002-05-31 IL IL15924702A patent/IL159247A0/en unknown
- 2002-05-31 CN CNB028118502A patent/CN1247544C/en not_active Expired - Fee Related
- 2002-05-31 DE DE50211213T patent/DE50211213D1/en not_active Expired - Lifetime
- 2002-05-31 JP JP2003503594A patent/JP4422477B2/en not_active Expired - Fee Related
- 2002-05-31 SK SK1522-2003A patent/SK15222003A3/en unknown
- 2002-05-31 EP EP02745333A patent/EP1399423B9/en not_active Expired - Lifetime
- 2002-05-31 AU AU2002316939A patent/AU2002316939B2/en not_active Ceased
- 2002-05-31 AT AT02745333T patent/ATE378318T1/en active
- 2002-05-31 CA CA2450076A patent/CA2450076C/en not_active Expired - Fee Related
- 2002-05-31 MX MXPA03010875A patent/MXPA03010875A/en active IP Right Grant
- 2002-05-31 UA UA2004010206A patent/UA75412C2/en unknown
- 2002-05-31 KR KR1020037016206A patent/KR100863924B1/en not_active IP Right Cessation
- 2002-05-31 BR BR0210374-5A patent/BR0210374A/en not_active Application Discontinuation
- 2002-05-31 ES ES02745333T patent/ES2295360T3/en not_active Expired - Lifetime
- 2002-05-31 WO PCT/EP2002/005956 patent/WO2002100825A2/en active IP Right Grant
- 2002-05-31 CZ CZ20033361A patent/CZ20033361A3/en unknown
- 2002-06-10 TW TW091112464A patent/TWI304400B/en not_active IP Right Cessation
- 2002-06-10 AR ARP020102178A patent/AR036045A1/en active IP Right Grant
- 2002-06-11 MY MYPI20022165A patent/MY138341A/en unknown
- 2002-06-12 US US10/166,595 patent/US6903216B2/en not_active Expired - Lifetime
-
2003
- 2003-07-08 TN TNPCT/EP2002/005956A patent/TNSN03134A1/en unknown
- 2003-10-31 ZA ZA200308520A patent/ZA200308520B/en unknown
- 2003-11-04 CR CR7140A patent/CR7140A/en not_active Application Discontinuation
- 2003-12-03 EC EC2003004883A patent/ECSP034883A/en unknown
- 2003-12-04 BG BG108415A patent/BG108415A/en unknown
- 2003-12-08 IL IL159247A patent/IL159247A/en not_active IP Right Cessation
- 2003-12-08 NO NO20035450A patent/NO20035450D0/en not_active Application Discontinuation
- 2003-12-10 MA MA27434A patent/MA27037A1/en unknown
- 2003-12-11 HR HR20031028A patent/HRP20031028A2/en not_active Application Discontinuation
- 2003-12-11 CO CO03108701A patent/CO5540283A2/en not_active Application Discontinuation
-
2004
- 2004-10-20 HK HK04108195A patent/HK1065316A1/en not_active IP Right Cessation
-
2005
- 2005-02-08 US US11/052,959 patent/US7235664B2/en not_active Expired - Lifetime
-
2008
- 2008-02-04 CY CY20081100143T patent/CY1107427T1/en unknown
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