AU2002232487A1 - Method for enhancing integrity of epithelium using retinoic acid - Google Patents
Method for enhancing integrity of epithelium using retinoic acidInfo
- Publication number
- AU2002232487A1 AU2002232487A1 AU2002232487A AU3248702A AU2002232487A1 AU 2002232487 A1 AU2002232487 A1 AU 2002232487A1 AU 2002232487 A AU2002232487 A AU 2002232487A AU 3248702 A AU3248702 A AU 3248702A AU 2002232487 A1 AU2002232487 A1 AU 2002232487A1
- Authority
- AU
- Australia
- Prior art keywords
- epithelium
- retinoic acid
- enhancing integrity
- integrity
- enhancing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 title 1
- 210000000981 epithelium Anatomy 0.000 title 1
- 229930002330 retinoic acid Natural products 0.000 title 1
- 229960001727 tretinoin Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25671300P | 2000-12-19 | 2000-12-19 | |
US60/256,713 | 2000-12-19 | ||
PCT/US2001/046499 WO2002049613A2 (en) | 2000-12-19 | 2001-12-03 | Method for enhancing integrity of epithelium using retinoic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002232487A1 true AU2002232487A1 (en) | 2002-07-01 |
Family
ID=22973298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002232487A Abandoned AU2002232487A1 (en) | 2000-12-19 | 2001-12-03 | Method for enhancing integrity of epithelium using retinoic acid |
Country Status (3)
Country | Link |
---|---|
US (2) | US6787131B2 (en) |
AU (1) | AU2002232487A1 (en) |
WO (1) | WO2002049613A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040122110A1 (en) * | 2002-09-06 | 2004-06-24 | Maccabee Mendy S. | Effect of vitamin A gel on paranasal sinus mucosal regeneration |
US20080027031A1 (en) * | 2006-03-08 | 2008-01-31 | Kinemed, Inc. | Retinoids and Related Compounds for the Treatment of Neuroinflammatory Conditions, Diseases and Disorders |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4136250A (en) | 1977-07-20 | 1979-01-23 | Ciba-Geigy Corporation | Polysiloxane hydrogels |
US4153641A (en) | 1977-07-25 | 1979-05-08 | Bausch & Lomb Incorporated | Polysiloxane composition and contact lens |
US4604479A (en) | 1981-12-04 | 1986-08-05 | Polymer Technology Corporation | Silicone-containing contact lens material and contact lenses made thereof |
US4826936A (en) | 1981-12-04 | 1989-05-02 | Polymer Technology Corp. | Silicone-containing contact lens material and contact lenses made thereof |
US4463149A (en) | 1982-03-29 | 1984-07-31 | Polymer Technology Corporation | Silicone-containing contact lens material and contact lenses made thereof |
US4826871A (en) * | 1985-03-13 | 1989-05-02 | Gressel Philip D | Topical ophthalmic compositions containing one or more retinoids |
US4996275A (en) | 1985-10-11 | 1991-02-26 | Polymer Technology Corporation | Fluorine containing polymeric compositions useful in contact lenses |
US4686267A (en) | 1985-10-11 | 1987-08-11 | Polymer Technology Corporation | Fluorine containing polymeric compositions useful in contact lenses |
US5032392A (en) * | 1986-09-04 | 1991-07-16 | Vision Pharmaceuticals | Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes |
US4740533A (en) | 1987-07-28 | 1988-04-26 | Ciba-Geigy Corporation | Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof |
US5270418A (en) | 1987-04-02 | 1993-12-14 | Bausch & Lomb Incorporated | Polymer compositions for contact lenses |
US5236969A (en) | 1987-04-02 | 1993-08-17 | Bausch & Lomb Incorporated | Polymer compositions for contact lenses |
US5006622A (en) | 1987-04-02 | 1991-04-09 | Bausch & Lomb Incorporated | Polymer compositions for contact lenses |
US4910277A (en) | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
US5070215A (en) | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
US5034461A (en) | 1989-06-07 | 1991-07-23 | Bausch & Lomb Incorporated | Novel prepolymers useful in biomedical devices |
US5177168A (en) | 1989-10-17 | 1993-01-05 | Polymer Technology Corp. | Polymeric compositions useful in oxygen permeable contact lenses |
US5032658A (en) | 1989-10-17 | 1991-07-16 | Polymer Technology Corporation | Polymeric compositions useful in oxygen permeable contact lenses |
JP3256997B2 (en) * | 1990-08-30 | 2002-02-18 | 千寿製薬株式会社 | Stable aqueous formulation |
US5177165A (en) | 1990-11-27 | 1993-01-05 | Bausch & Lomb Incorporated | Surface-active macromonomers |
US5219965A (en) | 1990-11-27 | 1993-06-15 | Bausch & Lomb Incorporated | Surface modification of polymer objects |
NZ242358A (en) * | 1991-05-10 | 1994-03-25 | Allergan Inc | Use of thiol compounds to inhibit deposits on a contact lens |
US5310779A (en) | 1991-11-05 | 1994-05-10 | Bausch & Lomb Incorporated | UV curable crosslinking agents useful in copolymerization |
US5358995A (en) | 1992-05-15 | 1994-10-25 | Bausch & Lomb Incorporated | Surface wettable silicone hydrogels |
US5260000A (en) | 1992-08-03 | 1993-11-09 | Bausch & Lomb Incorporated | Process for making silicone containing hydrogel lenses |
US5298533A (en) | 1992-12-02 | 1994-03-29 | Bausch & Lomb Incorporated | Polymer compositions for contact lenses |
US5336797A (en) | 1992-12-30 | 1994-08-09 | Bausch & Lomb Incorporated | Siloxane macromonomers |
US5321108A (en) | 1993-02-12 | 1994-06-14 | Bausch & Lomb Incorporated | Fluorosilicone hydrogels |
US5346976A (en) | 1993-03-29 | 1994-09-13 | Polymer Technology Corporation | Itaconate copolymeric compositions for contact lenses |
US5616757A (en) | 1993-04-08 | 1997-04-01 | Bausch & Lomb Incorporated | Organosilicon-containing materials useful for biomedical devices |
EP0711147A1 (en) * | 1993-07-28 | 1996-05-15 | Insite Vision Incorporated | Suspensions for delivery of medicament |
US5451651A (en) | 1993-12-17 | 1995-09-19 | Bausch & Lomb Incorporated | Urea and urethane monomers for contact lens materials |
AU1373195A (en) | 1993-12-21 | 1995-07-10 | Bausch & Lomb Incorporated | Method for increasing hydrophilicity of contact lenses |
WO1996003666A1 (en) | 1994-07-26 | 1996-02-08 | Bausch & Lomb Incorporated | Method of polymerizing methacrylate-based compositions |
AU3627695A (en) * | 1994-09-30 | 1996-04-26 | Alcon Laboratories, Inc. | Use of retinoid glycosides in topical pharmaceutical compositions |
US5824719A (en) | 1995-06-07 | 1998-10-20 | Bausch & Lomb Incorporated | Polymer compositions for contact lenses |
CN1070494C (en) | 1995-12-07 | 2001-09-05 | 博士伦公司 | Monomeric units useful for reducing modulus of low water polymeric silicone composition |
AU713509B2 (en) | 1995-12-07 | 1999-12-02 | Bausch & Lomb Incorporated | Monomeric units useful for reducing the modulus of silicone hydrogels |
US5858937A (en) | 1996-02-28 | 1999-01-12 | Bausch & Lomb Incorporated | Treatment of contact lenses with aqueous solution including phosphonic compounds |
US5708094A (en) | 1996-12-17 | 1998-01-13 | Bausch & Lomb Incorporated | Polybutadiene-based compositions for contact lenses |
JP3090125B2 (en) * | 1997-08-26 | 2000-09-18 | 千寿製薬株式会社 | Ophthalmic composition for soft contact lens, method for enhancing wettability of soft contact lens, and method for suppressing adsorption of terpenoid |
US5981669A (en) | 1997-12-29 | 1999-11-09 | Bausch & Lomb Incorporated | Silicone-containing prepolymers and low water materials |
US5969076A (en) | 1998-05-15 | 1999-10-19 | Bausch & Lomb Incorporated | Thermoplastic silicone-containing hydrogels |
US5945465A (en) | 1998-05-15 | 1999-08-31 | Bausch & Lomb Incorporated | Method for polymerizing contact lenses having UV absorbing properties |
US5914355A (en) | 1998-05-15 | 1999-06-22 | Bausch & Lomb Incorporated | Method for making contact lenses having UV absorbing properties |
US5981675A (en) | 1998-12-07 | 1999-11-09 | Bausch & Lomb Incorporated | Silicone-containing macromonomers and low water materials |
JP2001158734A (en) * | 1999-12-02 | 2001-06-12 | Lion Corp | Composition for ophthalmology and method for inhibiting adsorption to soft contact lens |
-
2001
- 2001-12-03 WO PCT/US2001/046499 patent/WO2002049613A2/en not_active Application Discontinuation
- 2001-12-03 AU AU2002232487A patent/AU2002232487A1/en not_active Abandoned
- 2001-12-17 US US10/023,351 patent/US6787131B2/en not_active Expired - Lifetime
-
2004
- 2004-06-16 US US10/869,432 patent/US7087222B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6787131B2 (en) | 2004-09-07 |
US20020115720A1 (en) | 2002-08-22 |
WO2002049613A3 (en) | 2003-01-16 |
US7087222B2 (en) | 2006-08-08 |
US20040225110A1 (en) | 2004-11-11 |
WO2002049613A2 (en) | 2002-06-27 |
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