AU2001233918A1 - Pyridinylimidazoles - Google Patents

Pyridinylimidazoles

Info

Publication number
AU2001233918A1
AU2001233918A1 AU2001233918A AU2001233918A AU2001233918A1 AU 2001233918 A1 AU2001233918 A1 AU 2001233918A1 AU 2001233918 A AU2001233918 A AU 2001233918A AU 2001233918 A AU2001233918 A AU 2001233918A AU 2001233918 A1 AU2001233918 A1 AU 2001233918A1
Authority
AU
Australia
Prior art keywords
pyridinylimidazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2001233918A
Other versions
AU2001233918B2 (en
Inventor
Laramie Mary Gaster
Michael Stewart Hadley
John David Harling
Frank Peter Harrington
Jag Paul Heer
Thomas Daniel Heightman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB0004053A priority Critical patent/GB0004053D0/en
Priority to GB0004053.5 priority
Priority to GB0015902A priority patent/GB0015902D0/en
Priority to GB0015902.0 priority
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Priority to PCT/GB2001/000736 priority patent/WO2001062756A1/en
Publication of AU2001233918A1 publication Critical patent/AU2001233918A1/en
Application granted granted Critical
Publication of AU2001233918B2 publication Critical patent/AU2001233918B2/en
Application status is Ceased legal-status Critical
Anticipated expiration legal-status Critical

Links

AU2001233918A 2000-02-21 2001-02-21 Pyridinylimidazoles Ceased AU2001233918B2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB0004053A GB0004053D0 (en) 2000-02-21 2000-02-21 Compounds
GB0004053.5 2000-02-21
GB0015902A GB0015902D0 (en) 2000-06-28 2000-06-28 Compounds
GB0015902.0 2000-06-28
PCT/GB2001/000736 WO2001062756A1 (en) 2000-02-21 2001-02-21 Pyridinylimidazoles

Publications (2)

Publication Number Publication Date
AU2001233918A1 true AU2001233918A1 (en) 2001-11-15
AU2001233918B2 AU2001233918B2 (en) 2004-06-24

Family

ID=26243690

Family Applications (2)

Application Number Title Priority Date Filing Date
AU3391801A Pending AU3391801A (en) 2000-02-21 2001-02-21 Pyridinylimidazoles
AU2001233918A Ceased AU2001233918B2 (en) 2000-02-21 2001-02-21 Pyridinylimidazoles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU3391801A Pending AU3391801A (en) 2000-02-21 2001-02-21 Pyridinylimidazoles

Country Status (17)

Country Link
US (2) US20030166633A1 (en)
EP (1) EP1257543A1 (en)
JP (1) JP2003524010A (en)
CN (1) CN1404478A (en)
AR (1) AR029803A1 (en)
AU (2) AU3391801A (en)
BR (1) BR0108437A (en)
CA (1) CA2401036A1 (en)
CO (1) CO5271680A1 (en)
CZ (1) CZ20022852A3 (en)
HU (1) HU0204514A3 (en)
IL (1) IL151319D0 (en)
MX (1) MXPA02008082A (en)
NO (1) NO20023953L (en)
NZ (1) NZ520753A (en)
PL (1) PL357420A1 (en)
WO (1) WO2001062756A1 (en)

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GB0127433D0 (en) * 2001-11-15 2002-01-09 Smithkline Beecham Corp Compounds
AU2003224335A1 (en) * 2002-05-15 2003-12-02 Smithkline Beecham Corporation Benzoxazine and benzoxazinone substituted triazoles
US20040146509A1 (en) * 2002-07-25 2004-07-29 Zhihe Li Methods for improvement of lung function using TGF-beta inhibitors
AU2003256783A1 (en) * 2002-07-25 2004-02-16 Scios, Inc. METHODS FOR IMPROVEMENT OF LUNG FUNCTION USING TGF-Beta INHIBITORS
US20060135517A1 (en) * 2002-09-06 2006-06-22 Wen-Cherng Lee Imidazolopyridines and methods of making and using the same
KR20050057235A (en) 2002-09-06 2005-06-16 바이오겐 아이덱 엠에이 인코포레이티드 Pyrazolopyridines and methods of making and using the same
EP1542685A1 (en) 2002-09-18 2005-06-22 Pfizer Products Inc. Triazole derivatives as transforming growth factor (tgf) inhibitors
AP200503263A0 (en) 2002-09-18 2005-03-31 Pfizer Prod Inc Pyrazole derivatives as transforming growth factor(TGF) inhibitors.
KR20050057415A (en) 2002-09-18 2005-06-16 화이자 프로덕츠 인코포레이티드 Novel triazole and oxazole compounds as transforming growth factor (tgf) inhibitor
EP1542995A1 (en) 2002-09-18 2005-06-22 Pfizer Products Inc. Novel isothiazole and isoxazole compounds as transforming growth factor (tgf) inhibitors
AU2003263404A1 (en) 2002-09-18 2004-04-08 Pfizer Products Inc. Novel imidazole compounds as transforming growth factor (tgf) inhibitors
PA8595001A1 (en) 2003-03-04 2004-09-28 Pfizer Prod Inc New heteroaromatic compounds are condensates inhibitors transforante factor (TGF)
WO2005092894A1 (en) * 2004-03-01 2005-10-06 Eli Lilly And Company Fused pyrazole derivatives as tgf-beta signal transduction inhibitors for the treatment of fibrosis and neoplasms
JP4853284B2 (en) 2004-03-05 2012-01-11 大正製薬株式会社 Thiazole derivative
KR100749566B1 (en) * 2004-04-21 2007-08-16 에스케이케미칼주식회사 2-PYRIDYL SUBSTITUTED IMIDAZOLES AS ALK5 and/or ALK4 INHIBITORS
US20080319012A1 (en) * 2004-04-21 2008-12-25 In2Gen Co., Ltd. 2-Pyridyl substituted imidazoles as ALK5 and/or ALK4 inhibitors
US7453002B2 (en) 2004-06-15 2008-11-18 Bristol-Myers Squibb Company Five-membered heterocycles useful as serine protease inhibitors
EP1798229A4 (en) * 2004-09-07 2009-07-29 Sankyo Co Substituted biphenyl derivative
EP1910337A2 (en) * 2005-06-24 2008-04-16 Genelabs Technologies, Inc. Heteroaryl derivatives for treating viruses
KR100694181B1 (en) * 2005-11-25 2007-03-06 연세대학교 산학협력단 Compounds inducing differentiation of myoblasts or muscle fibers into neuron cells, pharmaceutical composition including said compounds, a method for inducing neuron differentiation and a screening method for identifying additional compound useful for inducing neuron differentiation
WO2008071605A2 (en) * 2006-12-15 2008-06-19 F. Hoffmann-La Roche Ag Methods of treating inflammatory diseases
GB0715087D0 (en) 2007-08-03 2007-09-12 Summit Corp Plc Drug combinations for the treatment of duchenne muscular dystrophy
MX2009012558A (en) 2007-08-03 2010-04-21 Biomarin Iga Ltd Drug combinations for the treatment of duchenne muscular dystrophy.
WO2009047163A1 (en) * 2007-10-10 2009-04-16 F. Hoffmann-La Roche Ag Methods of treating inflammatory diseases
US8865732B2 (en) 2008-03-21 2014-10-21 Novartis Ag Heterocyclic compounds and uses thereof
EA201001456A1 (en) * 2008-03-21 2011-06-30 Новартис Аг New heterocyclic compounds and their application
US8586581B2 (en) 2009-12-17 2013-11-19 Hoffmann-La Roche Inc Ethynyl compounds useful for treatment of CNS disorders
US8513222B2 (en) 2010-06-29 2013-08-20 EWHA University—Industry Collaboration Foundation Methods of treating fibrosis, cancer and vascular injuries
US8080568B1 (en) * 2010-06-29 2011-12-20 Ewha University - Industry Collaboration Foundation 2-pyridyl substituted imidazoles as therapeutic ALK5 and/or ALK4 inhibitors
USRE47141E1 (en) 2010-06-29 2018-11-27 EWHA University—Industry Collaboration Foundation Methods of treating fibrosis, cancer and vascular injuries
TWI410425B (en) * 2010-12-03 2013-10-01 Lilly Co Eli Oxazolo[5,4-b]pyridin-5-yl compounds
KR101938368B1 (en) 2011-07-13 2019-01-14 주식회사 티움바이오 2-pyridyl substituted imidazoles as alk5 and/or alk4 inhibitors
NZ621520A (en) * 2011-07-29 2016-05-27 Karyopharm Therapeutics Inc Nuclear transport modulators and uses thereof
JP6005740B2 (en) 2011-07-29 2016-10-12 カリオファーム セラピューティクス,インコーポレイテッド Hydrazide-containing nuclear transport regulators and uses thereof
NZ702663A (en) 2012-05-09 2017-03-31 Karyopharm Therapeutics Inc Nuclear transport modulators and uses thereof
DK2855665T3 (en) 2012-05-30 2019-11-04 Univ Cornell Provision of functional and resistant endotel cells from human amnion fluid derivated cells
EP2880053A4 (en) 2012-08-01 2016-03-09 Elizabeth Mcnally Mitigating tissue damage and fibrosis via latent transforming growth factor beta binding protein (ltbp4)
JP2016508726A (en) 2013-02-22 2016-03-24 セルラー ダイナミクス インターナショナル, インコーポレイテッド Production of hepatocytes via forward programming with combined genetic and chemical manipulation
US9242969B2 (en) 2013-03-14 2016-01-26 Novartis Ag Biaryl amide compounds as kinase inhibitors
EP2968278B8 (en) 2013-03-15 2019-05-22 Karyopharm Therapeutics Inc. Methods of promoting wound healing using crm1 inhibitors
EP3492455A1 (en) 2013-06-21 2019-06-05 Karyopharm Therapeutics Inc. 1,2,4-triazoles as nuclear transport modulators and use in the treatment of specific forms of cancer
WO2015164228A1 (en) 2014-04-21 2015-10-29 Cellular Dynamics International, Inc. Hepatocyte production via forward programming by combined genetic and chemical engineering
ES2713452T3 (en) 2014-04-22 2019-05-21 Univ Basel Manufacturing process for triazine, pyrimidine and pyridine derivatives
UY36294A (en) 2014-09-12 2016-04-29 Novartis Ag Compounds and compositions as kinase inhibitors
WO2018132279A1 (en) * 2017-01-05 2018-07-19 Bristol-Myers Squibb Company Tgf beta receptor antagonists

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH561718A5 (en) * 1971-05-10 1975-05-15 Ciba Geigy Ag
MX9300141A (en) * 1992-01-13 1994-07-29 Smithkline Beecham Corp Imidazole compounds of novel, process for their preparation and pharmaceutical compositions containing it.
AU7629594A (en) * 1993-07-21 1995-02-20 Smithkline Beecham Corporation Imidazoles for treating cytokine mediated disease
US5656644A (en) * 1994-07-20 1997-08-12 Smithkline Beecham Corporation Pyridyl imidazoles
JPH09124640A (en) * 1995-08-25 1997-05-13 Nippon Soda Co Ltd Pyridylimidazole compound, production thereof and fungicide for agricultural and horticultural use
KR20010014288A (en) * 1997-06-30 2001-02-26 오르토-맥네일 파마슈티칼, 인코퍼레이티드 2-Substituted imidazoles useful in the treatment of inflammatory diseases
US6207687B1 (en) * 1998-07-31 2001-03-27 Merck & Co., Inc. Substituted imidazoles having cytokine inhibitory activity

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