ATE474498T1 - Optisches biopsiesystem - Google Patents

Optisches biopsiesystem

Info

Publication number
ATE474498T1
ATE474498T1 AT08016179T AT08016179T ATE474498T1 AT E474498 T1 ATE474498 T1 AT E474498T1 AT 08016179 T AT08016179 T AT 08016179T AT 08016179 T AT08016179 T AT 08016179T AT E474498 T1 ATE474498 T1 AT E474498T1
Authority
AT
Austria
Prior art keywords
tissue
diagnosis
fluorescence
optical biopsy
treatment
Prior art date
Application number
AT08016179T
Other languages
English (en)
Inventor
Scott R Wilson
Chester E Sievert Jr
Brian T Mcmahon
Ronald Zimmermann
Robert A Palme
John G Yager
David R Walsh
Original Assignee
Spectrascience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spectrascience Inc filed Critical Spectrascience Inc
Application granted granted Critical
Publication of ATE474498T1 publication Critical patent/ATE474498T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/06—Biopsy forceps, e.g. with cup-shaped jaws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/042—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by a proximal camera, e.g. a CCD camera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
  • Eye Examination Apparatus (AREA)
  • Telescopes (AREA)
  • Gyroscopes (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
AT08016179T 1998-03-09 1999-03-09 Optisches biopsiesystem ATE474498T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/037,722 US6174291B1 (en) 1998-03-09 1998-03-09 Optical biopsy system and methods for tissue diagnosis

Publications (1)

Publication Number Publication Date
ATE474498T1 true ATE474498T1 (de) 2010-08-15

Family

ID=21895938

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99913840T ATE412363T1 (de) 1998-03-09 1999-03-09 Optisches biopsiesystem zur gewebediagnostik
AT08016179T ATE474498T1 (de) 1998-03-09 1999-03-09 Optisches biopsiesystem

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT99913840T ATE412363T1 (de) 1998-03-09 1999-03-09 Optisches biopsiesystem zur gewebediagnostik

Country Status (7)

Country Link
US (1) US6174291B1 (de)
EP (2) EP2018824B1 (de)
JP (2) JP4477230B2 (de)
AT (2) ATE412363T1 (de)
CA (1) CA2322768C (de)
DE (2) DE69942624D1 (de)
WO (1) WO1999045838A1 (de)

Families Citing this family (300)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7236815B2 (en) * 1995-03-14 2007-06-26 The Board Of Regents Of The University Of Texas System Method for probabilistically classifying tissue in vitro and in vivo using fluorescence spectroscopy
US20080146965A1 (en) * 2003-08-11 2008-06-19 Salvatore Privitera Surgical Device for The Collection of Soft Tissue
IL143258A0 (en) * 2001-05-20 2002-04-21 Given Imaging Ltd A method for in vivo imaging of the gastrointestinal tract in unmodified conditions
JP2001017379A (ja) * 1999-07-09 2001-01-23 Fuji Photo Film Co Ltd 蛍光診断装置
DE60016533T2 (de) * 1999-09-29 2005-12-15 Fuji Photo Film Co. Ltd., Minamiashigara Vorrichtung zur Erfassung eines Fluoreszenzbildes
AU1572401A (en) * 1999-11-05 2001-06-06 Spectrx, Inc. Multi-modal optical tissue diagnostic system
US8888688B2 (en) 2000-04-03 2014-11-18 Intuitive Surgical Operations, Inc. Connector device for a controllable instrument
US6858005B2 (en) * 2000-04-03 2005-02-22 Neo Guide Systems, Inc. Tendon-driven endoscope and methods of insertion
US8517923B2 (en) 2000-04-03 2013-08-27 Intuitive Surgical Operations, Inc. Apparatus and methods for facilitating treatment of tissue via improved delivery of energy based and non-energy based modalities
US6984203B2 (en) * 2000-04-03 2006-01-10 Neoguide Systems, Inc. Endoscope with adjacently positioned guiding apparatus
US6610007B2 (en) 2000-04-03 2003-08-26 Neoguide Systems, Inc. Steerable segmented endoscope and method of insertion
US6468203B2 (en) 2000-04-03 2002-10-22 Neoguide Systems, Inc. Steerable endoscope and improved method of insertion
WO2005018428A2 (en) * 2000-04-03 2005-03-03 Neoguide Systems, Inc. Activated polymer articulated instruments and methods of insertion
US6678398B2 (en) * 2000-09-18 2004-01-13 Sti Medical Systems, Inc. Dual mode real-time screening and rapid full-area, selective-spectral, remote imaging and analysis device and process
AU2002230842A1 (en) 2000-10-30 2002-05-15 The General Hospital Corporation Optical methods and systems for tissue analysis
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
GB0030310D0 (en) * 2000-12-13 2001-01-24 Medical Res Council Apparatus and method for imaging a histological sample
JP3961765B2 (ja) * 2000-12-28 2007-08-22 ペンタックス株式会社 電子内視鏡システム
US9897538B2 (en) 2001-04-30 2018-02-20 The General Hospital Corporation Method and apparatus for improving image clarity and sensitivity in optical coherence tomography using dynamic feedback to control focal properties and coherence gating
WO2002088705A2 (en) 2001-05-01 2002-11-07 The General Hospital Corporation Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties
US6814739B2 (en) 2001-05-18 2004-11-09 U.S. Endoscopy Group, Inc. Retrieval device
US6796710B2 (en) * 2001-06-08 2004-09-28 Ethicon Endo-Surgery, Inc. System and method of measuring and controlling temperature of optical fiber tip in a laser system
EP1418833B1 (de) * 2001-06-18 2008-08-13 Given Imaging Ltd. Schluckbare in vivo-erfassungskapsel mit einer starre und flexible abschnitte aufweisenden leiterplatte
US8423110B2 (en) * 2002-01-09 2013-04-16 Boston Scientific Scimed, Inc. Imaging device and related methods
AU2002360767A1 (en) 2002-01-09 2003-07-30 Neoguide Systems, Inc Apparatus and method for spectroscopic examination of the colon
CN1764416A (zh) 2002-01-09 2006-04-26 新引导系统公司 用于内窥镜结肠切除术的设备和方法
US7355716B2 (en) * 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
US7826883B2 (en) * 2002-04-23 2010-11-02 Devicor Medical Products, Inc. Localization mechanism for an MRI compatible biopsy device
US7769426B2 (en) * 2002-04-23 2010-08-03 Ethicon Endo-Surgery, Inc. Method for using an MRI compatible biopsy device with detachable probe
US20030199753A1 (en) * 2002-04-23 2003-10-23 Ethicon Endo-Surgery MRI compatible biopsy device with detachable probe
US20110201924A1 (en) * 2002-04-30 2011-08-18 The General Hospital Corporation Method and Apparatus for Improving Image Clarity and Sensitivity in Optical Tomography Using Dynamic Feedback to Control Focal Properties and Coherence Gating
US7662094B2 (en) * 2002-05-14 2010-02-16 Given Imaging Ltd. Optical head assembly with dome, and device for use thereof
DE60332944D1 (de) * 2002-08-13 2010-07-22 Given Imaging Ltd System für die probenahme und analyse in vivo
AU2003264858A1 (en) * 2002-09-30 2004-04-19 Given Imaging Ltd. Reduced size imaging device
US20040064053A1 (en) * 2002-09-30 2004-04-01 Chang Sung K. Diagnostic fluorescence and reflectance
WO2004028335A2 (en) * 2002-09-30 2004-04-08 Given Imaging Ltd. In-vivo sensing system
DE10246521B4 (de) * 2002-10-05 2005-11-10 Karl Storz Gmbh & Co. Kg Endoskop
WO2004036803A2 (en) * 2002-10-15 2004-04-29 Given Imaging Ltd. Device, system and method for transfer of signals to a moving device
US7438692B2 (en) * 2002-10-18 2008-10-21 Mark Tsonton Localization mechanism for an MRI compatible biopsy device
US20080045788A1 (en) * 2002-11-27 2008-02-21 Zvika Gilad Method and device of imaging with an in vivo imager
US6980573B2 (en) * 2002-12-09 2005-12-27 Infraredx, Inc. Tunable spectroscopic source with power stability and method of operation
EP1587407B1 (de) * 2002-12-26 2012-03-07 Given Imaging Ltd. Immobilisierbare in-vivo messvorrichtung
EP1576530A4 (de) * 2002-12-26 2009-03-25 Given Imaging Ltd In-vivo abbildungsvorrichtung und herstellungsverfahren dafür
US7643153B2 (en) * 2003-01-24 2010-01-05 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
EP2319405B1 (de) * 2003-01-24 2013-09-18 The General Hospital Corporation System und Verfahren zur Gewebeidentifizierung mittels Interferometrie mit niedriger Kohärenz
US6912050B2 (en) * 2003-02-03 2005-06-28 Hach Company Phase shift measurement for luminescent light
US8882657B2 (en) 2003-03-07 2014-11-11 Intuitive Surgical Operations, Inc. Instrument having radio frequency identification systems and methods for use
EP2436307B1 (de) 2003-03-31 2015-10-21 The General Hospital Corporation Fleckenreduzierung bei der optischen Kohärenztomografie durch pfadlängencodierte Winkelmischung
US7102758B2 (en) 2003-05-06 2006-09-05 Duke University Fourier domain low-coherence interferometry for light scattering spectroscopy apparatus and method
KR20130138867A (ko) * 2003-06-06 2013-12-19 더 제너럴 하스피탈 코포레이션 파장 동조 소스용 방법 및 장치
US20040267121A1 (en) * 2003-06-12 2004-12-30 Sarvazyan Armen P. Device and method for biopsy guidance using a tactile breast imager
JP4306380B2 (ja) * 2003-09-10 2009-07-29 株式会社日立メディコ 医用画像表示方法及び装置
US20050059894A1 (en) * 2003-09-16 2005-03-17 Haishan Zeng Automated endoscopy device, diagnostic method, and uses
US7908690B2 (en) * 2003-09-30 2011-03-22 Sentinelle Medical, Inc. Supine patient support for medical imaging
US7379769B2 (en) * 2003-09-30 2008-05-27 Sunnybrook Health Sciences Center Hybrid imaging method to monitor medical device delivery and patient support for use in the method
US20080077005A1 (en) * 2004-08-12 2008-03-27 Piron Cameron A System and Method for Multimodality Breast Imaging
US7970452B2 (en) * 2003-09-30 2011-06-28 Hologic, Inc. Open architecture imaging apparatus and coil system for magnetic resonance imaging
KR101384553B1 (ko) 2003-10-27 2014-04-11 더 제너럴 하스피탈 코포레이션 주파수 영역 간섭법을 이용하여 광 영상화를 수행하는 방법 및 장치
WO2005054780A1 (en) * 2003-11-28 2005-06-16 The General Hospital Corporation Method and apparatus for three-dimensional spectrally encoded imaging
WO2005052558A1 (en) * 2003-11-28 2005-06-09 Bc Cancer Agency Multimodal detection of tissue abnormalities based on raman and background fluorescence spectroscopy
US20050171436A1 (en) * 2004-01-09 2005-08-04 Clarke Richard H. Raman spectroscopy for monitoring drug-eluting medical devices
US11832793B2 (en) 2004-03-23 2023-12-05 Boston Scientific Scimed, Inc. Vivo visualization system
US7922654B2 (en) * 2004-08-09 2011-04-12 Boston Scientific Scimed, Inc. Fiber optic imaging catheter
ES2409160T3 (es) 2004-03-23 2013-06-25 Boston Scientific Limited Sistema de visualización in vivo
US20060155178A1 (en) * 2004-03-26 2006-07-13 Vadim Backman Multi-dimensional elastic light scattering
US20050250091A1 (en) * 2004-05-05 2005-11-10 Chemlmage Corporation Raman molecular imaging for detection of bladder cancer
US20060281068A1 (en) * 2005-06-09 2006-12-14 Chemimage Corp. Cytological methods for detecting a disease condition such as malignancy by Raman spectroscopic imaging
US7697576B2 (en) 2004-05-05 2010-04-13 Chem Image Corporation Cytological analysis by raman spectroscopic imaging
US8932233B2 (en) 2004-05-21 2015-01-13 Devicor Medical Products, Inc. MRI biopsy device
US9638770B2 (en) * 2004-05-21 2017-05-02 Devicor Medical Products, Inc. MRI biopsy apparatus incorporating an imageable penetrating portion
US7708751B2 (en) * 2004-05-21 2010-05-04 Ethicon Endo-Surgery, Inc. MRI biopsy device
US8018598B2 (en) 2004-05-29 2011-09-13 The General Hospital Corporation Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (OCT) imaging
WO2005122878A1 (en) * 2004-06-15 2005-12-29 Umc Utrecht Holding B.V. Method and device for the detection of cancer
US7643865B2 (en) * 2004-06-30 2010-01-05 Given Imaging Ltd. Autonomous in-vivo device
US7596403B2 (en) 2004-06-30 2009-09-29 Given Imaging Ltd. System and method for determining path lengths through a body lumen
US20060015013A1 (en) * 2004-06-30 2006-01-19 Zvika Gilad Device and method for in vivo illumination
WO2006005075A2 (en) * 2004-06-30 2006-01-12 Amir Belson Apparatus and methods for capsule endoscopy of the esophagus
WO2006014392A1 (en) 2004-07-02 2006-02-09 The General Hospital Corporation Endoscopic imaging probe comprising dual clad fibre
KR101332222B1 (ko) 2004-08-06 2013-11-22 더 제너럴 하스피탈 코포레이션 광간섭 단층촬영법을 이용해서 샘플 내에서 적어도 하나의 위치를 결정하는 방법, 시스템 및 그 방법을 구현하기 위한 소프트웨어가 저장되어 컴퓨터로 판독 가능한 매체
EP1793730B1 (de) * 2004-08-24 2011-12-28 The General Hospital Corporation Verfahren, system und software-anordnung zur bestimmung des elastizitätsmoduls
JP5324095B2 (ja) * 2004-08-24 2013-10-23 ザ ジェネラル ホスピタル コーポレイション 血管セグメントを画像化する方法および装置
KR101269455B1 (ko) 2004-09-10 2013-05-30 더 제너럴 하스피탈 코포레이션 광 간섭 영상화를 위한 시스템 및 방법
KR101257100B1 (ko) 2004-09-29 2013-04-22 더 제너럴 하스피탈 코포레이션 광 간섭 영상화 시스템 및 방법
JP2008514363A (ja) * 2004-09-30 2008-05-08 ボストン サイエンティフィック リミテッド 電気外科用途において使用するための多機能内視鏡システム
JP2008514343A (ja) * 2004-09-30 2008-05-08 ジラ バイオテクノロジー・インク 異常粘膜組織を検出し、異常粘膜組織の更なる評価を支援するための光指定法
JP5175101B2 (ja) * 2004-10-29 2013-04-03 ザ ジェネラル ホスピタル コーポレイション 偏光感応性光コヒーレンストモグラフィを用いて偏光非解消の偏光パラメータを測定するジョーンズ行列に基づく解析を行うシステム及び方法
AU2005229684A1 (en) * 2004-11-04 2006-05-18 Given Imaging Ltd Apparatus and method for receiving device selection and combining
US7417740B2 (en) * 2004-11-12 2008-08-26 Medeikon Corporation Single trace multi-channel low coherence interferometric sensor
US20060229515A1 (en) * 2004-11-17 2006-10-12 The Regents Of The University Of California Fiber optic evaluation of tissue modification
US10413188B2 (en) * 2004-11-17 2019-09-17 Lawrence Livermore National Security, Llc Assessment of tissue or lesion depth using temporally resolved light scattering spectroscopy
CA2588390C (en) * 2004-11-17 2016-06-07 Biosense Webster, Inc. Apparatus for real time evaluation of tissue ablation
WO2006058049A1 (en) 2004-11-24 2006-06-01 The General Hospital Corporation Common-path interferometer for endoscopic oct
JP2008521516A (ja) 2004-11-29 2008-06-26 ザ ジェネラル ホスピタル コーポレイション サンプル上の複数の地点を同時に照射し検出することによって光学画像生成を実行する構成、装置、内視鏡、カテーテル、及び方法
US7854705B2 (en) * 2004-12-16 2010-12-21 Olga Pawluczyk Ex vivo verification of biopsy tissue samples
JP4619803B2 (ja) 2005-01-26 2011-01-26 富士フイルム株式会社 蛍光断層画像取得装置
US7524671B2 (en) * 2005-01-27 2009-04-28 Prescient Medical, Inc. Handheld raman blood analyzer
US7651851B2 (en) * 2005-01-27 2010-01-26 Prescient Medical, Inc. Handheld Raman body fluid analyzer
US7688440B2 (en) 2005-01-27 2010-03-30 Prescient Medical, Inc. Raman spectroscopic test strip systems
US20060241385A1 (en) * 2005-04-12 2006-10-26 Ethicon Endo-Surgery, Inc. Guided disposable fiducial for breast biopsy localization fixture
US20060235458A1 (en) * 2005-04-15 2006-10-19 Amir Belson Instruments having an external working channel
CN101495025B (zh) 2005-04-15 2013-09-04 塞基森斯公司 用于检测组织特性具有传感器的外科器械，和使用所述器械的系统
JP2008538612A (ja) * 2005-04-22 2008-10-30 ザ ジェネラル ホスピタル コーポレイション スペクトルドメイン偏光感受型光コヒーレンストモグラフィを提供することの可能な構成、システム、及び方法
US8351665B2 (en) * 2005-04-28 2013-01-08 The General Hospital Corporation Systems, processes and software arrangements for evaluating information associated with an anatomical structure by an optical coherence ranging technique
WO2006119166A2 (en) 2005-04-29 2006-11-09 The Regents Of The University Of Colorado Multi-excitation diagnostic systems and methods for classification of tissue
US20070009935A1 (en) * 2005-05-13 2007-01-11 The General Hospital Corporation Arrangements, systems and methods capable of providing spectral-domain optical coherence reflectometry for a sensitive detection of chemical and biological sample
US7859679B2 (en) * 2005-05-31 2010-12-28 The General Hospital Corporation System, method and arrangement which can use spectral encoding heterodyne interferometry techniques for imaging
US8253936B2 (en) * 2008-08-08 2012-08-28 Chemimage Corporation Raman characterization of transplant tissue
EP2207008A1 (de) * 2005-08-09 2010-07-14 The General Hospital Corporation Gerät und Verfahren zur Durchführung von polarisationsbasierter Quadraturdemulation bei optischer Kohärenztomographie
US20070049833A1 (en) * 2005-08-16 2007-03-01 The General Hospital Corporation Arrangements and methods for imaging in vessels
WO2007033379A2 (en) * 2005-09-14 2007-03-22 Neoguide Systems, Inc. Methods and apparatus for performing transluminal and other procedures
DK1937137T3 (da) 2005-09-29 2022-08-29 Massachusetts Gen Hospital Fremgangsmåde og indretning til optisk billeddannelse via spektral kodning
ES2402796T3 (es) * 2005-10-11 2013-05-09 Duke University Sistemas y método para interferometría endoscópica de baja coherencia resuelta en ángulo
US8537366B2 (en) * 2005-10-11 2013-09-17 Duke University Systems and methods for endoscopic angle-resolved low coherence interferometry
EP1945094B1 (de) * 2005-10-14 2018-09-05 The General Hospital Corporation Spektral- und frequenz-kodierte fluoreszenz-darstellung
US7901441B2 (en) 2005-10-18 2011-03-08 Boston Scientific Scimed, Inc. Method of using an imaging catheter to conduct photodynamic procedures
WO2007050683A2 (en) * 2005-10-24 2007-05-03 Spectrascience, Inc. System and method for non-endoscopic optical biopsy detection of diseased tissue
US9314164B2 (en) 2005-10-27 2016-04-19 Northwestern University Method of using the detection of early increase in microvascular blood content to distinguish between adenomatous and hyperplastic polyps
US20090203977A1 (en) * 2005-10-27 2009-08-13 Vadim Backman Method of screening for cancer using parameters obtained by the detection of early increase in microvascular blood content
JP2009516574A (ja) 2005-11-22 2009-04-23 ネオガイド システムズ， インコーポレイテッド 曲げ可能な装置の形状を決定する方法
US8083879B2 (en) * 2005-11-23 2011-12-27 Intuitive Surgical Operations, Inc. Non-metallic, multi-strand control cable for steerable instruments
US7896805B2 (en) * 2005-11-23 2011-03-01 Given Imaging Ltd. In-vivo imaging device and optical system thereof
WO2007063550A2 (en) * 2005-12-02 2007-06-07 Given Imaging Ltd. System and device for in vivo procedures
US20070167834A1 (en) * 2005-12-29 2007-07-19 Amit Pascal In-vivo imaging optical device and method
US9320417B2 (en) 2005-12-29 2016-04-26 Given Imaging Ltd. In-vivo optical imaging device with backscatter blocking
US20070156051A1 (en) * 2005-12-29 2007-07-05 Amit Pascal Device and method for in-vivo illumination
JP5680826B2 (ja) 2006-01-10 2015-03-04 ザ ジェネラル ホスピタル コーポレイション １以上のスペクトルを符号化する内視鏡技術によるデータ生成システム
WO2007084945A1 (en) * 2006-01-19 2007-07-26 The General Hospital Corporation Systems and methods for performing rapid fluorescense lifetime, excitation and emission spectral measurements
EP2289397A3 (de) * 2006-01-19 2011-04-06 The General Hospital Corporation Verfahren und Systeme zur optischen Bildgebung von epithelialen Luminalorganen durch Strahlenabtastung dieser
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
US20070171430A1 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and methods for providing mirror tunnel micropscopy
JP2009524066A (ja) * 2006-01-20 2009-06-25 ザ ジェネラル ホスピタル コーポレイション 波面変調を使用してスペックル低減を提供する光学的干渉断層撮影法のシステム、構成、及びプロセス
WO2007084933A2 (en) * 2006-01-20 2007-07-26 The General Hospital Corporation Systems and processes for providing endogenous molecular imaging with mid-infared light
WO2007149601A2 (en) * 2006-02-01 2007-12-27 The General Hospital Corporation Apparatus for controlling at least one of at least two sections of at least one fiber
JP5524487B2 (ja) * 2006-02-01 2014-06-18 ザ ジェネラル ホスピタル コーポレイション コンフォーマルレーザ治療手順を用いてサンプルの少なくとも一部分に電磁放射を放射する方法及びシステム。
US7538859B2 (en) * 2006-02-01 2009-05-26 The General Hospital Corporation Methods and systems for monitoring and obtaining information of at least one portion of a sample using conformal laser therapy procedures, and providing electromagnetic radiation thereto
JP5519152B2 (ja) 2006-02-08 2014-06-11 ザ ジェネラル ホスピタル コーポレイション 光学顕微鏡法を用いて解剖学的サンプルに関わる情報を取得するための装置
EP2309221A1 (de) * 2006-02-24 2011-04-13 The General Hospital Corporation Verfahren und Systeme zur Durchführung von winkelaufgelöster optischer Kohärenztomografie im Fourier-Bereich
WO2007103721A2 (en) * 2006-03-01 2007-09-13 The General Hospital Corporation System and method for providing cell specific laser therapy of atherosclerotic plaques by targeting light absorbers in macrophages
WO2007109540A2 (en) * 2006-03-17 2007-09-27 The General Hospital Corporation Arrangement, method and computer-accessible medium for identifying characteristics of at least a portion of a blood vessel contained within a tissue using spectral domain low coherence interferometry
WO2007118129A1 (en) * 2006-04-05 2007-10-18 The General Hospital Corporation Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample
WO2007133961A2 (en) 2006-05-10 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing frequency domain imaging of a sample
WO2007133964A2 (en) * 2006-05-12 2007-11-22 The General Hospital Corporation Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images
US8568299B2 (en) * 2006-05-19 2013-10-29 Intuitive Surgical Operations, Inc. Methods and apparatus for displaying three-dimensional orientation of a steerable distal tip of an endoscope
AU2007275720A1 (en) * 2006-07-18 2008-01-24 Boston Medical Center Corporation Device with integrated multi-fiber optical probe and methods of use
JP5693846B2 (ja) * 2006-07-21 2015-04-01 オンコスコープ・インコーポレーテツド 特に内視鏡用途に使用される光ファイバプローブで使用するための保護プローブ先端
WO2008016927A2 (en) * 2006-08-01 2008-02-07 The General Hospital Corporation Systems and methods for receiving and/or analyzing information associated with electro-magnetic radiation
FR2904927B1 (fr) * 2006-08-17 2018-05-18 Mauna Kea Technologies Utilisation d'un systeme d'imagerie par fluorescence confocale fibre in vivo in situ, systeme et procede d'imagerie par fluorescence confocale fibres in vivo in situ
WO2008024948A2 (en) * 2006-08-25 2008-02-28 The General Hospital Corporation Apparatus and methods for enhancing optical coherence tomography imaging using volumetric filtering techniques
US20080287808A1 (en) * 2006-09-12 2008-11-20 The General Hospital Corporation Apparatus, probe and method for providing depth assessment in an anatomical structure
WO2008049118A2 (en) * 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
US7949019B2 (en) * 2007-01-19 2011-05-24 The General Hospital Wavelength tuning source based on a rotatable reflector
US20080206804A1 (en) * 2007-01-19 2008-08-28 The General Hospital Corporation Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis
JP5507258B2 (ja) 2007-01-19 2014-05-28 ザ ジェネラル ホスピタル コーポレイション 光周波数領域イメージングにおける測定深度を制御するための装置及び方法
US8396539B2 (en) * 2007-02-16 2013-03-12 Medtronic, Inc. Implantable medical device having optical fiber for sensing electrical activity
US20080221443A1 (en) * 2007-03-07 2008-09-11 Ritchie Paul G Integrated Imaging and Biopsy System with Ancillary Device Authentication
US20080234586A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation System and method for providing noninvasive diagnosis of compartment syndrome using exemplary laser speckle imaging procedure
US20080234567A1 (en) * 2007-03-19 2008-09-25 The General Hospital Corporation Apparatus and method for providing a noninvasive diagnosis of internal bleeding
JP2008229024A (ja) * 2007-03-20 2008-10-02 Olympus Corp 蛍光観察装置
EP2602651A3 (de) * 2007-03-23 2014-08-27 The General Hospital Corporation Verfahren, Anordnungen und Vorrichtung zur Verwendung eines wellenlängengewobbelten Lasers anhand von Winkelabtastungs- und Dispersionsverfahren
WO2008121844A1 (en) * 2007-03-30 2008-10-09 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
WO2008131082A1 (en) 2007-04-17 2008-10-30 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy techniques
US8115919B2 (en) * 2007-05-04 2012-02-14 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using optical microscopy
US9226731B2 (en) * 2007-05-21 2016-01-05 The Board Of Regents Of The University Of Texas System Optically guided needle biopsy system using multi-modal spectroscopy in combination with a transrectal ultrasound probe
US8591521B2 (en) 2007-06-08 2013-11-26 United States Endoscopy Group, Inc. Retrieval device
US20090003666A1 (en) * 2007-06-27 2009-01-01 Wu Dee H System and methods for image analysis and treatment
EP2173254A2 (de) * 2007-07-31 2010-04-14 The General Hospital Corporation System und verfahren zur bereitstellung von strahlerfassungsmustern für hochgeschwindigkeits-abbildungen optischer dopplerfrequenzdomänen
WO2009029843A1 (en) * 2007-08-31 2009-03-05 The General Hospital Corporation System and method for self-interference fluoresence microscopy, and computer-accessible medium associated therewith
AU2008298551A1 (en) * 2007-09-13 2009-03-19 Duke University Apparatuses, systems, and methods for low-coherence interferometry (LCI)
EP2197546A1 (de) * 2007-09-14 2010-06-23 Light Sciences Oncology, Inc. Systeme, vorrichtungen und verfahren für die photoaktiv gestützte resektion
US20090073439A1 (en) * 2007-09-15 2009-03-19 The General Hospital Corporation Apparatus, computer-accessible medium and method for measuring chemical and/or molecular compositions of coronary atherosclerotic plaques in anatomical structures
US9220398B2 (en) 2007-10-11 2015-12-29 Intuitive Surgical Operations, Inc. System for managing Bowden cables in articulating instruments
WO2009049296A2 (en) * 2007-10-12 2009-04-16 The General Hospital Corporation Systems and processes for optical imaging of luminal anatomic structures
WO2009059034A1 (en) * 2007-10-30 2009-05-07 The General Hospital Corporation System and method for cladding mode detection
JP5968590B2 (ja) * 2007-11-05 2016-08-10 ケーシーアイ ライセンシング インコーポレイテッド 創面切除のための組織の同定
WO2009060460A2 (en) * 2007-11-09 2009-05-14 Given Imaging Ltd. Apparatus and methods for capsule endoscopy of the esophagus
US20090124927A1 (en) * 2007-11-13 2009-05-14 Chest Innovations, Inc. Endoscopic system for lung biopsy and biopsy method of insufflating gas to collapse a lung
US8290569B2 (en) * 2007-11-23 2012-10-16 Hologic, Inc. Open architecture tabletop patient support and coil system
US20090177094A1 (en) * 2008-01-08 2009-07-09 Oncoscope, Inc. Systems and methods for tissue examination, diagnostic, treatment, and/or monitoring
US20090225324A1 (en) * 2008-01-17 2009-09-10 The General Hospital Corporation Apparatus for providing endoscopic high-speed optical coherence tomography
US8115934B2 (en) * 2008-01-18 2012-02-14 The Board Of Trustees Of The University Of Illinois Device and method for imaging the ear using optical coherence tomography
US8983580B2 (en) 2008-01-18 2015-03-17 The Board Of Trustees Of The University Of Illinois Low-coherence interferometry and optical coherence tomography for image-guided surgical treatment of solid tumors
US11123047B2 (en) 2008-01-28 2021-09-21 The General Hospital Corporation Hybrid systems and methods for multi-modal acquisition of intravascular imaging data and counteracting the effects of signal absorption in blood
US9332942B2 (en) * 2008-01-28 2016-05-10 The General Hospital Corporation Systems, processes and computer-accessible medium for providing hybrid flourescence and optical coherence tomography imaging
WO2009100368A1 (en) 2008-02-06 2009-08-13 Neoguide Systems Inc. A segmented instrument having braking capabilities
US8182418B2 (en) * 2008-02-25 2012-05-22 Intuitive Surgical Operations, Inc. Systems and methods for articulating an elongate body
WO2009137701A2 (en) * 2008-05-07 2009-11-12 The General Hospital Corporation System, method and computer-accessible medium for tracking vessel motion during three-dimensional coronary artery microscopy
US8694266B2 (en) 2008-06-05 2014-04-08 The Regents Of The University Of Michigan Multimodal spectroscopic systems and methods for classifying biological tissue
US8239139B2 (en) * 2008-06-05 2012-08-07 The Regents Of The University Of Michigan Multimodal spectroscopic systems and methods for classifying biological tissue
US8234078B2 (en) * 2008-06-05 2012-07-31 The Regents Of The University Of Michigan Multimodal spectroscopic systems and methods for classifying biological tissue
EP2288948A4 (de) * 2008-06-20 2011-12-28 Gen Hospital Corp Anordnung aus kondensierten glasfaserkopplern und verfahren zu ihrer verwendung
JP5667051B2 (ja) * 2008-07-14 2015-02-12 ザ ジェネラル ホスピタル コーポレイション カラー内視鏡検査のための装置
US8416405B2 (en) * 2008-08-08 2013-04-09 Chemimage Corporation Raman chemical imaging of implantable drug delivery devices
US20100081926A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081928A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological Facilitation systems and methods
US20100081915A1 (en) * 2008-09-29 2010-04-01 Searete Llc, Alimited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081916A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware. Histological facilitation systems and methods
US20100081927A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081924A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US20110190662A1 (en) * 2008-10-01 2011-08-04 Beacon Endoscopic Corporation Rapid exchange fna biopsy device with diagnostic and therapeutic capabilities
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US9186128B2 (en) * 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US7862219B2 (en) * 2008-10-22 2011-01-04 Advanced Photodynamic Technologies, Inc. Optical fiber light diffusing device
US8937724B2 (en) 2008-12-10 2015-01-20 The General Hospital Corporation Systems and methods for extending imaging depth range of optical coherence tomography through optical sub-sampling
EP2389093A4 (de) 2009-01-20 2013-07-31 Gen Hospital Corp Endoskopische biopsievorrichtung sowie entsprechendes system und verfahren
WO2010085775A2 (en) * 2009-01-26 2010-07-29 The General Hospital Corporation System, method and computer-accessible medium for providing wide-field superresolution microscopy
CN104134928A (zh) 2009-02-04 2014-11-05 通用医疗公司 利用高速光学波长调谐源的设备和方法
WO2010105197A2 (en) 2009-03-12 2010-09-16 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measuring at least one mechanical property of tissue using coherent speckle techniques(s)
WO2010148503A1 (en) * 2009-06-23 2010-12-29 Sentinelle Medical Inc. Variable angle guide holder for a biopsy guide plug
US8516691B2 (en) 2009-06-24 2013-08-27 Given Imaging Ltd. Method of assembly of an in vivo imaging device with a flexible circuit board
JP5819823B2 (ja) 2009-07-14 2015-11-24 ザ ジェネラル ホスピタル コーポレイション 血管の内部の流れおよび圧力を測定する装置および装置の作動方法
FR2948007B1 (fr) * 2009-07-20 2012-06-08 Chab Lama Al Sonde a aiguille fibree tranchante pour le diagnostic optique en profondeur de tumeurs.
EP2485641A4 (de) * 2009-10-06 2015-10-14 Gen Hospital Corp Vorrichtung und verfahren zur abbildung einzelner zellen mit eosinophilen
JP5711260B2 (ja) * 2009-12-08 2015-04-30 ザ ジェネラル ホスピタル コーポレイション 光コヒーレンストモグラフィにより声帯襞を分析、診断及び治療モニタリングする方法及び装置
TWI511702B (zh) * 2009-12-11 2015-12-11 Univ Ishou Methods for the measurement of endothelial cell dilatation
CA2787696A1 (en) 2010-01-22 2011-07-28 Adam Wax Multiple window processing schemes for spectroscopic optical coherence tomography (oct) and fourier domain low coherence interferometry
US9823127B2 (en) 2010-01-22 2017-11-21 Duke University Systems and methods for deep spectroscopic imaging of biological samples with use of an interferometer and spectrometer
US20110201965A1 (en) * 2010-02-18 2011-08-18 John Anthony Hibner MRI Compatible Biopsy Device
HUE051135T2 (hu) 2010-03-05 2021-03-01 Massachusetts Gen Hospital Rendszerek mikroszkópikus képek elõállítására legalább egy anatómiai szerkezetrõl adott felbontással
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
US8666673B2 (en) 2010-05-14 2014-03-04 Biomerieux, Inc Identification and/or characterization of a microbial agent using taxonomic hierarchical classification
US9795301B2 (en) 2010-05-25 2017-10-24 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
US9557154B2 (en) 2010-05-25 2017-01-31 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
DE102010017117A1 (de) 2010-05-27 2011-12-01 Anne Schardey Chirurgisches Instrument
EP2575591A4 (de) 2010-06-03 2017-09-13 The General Hospital Corporation Vorrichtung und verfahren für geräte zur abbildung von strukturen in oder an einem oder mehreren lumenorganen
CN102846304A (zh) * 2010-07-15 2013-01-02 广州宝胆医疗器械科技有限公司 诊疗一体化共聚焦阴道镜系统
WO2012056991A1 (ja) 2010-10-26 2012-05-03 コニカミノルタオプト株式会社 プローブ
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
US9913596B2 (en) 2010-11-25 2018-03-13 Invivo Corporation Systems and methods for MRI guided trans-orifice and transperineal intervention apparatus with adjustable biopsy needle insertion
US8721077B2 (en) 2011-04-29 2014-05-13 The General Hospital Corporation Systems, methods and computer-readable medium for determining depth-resolved physical and/or optical properties of scattering media by analyzing measured data over a range of depths
US9237852B2 (en) 2011-05-18 2016-01-19 Konica Minolta, Inc. Probe
WO2013013049A1 (en) 2011-07-19 2013-01-24 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
JP5834584B2 (ja) * 2011-07-25 2015-12-24 ソニー株式会社 情報処理装置、情報処理方法、プログラム及び蛍光スペクトルの強度補正方法
WO2013029047A1 (en) 2011-08-25 2013-02-28 The General Hospital Corporation Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures
ES2727868T3 (es) 2011-09-22 2019-10-21 Univ George Washington Sistemas para visualizar el tejido ablacionado
KR20140102643A (ko) 2011-09-22 2014-08-22 더 조지 워싱턴 유니버시티 절제된 조직을 시각화하기 위한 시스템 및 방법
JP2015502562A (ja) 2011-10-18 2015-01-22 ザ ジェネラル ホスピタル コーポレイション 再循環光学遅延を生成および／または提供するための装置および方法
US9629528B2 (en) 2012-03-30 2017-04-25 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
EP2835094A4 (de) * 2012-04-05 2016-03-09 Sbi Pharmaceuticals Co Ltd Vorrichtung zur bestimmung der metastase von krebs auf wächterlymphknoten
US20130310680A1 (en) 2012-05-21 2013-11-21 The Regents Of The University Of Colorado, A Body Corporate Three-dimensional optical imaging and therapy of prostate cancer
US11490797B2 (en) 2012-05-21 2022-11-08 The General Hospital Corporation Apparatus, device and method for capsule microscopy
US9814448B2 (en) 2012-05-21 2017-11-14 Precision Biopsy, Inc. Three-dimensional optical imaging and therapy of prostate cancer
US9415550B2 (en) 2012-08-22 2016-08-16 The General Hospital Corporation System, method, and computer-accessible medium for fabrication miniature endoscope using soft lithography
CN104519782A (zh) * 2012-08-23 2015-04-15 思佰益药业股份有限公司 具备准直器的光动力学诊断装置
WO2014036470A1 (en) 2012-08-31 2014-03-06 Sloan-Kettering Institute For Cancer Research Particles, methods and uses thereof
WO2014080366A1 (en) * 2012-11-26 2014-05-30 Koninklijke Philips N.V. Spiral biopsy device
US9677869B2 (en) 2012-12-05 2017-06-13 Perimeter Medical Imaging, Inc. System and method for generating a wide-field OCT image of a portion of a sample
WO2014100380A2 (en) 2012-12-19 2014-06-26 Sloan-Kettering Institute For Cancer Research Multimodal particles, methods and uses thereof
EP2948758B1 (de) 2013-01-28 2024-03-13 The General Hospital Corporation Vorrichtung zur bereitstellung von gemeinsam mit optischer frequenzdomänenbildgebung aufgezeichneter diffuser spektroskopie
US10893806B2 (en) 2013-01-29 2021-01-19 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
US11179028B2 (en) 2013-02-01 2021-11-23 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
WO2014130736A1 (en) 2013-02-20 2014-08-28 Sloan-Kettering Institute For Cancer Research Wide field raman imaging apparatus and associated methods
US9526579B2 (en) * 2013-03-12 2016-12-27 Boston Scientific Scimed, Inc. Combination diffused and focused fiber optic for diagnosis and treatment of diseased cells
CA2906956A1 (en) * 2013-03-15 2014-09-18 Olive Medical Corporation Calibration using distal cap
WO2014144709A2 (en) 2013-03-15 2014-09-18 The General Hospital Corporation Methods and systems for characterizing an object
WO2014150274A1 (en) 2013-03-15 2014-09-25 Hologic, Inc. System and method for reviewing and analyzing cytological specimens
JP5988907B2 (ja) * 2013-03-27 2016-09-07 オリンパス株式会社 内視鏡システム
US10130322B2 (en) 2013-03-29 2018-11-20 General Electric Company Mammography device and method of controlling position alignment thereof
EP2997354A4 (de) 2013-05-13 2017-01-18 The General Hospital Corporation Erkennung einer selbstinterferierenden fluoreszenzphase und amplitude
US9913628B2 (en) 2013-06-26 2018-03-13 General Electric Company System and method for attaching a biopsy collecting device to a spectroscopy system
US10531862B2 (en) 2013-06-26 2020-01-14 General Electric Company System and method for attaching a biopsy collecting device to a spectroscopy system
EP3021735A4 (de) 2013-07-19 2017-04-19 The General Hospital Corporation Bestimmung der augenbewegung mittels netzhautabbildung mit rückkopplung
WO2015009932A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Imaging apparatus and method which utilizes multidirectional field of view endoscopy
EP3025173B1 (de) 2013-07-26 2021-07-07 The General Hospital Corporation Vorrichtung mit optische dispersion nutzender laseranordnung zur anwendung in der fourier-raum optischen kohärenztomographie
US9872700B2 (en) 2013-09-03 2018-01-23 United States Endoscopy Group, Inc. Endoscopic snare device
US9572591B2 (en) 2013-09-03 2017-02-21 United States Endoscopy Group, Inc. Endoscopic snare device
US11096584B2 (en) 2013-11-14 2021-08-24 The George Washington University Systems and methods for determining lesion depth using fluorescence imaging
US20150141847A1 (en) 2013-11-20 2015-05-21 The George Washington University Systems and methods for hyperspectral analysis of cardiac tissue
WO2015105870A1 (en) 2014-01-08 2015-07-16 The General Hospital Corporation Method and apparatus for microscopic imaging
WO2015116986A2 (en) 2014-01-31 2015-08-06 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
US10912947B2 (en) 2014-03-04 2021-02-09 Memorial Sloan Kettering Cancer Center Systems and methods for treatment of disease via application of mechanical force by controlled rotation of nanoparticles inside cells
US10228556B2 (en) 2014-04-04 2019-03-12 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
CN104000530B (zh) * 2014-06-06 2016-08-24 慈溪市桥头京姬电子元件厂 一种临时洗手装置
ES2907287T3 (es) 2014-07-25 2022-04-22 Massachusetts Gen Hospital Aparato para imagenología y diagnóstico in vivo
EP3180038A4 (de) 2014-07-28 2018-04-04 Memorial Sloan-Kettering Cancer Center Metall(oide)-chalkogen-nanopartikel als universelle bindemittel für medizinische isotope
WO2016073492A1 (en) 2014-11-03 2016-05-12 Luxcath, Llc. Systems and methods for assessment of contact quality
US10722301B2 (en) 2014-11-03 2020-07-28 The George Washington University Systems and methods for lesion assessment
WO2016149701A1 (en) 2015-03-19 2016-09-22 The Regents Of The University Of Michigan System for analyzing tissue
EP3317035A1 (de) 2015-07-01 2018-05-09 Memorial Sloan Kettering Cancer Center Anisotrope partikel, verfahren und verwendungen dafür
WO2017007870A1 (en) * 2015-07-07 2017-01-12 Precision Biopsy, Inc. Motorized optical imaging of prostate cancer
US10779904B2 (en) 2015-07-19 2020-09-22 460Medical, Inc. Systems and methods for lesion formation and assessment
US10537225B2 (en) * 2016-11-28 2020-01-21 Olympus Corporation Marking method and resecting method
JP2020506369A (ja) * 2016-12-15 2020-02-27 ジェモロジカル インスティテュート オブ アメリカ インコーポレイテッド（ジーアイエー） 宝石用原石のスクリーニング装置および方法
WO2018129551A1 (en) 2017-01-09 2018-07-12 United States Endoscopy Group, Inc. Endoscopic snare device
US10806334B2 (en) * 2017-02-28 2020-10-20 Verily Life Sciences Llc System and method for multiclass classification of images using a programmable light source
EP3646012B1 (de) * 2017-06-30 2023-03-08 Agency for Science, Technology and Research Sers-aktive opto-fluidische photonische kristallfaser-sonde einschliesslich einer biopsie-nadel und verfahren zur verwendung der sonde
US11234600B2 (en) * 2017-07-13 2022-02-01 The Board Of Regents For Oklahoma State University System and method for tissue visualization
EP3655748B1 (de) 2017-07-18 2023-08-09 Perimeter Medical Imaging, Inc. Probenbehälter zur stabilisierung und ausrichtung exzidierter biologischer gewebeproben zur ex-vivo-analyse
EP3540494B1 (de) 2018-03-16 2022-11-23 Leica Instruments (Singapore) Pte. Ltd. Chirurgisches mikroskop und mikroskopisches verfahren mit erweiterter realität
EP3876813A4 (de) * 2018-11-05 2022-08-10 Medivators Inc. Endoskopische fluoreszenzprüfvorrichtung
WO2020096888A1 (en) 2018-11-05 2020-05-14 Medivators Inc. Endoscope cleaning and inspection system and method
WO2020112500A1 (en) * 2018-11-30 2020-06-04 Verily Life Sciences Llc Endoscopic systems including a multimode optical fiber and a machine learning classifier for interrogating a portion of a body
EP3730042A1 (de) * 2019-02-07 2020-10-28 Canon U.S.A., Inc. Vorrichtung, verfahren und systeme zur verminderung von thermischem rauschen und umgebungslichtrauschen in der fluoreszenzbildgebung
JP2022543289A (ja) * 2019-08-05 2022-10-11 ジャイラス エーシーエムアイ インク ディー／ビー／エー オリンパス サージカル テクノロジーズ アメリカ 光学フィードバック信号スプリッタを用いたターゲット識別
US20210038062A1 (en) * 2019-08-05 2021-02-11 Gyrus Acmi, Inc. D/B/A Olympus Surgical Technologies America Optical fiber assembly
GB2601789A (en) * 2020-12-10 2022-06-15 Creo Medical Ltd Raman spectroscopy probe, Raman spectroscopy apparatus including the Raman spectroscopy probe and elongate assembly
DE102021204906A1 (de) 2021-05-14 2022-11-17 Richard Wolf Gmbh Biopsiesystem
US12053263B2 (en) * 2021-05-21 2024-08-06 Dermasensor, Inc. Dynamic calibration of light intensity in a system for non-invasive detection of skin cancer using elastic scattering spectroscopy

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5933388B2 (ja) 1976-03-19 1984-08-15 高美 上原 単独操作可能な生検用フアイバ−スコ−プ
US4479499A (en) 1982-01-29 1984-10-30 Alfano Robert R Method and apparatus for detecting the presence of caries in teeth using visible light
DE3337016T1 (de) 1982-03-16 1984-12-13 Laserscope, Inc., Arlington Heights, Ill. Chirurgisches Gerät für innere Operationen
JPS5940830A (ja) 1982-08-31 1984-03-06 浜松ホトニクス株式会社 レ−ザ光パルスを用いた癌の診断装置
US5139025A (en) 1983-10-14 1992-08-18 Somanetics Corporation Method and apparatus for in vivo optical spectroscopic examination
JPS60209146A (ja) * 1984-03-31 1985-10-21 Olympus Optical Co Ltd 螢光スペクトル分析装置
US4651201A (en) * 1984-06-01 1987-03-17 Arnold Schoolman Stereoscopic endoscope arrangement
US5106387A (en) 1985-03-22 1992-04-21 Massachusetts Institute Of Technology Method for spectroscopic diagnosis of tissue
US4718417A (en) 1985-03-22 1988-01-12 Massachusetts Institute Of Technology Visible fluorescence spectral diagnostic for laser angiosurgery
US5318024A (en) 1985-03-22 1994-06-07 Massachusetts Institute Of Technology Laser endoscope for spectroscopic imaging
US5125404A (en) 1985-03-22 1992-06-30 Massachusetts Institute Of Technology Apparatus and method for obtaining spectrally resolved spatial images of tissue
US5104392A (en) 1985-03-22 1992-04-14 Massachusetts Institute Of Technology Laser spectro-optic imaging for diagnosis and treatment of diseased tissue
US5199431A (en) 1985-03-22 1993-04-06 Massachusetts Institute Of Technology Optical needle for spectroscopic diagnosis
CN85100424B (zh) 1985-04-01 1986-10-29 上海医疗器械研究所 恶性肿瘤固有荧光诊断仪
AT387860B (de) 1985-09-16 1989-03-28 Optical Sensing Technology Verfahren und vorrichtung zur tumordiagnose mittels sera
US5042494A (en) 1985-11-13 1991-08-27 Alfano Robert R Method and apparatus for detecting cancerous tissue using luminescence excitation spectra
US4895156A (en) 1986-07-02 1990-01-23 Schulze John E Sensor system using fluorometric decay measurements
US4981138A (en) 1988-06-30 1991-01-01 Yale University Endoscopic fiberoptic fluorescence spectrometer
US5402778A (en) 1993-01-19 1995-04-04 Nim Incorporated Spectrophotometric examination of tissue of small dimension
US5122974A (en) 1989-02-06 1992-06-16 Nim, Inc. Phase modulated spectrophotometry
US5596987A (en) 1988-11-02 1997-01-28 Noninvasive Technology, Inc. Optical coupler for in vivo examination of biological tissue
US4972331A (en) 1989-02-06 1990-11-20 Nim, Inc. Phase modulated spectrophotometry
US5386827A (en) 1993-03-30 1995-02-07 Nim Incorporated Quantitative and qualitative in vivo tissue examination using time resolved spectroscopy
US5555885A (en) 1988-12-21 1996-09-17 Non-Invasive Technology, Inc. Examination of breast tissue using time-resolved spectroscopy
EP0449883B1 (de) 1988-12-21 1996-01-31 Massachusetts Institute Of Technology Verfahren für laserinduzierte fluoreszenz von gewebe
US5553614A (en) 1988-12-21 1996-09-10 Non-Invasive Technology, Inc. Examination of biological tissue using frequency domain spectroscopy
US5187672A (en) 1989-02-06 1993-02-16 Nim Incorporated Phase modulation spectroscopic system
US5353799A (en) 1991-01-22 1994-10-11 Non Invasive Technology, Inc. Examination of subjects using photon migration with high directionality techniques
SE8900612D0 (sv) 1989-02-22 1989-02-22 Jonas Johansson Vaevnadskarakterisering utnyttjande ett blodfritt fluorescenskriterium
US5421337A (en) 1989-04-14 1995-06-06 Massachusetts Institute Of Technology Spectral diagnosis of diseased tissue
US5201318A (en) 1989-04-24 1993-04-13 Rava Richard P Contour mapping of spectral diagnostics
US5369496A (en) 1989-11-13 1994-11-29 Research Foundation Of City College Of New York Noninvasive method and apparatus for characterizing biological materials
JP2852774B2 (ja) 1989-11-22 1999-02-03 株式会社エス・エル・ティ・ジャパン 生体組織の診断装置およびこの診断装置を備えた治療装置
US5131398A (en) 1990-01-22 1992-07-21 Mediscience Technology Corp. Method and apparatus for distinguishing cancerous tissue from benign tumor tissue, benign tissue or normal tissue using native fluorescence
US5431645A (en) * 1990-05-10 1995-07-11 Symbiosis Corporation Remotely activated endoscopic tools such as endoscopic biopsy forceps
US5062428A (en) 1990-06-04 1991-11-05 Nim Incorporated Method and device for in vivo diagnosis detecting IR emission by body organ
DE69132273D1 (de) 1990-10-10 2000-08-03 Univ Maryland Verfahren und vorrichtung zur bestimmung von lebensdauer von fluoreszenz in der durchflusscytometrie
EP0568596A1 (de) 1991-01-24 1993-11-10 The University Of Maryland Verfahren und gerät zur mehrdimensionalen abbildung mit verwendung der phasenfluoreszenzlebzeit
US5168162A (en) 1991-02-04 1992-12-01 Cornell Research Foundation, Inc. Method of detecting the presence of anomalies in exfoliated cells using infrared spectroscopy
US5261410A (en) 1991-02-07 1993-11-16 Alfano Robert R Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy
US5303026A (en) 1991-02-26 1994-04-12 The Regents Of The University Of California Los Alamos National Laboratory Apparatus and method for spectroscopic analysis of scattering media
US5293872A (en) * 1991-04-03 1994-03-15 Alfano Robert R Method for distinguishing between calcified atherosclerotic tissue and fibrous atherosclerotic tissue or normal cardiovascular tissue using Raman spectroscopy
US5318023A (en) 1991-04-03 1994-06-07 Cedars-Sinai Medical Center Apparatus and method of use for a photosensitizer enhanced fluorescence based biopsy needle
US5377676A (en) 1991-04-03 1995-01-03 Cedars-Sinai Medical Center Method for determining the biodistribution of substances using fluorescence spectroscopy
JP3479069B2 (ja) 1991-04-29 2003-12-15 マサチューセッツ・インステチュート・オブ・テクノロジー 光学的イメージ形成および測定の方法および装置
US6134003A (en) * 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
US5465147A (en) 1991-04-29 1995-11-07 Massachusetts Institute Of Technology Method and apparatus for acquiring images using a ccd detector array and no transverse scanner
US5196709A (en) 1991-05-03 1993-03-23 University Of Maryland Systems Fluorometry method and apparatus using a semiconductor laser diode as a light source
CA2042075C (en) 1991-05-08 2001-01-23 Branko Palcic Endoscopic imaging system
US5203328A (en) 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
US5467767A (en) 1991-11-25 1995-11-21 Alfano; Robert R. Method for determining if tissue is malignant as opposed to non-malignant using time-resolved fluorescence spectroscopy
US5348018A (en) 1991-11-25 1994-09-20 Alfano Robert R Method for determining if tissue is malignant as opposed to non-malignant using time-resolved fluorescence spectroscopy
US5635402A (en) 1992-03-05 1997-06-03 Alfano; Robert R. Technique for determining whether a cell is malignant as opposed to non-malignant using extrinsic fluorescence spectroscopy
WO1994012095A2 (en) 1992-11-18 1994-06-09 Spectrascience, Inc. Apparatus for diagnostic imaging
US5383467A (en) 1992-11-18 1995-01-24 Spectrascience, Inc. Guidewire catheter and apparatus for diagnostic imaging
US5350375A (en) 1993-03-15 1994-09-27 Yale University Methods for laser induced fluorescence intensity feedback control during laser angioplasty
US5413108A (en) 1993-04-21 1995-05-09 The Research Foundation Of City College Of New York Method and apparatus for mapping a tissue sample for and distinguishing different regions thereof based on luminescence measurements of cancer-indicative native fluorophor
US5349964A (en) 1993-05-05 1994-09-27 Intelliwire, Inc. Device having an electrically actuatable section with a portion having a current shunt and method
US5421339A (en) 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence
US5673701A (en) 1994-10-07 1997-10-07 Non Invasive Technology, Inc. Optical techniques for examination of biological tissue
US5474910A (en) 1993-10-15 1995-12-12 Alfano; Robert R. Method and device for detecting biological molecules and/or microorganisms within a desired area or space
US5408966A (en) 1993-12-23 1995-04-25 Ford Motor Company System and method for synchronously activating cylinders within a variable displacement engine
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US5650135A (en) 1994-07-01 1997-07-22 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US5599717A (en) 1994-09-02 1997-02-04 Martin Marietta Energy Systems, Inc. Advanced synchronous luminescence system
US5579773A (en) 1994-09-30 1996-12-03 Martin Marietta Energy Systems, Inc. Laser-induced differential normalized fluorescence method for cancer diagnosis
JPH08224240A (ja) * 1995-02-22 1996-09-03 Olympus Optical Co Ltd 蛍光診断装置
US5612540A (en) 1995-03-31 1997-03-18 Board Of Regents, The University Of Texas Systems Optical method for the detection of cervical neoplasias using fluorescence spectroscopy
DE19533856A1 (de) * 1995-09-13 1997-03-20 Balazs Mattias Medizinisches Instrument
IT1277690B1 (it) * 1995-12-22 1997-11-11 Bieffe Medital Spa Sistema di sostegno ed attuazione a vertebre in particolare per strumenti chirurgici e diagnostici
US5647368A (en) 1996-02-28 1997-07-15 Xillix Technologies Corp. Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract
US5843000A (en) * 1996-05-07 1998-12-01 The General Hospital Corporation Optical biopsy forceps and method of diagnosing tissue
US5762613A (en) 1996-05-07 1998-06-09 Spectrascience, Inc. Optical biopsy forceps

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EP2018824B1 (de) 2010-07-21
JP4477230B2 (ja) 2010-06-09
EP1065970B1 (de) 2008-10-29
EP2018824A1 (de) 2009-01-28
ATE412363T1 (de) 2008-11-15
DE69942624D1 (de) 2010-09-02
CA2322768C (en) 2008-08-05
CA2322768A1 (en) 1999-09-16
EP1065970A1 (de) 2001-01-10
JP2010088929A (ja) 2010-04-22
US6174291B1 (en) 2001-01-16
JP2002505900A (ja) 2002-02-26
WO1999045838A1 (en) 1999-09-16

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