ATE388240T1 - Methode zur verwendung einer qualitätsmasszahl zur feststellung der qualität von biochemischen auftrennungen - Google Patents

Methode zur verwendung einer qualitätsmasszahl zur feststellung der qualität von biochemischen auftrennungen

Info

Publication number
ATE388240T1
ATE388240T1 AT99909649T AT99909649T ATE388240T1 AT E388240 T1 ATE388240 T1 AT E388240T1 AT 99909649 T AT99909649 T AT 99909649T AT 99909649 T AT99909649 T AT 99909649T AT E388240 T1 ATE388240 T1 AT E388240T1
Authority
AT
Austria
Prior art keywords
quality
quality metric
separation
run
data
Prior art date
Application number
AT99909649T
Other languages
German (de)
English (en)
Inventor
Elaine Mansfield
Lian-She Zhao
Marina Vainer
Curtis R Kautzer
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Application granted granted Critical
Publication of ATE388240T1 publication Critical patent/ATE388240T1/de

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8665Signal analysis for calibrating the measuring apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8624Detection of slopes or peaks; baseline correction
    • G01N30/8631Peaks
    • G01N30/8634Peak quality criteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/129Using chemometrical methods
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8624Detection of slopes or peaks; baseline correction
    • G01N30/8631Peaks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • G01N30/8658Optimising operation parameters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Quality & Reliability (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AT99909649T 1998-03-06 1999-02-25 Methode zur verwendung einer qualitätsmasszahl zur feststellung der qualität von biochemischen auftrennungen ATE388240T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/036,767 US6019896A (en) 1998-03-06 1998-03-06 Method for using a quality metric to assess the quality of biochemical separations

Publications (1)

Publication Number Publication Date
ATE388240T1 true ATE388240T1 (de) 2008-03-15

Family

ID=21890529

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99909649T ATE388240T1 (de) 1998-03-06 1999-02-25 Methode zur verwendung einer qualitätsmasszahl zur feststellung der qualität von biochemischen auftrennungen

Country Status (6)

Country Link
US (1) US6019896A (https=)
EP (1) EP1070142B1 (https=)
JP (1) JP4360479B2 (https=)
AT (1) ATE388240T1 (https=)
DE (1) DE69938296T2 (https=)
WO (1) WO1999045148A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US20030170734A1 (en) * 2000-04-28 2003-09-11 Stephen Williams Multiplexed assays using electrophoretically separated molecular tags
JP2004516455A (ja) * 2000-07-21 2004-06-03 アプレラ コーポレイション 生物学的データを評価するための方法、システム、および製品
US20020116135A1 (en) * 2000-07-21 2002-08-22 Pasika Hugh J. Methods, systems, and articles of manufacture for evaluating biological data
GB0119959D0 (en) * 2001-08-16 2001-10-10 Sec Dep Of The Home Department Improvements in and relating to analysis
SE0200949D0 (sv) * 2002-03-27 2002-03-27 Biacore Ab Method and system for curve quality control
WO2003085374A2 (en) * 2002-04-02 2003-10-16 Aclara Biosciences, Inc. Multiplexed assays using electrophoretically separated molecular tags
DE10315581B4 (de) * 2003-04-05 2007-06-28 Agilent Technologies, Inc. (n.d.Ges.d.Staates Delaware), Palo Alto Verfahren zur Qualitätsbestimmung von RNA-Proben
WO2006130165A2 (en) 2004-09-02 2006-12-07 Vialogy Corp. Detecting events of interest using quantum resonance interferometry
GB0419482D0 (en) * 2004-09-02 2004-10-06 Sec Dep For The Home Departmen Improvements in and relating to analysis
JP2006230917A (ja) * 2005-02-28 2006-09-07 Kaoru Imaoka 重心動揺計および重心動揺特性評価方法
US7799527B2 (en) * 2005-07-01 2010-09-21 Illumina, Inc. Systems and methods for automated quality control of polymer synthesis
US10488393B2 (en) 2010-09-30 2019-11-26 Robert Bosch Gmbh Device and method for self-referenced confidence test
US20140149050A1 (en) * 2011-07-08 2014-05-29 Shimadzu Corporation Data processing system for chromatograph
WO2013077864A1 (en) * 2011-11-22 2013-05-30 Robert Bosch Gmbh Method for self-referenced confidence test
EP3742159A1 (en) * 2019-05-24 2020-11-25 Sartorius Stedim Biotech GmbH Chromatography method, method of determining the influence of the interdependency of at least two parameters in a chromatography method and method of obtaining at least one chromatography method parameter
EP3742160B1 (en) 2019-05-24 2023-08-09 Sartorius Stedim Biotech GmbH Chromatography method, method of determining the concentration of at least one compound in a chromatography method and method of obtaining at least one chromatography method parameter
US12594557B2 (en) 2019-08-12 2026-04-07 Intabio, Llc Isoelectric focusing devices and fixtures
US11285484B2 (en) 2019-08-12 2022-03-29 Intabio, Llc Multichannel isoelectric focusing devices and high voltage power supplies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359320A3 (en) * 1988-09-14 1991-10-23 Philips Electronics Uk Limited Chromatography apparatus
US5558998A (en) * 1992-02-25 1996-09-24 The Regents Of The Univ. Of California DNA fragment sizing and sorting by laser-induced fluorescence
US5580728A (en) * 1994-06-17 1996-12-03 Perlin; Mark W. Method and system for genotyping
US5604097A (en) * 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US6015667A (en) * 1996-06-03 2000-01-18 The Perkin-Emer Corporation Multicomponent analysis method including the determination of a statistical confidence interval

Also Published As

Publication number Publication date
JP2002505442A (ja) 2002-02-19
EP1070142A1 (en) 2001-01-24
JP4360479B2 (ja) 2009-11-11
DE69938296T2 (de) 2009-03-19
DE69938296D1 (de) 2008-04-17
WO1999045148A1 (en) 1999-09-10
US6019896A (en) 2000-02-01
EP1070142B1 (en) 2008-03-05
EP1070142A4 (en) 2006-07-19

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