ATE286055T1 - Kondensierte pyrrolocarbazole - Google Patents
Kondensierte pyrrolocarbazoleInfo
- Publication number
- ATE286055T1 ATE286055T1 AT00204170T AT00204170T ATE286055T1 AT E286055 T1 ATE286055 T1 AT E286055T1 AT 00204170 T AT00204170 T AT 00204170T AT 00204170 T AT00204170 T AT 00204170T AT E286055 T1 ATE286055 T1 AT E286055T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibition
- disclosed
- compounds
- fused pyrrolocarbazoles
- pyrrolocarbazoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/323,755 US5475110A (en) | 1994-10-14 | 1994-10-14 | Fused Pyrrolocarbazoles |
US08/427,160 US5591855A (en) | 1994-10-14 | 1995-04-24 | Fused pyrrolocarbazoles |
US08/452,335 US5594009A (en) | 1994-10-14 | 1995-05-26 | Fused pyrrolocarbazoles |
US08/526,798 US5705511A (en) | 1994-10-14 | 1995-09-11 | Fused pyrrolocarbazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE286055T1 true ATE286055T1 (de) | 2005-01-15 |
Family
ID=27502273
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00204170T ATE286055T1 (de) | 1994-10-14 | 1995-10-03 | Kondensierte pyrrolocarbazole |
AT95938713T ATE211472T1 (de) | 1994-10-14 | 1995-10-03 | Kondensierte pyrrolocarbazole |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95938713T ATE211472T1 (de) | 1994-10-14 | 1995-10-03 | Kondensierte pyrrolocarbazole |
Country Status (17)
Country | Link |
---|---|
US (1) | US5705511A (de) |
EP (2) | EP1088823B1 (de) |
JP (1) | JP2001509775A (de) |
AT (2) | ATE286055T1 (de) |
AU (1) | AU705306B2 (de) |
BR (1) | BR9509348A (de) |
CA (1) | CA2202487C (de) |
DE (2) | DE69533899T2 (de) |
DK (2) | DK1088823T3 (de) |
ES (2) | ES2235769T3 (de) |
FI (1) | FI115911B (de) |
HK (1) | HK1036622A1 (de) |
MX (1) | MX9702682A (de) |
NO (1) | NO308996B1 (de) |
NZ (1) | NZ296244A (de) |
PT (2) | PT1088823E (de) |
WO (1) | WO1996011933A1 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5808060A (en) * | 1995-12-11 | 1998-09-15 | Cephalon, Inc. | Fused isoindolones |
SE9603283D0 (sv) * | 1996-09-10 | 1996-09-10 | Astra Ab | New compounds |
ATE208210T1 (de) * | 1997-08-15 | 2001-11-15 | Cephalon Inc | Kombination von proteintyrosin-kinaseinhibitoren und chemischer kastration zur behandlung von prostatakrebs |
CA2245029A1 (en) | 1998-03-13 | 1999-09-13 | University Of British Columbia | Granulatimide compounds as g2 checkpoint inhibitors |
AU758241B2 (en) * | 1998-03-13 | 2003-03-20 | University Of British Columbia, The | Granulatimide derivatives for use in cancer treatment |
US6811992B1 (en) * | 1998-05-14 | 2004-11-02 | Ya Fang Liu | Method for identifying MLK inhibitors for the treatment of neurological conditions |
US6127401A (en) * | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
US7795246B2 (en) * | 1998-08-06 | 2010-09-14 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
US6200968B1 (en) | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
DK1105728T3 (da) * | 1998-08-26 | 2005-08-08 | Cephalon Inc | Modulering af multiple lineage kinase-proteiner |
ATE361752T1 (de) * | 1998-09-25 | 2007-06-15 | Cephalon Inc | Methoden zur prophylaxe und behandlung von schäden der wahrnehmungshärchenzellen und der cochlearen neuronen |
US6841567B1 (en) * | 1999-02-12 | 2005-01-11 | Cephalon, Inc. | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
US6399780B1 (en) | 1999-08-20 | 2002-06-04 | Cephalon, Inc. | Isomeric fused pyrrolocarbazoles and isoindolones |
GB0002952D0 (en) * | 2000-02-09 | 2000-03-29 | Pharma Mar Sa | Process for producing kahalalide F compounds |
US7122679B2 (en) | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
US20060276497A1 (en) | 2000-05-09 | 2006-12-07 | Cephalon, Inc. | Novel multicyclic compounds and the use thereof |
EP1309721A2 (de) * | 2000-08-11 | 2003-05-14 | Cephalon, Inc. | Modulierung von mlk-(multiple lineage kinase) proteinen |
AU2001285205B2 (en) * | 2000-08-25 | 2007-03-01 | Cephalon, Inc. | Fused pyrrolocarbazoles against inflammation |
US6630500B2 (en) * | 2000-08-25 | 2003-10-07 | Cephalon, Inc. | Selected fused pyrrolocarbazoles |
US6653290B2 (en) * | 2000-10-06 | 2003-11-25 | Bristol-Myers Squibb Company | Tumor proliferation inhibitors |
US6610727B2 (en) | 2000-10-06 | 2003-08-26 | Bristol-Myers Squibb Company | Anhydro sugar derivatives of indolocarbazoles |
US6677450B2 (en) | 2000-10-06 | 2004-01-13 | Bristol-Myers Squibb Company | Topoisomerase inhibitors |
US6855698B2 (en) | 2001-03-22 | 2005-02-15 | Bristol-Myers Squibb Company | Topoisomerase I selective cytotoxic sugar derivatives of indolopyrrolocarbazoles |
AR035971A1 (es) * | 2001-05-16 | 2004-07-28 | Cephalon Inc | Metodos para el tratamiento y la prevencion del dolor |
FR2826653B1 (fr) * | 2001-06-29 | 2005-10-14 | Servier Lab | Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
IL144583A0 (en) | 2001-07-26 | 2002-05-23 | Peptor Ltd | Chimeric protein kinase inhibitors |
US20050054555A1 (en) * | 2001-10-19 | 2005-03-10 | Jose Jimeno | Kahalalide compounds for use in cancer therapy |
WO2003104482A1 (en) * | 2002-06-05 | 2003-12-18 | Metabolic Engineering Laboratories Co., Ltd. | Signals and molecular species involved in senescence |
FR2845997B1 (fr) * | 2002-10-18 | 2004-12-24 | Servier Lab | Nouveaux derives de[1,4]benzodioxino[2,3-e]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
GB0304367D0 (en) * | 2003-02-26 | 2003-04-02 | Pharma Mar Sau | Methods for treating psoriasis |
US7507708B2 (en) * | 2003-02-26 | 2009-03-24 | Pharma Mar, S.A.U. | Antitumoral compounds |
EP1653972A1 (de) * | 2003-07-23 | 2006-05-10 | Creabilis Therapeutics s.r.l. | Topische anwendung von tyrosinkinase-hemmern mikrobiellen ursprungs zur prävention und behandlung von hauterkrankungen, die durch übermässige zellproliferation gekennzeichnet sind |
GB0321066D0 (en) * | 2003-09-09 | 2003-10-08 | Pharma Mar Sau | New antitumoral compounds |
US7169802B2 (en) * | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US7241779B2 (en) | 2003-12-23 | 2007-07-10 | Cephalon, Inc. | Fused pyrrolocarbazoles |
MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
US20060058250A1 (en) * | 2004-09-10 | 2006-03-16 | Cephalon, Inc. | Methods of treating proliferative skin diseases using carbazole derivatives |
KR100734429B1 (ko) * | 2004-12-06 | 2007-07-03 | 재단법인서울대학교산학협력재단 | 노화에 관여하는 신호 및 분자종 |
US20060134174A1 (en) * | 2004-12-22 | 2006-06-22 | Bausch & Lomb Incorporated | Pharmaceutical delivery system and method of use |
US20060134176A1 (en) * | 2004-12-22 | 2006-06-22 | Bausch & Lomb Incorporated | Pharmaceutical delivery system and method of use |
US20060134175A1 (en) * | 2004-12-22 | 2006-06-22 | Stephen Bartels | Drug eluting pharmaceutical delivery system for treatment of ocular disease and method of use |
WO2007002670A2 (en) * | 2005-06-28 | 2007-01-04 | Bausch & Lomb Incorporated | Method of lowering intraocular pressure |
AU2006301518B2 (en) | 2005-10-11 | 2012-05-17 | Merck Patent Gmbh | EGFR dependent modulation of chemokine expression and influence on therapy and diagnosis of tumors and side effects thereof |
US20070249590A1 (en) * | 2005-10-28 | 2007-10-25 | Wilson Lawrence J | Substituted indolo[2,3-a]pyrrolo[3,4-c]carbazole compounds useful in treating kinase disorders |
US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
KR100831367B1 (ko) | 2007-02-16 | 2008-05-22 | 재단법인서울대학교산학협력재단 | 아데닐일 시클라아제의 억제제를 노화 세포에 처리하는 단계를 포함하는 세포의 노화 조절방법 및 아데닐일 시클라아제의 억제제를 포함하는 세포 노화 조절용 조성물 |
JP2011500723A (ja) * | 2007-10-19 | 2011-01-06 | ファルマ・マール・ソシエダード・アノニマ | 改善された抗腫瘍治療 |
WO2009067221A2 (en) * | 2007-11-20 | 2009-05-28 | Cephalon, Inc. | Microemulsion containing indolocarbazole compound and dosage forms containing the same |
JP5583592B2 (ja) * | 2007-11-30 | 2014-09-03 | ニューリンク ジェネティクス コーポレイション | Ido阻害剤 |
AR074374A1 (es) * | 2008-11-19 | 2011-01-12 | Cephalon Inc | Formas de un compuesto de pirrolocarbazol fusionado, composiciones que las comprenden y su uso en el tratamiento de la angiogénesis y los tumores sólidos. |
EP2192121A1 (de) * | 2008-11-27 | 2010-06-02 | Cephalon France | Regioselektive Reduktion von fusionierten Pyrrolocarbazol-5,7-Dionen |
JP5390693B2 (ja) * | 2009-03-30 | 2014-01-15 | ドゥクサン ハイ メタル カンパニー リミテッド | 有機電子素子及びその化合物、端末 |
KR101182438B1 (ko) * | 2009-08-14 | 2012-09-12 | 삼성디스플레이 주식회사 | 유기 발광 소자 |
CN104968680A (zh) | 2012-12-21 | 2015-10-07 | 索兰徳特医院 | 神经障碍和疼痛的egfr靶向疗法 |
EP3570832A4 (de) | 2017-01-17 | 2020-06-10 | Board Of Regents, The University Of Texas System | Verbindungen als inhibitoren der indolamin-2,3-dioxygenase und/oder tryptophan-dioxygenase |
DE102017117328A1 (de) * | 2017-07-31 | 2019-01-31 | Mitsubishi Polyester Film Gmbh | Peelfähige Polyesterfolie, Verfahren zu ihrer Herstellung und ihre Verwendung |
EP3823604A4 (de) | 2018-07-17 | 2022-03-16 | Board of Regents, The University of Texas System | Verbindungen als inhibitoren der indolamin-2,3-dioxygenase und/oder tryptophan-dioxygenase |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4552842A (en) * | 1983-01-28 | 1985-11-12 | Bristol-Myers Company | Process for producing rebeccamycin |
US4923986A (en) * | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
DE3835842A1 (de) * | 1988-10-21 | 1990-04-26 | Goedecke Ag | Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
IL89167A (en) * | 1988-02-10 | 1994-02-27 | Hoffmann La Roche | Substituted pyrroles, their manufacture and pharmaceutical compositions containing them |
DE3833008A1 (de) * | 1988-09-29 | 1990-04-05 | Goedecke Ag | Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
MC2096A1 (fr) * | 1989-02-23 | 1991-02-15 | Hoffmann La Roche | Pyrroles substitues |
US5185260A (en) * | 1991-08-29 | 1993-02-09 | The United States Of America As Represented By The United States Department Of Energy | Method for distinguishing normal and transformed cells using G1 kinase inhibitors |
NZ245203A (en) * | 1991-11-29 | 1997-07-27 | Banyu Pharma Co Ltd | 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates |
US6271242B1 (en) * | 1992-02-10 | 2001-08-07 | Bristol-Myers Squibb Co. | Method for treating cancer using a tyrosine protein kinase inhibitor |
US5405864A (en) * | 1993-10-15 | 1995-04-11 | Syntex (U.S.A.) Inc. | Chemotherapeutic maleimides |
DE4337521A1 (de) * | 1993-11-03 | 1995-05-04 | Teves Gmbh Alfred | Verfahren zur Funktionsprüfung eines hydraulischen Aggregats |
-
1995
- 1995-09-11 US US08/526,798 patent/US5705511A/en not_active Expired - Lifetime
- 1995-10-03 PT PT00204170T patent/PT1088823E/pt unknown
- 1995-10-03 BR BR9509348A patent/BR9509348A/pt not_active IP Right Cessation
- 1995-10-03 CA CA002202487A patent/CA2202487C/en not_active Expired - Lifetime
- 1995-10-03 AU AU39986/95A patent/AU705306B2/en not_active Expired
- 1995-10-03 ES ES00204170T patent/ES2235769T3/es not_active Expired - Lifetime
- 1995-10-03 ES ES95938713T patent/ES2170812T3/es not_active Expired - Lifetime
- 1995-10-03 MX MX9702682A patent/MX9702682A/es unknown
- 1995-10-03 DE DE69533899T patent/DE69533899T2/de not_active Expired - Lifetime
- 1995-10-03 AT AT00204170T patent/ATE286055T1/de active
- 1995-10-03 DK DK00204170T patent/DK1088823T3/da active
- 1995-10-03 DK DK95938713T patent/DK0785938T3/da active
- 1995-10-03 AT AT95938713T patent/ATE211472T1/de active
- 1995-10-03 EP EP00204170A patent/EP1088823B1/de not_active Expired - Lifetime
- 1995-10-03 JP JP51328996A patent/JP2001509775A/ja not_active Ceased
- 1995-10-03 EP EP95938713A patent/EP0785938B1/de not_active Expired - Lifetime
- 1995-10-03 PT PT95938713T patent/PT785938E/pt unknown
- 1995-10-03 DE DE69524882T patent/DE69524882T2/de not_active Expired - Lifetime
- 1995-10-03 NZ NZ296244A patent/NZ296244A/en not_active IP Right Cessation
- 1995-10-03 WO PCT/US1995/012761 patent/WO1996011933A1/en active IP Right Grant
-
1997
- 1997-04-09 FI FI971479A patent/FI115911B/fi not_active IP Right Cessation
- 1997-04-11 NO NO971677A patent/NO308996B1/no not_active IP Right Cessation
-
2001
- 2001-10-04 HK HK01106989A patent/HK1036622A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69533899T2 (de) | 2005-12-08 |
EP1088823A1 (de) | 2001-04-04 |
EP0785938A1 (de) | 1997-07-30 |
ES2235769T3 (es) | 2005-07-16 |
CA2202487A1 (en) | 1996-04-25 |
MX9702682A (es) | 1998-02-28 |
EP1088823B1 (de) | 2004-12-29 |
EP0785938B1 (de) | 2002-01-02 |
NO308996B1 (no) | 2000-11-27 |
DE69524882T2 (de) | 2002-09-12 |
FI971479A0 (fi) | 1997-04-09 |
DK1088823T3 (da) | 2005-04-25 |
DE69524882D1 (de) | 2002-02-07 |
DK0785938T3 (da) | 2002-04-22 |
WO1996011933A1 (en) | 1996-04-25 |
US5705511A (en) | 1998-01-06 |
ES2170812T3 (es) | 2002-08-16 |
PT1088823E (pt) | 2005-03-31 |
ATE211472T1 (de) | 2002-01-15 |
NO971677D0 (no) | 1997-04-11 |
DE69533899D1 (de) | 2005-02-03 |
FI115911B (fi) | 2005-08-15 |
PT785938E (pt) | 2002-06-28 |
NO971677L (no) | 1997-06-11 |
HK1036622A1 (en) | 2002-01-11 |
AU3998695A (en) | 1996-05-06 |
NZ296244A (en) | 1998-11-25 |
JP2001509775A (ja) | 2001-07-24 |
BR9509348A (pt) | 1997-11-04 |
FI971479A (fi) | 1997-06-11 |
CA2202487C (en) | 2008-06-17 |
AU705306B2 (en) | 1999-05-20 |
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