ATE238789T1 - Verwendung von hydantoin-derivaten zur herstellung eines medikaments zur behandlung von refraktärer vasculitis. - Google Patents
Verwendung von hydantoin-derivaten zur herstellung eines medikaments zur behandlung von refraktärer vasculitis.Info
- Publication number
- ATE238789T1 ATE238789T1 AT99122051T AT99122051T ATE238789T1 AT E238789 T1 ATE238789 T1 AT E238789T1 AT 99122051 T AT99122051 T AT 99122051T AT 99122051 T AT99122051 T AT 99122051T AT E238789 T1 ATE238789 T1 AT E238789T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- vasculitis
- mrl
- therapeutic agent
- represent hydrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32479098 | 1998-11-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE238789T1 true ATE238789T1 (de) | 2003-05-15 |
Family
ID=18169718
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99122051T ATE238789T1 (de) | 1998-11-16 | 1999-11-16 | Verwendung von hydantoin-derivaten zur herstellung eines medikaments zur behandlung von refraktärer vasculitis. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6251929B1 (de) |
EP (1) | EP1018339B1 (de) |
JP (1) | JP4451521B2 (de) |
KR (1) | KR100648062B1 (de) |
CN (1) | CN1143674C (de) |
AT (1) | ATE238789T1 (de) |
AU (1) | AU754989B2 (de) |
CA (1) | CA2289880C (de) |
DE (1) | DE69907387T2 (de) |
ES (1) | ES2194412T3 (de) |
TW (1) | TW528595B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4711523B2 (ja) * | 2001-02-13 | 2011-06-29 | 日本臓器製薬株式会社 | 低アルブミン血症改善剤 |
TWI353979B (en) * | 2002-04-10 | 2011-12-11 | Nippon Zoki Pharmaceutical Co | Novel crystal form of 5-hydroxy-1-methylhydantoin |
US20060241162A1 (en) * | 2005-04-20 | 2006-10-26 | Kaoru Okamoto | Optically active (R)-hydantoin derivative |
US20060241163A1 (en) * | 2005-04-20 | 2006-10-26 | Kaoru Okamoto | Optically active (S)-hydantoin derivative |
TWI483729B (zh) | 2010-03-11 | 2015-05-11 | Nippon Zoki Pharmaceutical Co | 慢性前列腺炎、間質性膀胱炎及/或排尿障礙之改善或治療劑 |
CN103476923B (zh) | 2010-10-14 | 2015-04-29 | 日本脏器制药株式会社 | 软骨细胞中的胶原蛋白和蛋白聚糖合成的促进方法 |
TW201632516A (zh) | 2014-12-11 | 2016-09-16 | 哈佛大學校長及研究員協會 | 細胞壞死抑制劑與相關方法 |
TWI757511B (zh) | 2017-06-13 | 2022-03-11 | 國立研究開發法人國立癌症研究中心 | 乙內醯脲衍生物之用途 |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
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US4099007A (en) | 1969-04-02 | 1978-07-04 | Hoechst Aktiengesellschaft | N,n-substituted 2,4,5-triketoimidazolidines and a process for their preparation |
US3818031A (en) | 1971-03-26 | 1974-06-18 | Ciba Geigy Corp | Imidazolidinetrionecarboxylic acid derivatives |
CH563711A5 (en) | 1972-03-03 | 1975-07-15 | Ciba Geigy Ag | Agents for regulating plant metabolism - contg. imidazolidine-2,4,5-trione-3-carboxylic acid derivs. |
IL39042A (en) | 1971-03-26 | 1976-04-30 | Ciba Geigy Ag | 2,4,5-trioxoimidazolidine-1-carboxylic acid derivatives,their preparation and their use for the control of plant metabolism |
DE2612926A1 (de) | 1976-03-26 | 1977-10-06 | Boehringer Mannheim Gmbh | Neue acyl-derivate der 6-(alpha- amino-phenylacetamido)-penicillansaeure |
JPS554305A (en) | 1978-06-13 | 1980-01-12 | Nippon Zoki Pharmaceut Co Ltd | Remedy for disease caused by stress and its preparation |
JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
JPH0686436B2 (ja) | 1984-11-15 | 1994-11-02 | 日本臓器製薬株式会社 | 新規ヒダントイン誘導体及び該化合物を含有する医薬組成物 |
AU578068B2 (en) | 1984-03-08 | 1988-10-13 | Nippon Zoki Pharmaceutical Co., Ltd. | Hydantoin derivatives and pharmaceutical compositions containing them |
BE899531A (fr) | 1984-04-27 | 1984-08-16 | Wallone Region | Derives sulfures de l'hydantoine et compositions pharmaceutiques les contenant. |
US5078680A (en) | 1984-08-08 | 1992-01-07 | Survival Technology, Inc. | Automatic injector for emergency treatment |
US4832682A (en) | 1984-08-08 | 1989-05-23 | Survival Technology, Inc. | Injection method and apparatus with electrical blood absorbing stimulation |
US4658830A (en) | 1984-08-08 | 1987-04-21 | Survival Technology, Inc. | Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms |
US4661469A (en) | 1984-08-08 | 1987-04-28 | Survival Technology, Inc. | t-PA composition capable of being absorbed into the blood stream and method of administration |
ATE82505T1 (de) | 1984-08-08 | 1992-12-15 | Survival Technology | Absorptionsverbesserer. |
US4656034A (en) | 1985-05-20 | 1987-04-07 | Survival Technology, Inc. | Absorption enhancing agents |
US5340829A (en) | 1984-11-20 | 1994-08-23 | Washington Research Foundation | Immunoregulatory agents |
JPH0764729B2 (ja) | 1985-02-06 | 1995-07-12 | 日本臓器製薬株式会社 | イミダゾリジントリオン誘導体を含有する医薬組成物 |
DE3668888D1 (de) | 1985-02-06 | 1990-03-15 | Nippon Zoki Pharmaceutical Co | Ein imidazolidintrion-derivat oder ein seiner pharmazeutisch akzeptierbaren salze enthaltende pharmazeutische zusammenstellung. |
JP2567593B2 (ja) | 1986-12-29 | 1996-12-25 | 日本臓器製薬株式会社 | イミダゾリジントリオン誘導体及び該化合物を有効成分として含有するアレルギ−性疾患治療剤 |
JPS6456614A (en) | 1987-08-27 | 1989-03-03 | Ono Pharmaceutical Co | Maillard reaction inhibitor |
JP2673381B2 (ja) * | 1990-02-23 | 1997-11-05 | 持田製薬 株式会社 | 糖尿病前症治療剤および/または脂質低下剤 |
JPH01156965A (ja) | 1987-09-29 | 1989-06-20 | Taiho Yakuhin Kogyo Kk | チオヒダントイン化合物 |
JPH0219363A (ja) | 1988-07-06 | 1990-01-23 | Fujisawa Pharmaceut Co Ltd | イミダゾリジン誘導体 |
JP2544183B2 (ja) | 1988-07-29 | 1996-10-16 | 日本臓器製薬株式会社 | 新規パラバン酸誘導体及び該化合物を有効成分として含有する医薬組成物 |
JP2817219B2 (ja) | 1988-09-08 | 1998-10-30 | 武田薬品工業株式会社 | カルバジン酸誘導体、その製造法及び製剤 |
JPH02225485A (ja) | 1989-02-27 | 1990-09-07 | Taiho Yakuhin Kogyo Kk | チエノピリミジン―3―酢酸誘導体 |
CA2011899A1 (en) | 1989-03-13 | 1990-09-13 | Masaaki Toda | Benzopyran derivatives |
JP2678499B2 (ja) | 1989-08-09 | 1997-11-17 | 日本臓器製薬 株式会社 | 尿毒症毒素低下剤 |
JPH0667827A (ja) | 1992-08-18 | 1994-03-11 | Nec Software Ltd | データ表示制御装置 |
JP3267698B2 (ja) | 1992-10-27 | 2002-03-18 | 株式会社三和化学研究所 | ヒダントイン誘導体及びその塩並びにこれらを有効成分とするメイラード反応阻害剤 |
CA2134347C (en) | 1993-02-26 | 2003-04-29 | Koichi Yasumura | Thiazole or imidazole derivatives as maillard reaction inhibitors |
JPH06305964A (ja) | 1993-02-26 | 1994-11-01 | Otsuka Pharmaceut Co Ltd | メイラード反応阻害剤 |
ATE198743T1 (de) | 1994-07-29 | 2001-02-15 | Suntory Ltd | Imidazolidin-derivate und ihre verwendung |
JPH08157473A (ja) | 1994-10-06 | 1996-06-18 | Nissan Chem Ind Ltd | ピラゾール系チアゾリジン類 |
US5681843A (en) | 1994-12-20 | 1997-10-28 | Nippon Zoki Pharmaceutical Co., Ltd. | Parabanic acid derivatives |
US5912261A (en) | 1994-12-20 | 1999-06-15 | Nippon Zoki Pharmaceutical Co., Ltd. | Carboxyalkyl heterocyclic derivatives |
US6197806B1 (en) * | 1995-12-20 | 2001-03-06 | Nippon Zoki Pharmaceutical Co., Ltd. | Eliminating agent for activated oxygen and free radicals |
JPH10182460A (ja) | 1996-12-27 | 1998-07-07 | Nippon Zoki Pharmaceut Co Ltd | 3−デオキシグルコソン生成阻害剤 |
-
1999
- 1999-11-04 AU AU58283/99A patent/AU754989B2/en not_active Ceased
- 1999-11-05 US US09/434,494 patent/US6251929B1/en not_active Expired - Fee Related
- 1999-11-05 TW TW088119309A patent/TW528595B/zh not_active IP Right Cessation
- 1999-11-12 KR KR1019990050162A patent/KR100648062B1/ko not_active IP Right Cessation
- 1999-11-15 JP JP32353499A patent/JP4451521B2/ja not_active Expired - Lifetime
- 1999-11-15 CA CA002289880A patent/CA2289880C/en not_active Expired - Fee Related
- 1999-11-16 AT AT99122051T patent/ATE238789T1/de not_active IP Right Cessation
- 1999-11-16 CN CNB991235797A patent/CN1143674C/zh not_active Expired - Fee Related
- 1999-11-16 ES ES99122051T patent/ES2194412T3/es not_active Expired - Lifetime
- 1999-11-16 EP EP99122051A patent/EP1018339B1/de not_active Expired - Lifetime
- 1999-11-16 DE DE69907387T patent/DE69907387T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6251929B1 (en) | 2001-06-26 |
EP1018339B1 (de) | 2003-05-02 |
TW528595B (en) | 2003-04-21 |
CN1143674C (zh) | 2004-03-31 |
CA2289880A1 (en) | 2000-05-16 |
ES2194412T3 (es) | 2003-11-16 |
DE69907387D1 (de) | 2003-06-05 |
EP1018339A1 (de) | 2000-07-12 |
AU754989B2 (en) | 2002-11-28 |
KR20000035443A (ko) | 2000-06-26 |
JP2000212083A (ja) | 2000-08-02 |
JP4451521B2 (ja) | 2010-04-14 |
AU5828399A (en) | 2000-05-18 |
CA2289880C (en) | 2009-01-20 |
DE69907387T2 (de) | 2004-02-12 |
KR100648062B1 (ko) | 2006-11-23 |
CN1253775A (zh) | 2000-05-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1018339 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |