ATE217345T1 - Gereinigte hepatitis-c-virus hüllproteine zur diagnostischen und therapeutischen verwendung - Google Patents
Gereinigte hepatitis-c-virus hüllproteine zur diagnostischen und therapeutischen verwendungInfo
- Publication number
- ATE217345T1 ATE217345T1 AT95930434T AT95930434T ATE217345T1 AT E217345 T1 ATE217345 T1 AT E217345T1 AT 95930434 T AT95930434 T AT 95930434T AT 95930434 T AT95930434 T AT 95930434T AT E217345 T1 ATE217345 T1 AT E217345T1
- Authority
- AT
- Austria
- Prior art keywords
- diagnostic
- proteins
- virus
- enclosure
- therapeutic use
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 241000711549 Hepacivirus C Species 0.000 title 1
- 238000010504 bond cleavage reaction Methods 0.000 abstract 2
- 101710091045 Envelope protein Proteins 0.000 abstract 1
- 101710188315 Protein X Proteins 0.000 abstract 1
- 102100021696 Syncytin-1 Human genes 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
- C07K16/109—Hepatitis C virus; Hepatitis G virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24241—Use of virus, viral particle or viral elements as a vector
- C12N2770/24243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/915—Aspergillus flavus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94870132 | 1994-07-29 | ||
PCT/EP1995/003031 WO1996004385A2 (en) | 1994-07-29 | 1995-07-31 | Purified hepatitis c virus envelope proteins for diagnostic and therapeutic use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE217345T1 true ATE217345T1 (de) | 2002-05-15 |
Family
ID=8218662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95930434T ATE217345T1 (de) | 1994-07-29 | 1995-07-31 | Gereinigte hepatitis-c-virus hüllproteine zur diagnostischen und therapeutischen verwendung |
Country Status (13)
Country | Link |
---|---|
US (7) | US6150134A (de) |
EP (3) | EP1211315A1 (de) |
JP (3) | JPH09503396A (de) |
AT (1) | ATE217345T1 (de) |
BR (1) | BR9506059A (de) |
CA (1) | CA2172273A1 (de) |
DE (2) | DE69526636T3 (de) |
DK (1) | DK0721505T4 (de) |
ES (1) | ES2174957T5 (de) |
HK (1) | HK1049022A1 (de) |
PT (1) | PT721505E (de) |
SG (1) | SG71728A1 (de) |
WO (1) | WO1996004385A2 (de) |
Families Citing this family (58)
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---|---|---|---|---|
ES2174957T5 (es) | 1994-07-29 | 2006-12-16 | Innogenetics N.V. | Proteinas purificadas de envoltura de virus de la hepatitis c para uso diagnostico y terapeutico. |
US20040185061A1 (en) * | 1994-07-29 | 2004-09-23 | Innogenetics N.V. | Redox reversible HCV proteins with native-like conformation |
CA2195312A1 (en) | 1994-07-29 | 1996-02-15 | Mark Selby | Novel hepatitis c e1 and e2 truncated polypeptides and methods of obtaining the same |
AU7471698A (en) | 1997-05-06 | 1998-11-27 | Chiron Corporation | Intracellular production of hepatitis c e1 and e2 truncated polypeptides |
US20080076706A1 (en) | 1997-07-14 | 2008-03-27 | Bolder Biotechnology, Inc. | Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof |
US7153943B2 (en) | 1997-07-14 | 2006-12-26 | Bolder Biotechnology, Inc. | Derivatives of growth hormone and related proteins, and methods of use thereof |
US6753165B1 (en) | 1999-01-14 | 2004-06-22 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
ES2297889T3 (es) | 1997-07-14 | 2008-05-01 | Bolder Biotechnology, Inc. | Derivados de hormona de crecimiento y proteinas relacionadas. |
US7495087B2 (en) | 1997-07-14 | 2009-02-24 | Bolder Biotechnology, Inc. | Cysteine muteins in the C-D loop of human interleukin-11 |
WO2000042175A1 (en) * | 1999-01-14 | 2000-07-20 | Bolder Biotechnology Inc. | Methods for making proteins containing free cysteine residues |
ATE482974T1 (de) | 1997-11-06 | 2010-10-15 | Innogenetics Nv | Multimere peptide, die auf dem hepatitis c virus hüllprotein basieren, für diagnostische verwendung und für impfzwecke |
WO1999024054A1 (en) * | 1997-11-06 | 1999-05-20 | Innogenetics N.V. | Host derived proteins binding hcv: medical, diagnostic and purification use |
EP0947525A1 (de) | 1998-03-27 | 1999-10-06 | Innogenetics N.V. | Epitope in der viralen Hüllproteine und spezifische Antikörper gegen diese Epitope: Verwendung für die detektion von viralantigene im empfängergewebe |
ES2230851T5 (es) * | 1998-04-17 | 2009-06-25 | N.V. Innogenetics S.A. | Ensayos de inmunodiagnostico mejorados que usan agentes reductores. |
NZ528952A (en) * | 1998-06-24 | 2004-09-24 | Innogenetics N | Particles of HCV envelope proteins: use for vaccination |
US7108855B2 (en) * | 1998-06-24 | 2006-09-19 | Innogenetics N.V. | Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use |
AU5285899A (en) | 1998-07-21 | 2000-02-14 | Connex Gesellschaft Zur Optimierung Von Forschung Und Entwicklung Mbh | Anti hepatitis c virus antibody and uses thereof |
US20030180284A1 (en) * | 1998-11-05 | 2003-09-25 | Board Of Trustees Of Leland Stanford Junior University | Prevention and treatment of HCV infection employing antibodies directed against conformational and linear epitopes |
US8288126B2 (en) | 1999-01-14 | 2012-10-16 | Bolder Biotechnology, Inc. | Methods for making proteins containing free cysteine residues |
US7009044B1 (en) * | 1999-06-04 | 2006-03-07 | The United States Of America As Represented By The Department Of Health And Human Services | HCV/BVDV chimeric genomes and uses thereof |
CA2387666A1 (en) * | 1999-10-27 | 2001-05-03 | Innogenetics N.V. | Redox reversible hcv proteins with native-like conformation |
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US6740323B1 (en) * | 1999-11-24 | 2004-05-25 | Chiron Corporation | HBV/HCV virus-like particle |
JP2002030098A (ja) * | 2000-07-17 | 2002-01-29 | Institute Of Immunology Co Ltd | バキュロウィルスの発芽ウイルスからウイルスエンベロープを回収する方法 |
US7101561B2 (en) | 2000-12-01 | 2006-09-05 | Innogenetics N.V. | Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use |
US7211414B2 (en) * | 2000-12-01 | 2007-05-01 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
BR0203518A (pt) * | 2001-01-11 | 2002-12-17 | Innogenetics Nv | Proteìnas purificadas do envelope do vìrus de hepatite c para uso diagnóstico e terapêutico |
ATE425187T1 (de) * | 2001-01-12 | 2009-03-15 | Molecules Of Man Ab | Materialien und methoden zur behandlung von hepatitis c |
US7048930B2 (en) * | 2001-04-24 | 2006-05-23 | Innogenetics N.V. | Expression of core-glycosylated HCV envelope proteins in yeast |
NZ530632A (en) * | 2001-06-29 | 2007-04-27 | Chiron Corp | HCV E1E2 vaccine compositions comprising E1E2 antigens, submicron oil-in-water emulsions and/or CpG oligonucleotides |
US20040126395A1 (en) * | 2001-12-18 | 2004-07-01 | Geert Maertens | Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use |
US7439042B2 (en) * | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
CN100395263C (zh) * | 2003-01-31 | 2008-06-18 | 欧加农股份有限公司 | 缺氧条件下的蛋白质分离方法 |
US7524650B2 (en) * | 2003-04-01 | 2009-04-28 | Inserm | Antibodies directed against hepatitis C virus E1E2 complex, compositions of HCV particles, and pharmaceutical compositions |
US7788040B2 (en) * | 2003-12-19 | 2010-08-31 | Siemens Medical Solutions Usa, Inc. | System for managing healthcare data including genomic and other patient specific information |
JP4885476B2 (ja) * | 2004-05-21 | 2012-02-29 | 株式会社日本触媒 | タンパク質及び/又はペプチドの細胞内導入方法 |
EP1809773B1 (de) * | 2004-10-18 | 2014-07-16 | Globeimmune, Inc. | Therapeutikum auf hefebasis gegen chronische hepatitis-c-infektion |
US20060292647A1 (en) * | 2004-12-03 | 2006-12-28 | Green Lawrence R | Reflex supplemental testing - A rapid, efficient and highly accurate method to identify subjects with an infection, disease or other condition |
US20080124738A1 (en) * | 2005-03-01 | 2008-05-29 | Pritest, Inc | Compositions and methods of testing for tuberculosis and mycobacterium infection |
JP2008151505A (ja) * | 2005-04-05 | 2008-07-03 | Biomarker Science:Kk | インターフェロン療法の有効性判定方法及び判定用キット |
WO2008025067A1 (en) * | 2006-08-30 | 2008-03-06 | Hepgenics Pty Ltd | Recombinant proteins and virus like particles comprising l and s polypeptides of avian hepadnaviridae and methods, nucleic acid constructs, vectors and host cells for producing same |
US20100286070A1 (en) * | 2007-09-14 | 2010-11-11 | Gert Verheyden | Affinity tag |
US20110091495A1 (en) * | 2008-04-22 | 2011-04-21 | Rutgers, The State University Of New Jersey | Hcv e2 construct compositions and methods |
US9758794B2 (en) | 2008-04-22 | 2017-09-12 | Rutgers, The State University Of New Jersey | HCV E2 construct compositions and methods |
JP2012503011A (ja) | 2008-09-19 | 2012-02-02 | グローブイミューン,インコーポレイテッド | 慢性c型肝炎ウイルス感染の免疫療法 |
US20100104555A1 (en) * | 2008-10-24 | 2010-04-29 | The Scripps Research Institute | HCV neutralizing epitopes |
WO2010111687A2 (en) | 2009-03-27 | 2010-09-30 | Academia Sinica | Methods and compositions for immunization against virus |
WO2011100508A2 (en) * | 2010-02-12 | 2011-08-18 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Methods and compositions related to glycoprotein-immunoglobulin fusions |
WO2011147863A1 (en) | 2010-05-25 | 2011-12-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Combination of anti-envelope antibodies and anti-receptor antibodies for the treatment and prevention of hcv infection |
WO2012162137A1 (en) * | 2011-05-20 | 2012-11-29 | Emory University | Hepatitis c virus particles, vaccines, compositions and methods related thereto |
TW201346040A (zh) * | 2012-03-30 | 2013-11-16 | Tanaka Precious Metal Ind | 流行性感冒a型病毒檢驗用套組 |
CA2886063C (en) | 2012-09-27 | 2021-11-02 | Msd Consumer Care, Inc. | Foaming skincare formulations |
US20170242010A1 (en) * | 2014-02-11 | 2017-08-24 | The Regents Of The University Of California | Combo-Hepatitis Antigen Assays and Kits for Detection of Active Hepatitis Virus Infections |
AU2017214685B2 (en) * | 2016-02-05 | 2024-03-07 | The Board Of Regents Of The University Of Texas System | EGFL6 specific monoclonal antibodies and methods of their use |
US11236153B2 (en) | 2016-09-23 | 2022-02-01 | Emory University | Compositions and methods for identifying and sorting antigen-specific B cells |
EP3519424A4 (de) * | 2016-09-29 | 2020-06-03 | Macfarlane Burnet Institute for Medical Research and Public Health Limited | Assemblierte glykoproteine |
CN109160942B (zh) * | 2018-09-26 | 2021-06-29 | 广州市第八人民医院 | Hcv包膜蛋白高度保守区域的肽段502-518及其用途 |
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DE69131882T3 (de) * | 1990-11-08 | 2007-05-24 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Asiloglycoproteine des hepatitis c-virus |
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DE69225960T2 (de) * | 1991-01-31 | 1999-01-21 | Abbott Laboratories, Abbott Park, Ill. | Monoklonale antikörper gegen mögliche hcv-hüllregionen und methoden diese zu benutzen |
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1995
- 1995-07-31 ES ES95930434T patent/ES2174957T5/es not_active Expired - Lifetime
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- 1995-07-31 EP EP02003643A patent/EP1211315A1/de not_active Withdrawn
- 1995-07-31 BR BR9506059A patent/BR9506059A/pt not_active IP Right Cessation
- 1995-07-31 DE DE69526636T patent/DE69526636T3/de not_active Expired - Lifetime
- 1995-07-31 AT AT95930434T patent/ATE217345T1/de not_active IP Right Cessation
- 1995-07-31 EP EP07109345A patent/EP1845108A3/de not_active Withdrawn
- 1995-07-31 DE DE69526636A patent/DE69526636D1/de not_active Expired - Fee Related
- 1995-07-31 US US08/612,973 patent/US6150134A/en not_active Expired - Fee Related
- 1995-07-31 CA CA002172273A patent/CA2172273A1/en not_active Abandoned
- 1995-07-31 JP JP8506189A patent/JPH09503396A/ja not_active Withdrawn
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- 1995-07-31 DK DK95930434T patent/DK0721505T4/da active
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