ATE139439T1 - Pharmazeutische formulierung und pharmazeutisches verfahren - Google Patents

Pharmazeutische formulierung und pharmazeutisches verfahren

Info

Publication number
ATE139439T1
ATE139439T1 AT92922779T AT92922779T ATE139439T1 AT E139439 T1 ATE139439 T1 AT E139439T1 AT 92922779 T AT92922779 T AT 92922779T AT 92922779 T AT92922779 T AT 92922779T AT E139439 T1 ATE139439 T1 AT E139439T1
Authority
AT
Austria
Prior art keywords
pharmaceutical
formulation
solid phase
cyclosporin
solution
Prior art date
Application number
AT92922779T
Other languages
English (en)
Inventor
Jill P Adler-Moore
William A Ernst
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE139439T1 publication Critical patent/ATE139439T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92922779T 1991-04-19 1992-04-20 Pharmazeutische formulierung und pharmazeutisches verfahren ATE139439T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68781291A 1991-04-19 1991-04-19

Publications (1)

Publication Number Publication Date
ATE139439T1 true ATE139439T1 (de) 1996-07-15

Family

ID=24761958

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92922779T ATE139439T1 (de) 1991-04-19 1992-04-20 Pharmazeutische formulierung und pharmazeutisches verfahren

Country Status (11)

Country Link
US (3) US5688525A (de)
EP (1) EP0580817B1 (de)
JP (1) JP2721041B2 (de)
AT (1) ATE139439T1 (de)
AU (1) AU657961B2 (de)
CA (1) CA2108288C (de)
DE (1) DE69211691T2 (de)
DK (1) DK0580817T3 (de)
ES (1) ES2088160T3 (de)
GR (1) GR3020396T3 (de)
WO (1) WO1992018104A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0697214A1 (de) * 1994-07-19 1996-02-21 Vestar, Inc. Pharmazeutische Formulierungen mit liposomalem Cyclosporin
ATE205723T1 (de) * 1994-11-04 2001-10-15 Polymun Scient Immunbio Forsch Applikation von sod in liposomen
US5693336A (en) * 1995-06-07 1997-12-02 Nexstar Pharmaceuticals, Inc. Blood stable liposomal cyclosporin formulations
AU6047996A (en) * 1995-06-07 1996-12-30 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppr ession and multiple drug resistant indications
CA2202103C (en) 1996-04-11 2007-01-09 Toshiaki Tagawa Method for preparing closed vesicles
DK1154759T3 (da) 1998-12-30 2008-12-08 Dexcel Ltd Dispergerbart koncentrat til indgift af cyclosporin
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
KR20020070346A (ko) * 2000-01-20 2002-09-05 바실리어 파마슈티카 아게 비강 투여 가능 고리형 펩티드 조성물
US7125568B2 (en) * 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
BR0213661A (pt) * 2001-10-19 2004-10-26 Isotechnika Inc Pré-concentrado de microemulsão e método para seu preparo, formulação farmacêutica e método para seu preparo, método para produzir imuno, supressão, método para aumentar os efeitos imuno supressores de isatx247, uso de formulação farmacêutica
US7179484B2 (en) * 2002-11-06 2007-02-20 Azaya Therapeutics, Inc. Protein-stabilized liposomal formulations of pharmaceutical agents
WO2006014035A1 (en) * 2004-08-06 2006-02-09 Biospectrum, Inc. Multiple layered liposome and preparation method thereof
US20060165641A1 (en) * 2005-01-18 2006-07-27 Kumar Pillai Cosmetic compositions containing combinations of hydroxamate derivatives and antioxidants in a liposomal delivery system
US20070026061A1 (en) * 2005-05-25 2007-02-01 Nahid Ali Liposomal formulation and use thereof
KR20080065704A (ko) 2005-11-09 2008-07-14 콤비네이토릭스, 인코포레이티드 의학적 이상의 치료 방법들, 조성물들, 및 키트들
JPWO2008026781A1 (ja) * 2006-08-31 2010-01-21 直人 奥 逆標的化脂質小胞体
ES2630036T3 (es) 2008-03-06 2017-08-17 Anacor Pharmaceuticals, Inc. Moléculas pequeñas que contienen boro como agentes antiinflamatorios
US8218847B2 (en) 2008-06-06 2012-07-10 Superdimension, Ltd. Hybrid registration method
AU2010271269B2 (en) 2009-07-10 2016-09-08 Childrens' Medical Center Corporation Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
EP2512240B1 (de) 2009-12-18 2018-04-11 Achelios Therapeutics, Inc. Verfahren und zusammensetzungen zur behandlung und prävention von trigeminoautonomen zephalgien, migräne und gefässerkrankungen
US8716478B2 (en) 2010-01-27 2014-05-06 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
ES2830385T3 (es) 2014-09-12 2021-06-03 Genentech Inc Anticuerpos e inmunoconjugados anti-HER2
US20170266106A1 (en) 2014-12-01 2017-09-21 Achelios Therapeutics, Inc. Methods and compositions for treating migraine and conditions associated with pain
RU2018107695A (ru) 2015-08-03 2019-09-05 Президент Энд Феллоуз Оф Гарвард Колледж Заряженные блокаторы ионных каналов и способы их применения
JP2019532027A (ja) 2016-08-17 2019-11-07 ソルスティス バイオロジクス，リミティッド ポリヌクレオチド構築物
US11597744B2 (en) 2017-06-30 2023-03-07 Sirius Therapeutics, Inc. Chiral phosphoramidite auxiliaries and methods of their use
JP7401471B2 (ja) 2018-06-27 2023-12-19 ブレス テラポイティクス ゲーエムベーハー 凍結乾燥形態の医薬組成物
AU2020239060A1 (en) 2019-03-11 2021-09-30 Nocion Therapeutics, Inc. Ester substituted ion channel blockers and methods for use
WO2020185881A1 (en) 2019-03-11 2020-09-17 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
MX2021010870A (es) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueadores de canales ionicos cargados y metodos de uso.
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US20220307013A1 (en) 2019-08-30 2022-09-29 The Regents Of The University Of California Gene fragment overexpression screening methodologies, and uses thereof
CA3155568A1 (en) 2019-11-06 2021-05-14 Bridget Mccarthy Cole Charged ion channel blockers and methods for use
MX2022005335A (es) 2019-11-06 2022-08-17 Nocion Therapeutics Inc Bloqueadores de canales ionicos cargados y metodos de uso.
BR112022017801A2 (pt) 2020-03-11 2022-10-25 Nocion Therapeutics Inc Bloqueadores de canais de íons carregados e métodos para uso
WO2022243866A1 (en) * 2021-05-17 2022-11-24 Mahmoud Reza Jaafari Method for producing liposomes entrapping cyclosporine a

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663167A (en) * 1984-04-16 1987-05-05 The Board Of Regents Of The University Of Texas System Composition and method for treatment of disseminated fungal infections in mammals
US4797285A (en) * 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
US5023087A (en) * 1986-02-10 1991-06-11 Liposome Technology, Inc. Efficient method for preparation of prolonged release liposome-based drug delivery system
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
US5000887A (en) * 1988-05-17 1991-03-19 Liposome Technology, Inc. Preparation of uniform-size liposomes
US4952405A (en) * 1988-10-20 1990-08-28 Liposome Technology, Inc. Method of treating M. avium infection
WO1991004019A1 (en) * 1989-09-12 1991-04-04 The Regents Of The University Of California Therapeutic peptides and proteins

Also Published As

Publication number Publication date
AU1797792A (en) 1992-11-17
US5660856A (en) 1997-08-26
CA2108288A1 (en) 1992-10-20
DE69211691D1 (de) 1996-07-25
JP2721041B2 (ja) 1998-03-04
WO1992018104A1 (en) 1992-10-29
US5688525A (en) 1997-11-18
DK0580817T3 (da) 1996-08-05
EP0580817B1 (de) 1996-06-19
ES2088160T3 (es) 1996-08-01
US5670166A (en) 1997-09-23
DE69211691T2 (de) 1997-01-16
AU657961B2 (en) 1995-03-30
JPH06510024A (ja) 1994-11-10
GR3020396T3 (en) 1996-09-30
CA2108288C (en) 2003-09-16
EP0580817A1 (de) 1994-02-02

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UEP Publication of translation of european patent specification