AT554074T - Process for preparing 4'-ae4-methyl-6- (1-methyl-1h-benzimidazole-2-yl) -2-propyl-1h- - Google Patents

Process for preparing 4'-ae4-methyl-6- (1-methyl-1h-benzimidazole-2-yl) -2-propyl-1h-

Info

Publication number
AT554074T
AT554074T AT08773249T AT08773249T AT554074T AT 554074 T AT554074 T AT 554074T AT 08773249 T AT08773249 T AT 08773249T AT 08773249 T AT08773249 T AT 08773249T AT 554074 T AT554074 T AT 554074T
Authority
AT
Austria
Prior art keywords
methyl
benzimidazole
propyl
preparing
Prior art date
Application number
AT08773249T
Other languages
German (de)
Inventor
Jan Stach
Stanislav Radl
Josef Cinibulk
Ivo Strelec
Kamal Jarrah
Original Assignee
Zentiva K S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CZ20070457A priority Critical patent/CZ302272B6/en
Application filed by Zentiva K S filed Critical Zentiva K S
Priority to PCT/CZ2008/000080 priority patent/WO2009006860A2/en
Publication of AT554074T publication Critical patent/AT554074T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14Radicals substituted by nitrogen atoms
AT08773249T 2007-07-09 2008-07-08 Process for preparing 4'-ae4-methyl-6- (1-methyl-1h-benzimidazole-2-yl) -2-propyl-1h- AT554074T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CZ20070457A CZ302272B6 (en) 2007-07-09 2007-07-09 Process for preparing 4?-[[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1yl]methyl]biphenyl-2-carboxylic acid (telmisartan)
PCT/CZ2008/000080 WO2009006860A2 (en) 2007-07-09 2008-07-08 A method of manufacturing 4'-[[4-methyl-6-(1-methyl-1h-benzimidazol-2-yl)-2-propyl-1h-benzimidazol-1yl]methyl]biphenyl-2-carboxylic acid (telmisartan)

Publications (1)

Publication Number Publication Date
AT554074T true AT554074T (en) 2012-05-15

Family

ID=40229130

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08773249T AT554074T (en) 2007-07-09 2008-07-08 Process for preparing 4'-ae4-methyl-6- (1-methyl-1h-benzimidazole-2-yl) -2-propyl-1h-

Country Status (13)

Country Link
US (1) US20100222402A1 (en)
EP (1) EP2176235B1 (en)
AT (1) AT554074T (en)
CZ (1) CZ302272B6 (en)
EA (1) EA015790B1 (en)
ES (1) ES2386678T3 (en)
HR (1) HRP20120501T1 (en)
PL (1) PL2176235T3 (en)
PT (1) PT2176235E (en)
RS (1) RS52426B (en)
SI (1) SI2176235T1 (en)
UA (1) UA99140C2 (en)
WO (1) WO2009006860A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010004385A1 (en) * 2008-06-17 2010-01-14 Aurobindo Pharma Limited Process for the preparation of pure 4'-[4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl]methyl]-2-biphenylcarboxylic acid
WO2010018441A2 (en) * 2008-08-11 2010-02-18 Cadila Pharmaceuticals Ltd. An improved process for the preparation of substantially pure telmisartan
EP2632438A1 (en) 2010-10-27 2013-09-04 KRKA, tovarna zdravil, d.d., Novo mesto Multilayer pharmaceutical composition comprising telmisartan and amlodipine
ITMI20102416A1 (en) * 2010-12-27 2012-06-28 Chemelectiva S R L Intermediate for the preparation of an active ingredient and the process for its preparation
JP6147546B2 (en) * 2013-04-10 2017-06-14 株式会社トクヤマ Method for producing telmisartan A-type crystals with reduced acetic acid

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614519A (en) * 1991-02-06 1997-03-25 Karl Thomae Gmbh (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists
US6358986B1 (en) * 1999-01-19 2002-03-19 Boehringer Ingelheim Pharma Kg Polymorphs of telmisartan
DE10314702A1 (en) * 2003-03-31 2004-10-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for the preparation of telmisartan
GB2414019A (en) 2004-05-11 2005-11-16 Cipla Ltd One-step preparation of telmisartan by condensation and hydrolysis
CN101039917A (en) * 2004-10-15 2007-09-19 特瓦制药工业有限公司 Process for preparing telmisartan
WO2006044754A2 (en) * 2004-10-18 2006-04-27 Dr. Reddy's Laboratories Ltd. Process for preparing telmisartan
US20060211866A1 (en) * 2005-03-21 2006-09-21 Glenmark Pharmaceuticals Limited Process for the preparation of angiotensin receptor blockers and intermediates thereof

Also Published As

Publication number Publication date
EP2176235B1 (en) 2012-04-18
EA201000065A1 (en) 2010-06-30
CZ2007457A3 (en) 2009-02-11
WO2009006860A3 (en) 2009-04-16
CZ302272B6 (en) 2011-01-19
EP2176235A2 (en) 2010-04-21
EA015790B1 (en) 2011-12-30
PT2176235E (en) 2012-07-02
UA99140C2 (en) 2012-07-25
HRP20120501T1 (en) 2012-10-31
US20100222402A1 (en) 2010-09-02
RS52426B (en) 2013-02-28
SI2176235T1 (en) 2012-10-30
ES2386678T3 (en) 2012-08-24
WO2009006860A2 (en) 2009-01-15
PL2176235T3 (en) 2012-09-28

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