AT543T - Diagnostic agent, method for the production thereof and the use thereof for detecting leucocytes in body liquids. - Google Patents

Diagnostic agent, method for the production thereof and the use thereof for detecting leucocytes in body liquids.

Info

Publication number
AT543T
AT543T AT80100671T AT80100671T AT543T AT 543 T AT543 T AT 543T AT 80100671 T AT80100671 T AT 80100671T AT 80100671 T AT80100671 T AT 80100671T AT 543 T AT543 T AT 543T
Authority
AT
Austria
Prior art keywords
leucocytes
liquids
detecting
production
diagnostic agent
Prior art date
Application number
AT80100671T
Other languages
German (de)
Inventor
Dieter Dr.Rer.Nat. Berger
Guenter Frey
Manfred Dr.Rer.Nat. Kuhr
Wolfgang Dr.Rer.Nat. Werner
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19792905531 priority Critical patent/DE2905531A1/en
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Priority to EP80100671A priority patent/EP0014929B1/en
Publication of AT543T publication Critical patent/AT543T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00Diaryl- or thriarylmethane dyes
    • C09B11/04Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/06Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
    • C09B11/08Phthaleins; Phenolphthaleins; Fluorescein
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B43/00Preparation of azo dyes from other azo compounds
    • C09B43/18Preparation of azo dyes from other azo compounds by acylation of hydroxyl group or of mercapto group
    • C09B43/20Preparation of azo dyes from other azo compounds by acylation of hydroxyl group or of mercapto group with monocarboxylic acids, carbamic acid esters or halides, mono- isocyanates or haloformic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/40Triphenylmethane dye chromogens, e.g. fluorescein derivatives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/50Indoles
AT80100671T 1979-02-14 1980-02-11 Diagnostic agent, method for the production thereof and the use thereof for detecting leucocytes in body liquids. AT543T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE19792905531 DE2905531A1 (en) 1979-02-14 1979-02-14 DIAGNOSTIC AGENT FOR DETECTING LEUCOCYTES IN BODY LIQUIDS
EP80100671A EP0014929B1 (en) 1979-02-14 1980-02-11 Diagnostic means, process for its preparation and its use in determining leucocytes in body fluids

Publications (1)

Publication Number Publication Date
AT543T true AT543T (en) 1982-01-15

Family

ID=6062854

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80100671T AT543T (en) 1979-02-14 1980-02-11 Diagnostic agent, method for the production thereof and the use thereof for detecting leucocytes in body liquids.

Country Status (23)

Country Link
US (1) US4299917A (en)
EP (1) EP0014929B1 (en)
JP (1) JPS581920B2 (en)
AR (1) AR223025A1 (en)
AT (1) AT543T (en)
AU (1) AU519912B2 (en)
BR (1) BR8000886A (en)
CA (1) CA1148073A (en)
CS (1) CS216523B2 (en)
DD (1) DD149121A5 (en)
DE (2) DE2905531A1 (en)
DK (1) DK161340C (en)
ES (1) ES8102726A1 (en)
FI (1) FI69869C (en)
HK (1) HK15285A (en)
HU (1) HU182102B (en)
MY (1) MY102785A (en)
PL (1) PL125796B1 (en)
PT (1) PT70813A (en)
RU (1) RU1784097C (en)
SG (1) SG79484G (en)
YU (2) YU45527B (en)
ZA (2) ZA8000765B (en)

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DE3017721A1 (en) * 1980-05-09 1981-11-26 Boehringer Mannheim Gmbh AGENT FOR DETECTING ESTEROLYTIC AND / OR PROTEOLYTIC ENZYME AND SUBSTRATES SUITABLE FOR THIS
DE3118381A1 (en) * 1981-05-09 1982-11-25 Boehringer Mannheim Gmbh MULTILAYER TEST MEANS FOR DETECTING A COMPONENT OF A LIQUID SAMPLE
DE3211254A1 (en) * 1982-03-26 1983-09-29 Boehringer Mannheim Gmbh METHOD FOR DETECTING THE PRESENCE OF AN ALLERGY AND FOR SPECIFIC DETECTING THE ALLERGY RESPONSIBLE FOR THE ALLERGY
US4499185A (en) * 1982-05-17 1985-02-12 Miles Laboratories, Inc. Test for esterase activity in a liquid sample
DE3309544A1 (en) * 1983-03-17 1984-09-20 Macherey Nagel & Co Chem TEST STRIP FOR DETECTING LEUCOCYTES IN THE URIN
DE3413119A1 (en) * 1984-04-06 1985-10-24 Miles Lab ANALYSIS METHOD AND MEANS FOR DETECTING ESTEROLYTIC AND / OR PROTEOLYTIC ENZYMS
US4645842A (en) * 1984-04-06 1987-02-24 Miles Laboratories, Inc. Pyrrole compounds for detecting the presence of hydrolytic analytes
DE3413120A1 (en) * 1984-04-06 1985-10-24 Miles Lab ANALYSIS METHOD AND MEANS FOR DETECTING ESTEROLYTIC AND / OR PROTEOLYTIC ENZYMS
US4657855A (en) * 1984-04-06 1987-04-14 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample
US4637979A (en) * 1984-04-06 1987-01-20 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent
DE3413118A1 (en) * 1984-04-06 1985-10-24 Miles Lab ANALYSIS METHOD AND MEANS FOR DETECTING ESTEROLYTIC AND / OR PROTEOLYTIC ENZYMS
DD247808C2 (en) * 1984-04-09 1989-01-11 Dresden Arzneimittel Test strips for receiving blood sugar day profiles and method for the production thereof
DE3587636T2 (en) * 1984-05-31 1994-03-10 Coulter Corp REAGENT SYSTEM AND METHOD FOR DETECTING, LISTING AND CHECKING THE CLASSES AND SUBCLASSES OF BLOOD LEUCOCYTES.
US4672029A (en) * 1984-12-06 1987-06-09 Eastman Kodak Company Color-forming couplers and their use in the analytical determination of hydrogen peroxide or other analytes
US5051358A (en) * 1987-05-07 1991-09-24 The Procter & Gamble Company Diagnostic methods for detecting periodontal diseases
GB8713951D0 (en) * 1987-06-15 1987-07-22 Dewar M H Enhanced chemiluminescent reaction
DE3732871A1 (en) * 1987-09-30 1989-04-20 Behringwerke Ag CHROMOGENEOUS SUBSTRATES
US5192688A (en) * 1988-08-15 1993-03-09 Switzer Iii Robert C Histological analysis method
FR2657895B1 (en) * 1990-02-05 1994-04-22 France Institut Textile
US6046019A (en) * 1991-07-09 2000-04-04 Goumeniouk; Alexander P. Diagnostic kits and methods for making granulocyte cell counts
DE19500768C2 (en) * 1994-01-17 2003-11-20 Aventis Res & Tech Gmbh & Co Phenanthrene derivatives and their use in liquid crystalline mixtures
US5464739A (en) * 1994-08-22 1995-11-07 Bayer Corporation Composition method for determining the presence of leukocyte cells, esterase or protease in a test sample
CA2161574A1 (en) 1994-11-15 1996-05-16 James Noffsinger Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid
DE19651886A1 (en) * 1996-12-13 1998-06-18 Merck Patent Gmbh Means and methods for the determination of hydrolytic enzymes
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
US6528652B1 (en) 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US6709868B2 (en) * 2002-05-20 2004-03-23 Portascience Inc. Method and apparatus for measuring white blood cell count
AU2003261834A1 (en) * 2002-08-30 2004-05-04 Bf Research Institute, Inc. Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US7491699B2 (en) * 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
US6963007B2 (en) 2002-12-19 2005-11-08 3M Innovative Properties Company Diacetylenic materials for sensing applications
US20040126897A1 (en) 2002-12-19 2004-07-01 3M Innovative Properties Company Colorimetric sensors constructed of diacetylene materials
WO2004060791A1 (en) 2003-01-07 2004-07-22 Ramot At Tel Aviv University Ltd. Peptide nanostructures encapsulating a foreign material and method of manufacturing same
CA2530927A1 (en) * 2003-06-30 2005-01-06 Tel Aviv University Future Technology Development L.P. Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
EP1663199B1 (en) * 2003-09-25 2013-04-03 Tel Aviv University Future Technology Development L.P. Compositions and methods using same for treating amyloid-associated diseases
WO2005031362A2 (en) * 2003-10-02 2005-04-07 Ramot At Tel Aviv University Ltd. Novel antibacterial agents and methods of identifying and utilizing same
US20090156471A1 (en) * 2004-07-15 2009-06-18 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
US8568637B2 (en) * 2004-08-02 2013-10-29 Ramot At Tel-Aviv University Ltd. Method of forming a fiber made of peptide nanostructures
US7732479B2 (en) * 2004-08-19 2010-06-08 Tel Aviv University Future Technology Development L.P. Compositions for treating amyloid associated diseases
WO2006027780A2 (en) 2004-09-08 2006-03-16 Ramot At Tel Aviv University Ltd. Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
US20060134796A1 (en) * 2004-12-17 2006-06-22 3M Innovative Properties Company Colorimetric sensors constructed of diacetylene materials
GB2426334A (en) * 2005-05-20 2006-11-22 Orion Diagnostica Oy Application of a reagent to a matrix material
US7504235B2 (en) * 2005-08-31 2009-03-17 Kimberly-Clark Worldwide, Inc. Enzyme detection technique
US8003399B2 (en) * 2005-08-31 2011-08-23 Kimberly-Clark Worldwide, Inc. Nitrite detection technique
EP1973928A2 (en) * 2005-10-11 2008-10-01 Ramot at Tel-Aviv University Ltd. Self-assembled fmoc-ff hydrogels
US7879212B2 (en) * 2005-11-03 2011-02-01 Ramot At Tel-Aviv University Ltd. Peptide nanostructure-coated electrodes
WO2009067595A1 (en) * 2007-11-20 2009-05-28 3M Innovative Properties Company Method of analyzing a sample for a bacterium using diacetylene-containing polymer sensor
US9103796B2 (en) * 2007-12-14 2015-08-11 Kimberly-Clark Worldwide, Inc. Multi-layered devices for analyte detection
WO2020069176A1 (en) * 2018-09-27 2020-04-02 Parvizi Surgical Innovation, Llc Compositions and methods for determining the presence of active leukocyte cells using an electrochemical assay

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Also Published As

Publication number Publication date
FI69869C (en) 1986-05-26
DK63480A (en) 1980-08-15
EP0014929A1 (en) 1980-09-03
ZA80765B (en) 1981-03-25
YU38680A (en) 1989-02-28
HK15285A (en) 1985-03-15
HU182102B (en) 1983-12-28
FI800444A (en) 1980-08-15
DE2905531A1 (en) 1981-01-08
DK161340B (en) 1991-06-24
CA1148073A (en) 1983-06-14
ES8102726A1 (en) 1981-02-16
YU45527B (en) 1992-05-28
EP0014929B1 (en) 1982-01-06
ES488402A0 (en) 1981-02-16
ZA8000765B (en) 1981-03-25
MY102785A (en) 1985-12-31
YU212888A (en) 1990-04-30
PL125796B1 (en) 1983-06-30
AR223025A1 (en) 1981-07-15
CA1148073A1 (en)
JPS55108300A (en) 1980-08-20
DE3060134D1 (en) 1982-02-25
ES488402D0 (en)
US4299917A (en) 1981-11-10
BR8000886A (en) 1980-10-21
CS216523B2 (en) 1982-11-26
SG79484G (en) 1985-08-16
RU1784097C (en) 1992-12-23
DD149121A5 (en) 1981-06-24
AU519912B2 (en) 1982-01-07
FI69869B (en) 1985-12-31
DK161340C (en) 1991-12-02
JPS581920B2 (en) 1983-01-13
AU5535980A (en) 1981-01-15
PL221884A1 (en) 1980-11-03
PT70813A (en) 1980-03-01

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Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time