AT518874T - Synthetic lipid-a analoges and uses thereof - Google Patents

Synthetic lipid-a analoges and uses thereof

Info

Publication number
AT518874T
AT518874T AT00980380T AT00980380T AT518874T AT 518874 T AT518874 T AT 518874T AT 00980380 T AT00980380 T AT 00980380T AT 00980380 T AT00980380 T AT 00980380T AT 518874 T AT518874 T AT 518874T
Authority
AT
Austria
Prior art keywords
analoges
uses
synthetic lipid
lipid
synthetic
Prior art date
Application number
AT00980380T
Other languages
German (de)
Inventor
Zi-Hua Jiang
Mimi Bach
Damayanthi Yalamati
Rao Koganty
Michael Longenecker
Original Assignee
Oncothyreon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US16492899P priority Critical
Application filed by Oncothyreon Inc filed Critical Oncothyreon Inc
Priority to PCT/US2000/031281 priority patent/WO2001036433A2/en
Publication of AT518874T publication Critical patent/AT518874T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06Fatty acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/812Liposome comprising an antibody, antibody fragment, antigen, or other specific or nonspecific immunoeffector
AT00980380T 1999-11-15 2000-11-15 Synthetic lipid-a analoges and uses thereof AT518874T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US16492899P true 1999-11-15 1999-11-15
PCT/US2000/031281 WO2001036433A2 (en) 1999-11-15 2000-11-15 Synthetic lipid-a analogs and uses thereof

Publications (1)

Publication Number Publication Date
AT518874T true AT518874T (en) 2011-08-15

Family

ID=22596692

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00980380T AT518874T (en) 1999-11-15 2000-11-15 Synthetic lipid-a analoges and uses thereof

Country Status (8)

Country Link
US (1) US7491707B1 (en)
EP (1) EP1232168B1 (en)
JP (1) JP2003514824A (en)
AT (1) AT518874T (en)
AU (1) AU780577B2 (en)
CA (1) CA2396744C (en)
ES (1) ES2370262T3 (en)
WO (1) WO2001036433A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60215627T2 (en) 2001-03-27 2007-07-19 Biomira, Inc., Edmonton Vaccinator for modulation between t1 and t2 immune responses
EP1572918B1 (en) * 2002-04-15 2011-10-19 Oncothyreon Inc. Synthetic glyco-lipo-peptides as vaccines
ES2343788T3 (en) 2002-05-09 2010-08-10 Oncothyreon Inc. Analogs of lipido a and other glucidical links.
TW200403250A (en) * 2002-06-18 2004-03-01 Sankyo Co Glucoxyl lipid A1-carboxymethyl compounds
AU2002950657A0 (en) * 2002-08-08 2002-09-12 Alchemia Limited Derivatives of monosaccharides for drug discovery
AU2002951995A0 (en) 2002-10-11 2002-10-31 Alchemia Limited Classes of compounds that interact with gpcrs
US7960522B2 (en) * 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
RU2389732C2 (en) * 2003-01-06 2010-05-20 Корикса Корпорейшн Certain aminoalkyl glucosaminide phospahte derivatives and use thereof
EP1547581A1 (en) * 2003-12-23 2005-06-29 Vectron Therapeutics AG Liposomal vaccine for the treatment of human hematological malignancies
TW201204410A (en) 2004-04-01 2012-02-01 Oncothyreon Inc Mucinous glycoprotein (MUC-1) vaccine
HUE026490T2 (en) 2005-06-28 2016-06-28 Oncothyreon Inc Method of treating patients with a mucinous glycoprotein (MUC-1) vaccine
EP1803814A1 (en) 2005-12-27 2007-07-04 SIGMA TAU Industrie Farmaceutiche Riunite S.p.A. Method of improving the antibody selection capacity in phage-display library
PL2484375T3 (en) 2006-09-26 2018-09-28 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
WO2008059307A2 (en) * 2006-11-16 2008-05-22 Om Pharma Functionalized beta 1,6 glucosamine disaccharides and process for their preparation
CN105935352A (en) * 2008-12-17 2016-09-14 肿瘤防护公司 Method of making small liposomes
CA2764374C (en) 2009-06-05 2019-11-19 Infectious Disease Research Institute Synthetic glucopyranosyl lipid adjuvants
CN103209701B (en) * 2010-06-11 2016-08-03 乔治亚大学研究基金公司 Immunogenicity of the vaccine
KR20140023903A (en) 2011-02-24 2014-02-27 온코타이레온, 인코포레이티드 Muc1 based glycolipopeptide vaccine with adjuvant
WO2012141984A1 (en) 2011-04-08 2012-10-18 Immune Design Corp. Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
EP2780350B1 (en) 2011-11-18 2019-03-06 Variation Biotechnologies Inc. Synthetic derivatives of mpl and uses thereof
US9241988B2 (en) 2012-04-12 2016-01-26 Avanti Polar Lipids, Inc. Disaccharide synthetic lipid compounds and uses thereof
US9518078B2 (en) 2012-04-12 2016-12-13 Avanti Polar Lipids, Inc. Disaccharide synthetic lipid compounds and uses thereof
HUE039215T2 (en) 2012-05-16 2018-12-28 Immune Design Corp Vaccines for hsv-2
JP6426706B2 (en) 2013-04-18 2018-11-21 イミューン デザイン コーポレイション GLA monotherapy for use in cancer treatment
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
WO2016109880A1 (en) * 2015-01-06 2016-07-14 Immunovaccine Technologies Inc. Lipid a mimics, methods of preparation, and uses thereof

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US5554372A (en) * 1986-09-22 1996-09-10 Emory University Methods and vaccines comprising surface-active copolymers
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5134230A (en) * 1988-03-02 1992-07-28 Daiichi Pharmaceutical Co., Ltd. 2-Deoxy-2-aminoglucopyranoside derivatives
ZA8801430B (en) 1988-03-02 1988-10-28
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5481021A (en) * 1991-03-06 1996-01-02 G. D. Searle & Co. Phenyl amidines derivatives useful as platelet aggregation inhibitors
AU660325B2 (en) 1991-10-11 1995-06-22 Eisai Co. Ltd. Anti-endotoxin compounds and related molecules and methods
PL181241B1 (en) * 1993-11-17 2001-06-29 Laboratoires Om S.A. Glucosoamine disaccharides, method of obtaining them and pharmaceutical composition containing them as well as their application
US5648343A (en) * 1994-02-28 1997-07-15 The University Of Georgia Research Foundation Method for treating LPS-mediated disorders
CA2189356A1 (en) 1994-05-02 1995-11-09 Ting Chi Wong Process for preparation of glycosides of tumor-associated carbohydrate antigens
US6887483B2 (en) * 1995-12-01 2005-05-03 University Of Iowa Research Foundation Non-toxic mutants of pathogenic gram-negative bacteria
WO1998033810A2 (en) 1997-01-30 1998-08-06 University Of Virginia Patent Foundation Cysteine-depleted peptides recognized by a3-restricted cytotoxic lymphocytes, and uses therefor

Also Published As

Publication number Publication date
EP1232168A2 (en) 2002-08-21
AU780577B2 (en) 2005-04-07
CA2396744A1 (en) 2001-05-25
WO2001036433A2 (en) 2001-05-25
ES2370262T3 (en) 2011-12-14
CA2396744C (en) 2011-07-12
JP2003514824A (en) 2003-04-22
WO2001036433A3 (en) 2002-05-10
US7491707B1 (en) 2009-02-17
EP1232168B1 (en) 2011-08-03
AU1764701A (en) 2001-05-30

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties