AT516304T - Nrg-2 nucleic acids, polypeptides, and diagnostic / therapeutic methods - Google Patents

Nrg-2 nucleic acids, polypeptides, and diagnostic / therapeutic methods

Info

Publication number
AT516304T
AT516304T AT01941609T AT01941609T AT516304T AT 516304 T AT516304 T AT 516304T AT 01941609 T AT01941609 T AT 01941609T AT 01941609 T AT01941609 T AT 01941609T AT 516304 T AT516304 T AT 516304T
Authority
AT
Austria
Prior art keywords
nrg
polypeptides
diagnostic
nucleic acids
therapeutic methods
Prior art date
Application number
AT01941609T
Other languages
German (de)
Inventor
Mark Marchionni
Original Assignee
Cenes Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US20649500P priority Critical
Application filed by Cenes Pharmaceuticals Inc filed Critical Cenes Pharmaceuticals Inc
Priority to PCT/US2001/016896 priority patent/WO2001089568A1/en
Publication of AT516304T publication Critical patent/AT516304T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/4756Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
AT01941609T 2000-05-23 2001-05-23 Nrg-2 nucleic acids, polypeptides, and diagnostic / therapeutic methods AT516304T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US20649500P true 2000-05-23 2000-05-23
PCT/US2001/016896 WO2001089568A1 (en) 2000-05-23 2001-05-23 Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods

Publications (1)

Publication Number Publication Date
AT516304T true AT516304T (en) 2011-07-15

Family

ID=22766650

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01941609T AT516304T (en) 2000-05-23 2001-05-23 Nrg-2 nucleic acids, polypeptides, and diagnostic / therapeutic methods

Country Status (12)

Country Link
US (5) US6890751B2 (en)
EP (2) EP2357004B1 (en)
JP (5) JP5324732B2 (en)
AT (1) AT516304T (en)
AU (2) AU2001274947B2 (en)
BR (1) BR0111125A (en)
CA (2) CA2409996C (en)
ES (2) ES2370875T3 (en)
IL (2) IL153052D0 (en)
MX (1) MXPA02011656A (en)
WO (1) WO2001089568A1 (en)
ZA (1) ZA200210085B (en)

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AT516304T (en) 2000-05-23 2011-07-15 Cenes Pharmaceuticals Inc Nrg-2 nucleic acids, polypeptides, and diagnostic / therapeutic methods
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
SI1842533T1 (en) * 2003-08-06 2013-06-28 Grunenthal Gmbh Dosage form that is secured against misuse
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10336400A1 (en) * 2003-08-06 2005-03-24 Grünenthal GmbH Abuse-proofed dosage form
DE10361596A1 (en) * 2003-12-24 2005-09-29 Grünenthal GmbH A process for preparing a secured against misuse dosage form
DE102004020220A1 (en) * 2004-04-22 2005-11-10 Grünenthal GmbH A process for preparing a secured against misuse, solid dosage form
DE102004032103A1 (en) * 2004-07-01 2006-01-19 Grünenthal GmbH Abuse-proofed, oral dosage form
DE102004032049A1 (en) * 2004-07-01 2006-01-19 Grünenthal GmbH Abuse-proofed, oral dosage form
DE102005005446A1 (en) * 2005-02-04 2006-08-10 Grünenthal GmbH Unbreakable dosage forms with delayed release
DE102005005449A1 (en) * 2005-02-04 2006-08-10 Grünenthal GmbH A process for preparing a secured against misuse dosage form
EP1890722A2 (en) * 2005-05-27 2008-02-27 Five Prime Therapeutics, Inc. Methods of and compositions for stimulation of glucose uptake into muscle cells and treatment of diseases
CA2634974A1 (en) * 2005-12-30 2007-07-12 Zensun (Shanghai) Science & Technology, Ltd. Extended release of neuregulin for improved cardiac function
DE102007011485A1 (en) * 2007-03-07 2008-09-11 Grünenthal GmbH Dosage form with impeded abuse
TWI454288B (en) 2008-01-25 2014-10-01 Gruenenthal Chemie Pharmaceutical dosage form
CA2723438C (en) * 2008-05-09 2016-10-11 Gruenenthal Gmbh Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
DK2320933T3 (en) 2008-07-17 2018-04-16 Acorda Therapeutics Inc A therapeutic dosage of a neuregulin or a subsequence thereof for the treatment or prophylaxis of heart failure
CN102159237A (en) 2008-08-15 2011-08-17 阿索尔达治疗公司 Compositions and methods for treatment during non-acute periods following cns neurological injury
US8609620B2 (en) 2008-11-28 2013-12-17 Zensun (Shanghai) Science & Technology Ltd. Neuregulin peptides and their use
CN102231987A (en) * 2008-11-28 2011-11-02 上海泽生科技开发有限公司 Neuregulin and cardiac stem cells
PE10672012A1 (en) * 2009-07-22 2012-09-05 Gruenenthal Chemie Form of controlled release dosage extruded by hot melt
EP2456424B1 (en) 2009-07-22 2013-08-28 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
NZ625673A (en) * 2009-10-14 2015-11-27 Acorda Therapeutics Inc Use of a neuregulin to treat peripheral nerve injury
EP2555789A1 (en) * 2010-04-08 2013-02-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Inhibiting peptides derived from trem-like transcript 1 (tlt-1) and uses thereof
KR20130097202A (en) 2010-09-02 2013-09-02 그뤼넨탈 게엠베하 Tamper resistant dosage form comprising inorganic salt
JP5933553B2 (en) 2010-09-02 2016-06-15 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Abuse-resistant dosage form comprising an anionic polymer
HUE034711T2 (en) 2011-07-29 2018-02-28 Gruenenthal Gmbh Tamper-resistant tablet providing immediate drug release
US20130225697A1 (en) 2012-02-28 2013-08-29 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
NZ700546A (en) * 2012-03-30 2017-05-26 Acorda Therapeutics Inc Use of neuregulin to treat peripheral nerve injury
DK2838512T3 (en) 2012-04-18 2018-11-19 Gruenenthal Gmbh Tamper-proof and dose dumping secured pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
CN104918950B (en) * 2012-12-27 2018-10-12 丝芭博株式会社 A hydrophilic partially purified recombinant protein
WO2014103846A1 (en) * 2012-12-27 2014-07-03 スパイバー株式会社 Extraction method for hydrophilic recombinant protein
US9968682B2 (en) 2013-04-25 2018-05-15 Spiber Inc. Polypeptide hydrogel and method for producing same
JP5796147B2 (en) 2013-04-25 2015-10-21 Spiber株式会社 Polypeptide porous body and manufacturing method thereof
JP6445537B2 (en) 2013-05-29 2018-12-26 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Modified anti containing one or more particles (tamper-resistant) dosage forms
CA2913209A1 (en) 2013-05-29 2014-12-04 Grunenthal Gmbh Tamper resistant dosage form with bimodal release profile
CA2913074A1 (en) 2013-05-30 2014-12-04 Graham H. Creasey Topical neurological stimulation
JP2017518980A (en) 2014-05-12 2017-07-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Containing tapentadol, modified prevent immediate release capsule formulation
MX2016015417A (en) 2014-05-26 2017-02-22 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping.
KR20170139158A (en) 2015-04-24 2017-12-18 그뤼넨탈 게엠베하 Immediately released and prevent the tamper-resistant dosage form extraction solvent
AU2016327974A1 (en) 2015-09-25 2018-04-12 Douglas B. Sawyer Methods for treating cardiac injury
CN108778315A (en) * 2016-04-19 2018-11-09 莱布尼茨研究所-针对老化研究(弗里茨利普曼研究所) Neuregulin for the treatment and/or prevention of tumors of the nervous system

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US5843463A (en) 1990-12-21 1998-12-01 Antexbiologics, Inc. Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae
US6087323A (en) * 1992-04-03 2000-07-11 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US7115554B1 (en) * 1993-05-06 2006-10-03 Acorda Therapeutics, Inc. Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III
US5912326A (en) 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
US6074841A (en) 1996-08-19 2000-06-13 Millennium Biotherapeutics, Inc. Don-1 gene and polypeptides and uses therefor
AUPQ369599A0 (en) * 1999-10-27 1999-11-18 Griffith University A method of preparing olfactory cells for transplantation
AT516304T (en) 2000-05-23 2011-07-15 Cenes Pharmaceuticals Inc Nrg-2 nucleic acids, polypeptides, and diagnostic / therapeutic methods
US20050053606A1 (en) * 2000-09-11 2005-03-10 KUFE Donald W. MUC1 extracellular domain and cancer treatment compositions and methods derived therefrom
WO2007028085A2 (en) 2005-09-02 2007-03-08 Morehouse School Of Medicine Neuregulin for prevention and treatment of damage from acute assault on vascular and neuronal tissues

Also Published As

Publication number Publication date
BR0111125A (en) 2004-12-28
US20050261186A1 (en) 2005-11-24
US20020081286A1 (en) 2002-06-27
EP2357004B1 (en) 2016-10-12
EP2357004A1 (en) 2011-08-17
ES2370875T3 (en) 2011-12-23
JP2004507224A (en) 2004-03-11
US8114838B2 (en) 2012-02-14
IL153052D0 (en) 2003-06-24
JP6444332B2 (en) 2018-12-26
EP1289553B1 (en) 2011-07-13
AU7494701A (en) 2001-12-03
CA2808215A1 (en) 2001-11-29
US20150274795A1 (en) 2015-10-01
US20120214737A1 (en) 2012-08-23
JP6116536B2 (en) 2017-04-19
MXPA02011656A (en) 2004-07-30
JP5727983B2 (en) 2015-06-03
JP2016146843A (en) 2016-08-18
CA2409996C (en) 2016-03-01
ES2610353T3 (en) 2017-04-27
CA2409996A1 (en) 2001-11-29
US10065999B2 (en) 2018-09-04
US6890751B2 (en) 2005-05-10
JP2019004894A (en) 2019-01-17
JP2015051007A (en) 2015-03-19
WO2001089568A1 (en) 2001-11-29
IL203493A (en) 2014-06-30
ZA200210085B (en) 2004-01-26
JP5324732B2 (en) 2013-10-23
WO2001089568A9 (en) 2002-12-12
EP1289553A1 (en) 2003-03-12
JP2013063069A (en) 2013-04-11
AU2001274947B2 (en) 2006-08-17
EP1289553A4 (en) 2005-06-08
US20190169248A1 (en) 2019-06-06

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