AT51522T - Formulation of non-irritating ophthalmic aqueous compositions for ocular therapeutic agents. - Google Patents

Formulation of non-irritating ophthalmic aqueous compositions for ocular therapeutic agents.

Info

Publication number
AT51522T
AT51522T AT83305184T AT83305184T AT51522T AT 51522 T AT51522 T AT 51522T AT 83305184 T AT83305184 T AT 83305184T AT 83305184 T AT83305184 T AT 83305184T AT 51522 T AT51522 T AT 51522T
Authority
AT
Austria
Prior art keywords
formulation
therapeutic agents
aqueous compositions
ophthalmic aqueous
ocular therapeutic
Prior art date
Application number
AT83305184T
Other languages
German (de)
Inventor
Wesley Wehsin Han
Robert Eugene Roehrs
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US06/415,758 priority Critical patent/US4559343A/en
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Priority to EP83305184A priority patent/EP0105635B1/en
Publication of AT51522T publication Critical patent/AT51522T/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/912Ophthalmic
    • Y10S514/914Inflammation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/974Containing designated ingredient to reduce noxious effects of active ingredient, e.g. taste masking, odor reducing
AT83305184T 1982-09-07 1983-09-06 Formulation of non-irritating ophthalmic aqueous compositions for ocular therapeutic agents. AT51522T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US06/415,758 US4559343A (en) 1982-09-07 1982-09-07 Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents
EP83305184A EP0105635B1 (en) 1982-09-07 1983-09-06 Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therepeutic agents

Publications (1)

Publication Number Publication Date
AT51522T true AT51522T (en) 1990-04-15

Family

ID=23647073

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83305184T AT51522T (en) 1982-09-07 1983-09-06 Formulation of non-irritating ophthalmic aqueous compositions for ocular therapeutic agents.

Country Status (6)

Country Link
US (1) US4559343A (en)
EP (1) EP0105635B1 (en)
JP (1) JPH0551568B2 (en)
AT (1) AT51522T (en)
CA (1) CA1217144A (en)
DE (1) DE3381396D1 (en)

Families Citing this family (44)

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US4567183A (en) * 1983-03-11 1986-01-28 Analgesic Associates Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4682284A (en) * 1984-12-06 1987-07-21 American Telephone & Telegraph Co., At&T Bell Lab. Queue administration method and apparatus
US4728509A (en) * 1985-08-19 1988-03-01 Takeda Chemical Industries, Ltd. Aqueous liquid preparation
DK623586A (en) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperide ingredients or salts thereof and pharmaceutical compositions containing the compounds
US4753945A (en) * 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
US5171566A (en) * 1986-05-16 1992-12-15 The Green Cross Corporation Flurbiprofen derivative ophthalmic preparation
US4778810A (en) * 1987-01-08 1988-10-18 Nastech Pharmaceutical Co., Inc. Nasal delivery of caffeine
JP2764261B2 (en) * 1987-03-17 1998-06-11 リ−ドケミカル株式会社 External anti-inflammatory analgesic
US5110493A (en) * 1987-09-11 1992-05-05 Syntex (U.S.A.) Inc. Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
US4996209A (en) * 1988-06-20 1991-02-26 Alcon Laboratories, Inc. Ophthalmic antiinflammatory compositions comprising S(+)-flurbiprofen
ES2012532A6 (en) * 1988-07-15 1990-04-01 Cusi Lab Ophthalmic aqueous solutions containing lysine- alpha -methyl-4-(2'-thionylcarbonyl) phenyl acetate
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
US5271939A (en) * 1988-10-03 1993-12-21 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5124392A (en) * 1988-10-03 1992-06-23 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US4939135A (en) * 1988-10-03 1990-07-03 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5360611A (en) * 1988-10-03 1994-11-01 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following ultraviolet laser irradiation
US5051443A (en) * 1988-10-12 1991-09-24 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5032575A (en) * 1988-10-12 1991-07-16 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5036046A (en) * 1988-10-12 1991-07-30 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5013751A (en) * 1989-01-10 1991-05-07 Alcon Laboratories, Inc. (+) Suprofen esters and amides as opthalmic anti-inflammatory agents
US4988728A (en) * 1989-11-03 1991-01-29 Alcon Laboratories, Inc. Suprofen esters and amides as ophthalmic anti-inflammatory agents
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5444076A (en) * 1990-11-26 1995-08-22 Roemmers S.A.I.C.F. Pharmaceutical preparation for topical application
DE4037554A1 (en) * 1990-11-26 1992-05-27 Roemmers Sa Medicament for topical application
US5281353A (en) * 1991-04-24 1994-01-25 Allergan, Inc. Compositions and methods for disinfecting/cleaning of lenses and for destroying oxidative disinfectants
NZ242358A (en) * 1991-05-10 1994-03-25 Allergan Inc Use of thiol compounds to inhibit deposits on a contact lens
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
US5624893A (en) * 1993-10-14 1997-04-29 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
CN1129400A (en) * 1994-05-06 1996-08-21 阿尔康实验室公司 Use of vitamin E. Tocopheryl derivatives in ophthalmic compositions
US6309630B1 (en) 1994-05-24 2001-10-30 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic suspensions
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
GB9613457D0 (en) * 1996-06-27 1996-08-28 Procter & Gamble Pharmaceutical compositions
US5814655A (en) * 1996-11-14 1998-09-29 Insite Vision Incorporated Non-steroidal ophthalmic mixtures
US6274592B1 (en) * 1997-02-04 2001-08-14 Senju Pharmaceutical Co., Ltd. Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
US6265444B1 (en) 1997-05-23 2001-07-24 Insite Vision Incorporated Ophthalmic composition
PE20020578A1 (en) 2000-10-10 2002-08-14 Upjohn Co A topical antibiotic composition for treating eye infections
US20030220376A1 (en) * 2001-08-10 2003-11-27 Pharmacia Corporation Methods for treating carbonic anhydrase mediated disorders
US20040034042A1 (en) * 2002-08-14 2004-02-19 Masao Tsuji Preservative composition
CA2477049A1 (en) * 2002-02-22 2003-09-04 Syed Hassan Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride
US20030191187A1 (en) * 2002-04-01 2003-10-09 Lee Fang Yu Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same
WO2005102303A2 (en) * 2004-04-21 2005-11-03 Advanced Ocular Systems Limited Antiprostaglandins for the treatment of ocular pathologies
US20090092574A1 (en) 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
EA201391043A1 (en) 2011-02-17 2014-03-31 Сентисс Фарма Прайвет Лимитед Method and composition for slowing the sorption of preservants by plastics

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2994640A (en) * 1957-02-22 1961-08-01 Byk Gulden Lomberg Chem Fab Anti-inflammatory therapy with purine molecular compounds
US3439094A (en) * 1967-07-20 1969-04-15 Warner Lambert Pharmaceutical Analgesic compositions containing namol xenyrate,caffeine and acetyl-rho-aminophenol
DE1911279A1 (en) * 1969-03-05 1970-11-12 Eckert Dr Theodor Method for increasing the absorbability of drugs
US4141976A (en) * 1976-01-05 1979-02-27 The Regents Of The University Of Michigan Process for alleviating proliferative skin diseases
US3957994A (en) * 1974-12-19 1976-05-18 Nelson Research & Development Company Topical anti-inflammatory composition and method of use
NL7707501A (en) * 1976-08-12 1978-02-14 Knoll Ag Externally administrable pharmaceutical preparation.
JPS648602B2 (en) * 1979-12-28 1989-02-14 Kaken Pharma Co Ltd
JPH0141608B2 (en) * 1980-04-30 1989-09-06 Kaken Pharma Co Ltd
DE3390116C2 (en) * 1982-07-22 1994-06-16 Richardson Vicks Inc Improved caffeine-containing analgesic and anti-inflammatory agents
US4420483A (en) * 1982-07-22 1983-12-13 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same

Also Published As

Publication number Publication date
JPH0551568B2 (en) 1993-08-03
CA1217144A1 (en)
EP0105635A3 (en) 1986-06-11
JPS5973520A (en) 1984-04-25
CA1217144A (en) 1987-01-27
EP0105635A2 (en) 1984-04-18
EP0105635B1 (en) 1990-04-04
US4559343A (en) 1985-12-17
DE3381396D1 (en) 1990-05-10

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee