AT513832T - 8-anilinoimidazopyridines and their use as anticrobraids and / or anti-inflammatory agents - Google Patents

8-anilinoimidazopyridines and their use as anticrobraids and / or anti-inflammatory agents

Info

Publication number
AT513832T
AT513832T AT08868471T AT08868471T AT513832T AT 513832 T AT513832 T AT 513832T AT 08868471 T AT08868471 T AT 08868471T AT 08868471 T AT08868471 T AT 08868471T AT 513832 T AT513832 T AT 513832T
Authority
AT
Austria
Prior art keywords
anticrobraids
anilinoimidazopyridines
anti
use
inflammatory agents
Prior art date
Application number
AT08868471T
Other languages
German (de)
Inventor
Stephen Price
Robert Heald
Pascal Pierre Alexandre Savy
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US1515507P priority Critical
Priority to US5402408P priority
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to PCT/US2008/087476 priority patent/WO2009085980A1/en
Publication of AT513832T publication Critical patent/AT513832T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
AT08868471T 2007-12-19 2008-12-18 8-anilinoimidazopyridines and their use as anticrobraids and / or anti-inflammatory agents AT513832T (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US1515507P true 2007-12-19 2007-12-19
US5402408P true 2008-05-16 2008-05-16
PCT/US2008/087476 WO2009085980A1 (en) 2007-12-19 2008-12-18 8-anilin0imidaz0pyridines and their use as anti-cancer and/or anti-inflammatory agents

Publications (1)

Publication Number Publication Date
AT513832T true AT513832T (en) 2011-07-15

Family

ID=40404998

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08868471T AT513832T (en) 2007-12-19 2008-12-18 8-anilinoimidazopyridines and their use as anticrobraids and / or anti-inflammatory agents

Country Status (16)

Country Link
US (1) US8293763B2 (en)
EP (1) EP2231662B1 (en)
JP (1) JP5710268B2 (en)
KR (1) KR20100101666A (en)
CN (1) CN101903387B (en)
AT (1) AT513832T (en)
AU (1) AU2008343062B2 (en)
CA (1) CA2704125A1 (en)
DK (1) DK2231662T3 (en)
IL (1) IL205490A (en)
NZ (1) NZ585306A (en)
PL (1) PL2231662T3 (en)
PT (1) PT2231662E (en)
RU (1) RU2498985C2 (en)
WO (1) WO2009085980A1 (en)
ZA (1) ZA201003046B (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009085983A1 (en) * 2007-12-19 2009-07-09 Genentech, Inc. 5-anilinoimidazopyridines and methods of use
AU2010276537B2 (en) 2009-07-27 2015-04-16 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
CA2802288C (en) 2010-07-02 2018-08-21 Gilead Sciences, Inc. Triazolopyridinone compounds as ion channel modulators
ES2648820T3 (en) 2011-05-10 2018-01-08 Gilead Sciences, Inc. Condensed heterocyclic compounds as modulators of sodium channels
TW201837023A (en) 2011-07-01 2018-10-16 美商基利科學股份有限公司 Fused heterocyclic compounds as ion channel modulators
NO3175985T3 (en) 2011-07-01 2018-04-28
SG11201400666PA (en) 2011-09-14 2014-09-26 Samumed Llc Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors
SG10201610539RA (en) 2012-04-04 2017-02-27 Samumed Llc Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
KR101223245B1 (en) * 2012-09-12 2013-01-17 삼부기술 주식회사 Map image making system
US9532987B2 (en) 2013-09-05 2017-01-03 Genentech, Inc. Use of a combination of a MEK inhibitor and an ERK inhibitor for treatment of hyperproliferative diseases
WO2015057823A1 (en) 2013-10-15 2015-04-23 Radux Devices, LLC Securing a medical device to a valve instrument
TWI664164B (en) 2014-02-13 2019-07-01 美商英塞特控股公司 Cyclopropylamines as lsd1 inhibitors
US9493442B2 (en) 2014-02-13 2016-11-15 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
US9670210B2 (en) 2014-02-13 2017-06-06 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
WO2015123437A1 (en) 2014-02-13 2015-08-20 Incyte Corporation Cyclopropylamines as lsd1 inhibitors
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
WO2016007731A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Imidazopyridines and imidazopyrazines as lsd1 inhibitors
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
WO2016007727A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
CN105315293A (en) * 2014-07-29 2016-02-10 上海科州药物研发有限公司 Heterocyclic compounds serving as protein kinase inhibitors and preparation method for heterocyclic compounds and use of heterocyclic compounds
WO2016040185A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
WO2016040180A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
EP3277689B1 (en) 2015-04-03 2019-09-04 Incyte Corporation Heterocyclic compounds as lsd1 inhibitors
GB201511790D0 (en) * 2015-07-06 2015-08-19 Iomet Pharma Ltd Pharmaceutical compound
WO2017023975A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
WO2017023984A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
US10392383B2 (en) 2015-08-03 2019-08-27 Samumed, Llc 3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
WO2017024010A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
WO2017023987A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
WO2017023996A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
WO2017023980A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
WO2017023993A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-indol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
WO2017024004A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10519169B2 (en) 2015-08-03 2019-12-31 Samumed, Llc 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
WO2017023972A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10329309B2 (en) 2015-08-03 2019-06-25 Samumed, Llc 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
US10231956B2 (en) 2015-08-03 2019-03-19 Samumed, Llc 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
WO2017024021A1 (en) 2015-08-03 2017-02-09 Samumed, Llc 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
AU2016306555A1 (en) 2015-08-12 2018-03-15 Incyte Corporation Salts of an LSD1 inhibitor
WO2017079765A1 (en) * 2015-11-06 2017-05-11 Samumed, Llc Treatment of osteoarthritis
CN109072311A (en) 2016-04-15 2018-12-21 豪夫迈·罗氏有限公司 Diagnostic and therapeutic method for cancer
KR20190018628A (en) 2016-04-22 2019-02-25 인사이트 코포레이션 Formulation of LSD1 inhibitor
TW201919707A (en) 2017-09-08 2019-06-01 美商建南德克公司 Diagnostic and therapeutic methods for cancer
WO2019158579A1 (en) 2018-02-13 2019-08-22 Vib Vzw Targeting minimal residual disease in cancer with rxr antagonists

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6068600A (en) 1999-07-16 2001-02-05 Warner-Lambert Company Method for treating chronic pain using mek inhibitors
AU7349801A (en) 2000-07-19 2002-01-30 Warner Lambert Co Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids
JP4206273B2 (en) * 2001-04-27 2009-01-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 Pyrazolo [1,5-a] pyridine compounds and pharmaceuticals thereof
DOP2003000614A (en) 2002-03-13 2009-09-30 Array Biopharma Inc N3 alkylated benzimidazole derivatives as mek inhibitors (n3 alkylated benzimidazole
EP2130537B1 (en) 2002-03-13 2012-11-14 Array Biopharma, Inc. N3 alkylated benzimidazole derivatives as mek inhibitors
JP3764440B2 (en) * 2002-05-24 2006-04-05 日東電工株式会社 Manufacturing method of optical film
GB0226724D0 (en) * 2002-11-15 2002-12-24 Merck Sharp & Dohme Therapeutic agents
SE0301373D0 (en) * 2003-05-09 2003-05-09 Astrazeneca Ab Novel compounds
US7538120B2 (en) * 2003-09-03 2009-05-26 Array Biopharma Inc. Method of treating inflammatory diseases
US7144907B2 (en) * 2003-09-03 2006-12-05 Array Biopharma Inc. Heterocyclic inhibitors of MEK and methods of use thereof
WO2005051906A2 (en) * 2003-11-19 2005-06-09 Array Biopharma Inc. Heterocyclic inhibitors of mek and methods of use thereof
MY145634A (en) * 2003-12-29 2012-03-15 Squibb Bristol Myers Co Pyrrolotriazine compounds as kinase inhibitors
DE602005016718D1 (en) * 2004-12-01 2009-10-29 Merck Serono Sa Coinsins Ä1,2,4ütriazoloä4,3-aüpyridin derivative for the treatment of hyperproliferative diseases

Also Published As

Publication number Publication date
CA2704125A1 (en) 2009-07-09
CN101903387A (en) 2010-12-01
US20100280063A1 (en) 2010-11-04
NZ585306A (en) 2012-05-25
KR20100101666A (en) 2010-09-17
EP2231662B1 (en) 2011-06-22
AU2008343062B2 (en) 2013-03-07
JP5710268B2 (en) 2015-04-30
DK2231662T3 (en) 2011-08-29
CN101903387B (en) 2014-05-21
WO2009085980A1 (en) 2009-07-09
IL205490D0 (en) 2010-12-30
RU2498985C2 (en) 2013-11-20
RU2010129910A (en) 2012-01-27
ZA201003046B (en) 2011-08-31
JP2011507888A (en) 2011-03-10
PT2231662E (en) 2011-09-12
IL205490A (en) 2015-09-24
PL2231662T3 (en) 2011-11-30
AU2008343062A1 (en) 2009-07-09
US8293763B2 (en) 2012-10-23
EP2231662A1 (en) 2010-09-29

Similar Documents

Publication Publication Date Title
FR2911249B1 (en) Foaming composition for killing arthropods and use thereof
DK1954140T3 (en) Glycerollevulinetketals and their use
FR2904549B1 (en) Composition comprising sarsasapogenin
DK2332914T3 (en) Substituted 4-aminopicolinic acids and their use as herbicides
DK2158313T3 (en) Fungal peroxygenases and methods for their use
GB0719803D0 (en) Therapeutic compounds and their use
AT489465T (en) Targeted integration in the ppp1r12c position
IL211147D0 (en) 1h-benzimidazole-5-carboxamides as anti-inflammatory agents
IL212400A (en) Spiro-oxindole compounds and their use as therapeutic agents
PL1808457T3 (en) Dialkylterephthalates and their use as plasticizers
BRPI0818946A2 (en) "absorbent article"
DK2570467T3 (en) Compositions of the tetrafluorpropene and carbon hydrodes
DK2222675T3 (en) 5-anilinoimidazopyridines and procedures for their use
RU2016133168A (en) Isoxasoline compositions and their application as anti-parasitic agents
BRPI0907231A2 (en) pyrrolpyrimidines and pyrrolpyridines
DE602007010795D1 (en) Leaves and hatchers
HK1183435A1 (en) Frizzled-binding agents and uses thereof
BRPI0811871A2 (en) Bioactive acid agrochemical compositions and use of the same
LT2318366T (en) Psma-binding agents and uses thereof
DK2234985T3 (en) 4- (4-cyano-2-thioaryl) dihydropyrimidinones and their use
AT528300T (en) Bicyclic compounds and their use as antidiabetika
GB0701426D0 (en) Compounds and their use
BRPI1012533A2 (en) pyradazinone compound and use thereof
AT540329T (en) Endoskopobjektivlinse and endoscope
AT446151T (en) Stanzniet and matrize

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2231662

Country of ref document: EP