AT452910T - E-selectin / l-selectin-liganden polypeptides of hematopoetic cells and method for their use - Google Patents

E-selectin / l-selectin-liganden polypeptides of hematopoetic cells and method for their use

Info

Publication number
AT452910T
AT452910T AT01988458T AT01988458T AT452910T AT 452910 T AT452910 T AT 452910T AT 01988458 T AT01988458 T AT 01988458T AT 01988458 T AT01988458 T AT 01988458T AT 452910 T AT452910 T AT 452910T
Authority
AT
Austria
Prior art keywords
selectin
liganden
polypeptides
use
method
Prior art date
Application number
AT01988458T
Other languages
German (de)
Inventor
Robert Sackstein
Original Assignee
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US24098700P priority Critical
Priority to US29747401P priority
Application filed by Brigham & Womens Hospital filed Critical Brigham & Womens Hospital
Priority to PCT/US2001/051014 priority patent/WO2002044342A2/en
Publication of AT452910T publication Critical patent/AT452910T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70585CD44
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/59Lectins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/599Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • C12N2501/72Transferases (EC 2.)
    • C12N2501/724Glycosyltransferases (EC 2.4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/90Polysaccharides
AT01988458T 2000-10-18 2001-10-18 E-selectin / l-selectin-liganden polypeptides of hematopoetic cells and method for their use AT452910T (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US24098700P true 2000-10-18 2000-10-18
US29747401P true 2001-06-11 2001-06-11
PCT/US2001/051014 WO2002044342A2 (en) 2000-10-18 2001-10-18 Hematopoietic cell e-selection/l-selectin ligand polypeptides and methods of use thereof

Publications (1)

Publication Number Publication Date
AT452910T true AT452910T (en) 2010-01-15

Family

ID=26933888

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01988458T AT452910T (en) 2000-10-18 2001-10-18 E-selectin / l-selectin-liganden polypeptides of hematopoetic cells and method for their use

Country Status (9)

Country Link
US (4) US7875585B2 (en)
EP (3) EP3106467B1 (en)
JP (1) JP4198990B2 (en)
AT (1) AT452910T (en)
CA (1) CA2429625C (en)
DE (1) DE60140903D1 (en)
DK (1) DK2174954T3 (en)
ES (2) ES2576678T3 (en)
WO (1) WO2002044342A2 (en)

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US20060003924A1 (en) * 1994-10-11 2006-01-05 Robert Sackstein Sulfation-independent L-selectin or E-selectin ligand (HCELL) and therapeutics thereof
US20060210558A1 (en) * 2000-10-18 2006-09-21 Robert Sackstein Hematopoietic cell selectin ligand polypeptides and methods of use thereof
EP3106467B1 (en) 2000-10-18 2019-04-10 Robert Sackstein Hematopoietic cell e-selectin / l-selectin ligand polypeptides and methods of use thereof
US7332334B2 (en) * 2003-04-18 2008-02-19 Oklahoma Medical Research Foundation Hematopoietic stem cells treated by in vitro fucosylation and methods of use
WO2005046597A2 (en) * 2003-11-07 2005-05-26 Brigham And Womens's Hospital, Inc. Antibodies to cd44 glycoforms and uses thereof
WO2006068720A2 (en) * 2004-11-12 2006-06-29 The Brigham And Women's Hospital, Inc. Hematopoietic cell selectin ligand polypeptides and methods of use thereof
WO2006104609A2 (en) * 2005-02-24 2006-10-05 The Scripps Research Institute Isolated myeloid-like bone marrow cell populations and methods of treatment therewith
US8034613B2 (en) * 2005-06-01 2011-10-11 Wisconsin Alumni Research Foundation Multipotent lymphohematopoietic progenitor cells
KR101489728B1 (en) * 2005-06-24 2015-02-04 데저트 레이크 테크놀로지스 Purified component of blue-green algae and method of use
FI20055398A0 (en) 2005-07-08 2005-07-08 Suomen Punainen Risti Veripalv Method for evaluating cell populations
US8084236B2 (en) * 2006-06-02 2011-12-27 Robert Sackstein Compositions and methods for modifying cell surface glycans
WO2008011094A2 (en) * 2006-07-18 2008-01-24 Robert Sackstein Cytokine induction of selectin ligands on cells
KR101054362B1 (en) 2008-07-03 2011-08-05 재단법인 목암생명공학연구소 How to reduce the fucose content of recombinant protein
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
EP2403518A4 (en) * 2009-03-06 2013-01-23 Angstrom Pharmaceuticals Inc Compositions and methods for modulation of cell migration
WO2011149525A1 (en) 2010-05-25 2011-12-01 Arryx, Inc. Holographic fluctuation microscopy apparatus and method for determining mobility of particle and/or cell dispersions
KR101026999B1 (en) 2010-12-08 2011-04-11 재단법인 목암생명공학연구소 How to reduce the fucose content of recombinant protein
US9788539B2 (en) 2011-05-17 2017-10-17 Velico Medical, Inc. Platelet protection solution having beta-galactosidase and sialidase inhibitors
WO2014055988A1 (en) 2012-10-05 2014-04-10 Velico Medical, Inc. Platelet additive solution having a beta-galactosidase inhibitor
SG11201705401YA (en) 2014-12-30 2017-08-30 The Brigham And Women`S Hospital Inc Methods to improve cell therapy
CN104730231B (en) * 2015-03-26 2016-06-08 北京乐普医疗科技有限责任公司 A kind of sample buffer for fluorescence immunoassay detection by quantitative and application thereof

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EP3106467B1 (en) * 2000-10-18 2019-04-10 Robert Sackstein Hematopoietic cell e-selectin / l-selectin ligand polypeptides and methods of use thereof
US8084236B2 (en) * 2006-06-02 2011-12-27 Robert Sackstein Compositions and methods for modifying cell surface glycans
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Also Published As

Publication number Publication date
US10370642B2 (en) 2019-08-06
DK2174954T3 (en) 2016-07-04
US9523078B2 (en) 2016-12-20
CA2429625C (en) 2012-05-01
ES2576678T3 (en) 2016-07-08
JP2004527468A (en) 2004-09-09
US20030040607A1 (en) 2003-02-27
US20110189139A1 (en) 2011-08-04
CA2429625A1 (en) 2002-06-06
WO2002044342A2 (en) 2002-06-06
EP3106467B1 (en) 2019-04-10
WO2002044342A3 (en) 2004-03-25
US20130089927A1 (en) 2013-04-11
EP2174954A1 (en) 2010-04-14
WO2002044342A9 (en) 2003-06-19
JP4198990B2 (en) 2008-12-17
EP1421174A4 (en) 2004-09-22
EP2174954B1 (en) 2016-03-23
ES2338757T3 (en) 2010-05-12
EP1421174B1 (en) 2009-12-23
US7875585B2 (en) 2011-01-25
EP1421174A2 (en) 2004-05-26
US20160201033A1 (en) 2016-07-14
DE60140903D1 (en) 2010-02-04
EP3106467A1 (en) 2016-12-21

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