AT426398T - Process for preparing a dexamethasone-containing formulation for oral use - Google Patents

Process for preparing a dexamethasone-containing formulation for oral use

Info

Publication number
AT426398T
AT426398T AT04712644T AT04712644T AT426398T AT 426398 T AT426398 T AT 426398T AT 04712644 T AT04712644 T AT 04712644T AT 04712644 T AT04712644 T AT 04712644T AT 426398 T AT426398 T AT 426398T
Authority
AT
Austria
Prior art keywords
dexamethasone
preparing
process
oral use
containing formulation
Prior art date
Application number
AT04712644T
Other languages
German (de)
Inventor
Paul Rice
Nicholas Mchardy
Original Assignee
Constant Res & Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US44817403P priority Critical
Application filed by Constant Res & Dev Ltd filed Critical Constant Res & Dev Ltd
Publication of AT426398T publication Critical patent/AT426398T/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
AT04712644T 2003-02-20 2004-02-19 Process for preparing a dexamethasone-containing formulation for oral use AT426398T (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US44817403P true 2003-02-20 2003-02-20

Publications (1)

Publication Number Publication Date
AT426398T true AT426398T (en) 2009-04-15

Family

ID=32908546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04712644T AT426398T (en) 2003-02-20 2004-02-19 Process for preparing a dexamethasone-containing formulation for oral use

Country Status (5)

Country Link
US (1) US20060034915A1 (en)
EP (1) EP1594471B1 (en)
AT (1) AT426398T (en)
DE (1) DE602004020187D1 (en)
WO (1) WO2004073685A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101741B2 (en) 2005-11-02 2012-01-24 Protiva Biotherapeutics, Inc. Modified siRNA molecules and uses thereof
US7915399B2 (en) 2006-06-09 2011-03-29 Protiva Biotherapeutics, Inc. Modified siRNA molecules and uses thereof
GB2455539B (en) * 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
CN105997866B (en) * 2016-07-13 2019-08-20 成都明慈医药科技有限公司 A kind of suspension and preparation method thereof containing dexamethasone

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2946298A (en) * 1957-11-13 1960-07-26 Arthur Colton Company Compression coating tablet press
NL125158C (en) * 1959-10-01
GB970440A (en) * 1961-08-14 1964-09-23 Merck & Co Inc Anti-inflammatory compositions comprising steroids and indole derivatives
US3231468A (en) * 1962-07-02 1966-01-25 Merck & Co Inc Dexamethasone-cyproheptadine oral antiflammatory compositions
JPS6121526B2 (en) * 1980-09-30 1986-05-27 Takeda Chemical Industries Ltd
DE3690101C2 (en) * 1985-03-01 1995-06-08 Freunt Ind Co Ltd Process and apparatus for coating fluidised grains by spraying
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
AU739031B2 (en) * 1996-11-15 2001-10-04 Procter & Gamble Company, The Pharmaceutical dosage form for colonic delivery
AT247984T (en) * 1997-02-11 2003-09-15 Univ Manchester Bioreductive conjugates for targeted active substance
IT1303692B1 (en) * 1998-11-03 2001-02-23 Chiesi Farma Spa Process for the preparation of suspensions of particles difarmaci to be administered by inhalation.

Also Published As

Publication number Publication date
EP1594471A1 (en) 2005-11-16
WO2004073685A1 (en) 2004-09-02
EP1594471B1 (en) 2009-03-25
US20060034915A1 (en) 2006-02-16
DE602004020187D1 (en) 2009-05-07

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties