US20030143647A1
(en)
|
2001-09-24 |
2003-07-31 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Anticancer vaccine and diagnostic methods and reagents
|
NZ550810A
(en)
*
|
2004-05-19 |
2009-05-31 |
Immunocore Ltd |
High affinity NY-ESO T cell receptor
|
US20060084607A1
(en)
|
2004-07-06 |
2006-04-20 |
Lisa Spirio |
Purified amphiphilic peptide compositions and uses thereof
|
WO2006036445A2
(en)
|
2004-09-24 |
2006-04-06 |
Trustees Of Dartmouth College |
Chimeric nk receptor and methods for treating cancer
|
WO2007044033A2
(en)
|
2004-12-07 |
2007-04-19 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Therapeutic and diagnostic cloned mhc-unrestricted receptor specific for the muc1 tumor associated antigen
|
SI1699826T1
(en)
|
2005-01-05 |
2009-08-31 |
Ngsges M B H F Star Biotechnol |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
GB0511124D0
(en)
*
|
2005-06-01 |
2005-07-06 |
Avidex Ltd |
High affinity melan-a t cell receptors
|
IN2014DN06624A
(en)
|
2005-10-18 |
2015-07-10 |
Univ Colorado |
|
US20090208502A1
(en)
*
|
2005-12-20 |
2009-08-20 |
Ralph Alexander Willemsen |
Apoptosis-inducing protein complexes and therapeutic use thereof
|
AT503861B1
(en)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
METHOD FOR MANIPULATING T-CELL RECEPTORS
|
WO2008039818A2
(en)
|
2006-09-26 |
2008-04-03 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Modified t cell receptors and related materials and methods
|
WO2008037943A1
(en)
*
|
2006-09-29 |
2008-04-03 |
Medigene Limited |
Cells transformed with nucleic acid encoding ny-eso t cell receptors
|
EP2087000A2
(en)
*
|
2006-09-29 |
2009-08-12 |
Immunocore Ltd. |
T cell therapies
|
US8921279B2
(en)
|
2007-06-26 |
2014-12-30 |
F-Star Biotechnologische Forschungs—und Entwicklungsges. m.b.H |
Display of binding agents
|
US20100297093A1
(en)
*
|
2007-09-25 |
2010-11-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human |
Modified t cell receptors and related materials and methods
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
WO2010011994A2
(en)
|
2008-07-25 |
2010-01-28 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Polypeptides and uses thereof
|
CN104353066B
(en)
|
2008-08-28 |
2017-05-10 |
泰加生物工艺学公司 |
Modulators of MYC, methods of using the same, and methods of identifying agents that modulate MYC
|
GB0816096D0
(en)
*
|
2008-09-04 |
2008-10-15 |
Medigene Ltd |
Diabetes t cell receptors
|
GB0908613D0
(en)
|
2009-05-20 |
2009-06-24 |
Immunocore Ltd |
T Cell Reseptors
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
US9181527B2
(en)
|
2009-10-29 |
2015-11-10 |
The Trustees Of Dartmouth College |
T cell receptor-deficient T cell compositions
|
JP2013535199A
(en)
*
|
2010-07-28 |
2013-09-12 |
イムノコア リミテッド |
T cell receptor
|
US9833476B2
(en)
|
2011-08-31 |
2017-12-05 |
The Trustees Of Dartmouth College |
NKP30 receptor targeted therapeutics
|
WO2013041865A1
(en)
*
|
2011-09-22 |
2013-03-28 |
Immunocore Limited |
T cell receptors
|
EP2760892A1
(en)
|
2011-09-29 |
2014-08-06 |
Apo-T B.V. |
Multi-specific binding molecules targeting aberrant cells
|
US20130183307A1
(en)
|
2012-01-13 |
2013-07-18 |
Johan Renes |
Aberrant cell-restricted immunoglobulins provided with a toxic moiety
|
ES2719495T3
(en)
|
2012-05-07 |
2019-07-10 |
Dartmouth College |
Antibody directed against b7-h6, fusion proteins, and methods of use thereof
|
ES2718474T3
(en)
|
2012-05-22 |
2019-07-02 |
Us Health |
Murine T-cell receptors anti-NY-ESO-1
|
CN104640551A
(en)
|
2012-07-20 |
2015-05-20 |
泰加生物工艺学公司 |
Enhanced reconstitution and autoreconstitution of the hematopoietic compartment
|
CA2880098A1
(en)
|
2012-07-27 |
2014-01-30 |
The Board Of Trustees Of The University Of Illinois |
Engineering t-cell receptors
|
US10272115B2
(en)
|
2013-03-11 |
2019-04-30 |
Taiga Biotechnologies, Inc. |
Production and use of red blood cells
|
DK2971045T3
(en)
|
2013-03-13 |
2019-09-16 |
Health Research Inc |
Compositions and Methods for Using Recombinant T-Cell Receptors for Direct Recognition of Tumor Antigen
|
US9937207B2
(en)
|
2013-03-21 |
2018-04-10 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell receptor genes using talens
|
KR101904385B1
(en)
*
|
2013-06-26 |
2018-10-05 |
광저우 샹쉐 파마스티컬 컴퍼니 리미티드 |
High-stability T-cell Receptor and Preparation Method and Application Thereof
|
CA2930852A1
(en)
|
2013-11-22 |
2015-05-28 |
The Board Of Trustees Of The University Of Illinois |
Engineered high-affinity human t cell receptors
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
KR102290829B1
(en)
*
|
2014-03-14 |
2021-08-18 |
이뮤노코어 리미티드 |
Tcr libraries
|
WO2016014725A1
(en)
|
2014-07-22 |
2016-01-28 |
The University Of Notre Dame Du Lac |
Molecular constructs and uses thereof
|
WO2016054086A1
(en)
*
|
2014-09-30 |
2016-04-07 |
The Regents Of The University Of California |
Codon-optimized lentiviral vector for stem cell reprogramming
|
CA2964953A1
(en)
|
2014-10-31 |
2016-05-06 |
The Trustees Of The University Of Pennsylvania |
Altering gene expression in cart cells and uses thereof
|
EP3234193B1
(en)
|
2014-12-19 |
2020-07-15 |
Massachusetts Institute of Technology |
Molecular biomarkers for cancer immunotherapy
|
EP3234130B1
(en)
|
2014-12-19 |
2020-11-25 |
The Broad Institute, Inc. |
Methods for profiling the t-cell- receptor repertoire
|
BR112017024797A2
(en)
|
2015-05-20 |
2018-08-07 |
The Broad Institute Inc. |
shared neoantigens
|
NL2014935B1
(en)
|
2015-06-08 |
2017-02-03 |
Applied Immune Tech Ltd |
T cell receptor like antibodies having fine specificity.
|
EP3436575A1
(en)
|
2015-06-18 |
2019-02-06 |
The Broad Institute Inc. |
Novel crispr enzymes and systems
|
WO2017023801A1
(en)
|
2015-07-31 |
2017-02-09 |
Regents Of The University Of Minnesota |
Intracellular genomic transplant and methods of therapy
|
GB201516272D0
(en)
*
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
US20190255107A1
(en)
|
2015-10-09 |
2019-08-22 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
WO2017075478A2
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
AU2016355178B9
(en)
|
2015-11-19 |
2019-05-30 |
Massachusetts Institute Of Technology |
Lymphocyte antigen CD5-like (CD5L)-interleukin 12B (p40) heterodimers in immunity
|
GB201522592D0
(en)
*
|
2015-12-22 |
2016-02-03 |
Immunocore Ltd |
T cell receptors
|
AU2017254477A1
(en)
|
2016-04-18 |
2018-11-01 |
Jennifer G. ABELIN |
Improved HLA epitope prediction
|
WO2018035364A1
(en)
|
2016-08-17 |
2018-02-22 |
The Broad Institute Inc. |
Product and methods useful for modulating and evaluating immune responses
|
US20190262399A1
(en)
|
2016-09-07 |
2019-08-29 |
The Broad Institute, Inc. |
Compositions and methods for evaluating and modulating immune responses
|
EP3512875A2
(en)
|
2016-09-15 |
2019-07-24 |
Quadrucept Bio Limited |
Multimers, tetramers&octamers
|
US20200016202A1
(en)
|
2016-10-07 |
2020-01-16 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
JP2019532080A
(en)
|
2016-10-18 |
2019-11-07 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
Tumor infiltrating lymphocytes and methods of treatment
|
TW201831690A
(en)
|
2016-10-31 |
2018-09-01 |
美商艾歐凡斯生物治療公司 |
Engineered artificial antigen presenting cells for tumor infiltrating lymphocyte expansion
|
CN108117596A
(en)
*
|
2016-11-29 |
2018-06-05 |
广东香雪精准医疗技术有限公司 |
For the high-affinity TCR of NY-ESO
|
CN113786476A
(en)
|
2016-12-02 |
2021-12-14 |
泰加生物工艺学公司 |
Nanoparticle formulations
|
WO2018129336A1
(en)
|
2017-01-06 |
2018-07-12 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
|
KR20190104048A
(en)
|
2017-01-06 |
2019-09-05 |
이오반스 바이오테라퓨틱스, 인크. |
Expansion of Tumor Infiltrating Lymphocytes (TIL) with Tumor Necrosis Factor Receptor Superfamily (TNFRSF) Agonists and Treatment Combinations of TILs and TNFRSF Agonists
|
BR112019014510A2
(en)
*
|
2017-01-13 |
2020-02-18 |
Agenus Inc. |
T-CELL RECEPTORS THAT CONNECT TO NY-ESO-1 AND METHODS OF USING THEM
|
US20200096521A1
(en)
|
2017-02-12 |
2020-03-26 |
Neon Therapeutics, Inc. |
Hla-based methods and compositions and uses thereof
|
BR112019018915A2
(en)
|
2017-03-15 |
2020-04-14 |
Pandion Therapeutics Inc |
targeted immunotolerance
|
US20210293783A1
(en)
|
2017-04-18 |
2021-09-23 |
The General Hospital Corporation |
Compositions for detecting secretion and methods of use
|
EP3714041A1
(en)
|
2017-11-22 |
2020-09-30 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
BR112019024127A2
(en)
|
2017-05-24 |
2020-06-23 |
Pandion Therapeutics, Inc. |
TARGETED IMMUNOTOLERANCE
|
WO2019006418A2
(en)
|
2017-06-30 |
2019-01-03 |
Intima Bioscience, Inc. |
Adeno-associated viral vectors for gene therapy
|
EP4026554A1
(en)
|
2017-08-03 |
2022-07-13 |
Taiga Biotechnologies, Inc. |
Methods and compositions for the treatment of melanoma
|
US10149898B2
(en)
|
2017-08-03 |
2018-12-11 |
Taiga Biotechnologies, Inc. |
Methods and compositions for the treatment of melanoma
|
CA3073848A1
(en)
|
2017-09-21 |
2019-03-28 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
WO2019057122A1
(en)
*
|
2017-09-22 |
2019-03-28 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Novel bispecific polypeptide complexes
|
JP2020534035A
(en)
|
2017-09-22 |
2020-11-26 |
ウーシー バイオロジクス アイルランド リミティド |
New bispecific CD3 / CD19 polypeptide complex cross-reference
|
KR20200063215A
(en)
|
2017-10-06 |
2020-06-04 |
오슬로 유니버시테시케후스 에이치에프 |
Chimeric antigen receptor
|
WO2019084427A1
(en)
*
|
2017-10-27 |
2019-05-02 |
Kite Pharma, Inc. |
T cell receptor antigen binding molecules and methods of use thereof
|
CN109837245A
(en)
*
|
2017-11-25 |
2019-06-04 |
深圳宾德生物技术有限公司 |
A kind of T cell receptor gene modification T cell and its preparation method and application for the targeting NY-ESO-1 that TCR is knocked out
|
US10946068B2
(en)
|
2017-12-06 |
2021-03-16 |
Pandion Operations, Inc. |
IL-2 muteins and uses thereof
|
US10174092B1
(en)
|
2017-12-06 |
2019-01-08 |
Pandion Therapeutics, Inc. |
IL-2 muteins
|
CA3085765A1
(en)
|
2017-12-15 |
2019-06-20 |
Iovance Biotherapeutics, Inc. |
Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof
|
JP7068459B2
(en)
*
|
2018-02-26 |
2022-05-16 |
メディジーン イミュノテラピーズ ゲーエムベーハー |
NYESO TCR
|
WO2019175209A1
(en)
|
2018-03-14 |
2019-09-19 |
Medigene Immunotherapies Gmbh |
Inducible t cell receptors and uses thereof
|
WO2019232542A2
(en)
|
2018-06-01 |
2019-12-05 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
EP3833443A1
(en)
|
2018-08-09 |
2021-06-16 |
Compass Therapeutics LLC |
Antigen binding agents that bind cd277 and uses thereof
|
US20210177832A1
(en)
|
2018-08-20 |
2021-06-17 |
The Broad Institute, Inc. |
Inhibitors of rna-guided nuclease target binding and uses thereof
|
WO2020041384A1
(en)
|
2018-08-20 |
2020-02-27 |
The Broad Institute, Inc. |
3-phenyl-2-cyano-azetidine derivatives, inhibitors of rna-guided nuclease activity
|
WO2020041387A1
(en)
|
2018-08-20 |
2020-02-27 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
JP2022500022A
(en)
|
2018-09-05 |
2022-01-04 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
T cell modification
|
US20210382068A1
(en)
|
2018-10-02 |
2021-12-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
US20210379057A1
(en)
|
2018-10-16 |
2021-12-09 |
Massachusetts Institute Of Technology |
Nutlin-3a for use in treating a mycobacterium tuberculosis infection
|
EP3870602A1
(en)
|
2018-10-23 |
2021-09-01 |
Regeneron Pharmaceuticals, Inc. |
Ny-eso-1 t cell receptors and methods of use thereof
|
WO2020092455A2
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
WO2020131586A2
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
CN113474840A
(en)
|
2018-12-21 |
2021-10-01 |
百欧恩泰美国公司 |
Methods and systems for predicting HLA class II specific epitopes and characterizing CD4+ T cells
|
AU2020233284A1
(en)
|
2019-03-01 |
2021-09-16 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
US20220143087A1
(en)
|
2019-03-08 |
2022-05-12 |
Klinikum Der Universitat Munchen |
Ccr8 expressing lymphocytes for targeted tumor therapy
|
US20220154282A1
(en)
|
2019-03-12 |
2022-05-19 |
The Broad Institute, Inc. |
Detection means, compositions and methods for modulating synovial sarcoma cells
|
US20220142948A1
(en)
|
2019-03-18 |
2022-05-12 |
The Broad Institute, Inc. |
Compositions and methods for modulating metabolic regulators of t cell pathogenicity
|
GB201903767D0
(en)
|
2019-03-19 |
2019-05-01 |
Quadrucept Bio Ltd |
Multimers, tetramers & octamers
|
US20220235340A1
(en)
|
2019-05-20 |
2022-07-28 |
The Broad Institute, Inc. |
Novel crispr-cas systems and uses thereof
|
WO2020243371A1
(en)
|
2019-05-28 |
2020-12-03 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
CR20210687A
(en)
|
2019-06-25 |
2022-03-03 |
Gilead Sciences Inc |
Flt3l-fc fusion proteins and methods of use
|
CN114302733A
(en)
*
|
2019-07-03 |
2022-04-08 |
里珍纳龙药品有限公司 |
anti-New York esophageal squamous cell carcinoma 1(NY-ESO-1) antigen binding proteins and methods of use thereof
|
CN112300268A
(en)
*
|
2019-08-02 |
2021-02-02 |
广东香雪精准医疗技术有限公司 |
High affinity T cell receptors recognizing NY-ESO-1 antigens
|
WO2021030182A1
(en)
|
2019-08-09 |
2021-02-18 |
A2 Biotherapeutics, Inc. |
Bifunctional single variable domain t cell receptors and uses thereof
|
CN114555791A
(en)
|
2019-08-13 |
2022-05-27 |
伦敦国王学院 |
IL-1 superfamily spatio-temporally restricted active cytokine-armed immunoresponsive cells
|
WO2021030627A1
(en)
|
2019-08-13 |
2021-02-18 |
The General Hospital Corporation |
Methods for predicting outcomes of checkpoint inhibition and treatment thereof
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
US20210277129A1
(en)
|
2020-02-14 |
2021-09-09 |
Jounce Therapeutics, Inc. |
Antibodies and fusion proteins that bind to ccr8 and uses thereof
|
WO2021190980A1
(en)
|
2020-03-22 |
2021-09-30 |
Quadrucept Bio Limited |
Multimers for viral strain evolution
|
CN111690051B
(en)
*
|
2020-06-28 |
2021-08-17 |
英威福赛生物技术有限公司 |
Specific T cell receptor targeting NY-ESO-1(157-165) epitope and anti-tumor application
|
US20220125884A1
(en)
|
2020-10-22 |
2022-04-28 |
Gilead Sciences, Inc. |
INTERLEUKIN-2-Fc FUSION PROTEINS AND METHODS OF USE
|