AT404561T - new adenine - Google Patents

new adenine

Info

Publication number
AT404561T
AT404561T AT02717152T AT02717152T AT404561T AT 404561 T AT404561 T AT 404561T AT 02717152 T AT02717152 T AT 02717152T AT 02717152 T AT02717152 T AT 02717152T AT 404561 T AT404561 T AT 404561T
Authority
AT
Austria
Prior art keywords
new adenine
adenine
new
Prior art date
Application number
AT02717152T
Other languages
German (de)
Inventor
Yoshiaki Isobe
Haruhisa Ogita
Masanori Tobe
Haruo Takaku
Tetsuhiro Ogino
Ayumu Kurimoto
Hajime Kawakami
Original Assignee
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2001118232 priority Critical
Application filed by Dainippon Sumitomo Pharma Co filed Critical Dainippon Sumitomo Pharma Co
Publication of AT404561T publication Critical patent/AT404561T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulfur or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16Heterocyclic compounds containing purine ring systems with oxygen, sulfur or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulfur or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulfur or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulfur or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/24Heterocyclic compounds containing purine ring systems with oxygen, sulfur or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulfur or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • C07D473/34Nitrogen atom attached in position 6, e.g. adenine
AT02717152T 2001-04-17 2002-04-15 new adenine AT404561T (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2001118232 2001-04-17

Publications (1)

Publication Number Publication Date
AT404561T true AT404561T (en) 2008-08-15

Family

ID=18968657

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02717152T AT404561T (en) 2001-04-17 2002-04-15 new adenine

Country Status (11)

Country Link
US (2) US7157465B2 (en)
EP (1) EP1386923B1 (en)
JP (1) JP4331944B2 (en)
KR (1) KR100892614B1 (en)
CN (1) CN1250548C (en)
AT (1) AT404561T (en)
CA (1) CA2444130C (en)
DE (1) DE60228229D1 (en)
ES (1) ES2314042T3 (en)
TW (1) TWI331150B (en)
WO (1) WO2002085905A1 (en)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008531580A (en) * 2000-12-08 2008-08-14 スリーエム イノベイティブ プロパティズ カンパニー Compositions and methods for targeted delivery of an immune response modifier
US7241890B2 (en) 2001-10-30 2007-07-10 Conforma Therapeutics Corporation Purine analogs having HSP90-inhibiting activity
US7321033B2 (en) 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
AU2004220469B2 (en) 2001-11-29 2010-07-29 3M Innovative Properties Company Methods of improving skin quality
ES2279903T3 (en) * 2001-12-18 2007-09-01 Cv Therapeutics, Inc. Antagonists adenosine A2a receptor.
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
ES2355819T3 (en) 2002-08-15 2011-03-31 3M Innovative Properties Company Immunostimulatory compositions and methods for stimulating an immune response.
AU2004244962A1 (en) 2003-04-10 2004-12-16 3M Innovative Properties Company Delivery of immune response modifier compounds using metal-containing particulate support materials
EP1550662B1 (en) 2002-09-27 2012-07-04 Dainippon Sumitomo Pharma Co., Ltd. Adenine compound and use thereof
EP2572715A1 (en) 2002-12-30 2013-03-27 3M Innovative Properties Company Immunostimulatory Combinations
AU2004218349A1 (en) 2003-03-04 2004-09-16 3M Innovative Properties Company Prophylactic treatment of UV-induced epidermal neoplasia
US20040192585A1 (en) 2003-03-25 2004-09-30 3M Innovative Properties Company Treatment for basal cell carcinoma
WO2005018551A2 (en) 2003-08-12 2005-03-03 3M Innovative Properties Company Oxime substituted imidazo-containing compounds
MY145983A (en) 2003-08-27 2012-05-31 3M Innovative Properties Co Aryloxy and arylalkyleneoxy substituted imidazoquinolines
DE602004026891D1 (en) 2003-09-05 2010-06-10 Anadys Pharmaceuticals Inc TLR7 ligand for treatment of hepatitis c
JP2007504269A (en) 2003-09-05 2007-03-01 スリーエム イノベイティブ プロパティズ カンパニー Cd5 + b method for the treatment of cell lymphoma
AU2004274507B2 (en) 2003-09-18 2010-08-19 Conforma Therapeutics Corporation Novel heterocyclic compounds as HSP90-inhibitors
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
RU2412942C2 (en) 2003-10-03 2011-02-27 3М Инновейтив Пропертиз Компани Oxy-substituted imidazoquinolines, capable of modulating biosynthesis of cytokines
JP2007511527A (en) 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー Oxime-substituted imidazo ring compounds
WO2005048945A2 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Hydroxylamine substituted imidazo ring compounds
EP1687307B1 (en) 2003-11-25 2016-01-06 3M Innovative Properties Company Substituted imidazo ring systems and methods
US8940755B2 (en) 2003-12-02 2015-01-27 3M Innovative Properties Company Therapeutic combinations and methods including IRM compounds
US20050226878A1 (en) * 2003-12-02 2005-10-13 3M Innovative Properties Company Therapeutic combinations and methods including IRM compounds
JP4970048B2 (en) 2003-12-22 2012-07-04 カトリーケ・ウニフェルジテイト・ルーベン・カー・イュー・ルーベン・アール・アンド・ディKatholieke Universiteit Leuven,K.U.Leuven R&D Imidazo [4,5-c] pyridine compounds and methods of antiviral therapy
EP1701955A1 (en) 2003-12-29 2006-09-20 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
WO2005066169A2 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
WO2005094531A2 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
EP1728792A4 (en) * 2004-03-26 2010-12-15 Dainippon Sumitomo Pharma Co 8-oxoadenine compound
AU2005226359B2 (en) 2004-03-26 2011-02-03 Astrazeneca Aktiebolag 9-substituted 8-oxoadenine compound
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US7915281B2 (en) 2004-06-18 2011-03-29 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
WO2006009832A1 (en) * 2004-06-18 2006-01-26 3M Innovative Properties Company Substituted imidazo ring systems and methods
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US20090208456A1 (en) * 2004-07-27 2009-08-20 Gilead Sciences, Inc. Imidazo[4,5-d]pyrimidines, their uses and methods of preparation
WO2006026470A2 (en) * 2004-08-27 2006-03-09 3M Innovative Properties Company Hiv immunostimulatory compositions
CA2589529C (en) 2004-12-17 2013-09-10 Anadys Pharmaceuticals, Inc. 3,5-disubstituted and 3,5,7-trisubstituted-3h-oxazolo and 3h-thiazolo [4,5-d]pyrimidin-2-one compounds and prodrugs thereof
US20060252791A1 (en) 2004-12-21 2006-11-09 Gilead Sciences, Inc. Imidazo[4,5-c]pyridine compound and method of antiviral treatment
ES2392648T3 (en) 2004-12-30 2012-12-12 3M Innovative Properties Company Chiral compounds containing a nucleus substituted 1,2-imidazo-4,5-c condensate
WO2006074003A2 (en) 2004-12-30 2006-07-13 3M Innovative Properties Company CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
US7968563B2 (en) 2005-02-11 2011-06-28 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
AU2006232375A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
CA2602683A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
WO2006117670A1 (en) 2005-05-04 2006-11-09 Pfizer Limited 2-amido-6-amino-8-oxopurine derivatives as toll-like receptor modulators for the treatment of cancer and viral infections, such as hepatitis c
EP1909564A4 (en) 2005-07-18 2010-06-30 Novartis Ag Small animal model for hcv replication
JP2009504803A (en) 2005-08-22 2009-02-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents of The University of California Tlr agonist
WO2007028129A1 (en) * 2005-09-02 2007-03-08 Pfizer Inc. Hydroxy substituted 1h-imidazopyridines and methods
TW200801003A (en) * 2005-09-16 2008-01-01 Astrazeneca Ab Novel compounds
US20080269240A1 (en) * 2005-09-22 2008-10-30 Dainippon Sumitomo Pharma Co., Ltd. a corporation of Japan Novel Adenine Compound
JPWO2007034917A1 (en) 2005-09-22 2009-03-26 大日本住友製薬株式会社 The novel adenine compound
WO2007034916A1 (en) * 2005-09-22 2007-03-29 Dainippon Sumitomo Pharma Co., Ltd. Novel adenine compound
WO2007034881A1 (en) * 2005-09-22 2007-03-29 Dainippon Sumitomo Pharma Co., Ltd. Novel adenine compound
WO2007034817A1 (en) 2005-09-22 2007-03-29 Dainippon Sumitomo Pharma Co., Ltd. Novel adenine compound
TW200745114A (en) * 2005-09-22 2007-12-16 Astrazeneca Ab Novel compounds
CA2630463C (en) 2005-11-21 2015-01-06 Anadys Pharmaceuticals, Inc. Novel process for the preparation of 5-amino-3h-thiazolo[4,5-d]pyrimidin-2-one
US20090285834A1 (en) 2005-11-24 2009-11-19 Dainippon Sumitomo Pharma Co., Ltd. Novel memory ctl induction potentiator
EP2086582B1 (en) 2006-10-12 2012-11-14 GlaxoSmithKline Biologicals s.a. Vaccine comprising an oil in water emulsion adjuvant
ES2536426T3 (en) 2006-03-23 2015-05-25 Novartis Ag Imidazoquinoxaline compounds as immunomodulators
CA2653941C (en) * 2006-05-31 2013-01-08 The Regents Of The University Of California Substituted amino purine derivatives and uses thereof
CN101516192B (en) 2006-06-22 2012-09-19 安那迪斯药品股份有限公司 Prodrugs of 5-amino-3-(3'-deoxy-beta-d-ribofuranosyl)-thiazolo[4,5-d] pyrimidin-2,7-dione
US8138172B2 (en) * 2006-07-05 2012-03-20 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of TLR7
NZ574312A (en) 2006-07-07 2012-02-24 Gilead Sciences Inc Novel pyridazine compound and use thereof
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
DE602007012881D1 (en) 2006-07-18 2011-04-14 Anadys Pharmaceuticals Inc Carbonat- und carbamat-prodrugs von thiazolo ä4,5-dü-pyrimidinen
TW200908994A (en) 2007-04-20 2009-03-01 Glaxosmithkline Biolog Sa Vaccine
TW200831105A (en) * 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
AU2008227128B2 (en) 2007-02-07 2012-12-06 The Regents Of The University Of California Conjugates of synthetic TLR agonists and uses therefor
US8067413B2 (en) 2007-03-19 2011-11-29 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7 ) modulators
EP2139894B1 (en) * 2007-03-19 2011-10-26 AstraZeneca AB 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
TW200902018A (en) * 2007-03-20 2009-01-16 Dainippon Sumitomo Pharma Co Novel adenine compound
EP2138497A4 (en) * 2007-03-20 2012-01-04 Dainippon Sumitomo Pharma Co Novel adenine compound
US8436178B2 (en) * 2007-05-08 2013-05-07 Astrazeneca Ab Imidazoquinolines with immuno-modulating properties
CA2691917C (en) 2007-07-06 2013-12-03 Gilead Sciences, Inc. Crystalline pyridazine compound
PE12362009A1 (en) * 2007-11-22 2009-09-16 Astrazeneca Ab Pyrimidine derivatives as immunomodulators TLR7
PE11562009A1 (en) 2007-12-17 2009-09-03 Astrazeneca Ab Salts (3 - {[[3- (6-amino-2-butoxy-8-oxo-7,8-dihydro-9 H -purin-9-yl) propyl] (3-morpholin-4-ylpropyl) amino] methyl} phenyl) acetate
SI2222710T1 (en) 2007-12-24 2016-11-30 Id Biomedical Corporation Of Quebec Recombinant rsv antigens
JPWO2009091031A1 (en) * 2008-01-17 2011-05-26 大日本住友製薬株式会社 Method for producing adenine compound
US8865896B2 (en) 2008-01-17 2014-10-21 Astrazeneca Aktiebolag Method for preparing adenine compound
WO2009099650A2 (en) * 2008-02-07 2009-08-13 Carson Dennis A Treatment of bladder diseases with a tlr7 activator
JP5749642B2 (en) 2008-04-16 2015-07-15 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム vaccine
WO2010033074A1 (en) * 2008-09-18 2010-03-25 Astrazeneca Ab Use of a tlr7 agonist for the treatment of cancer
EP2346508B1 (en) 2008-09-26 2016-08-24 Intellikine, LLC Heterocyclic kinase inhibitors
WO2010063865A1 (en) 2008-12-03 2010-06-10 Proyecto De Biomedicina Cima, S.L. Use of phenol-soluble modulins for vaccine development
WO2010088924A1 (en) 2009-02-06 2010-08-12 Telormedix Sa Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
EP2396328A2 (en) * 2009-02-11 2011-12-21 The Regents of The University of California Toll-like receptor modulators and treatment of diseases
KR20120030436A (en) 2009-05-21 2012-03-28 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases
GB0908772D0 (en) * 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
AU2010264686A1 (en) 2009-06-24 2012-01-19 Glaxosmithkline Biologicals S.A. Vaccine
SI2445526T1 (en) 2009-06-24 2016-08-31 Glaxosmithkline Biologicals S.A. Recombinant rsv antigens
ES2644286T3 (en) 2009-10-22 2017-11-28 Gilead Sciences, Inc. Purine or deazapurine derivatives useful for the treatment of (among others) viral infections
GB0919117D0 (en) 2009-10-30 2009-12-16 Glaxosmithkline Biolog Sa Process
WO2011068233A1 (en) * 2009-12-03 2011-06-09 Dainippon Sumitomo Pharma Co., Ltd. Imidazoquinolines which act via toll - like receptors (tlr)
US20110150836A1 (en) * 2009-12-22 2011-06-23 Gilead Sciences, Inc. Methods of treating hbv and hcv infection
WO2011101332A1 (en) 2010-02-16 2011-08-25 Proyecto De Biomedicina Cima, S.L. Compositions based on the fibronectin extracellular domain a for the treatment of melanoma
EP2563404B1 (en) 2010-04-30 2016-09-21 Urogen Pharma Ltd. Phospholipid drug analogs
US9050319B2 (en) 2010-04-30 2015-06-09 Telormedix, Sa Phospholipid drug analogs
GB201009273D0 (en) 2010-06-03 2010-07-21 Glaxosmithkline Biolog Sa Novel vaccine
WO2012080728A1 (en) 2010-12-16 2012-06-21 Astrazeneca Ab Imidazo [4, 5 -c] quinolin- 1 -yl derivative useful in therapy
DK2651943T3 (en) 2010-12-17 2017-06-06 Sumitomo Dainippon Pharma Co Ltd purine derivatives
EP2505640A1 (en) 2011-03-29 2012-10-03 Neo Virnatech, S.L. Vaccine compositions for birnavirus-borne diseases
GB201120000D0 (en) 2011-11-20 2012-01-04 Glaxosmithkline Biolog Sa Vaccine
JP2015514696A (en) 2012-03-18 2015-05-21 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Vaccination method against human papillomavirus
BR112014029261A2 (en) 2012-05-18 2017-06-27 Astrazeneca Ab carboxylic acid compounds
JP2015525794A (en) 2012-08-06 2015-09-07 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Method for eliciting an immune response against RSV and Bordetella pertussis in infants
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
US20160193322A1 (en) 2013-08-05 2016-07-07 Glaxosmithkline Biologicals S.A. Combination immunogenic compositions
EP2952893A1 (en) 2014-06-04 2015-12-09 Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Method for detecting antibody-secreting B cells specific for HLA
JP2017526730A (en) 2014-09-16 2017-09-14 ギリアード サイエンシーズ, インコーポレイテッド Solid form of Toll-like receptor modulator
CA2977493A1 (en) 2015-03-03 2016-09-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Display platform from bacterial spore coat proteins
CA2998995A1 (en) 2015-09-29 2017-04-06 Astrazeneca Aktiebolag Adenine conjugate compounds and their use as vaccine adjuvants
WO2018109220A2 (en) 2016-12-16 2018-06-21 Institute For Research In Biomedicine Novel recombinant prefusion rsv f proteins and uses thereof
WO2018162450A1 (en) 2017-03-06 2018-09-13 Fundación Para La Investigación Médica Aplicada New inmunostimulatory compositions comprising an entity of cold inducible rna-binding protein with an antigen for the activation of dendritic cells
WO2018193063A2 (en) 2017-04-19 2018-10-25 Institute For Research In Biomedicine Novel malaria vaccines and antibodies binding to plasmodium sporozoites
US20190055245A1 (en) 2017-08-16 2019-02-21 Bristol-Myers Squibb Company Toll-like receptor 7 (tlr7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor
US20190055243A1 (en) 2017-08-16 2019-02-21 Bristol-Myers Squibb Company Toll-like receptor 7 (tlr7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor
US20190055247A1 (en) 2017-08-16 2019-02-21 Bristol-Myers Squibb Company Toll-like receptor 7 (tlr7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor
US20190055246A1 (en) 2017-08-16 2019-02-21 Bristol-Myers Squibb Company Toll-like receptor 7 (tlr7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor
US20190055244A1 (en) 2017-08-16 2019-02-21 Bristol-Myers Squibb Company Toll-like receptor 7 (tlr7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US191086A (en) * 1877-05-22 Improvement in cattle-stalls
US2705715A (en) * 1952-10-29 1955-04-05 American Cyanamid Co Purine compounds and methods of preparing the same
JPS4816519B1 (en) * 1969-08-22 1973-05-22
IL73534A (en) * 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
ZA8408968B (en) * 1983-11-18 1986-06-25 Riker Laboratories Inc 1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines
DE3517709A1 (en) * 1985-01-05 1986-07-10 Bayer Ag Basic preparations of quinolone carboxylic acids
IL78643D0 (en) * 1985-05-02 1986-08-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
US4772606A (en) * 1985-08-22 1988-09-20 Warner-Lambert Company Purine derivatives
JPH08165292A (en) 1993-10-07 1996-06-25 Boryung Pharm Co Ltd Adenine derivative, its production and use
US6028076A (en) * 1996-07-03 2000-02-22 Japan Energy Corporation Purine derivative
US6329381B1 (en) * 1997-11-28 2001-12-11 Sumitomo Pharmaceuticals Company, Limited Heterocyclic compounds
JP4189048B2 (en) 1997-12-26 2008-12-03 大日本住友製薬株式会社 Heterocyclic compounds
CZ27399A3 (en) 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituted nitrogen heterocyclic derivatives process of their preparation, the derivatives employed as medicaments, pharmaceutical composition and a compound pharmaceutical preparation in which these derivatives are comprised as well as use of these derivatives for preparing medicaments
ES2279903T3 (en) * 2001-12-18 2007-09-01 Cv Therapeutics, Inc. Antagonists adenosine A2a receptor.
EP1550662B1 (en) * 2002-09-27 2012-07-04 Dainippon Sumitomo Pharma Co., Ltd. Adenine compound and use thereof

Also Published As

Publication number Publication date
KR100892614B1 (en) 2009-04-09
EP1386923A1 (en) 2004-02-04
CN1512992A (en) 2004-07-14
TWI331150B (en) 2010-10-01
EP1386923B1 (en) 2008-08-13
US7157465B2 (en) 2007-01-02
EP1386923A4 (en) 2005-08-31
CN1250548C (en) 2006-04-12
DE60228229D1 (en) 2008-09-25
US20070037832A1 (en) 2007-02-15
WO2002085905A1 (en) 2002-10-31
US7521454B2 (en) 2009-04-21
CA2444130A1 (en) 2002-10-31
ES2314042T3 (en) 2009-03-16
JP4331944B2 (en) 2009-09-16
CA2444130C (en) 2010-12-21
US20040132748A1 (en) 2004-07-08
JPWO2002085905A1 (en) 2004-08-12
KR20040008156A (en) 2004-01-28

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