AT386039T - Pyrimidine derivatives and their use for the production of a triazolo-pyrimidine nucleoside carba - Google Patents

Pyrimidine derivatives and their use for the production of a triazolo-pyrimidine nucleoside carba

Info

Publication number
AT386039T
AT386039T AT01937111T AT01937111T AT386039T AT 386039 T AT386039 T AT 386039T AT 01937111 T AT01937111 T AT 01937111T AT 01937111 T AT01937111 T AT 01937111T AT 386039 T AT386039 T AT 386039T
Authority
AT
Austria
Prior art keywords
pyrimidine
carba
triazolo
production
use
Prior art date
Application number
AT01937111T
Other languages
German (de)
Inventor
Ulf Larsson
Mattias Magnusson
Tibor Musil
Andreas Palmgren
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to GB0013488A priority Critical patent/GB0013488D0/en
Priority to SE0002102A priority patent/SE0002102D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AT386039T publication Critical patent/AT386039T/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26244413&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT386039(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulfur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
AT01937111T 2000-06-02 2001-05-31 Pyrimidine derivatives and their use for the production of a triazolo-pyrimidine nucleoside carba AT386039T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB0013488A GB0013488D0 (en) 2000-06-02 2000-06-02 Chemical compound
SE0002102A SE0002102D0 (en) 2000-06-02 2000-06-06 Chemical compound

Publications (1)

Publication Number Publication Date
AT386039T true AT386039T (en) 2008-03-15

Family

ID=26244413

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01937111T AT386039T (en) 2000-06-02 2001-05-31 Pyrimidine derivatives and their use for the production of a triazolo-pyrimidine nucleoside carba

Country Status (36)

Country Link
US (6) US7067663B2 (en)
EP (1) EP1299390B1 (en)
JP (1) JP4947870B2 (en)
KR (2) KR100802884B1 (en)
CN (3) CN100354268C (en)
AR (1) AR028605A1 (en)
AT (1) AT386039T (en)
AU (4) AU2001262876B2 (en)
BG (1) BG65866B1 (en)
BR (1) BR0111319A (en)
CA (1) CA2408914C (en)
CY (1) CY1108101T1 (en)
CZ (3) CZ303162B6 (en)
DE (1) DE60132776T2 (en)
DK (1) DK1299390T3 (en)
EE (1) EE05223B1 (en)
ES (1) ES2299487T3 (en)
GB (1) GB0013488D0 (en)
HK (1) HK1053122A1 (en)
HU (1) HU229281B1 (en)
IL (3) IL152776D0 (en)
IS (1) IS2600B (en)
MX (2) MXPA02011793A (en)
MY (1) MY131942A (en)
NO (1) NO324266B1 (en)
NZ (1) NZ522637A (en)
PL (3) PL212128B1 (en)
PT (1) PT1299390E (en)
RU (1) RU2295526C2 (en)
SE (1) SE0002102D0 (en)
SI (1) SI1299390T1 (en)
SK (1) SK286845B6 (en)
TW (1) TWI285203B (en)
UA (1) UA73182C2 (en)
WO (1) WO2001092263A1 (en)
ZA (1) ZA200209068B (en)

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WO2010030224A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab A process for preparing [1s- [1-alpha, 2-alpha, 3-beta (1s*, 2r*) 5-beta] ] -3- [7- [2- (3, 4-dif luorophenyl) -cyclopropylamino] - 5- (propylthio) -3h-1, 2, 3-triazolo [4, 5-d] pyrimidin-3-yl] -5- (2- hydroxyethoxy) cyclopentane-1, 2-diol and to its intermediates
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EP2588441A2 (en) * 2010-06-30 2013-05-08 Actavis Group Ptc Ehf Novel processes for the preparation of phenylcyclopropylamine derivatives and use thereof for preparing ticagrelor
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US9469614B2 (en) 2011-10-27 2016-10-18 Lek Pharmaceuticals D.D. Synthesis of triazolopyrimidine compounds
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EP2794575B1 (en) 2011-12-23 2018-12-05 LEK Pharmaceuticals d.d. Synthesis of triazolopyrimidine compounds
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EP2644590A1 (en) 2012-03-30 2013-10-02 LEK Pharmaceuticals d.d. Synthesis of 2-(3,4-difluorophenyl)cyclopropanamine derivatives and salts
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CN102675321B (en) * 2012-05-11 2014-12-10 上海皓元化学科技有限公司 Preparation method of ticagrelor
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CN102875537A (en) * 2012-09-10 2013-01-16 常州制药厂有限公司 Novel preparation method of antithrombosis medicine
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CN103848834B (en) * 2012-12-06 2017-09-22 博瑞生物医药(苏州)股份有限公司 A process and intermediates for the preparation of ticagrelor
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CN103936767B (en) * 2013-01-23 2016-08-03 上海医药工业研究院 ] Decane method
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CN107573333A (en) 2013-04-10 2018-01-12 江苏恒瑞医药股份有限公司 Intermediate of ticagrelor and preparation method thereof and preparation method of ticagrelor
CN103275056B (en) * 2013-05-24 2015-06-17 浙江普洛医药科技有限公司 Preparation method of ticagrelor midbody
WO2014195861A2 (en) * 2013-06-04 2014-12-11 Dr. Reddy’S Laboratories Limited Preparation of ticagrelor
CN104230818B (en) * 2013-06-06 2018-01-12 郝聪梅 Improved methods for preparing intermediates Kage Lei
WO2014206187A1 (en) * 2013-06-24 2014-12-31 苏州明锐医药科技有限公司 Preparation method of ticagrelor and intermediates thereof
CN103275087A (en) * 2013-06-28 2013-09-04 南京工业大学 Triazolo pyrimidine derivative and preparation method thereof
CN104341402B (en) * 2013-07-23 2018-04-27 博瑞生物医药(苏州)股份有限公司 A method for the preparation of Intermediate ticagrelor
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Also Published As

Publication number Publication date
BG107333A (en) 2003-07-31
NO324266B1 (en) 2007-09-17
PL210375B1 (en) 2012-01-31
HK1053122A1 (en) 2008-08-01
DK1299390T3 (en) 2008-05-26
EE05223B1 (en) 2009-10-15
IL225893A (en) 2015-08-31
RU2295526C2 (en) 2007-03-20
SE0002102D0 (en) 2000-06-06
DE60132776D1 (en) 2008-03-27
NO20025719L (en) 2003-02-03
EP1299390B1 (en) 2008-02-13
US8273879B2 (en) 2012-09-25
KR20030007828A (en) 2003-01-23
KR100814229B1 (en) 2008-03-17
US20060041132A1 (en) 2006-02-23
AU6287601A (en) 2001-12-11
SK16832002A3 (en) 2003-06-03
NO20025719D0 (en) 2002-11-28
IS2600B (en) 2010-04-15
PL392726A1 (en) 2010-12-06
PL392725A1 (en) 2010-12-06
CY1108101T1 (en) 2014-02-12
JP4947870B2 (en) 2012-06-06
US20100004444A1 (en) 2010-01-07
AU2007200776B2 (en) 2009-11-19
JP2003535093A (en) 2003-11-25
CA2408914A1 (en) 2001-12-06
AR028605A1 (en) 2003-05-14
TWI285203B (en) 2007-08-11
HU0302345A3 (en) 2007-10-29
AU2007200776A1 (en) 2007-03-15
NZ522637A (en) 2004-09-24
EP1299390A1 (en) 2003-04-09
DE60132776T2 (en) 2009-02-12
US7381828B2 (en) 2008-06-03
PL212128B1 (en) 2012-08-31
CN101143864A (en) 2008-03-19
CZ20023919A3 (en) 2003-05-14
AU2010200461B2 (en) 2011-08-18
CN1680340A (en) 2005-10-12
IS6614A (en) 2002-11-14
MXPA02011793A (en) 2003-04-10
US20030148888A1 (en) 2003-08-07
UA73182C2 (en) 2003-03-17
SI1299390T1 (en) 2008-06-30
BR0111319A (en) 2003-06-03
KR100802884B1 (en) 2008-02-13
CZ302645B6 (en) 2011-08-10
MX336939B (en) 2016-02-08
WO2001092263A1 (en) 2001-12-06
US7067663B2 (en) 2006-06-27
CZ302644B6 (en) 2011-08-10
BG65866B1 (en) 2010-03-31
IL152776A (en) 2013-06-27
HU0302345A2 (en) 2003-11-28
SK286845B6 (en) 2009-06-05
MY131942A (en) 2007-09-28
CA2408914C (en) 2009-12-29
IL225893D0 (en) 2013-06-27
CN1200940C (en) 2005-05-11
AU2001262876B2 (en) 2007-03-01
CN1432017A (en) 2003-07-23
IL152776D0 (en) 2003-06-24
PT1299390E (en) 2008-04-17
PL211318B1 (en) 2012-05-31
US20070049755A1 (en) 2007-03-01
KR20080003458A (en) 2008-01-07
ES2299487T3 (en) 2008-06-01
US20080234481A1 (en) 2008-09-25
US20110218330A1 (en) 2011-09-08
CZ303162B6 (en) 2012-05-09
ZA200209068B (en) 2003-12-02
CN100354268C (en) 2007-12-12
EE200200669A (en) 2004-06-15
AU2010200461A1 (en) 2010-02-25
HU229281B1 (en) 2013-10-28
GB0013488D0 (en) 2000-07-26
PL359183A1 (en) 2004-08-23

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