AT375385T - Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells - Google Patents

Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells

Info

Publication number
AT375385T
AT375385T AT05729822T AT05729822T AT375385T AT 375385 T AT375385 T AT 375385T AT 05729822 T AT05729822 T AT 05729822T AT 05729822 T AT05729822 T AT 05729822T AT 375385 T AT375385 T AT 375385T
Authority
AT
Austria
Prior art keywords
serum
production
culture medium
cell culture
mammalian cells
Prior art date
Application number
AT05729822T
Other languages
German (de)
Inventor
Yehoshua Aloni
Orit Aharonovitz
Thierry Ziegler
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP04100800 priority Critical
Priority to US55117104P priority
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of AT375385T publication Critical patent/AT375385T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0043Medium free of human- or animal-derived components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/70Undefined extracts
    • C12N2500/76Undefined extracts from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/33Insulin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
AT05729822T 2004-03-01 2005-02-28 Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells AT375385T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04100800 2004-03-01
US55117104P true 2004-03-08 2004-03-08

Publications (1)

Publication Number Publication Date
AT375385T true AT375385T (en) 2007-10-15

Family

ID=34928882

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05729822T AT375385T (en) 2004-03-01 2005-02-28 Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells

Country Status (19)

Country Link
US (1) US7553665B2 (en)
EP (1) EP1720979B1 (en)
JP (1) JP4713567B2 (en)
AT (1) AT375385T (en)
AU (1) AU2005217154B2 (en)
CA (1) CA2554238C (en)
CY (1) CY1107014T1 (en)
DE (1) DE602005002829T2 (en)
DK (1) DK1720979T3 (en)
ES (1) ES2292127T3 (en)
HR (1) HRP20070474T3 (en)
IL (1) IL177493A (en)
ME (1) ME01218B (en)
NO (1) NO335825B1 (en)
PL (1) PL1720979T3 (en)
PT (1) PT1720979E (en)
RS (1) RS50531B (en)
SI (1) SI1720979T1 (en)
WO (1) WO2005083058A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201305214A (en) * 2000-02-10 2013-02-01 Abbott Gmbh & Co Kg Antibodies that bind human interleukin-18 and methods of making and using
EA010096B1 (en) 2003-03-11 2008-06-30 Лаборатуар Сероно Са Expression vectors comprising the mcmv ie2 promoter
AT549353T (en) * 2003-05-13 2012-03-15 Merck Serono Sa Active variations of il-18 binding protein and its medical uses
EP1675956B1 (en) 2003-10-21 2010-10-13 Merck Serono SA Minimal dna sequence acting as a chromatin insulator and its use in protein expression
ES2285543T3 (en) * 2003-11-05 2007-11-16 Ares Trading S.A. Procedure for the purification of protein from union to il-18.
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
EP1761552B1 (en) * 2004-06-29 2008-09-17 Ares Trading S.A. Process for the purification of il-18 binding protein
JP5414178B2 (en) * 2004-12-23 2014-02-12 メディミューン,エルエルシー Non-tumorigenic MDCK cell line for virus propagation
EP1885753B1 (en) * 2005-06-03 2011-07-27 Ares Trading S.A. Production of recombinant Il-18 binding protein
SI1891088T1 (en) * 2005-06-10 2012-02-29 Ares Trading Sa Process for the purification of il-18 binding protein
EP2615167A1 (en) * 2006-09-15 2013-07-17 MedImmune, LLC Method for eliminating DNA contaminants from viral preparations
BRPI0812603A2 (en) 2007-07-09 2015-03-03 Genentech Inc "METHOD TO PREVENT DISULFECT BRIDGE REDUCTION"
EP2344634A4 (en) * 2008-09-24 2012-08-29 Medimmune Llc Methods for cultivating cells, propagating and purifying viruses
DE102008051574A1 (en) * 2008-10-14 2010-04-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method for extracting a protein with interferon-beta-activity, comprises culturing cells with the ability to synthesize the protein in a culture medium containing a block copolymer of ethylene oxide and propylene oxide
RU2017138926A (en) * 2009-08-11 2019-02-11 Дженентек, Инк. PRODUCTION OF PROTEINS IN CULTURAL MEDIA WITHOUT GLUTAMINE
RU2728188C2 (en) * 2014-07-16 2020-07-28 Хартсид Инк. Method for inducing undifferentiated stem cell death without cardiomyocyte death induction and cardiomyocyte recovery method (versions)
CN106676053B (en) * 2016-12-31 2020-08-25 山东甲骨文生物科技有限公司 Low-serum cell culture medium with wide adaptability and preparation method thereof
CN107574150A (en) * 2017-09-06 2018-01-12 万向东方生物科技有限公司 A kind of serum-free immune cell media and preparation method thereof
CN108102982A (en) * 2018-02-07 2018-06-01 山东出入境检验检疫局检验检疫技术中心 The vacuum freeze drying protective agent and its method for preserving of Maxwell vibrios

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0249579A (en) * 1988-02-29 1990-02-19 Kyowa Hakko Kogyo Co Ltd Culture medium
WO1996026266A1 (en) 1995-02-23 1996-08-29 Quest International B.V. Peptides for tissue and cell culture media
EP1983044B1 (en) * 1996-10-10 2016-08-10 Life Technologies Corporation Animal cell culture media comprising plant-derived nutrients
IL121860D0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
US6406909B1 (en) * 1998-07-10 2002-06-18 Chugai Seiyaku Kabushiki Kaisha Serum-free medium for culturing animal cells
AT409379B (en) 1999-06-02 2002-07-25 Baxter Ag Medium for protein- and serum-free cell culture
AR025446A1 (en) 1999-09-03 2002-11-27 Applied Research Systems METHOD TO PRODUCE A SEGREGATED HETEROLOGICAL PROTEin FROM CHINESE HAMSTER OVARIAN CELLS CULTIVATED ON MICROCARRIERS.
US20030096414A1 (en) 2001-03-27 2003-05-22 Invitrogen Corporation Culture medium for cell growth and transfection
DK2287288T3 (en) * 2002-07-09 2013-01-07 Baxter Int Medium free of animal protein for cell culture
EA010096B1 (en) 2003-03-11 2008-06-30 Лаборатуар Сероно Са Expression vectors comprising the mcmv ie2 promoter
AT549353T (en) * 2003-05-13 2012-03-15 Merck Serono Sa Active variations of il-18 binding protein and its medical uses
EP1675956B1 (en) * 2003-10-21 2010-10-13 Merck Serono SA Minimal dna sequence acting as a chromatin insulator and its use in protein expression
ES2285543T3 (en) * 2003-11-05 2007-11-16 Ares Trading S.A. Procedure for the purification of protein from union to il-18.
EP1761552B1 (en) * 2004-06-29 2008-09-17 Ares Trading S.A. Process for the purification of il-18 binding protein
EP1885753B1 (en) 2005-06-03 2011-07-27 Ares Trading S.A. Production of recombinant Il-18 binding protein
SI1891088T1 (en) 2005-06-10 2012-02-29 Ares Trading Sa Process for the purification of il-18 binding protein

Also Published As

Publication number Publication date
JP4713567B2 (en) 2011-06-29
SI1720979T1 (en) 2007-12-31
JP2007525228A (en) 2007-09-06
NO20064379L (en) 2006-10-19
IL177493A (en) 2010-12-30
CA2554238C (en) 2013-02-12
ES2292127T3 (en) 2008-03-01
WO2005083058A1 (en) 2005-09-09
US7553665B2 (en) 2009-06-30
CA2554238A1 (en) 2005-09-09
NO335825B1 (en) 2015-02-23
DE602005002829D1 (en) 2007-11-22
EP1720979B1 (en) 2007-10-10
DE602005002829T2 (en) 2008-07-10
US20070196895A1 (en) 2007-08-23
RS50531B (en) 2010-05-07
PT1720979E (en) 2007-10-25
CY1107014T1 (en) 2012-09-26
PL1720979T3 (en) 2008-03-31
IL177493D0 (en) 2006-12-10
AU2005217154B2 (en) 2010-02-18
ME01218B (en) 2013-06-20
AU2005217154A1 (en) 2005-09-09
HRP20070474T3 (en) 2007-11-30
EP1720979A1 (en) 2006-11-15
DK1720979T3 (en) 2007-12-10

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