AT368027T - Bipolar lipids and their use for the transport of bioactive substances - Google Patents

Bipolar lipids and their use for the transport of bioactive substances

Info

Publication number
AT368027T
AT368027T AT00925490T AT00925490T AT368027T AT 368027 T AT368027 T AT 368027T AT 00925490 T AT00925490 T AT 00925490T AT 00925490 T AT00925490 T AT 00925490T AT 368027 T AT368027 T AT 368027T
Authority
AT
Austria
Prior art keywords
transport
use
bioactive substances
bipolar lipids
lipids
Prior art date
Application number
AT00925490T
Other languages
German (de)
Inventor
Ian Blagbrough
Andrew John Geall
Michael Anthony William Eaton
Timothy John Norman
Terence Seward Baker
Andrew Neil Charles Weir
Catherine Fiona Catterall
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GBGB9909582.0A priority Critical patent/GB9909582D0/en
Priority to GBGB9924257.0A priority patent/GB9924257D0/en
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Publication of AT368027T publication Critical patent/AT368027T/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
AT00925490T 1999-04-26 2000-04-26 Bipolar lipids and their use for the transport of bioactive substances AT368027T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB9909582.0A GB9909582D0 (en) 1999-04-26 1999-04-26 Chemical compounds
GBGB9924257.0A GB9924257D0 (en) 1999-10-13 1999-10-13 Chemical compounds

Publications (1)

Publication Number Publication Date
AT368027T true AT368027T (en) 2007-08-15

Family

ID=26315471

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00925490T AT368027T (en) 1999-04-26 2000-04-26 Bipolar lipids and their use for the transport of bioactive substances

Country Status (6)

Country Link
EP (1) EP1187807B1 (en)
AT (1) AT368027T (en)
AU (1) AU4421200A (en)
DE (1) DE60035687T2 (en)
ES (1) ES2288472T3 (en)
WO (1) WO2000064858A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2298728A1 (en) 1998-11-12 2011-03-23 Life Technologies Corporation Transfection reagents
GB9919338D0 (en) 1999-08-16 1999-10-20 Celltech Therapeutics Ltd Biological products
FR2878846B1 (en) * 2004-12-07 2007-02-23 Enscr Similar compounds of membrane lipids of archaebacteria and liposomal compositions integrating of such compounds
EP3169310A1 (en) 2014-07-15 2017-05-24 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2727679B1 (en) * 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa New transfection agents and their pharmaceutical applications
AU745958B2 (en) * 1997-08-13 2002-04-11 Biontex Laboratories Gmbh Novel lipopolyamines, and the preparation and use thereof
US6583301B1 (en) * 1998-04-08 2003-06-24 Celltech R & D Limited Lipids

Also Published As

Publication number Publication date
DE60035687T2 (en) 2008-06-05
AU4421200A (en) 2000-11-10
ES2288472T3 (en) 2008-01-16
EP1187807B1 (en) 2007-07-25
WO2000064858A1 (en) 2000-11-02
DE60035687D1 (en) 2007-09-06
EP1187807A1 (en) 2002-03-20

Similar Documents

Publication Publication Date Title
DE60140708D1 (en) Prolinderivative and their use as medicines
DE69734921D1 (en) Antifog object and its manufacturing process
DE69831657D1 (en) Absorbent articles with removable elements
DE69831673D1 (en) Using exedinen and their antagonists for the reduction of food intake
AT375983T (en) Bacterial gyrase-inhibitors and their use
DE69725042D1 (en) Highly branched polyamidoamines and their preparation
NO995543D0 (en) Monoesters of probucol for the treatment of kardiovaskulaer and inflammatory disease
DE69529026D1 (en) Trehalose, their preparation and their use
DE60225719D1 (en) Cis-2,4,5-triphenyl-imidazolines and their use in the treatment of tumors
AT483199T (en) Client-side boot-domains and boot-regulate
EE04915B1 (en) Kinuklidiinderivaadid, process for preparing them, intermediate compounds, their use in the pharmaceutical composition, and
DE60043305D1 (en) Pharmaceutical preparations for the treatment of insulinresitenz
DE69739348D1 (en) Protein stabilized pharmaceutical ingredients and the use thereof
EE200200119A (en) Quinazoline derivatives and their use as medicaments
DE69821541D1 (en) The disposable absorbent article
DE60032823D1 (en) Adamantane derivatives for the treatment of inflammatory, immunological and cardiovascular diseases
DE69710487T2 (en) Stable stand-up pouches and methods for manufacturing
AT420659T (en) Criptoblockierende antibodies and their use
ATA71696A (en) New benzazepine derivatives, containing these medicines and use them for the manufacture of medicines
AT432940T (en) Substituted isoquinoline-3-carboxylic acid amides, their production and their use as medicines
AT323501T (en) A pharmaceutical composition containing proteoglycan and their use for the treatment of inflammatory diseases
DE60041128D1 (en) Nheitlichen and separate abtastsegmenten
DE60033051D1 (en) Method and device for the continuous preparation of diaryl
DE69834726D1 (en) Pha-compositions and film-pha their use for production of
NO20026159L (en) Testanrodning with means for the storage and distribution of diagnoseremser

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties