AT323771T - Fragment of human erythropoietin receptor and antibodies, but - Google Patents

Fragment of human erythropoietin receptor and antibodies, but

Info

Publication number
AT323771T
AT323771T AT94927925T AT94927925T AT323771T AT 323771 T AT323771 T AT 323771T AT 94927925 T AT94927925 T AT 94927925T AT 94927925 T AT94927925 T AT 94927925T AT 323771 T AT323771 T AT 323771T
Authority
AT
Austria
Prior art keywords
antibodies
fragment
human erythropoietin
erythropoietin receptor
receptor
Prior art date
Application number
AT94927925T
Other languages
German (de)
Inventor
Jong Y Lee
Original Assignee
Jong Y Lee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10681593A priority Critical
Application filed by Jong Y Lee filed Critical Jong Y Lee
Publication of AT323771T publication Critical patent/AT323771T/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/23Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a GST-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
AT94927925T 1993-08-16 1994-08-15 Fragment of human erythropoietin receptor and antibodies, but AT323771T (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10681593A true 1993-08-16 1993-08-16

Publications (1)

Publication Number Publication Date
AT323771T true AT323771T (en) 2006-05-15

Family

ID=22313426

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94927925T AT323771T (en) 1993-08-16 1994-08-15 Fragment of human erythropoietin receptor and antibodies, but

Country Status (7)

Country Link
US (2) US5843726A (en)
EP (1) EP0776370B1 (en)
JP (1) JPH09501833A (en)
AT (1) AT323771T (en)
CA (1) CA2169629C (en)
DE (2) DE69434704D1 (en)
WO (1) WO1995005469A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030064480A1 (en) * 1990-06-28 2003-04-03 Leander Lauffer Fusion proteins with immunoglobulin portions, the preparation and use thereof
US6142857A (en) * 1998-01-06 2000-11-07 Speedfam-Ipec Corporation Wafer polishing with improved backing arrangement
US7345019B1 (en) * 1999-04-13 2008-03-18 The Kenneth S. Warren Institute, Inc. Modulation of excitable tissue function by peripherally administered erythropoietin
WO2000061637A1 (en) * 1999-04-14 2000-10-19 Smithkline Beecham Corporation Erythropoietin receptor antibodies
US6998124B1 (en) 1999-04-14 2006-02-14 Smithkline Beecham Corporation Erythropoietin receptor antibodies
NZ518374A (en) * 1999-09-13 2006-09-29 Equitech Lab Inc A method for detecting a target analyte in a sample
KR100785648B1 (en) * 2000-04-05 2007-12-14 이종예 Detection of erythropoietin and erythropoietin receptor
US7767643B2 (en) 2000-12-29 2010-08-03 The Kenneth S. Warren Institute, Inc. Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
US20030072737A1 (en) * 2000-12-29 2003-04-17 Michael Brines Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
AT322498T (en) * 2001-07-26 2006-04-15 Tagra Biotechnologies Ltd Stabilized ascorbic acid -3- phosphate derivatives
US7396913B2 (en) 2002-10-14 2008-07-08 Abbott Laboratories Erythropoietin receptor binding antibodies
US20040178714A1 (en) * 2003-03-11 2004-09-16 Pan Wun Fang Decorative bulb of a series connected light string
US20060216757A1 (en) * 2003-04-25 2006-09-28 The Kenneth S. Warren Institute, Inc. Tissue protective cytokine receptor complex, assays for identifying tissue protective compounds and uses thereof
US7718363B2 (en) 2003-04-25 2010-05-18 The Kenneth S. Warren Institute, Inc. Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds
EP1670492A4 (en) * 2003-09-29 2009-07-08 Warren Pharmaceuticals Inc Tissue protective cytokines for the treatment and prevention of sepsis and the formation of adhesions
US20050255112A1 (en) * 2004-05-17 2005-11-17 Lee Jong Y Compositions and methods for preventing erythropoietin-associated hypertension
EP2321350A1 (en) * 2008-08-28 2011-05-18 F. Hoffmann-La Roche AG Antibodies against human epo receptor
CA2965031C (en) 2009-01-15 2018-12-04 F. Hoffmann-La Roche Ag Antibodies against phosphorylated tyrosines on erythropoietin receptor (epor)
JP5984919B2 (en) 2011-06-15 2016-09-06 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Anti-human EPO receptor antibody and method of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558005A (en) * 1982-09-13 1985-12-10 University Patents, Inc. Monoclonal anti-erythropoietin
WO1990008822A1 (en) * 1989-02-03 1990-08-09 Genetics Institute, Inc. Erythropoietin receptor

Also Published As

Publication number Publication date
KR960704052A (en) 1996-08-31
US20020031806A1 (en) 2002-03-14
EP0776370A4 (en) 2002-04-17
CA2169629C (en) 2002-06-11
DE69434704T2 (en) 2006-10-19
WO1995005469A1 (en) 1995-02-23
JPH09501833A (en) 1997-02-25
EP0776370A1 (en) 1997-06-04
EP0776370B1 (en) 2006-04-19
US5843726A (en) 1998-12-01
CA2169629A1 (en) 1995-02-23
DE69434704D1 (en) 2006-05-24
US7053184B2 (en) 2006-05-30

Similar Documents

Publication Publication Date Title
DE69638011D1 (en) ngriff
DE69636130D1 (en) Permeatsammelsystem
DK1419802T3 (en) Gelindkapslingsstruktur
DE69638219D1 (en) Teilchentrennverfahren
DE69635184T2 (en) Vielfachkapillarfluoreszenzsensoranordnung
DE69636827D1 (en) Spreizspektrumübertragungsgerät
DE69636741D1 (en) Bleichkatalysatorteilchen
DE69633991D1 (en) Kodemultiplexmehrfachzugriffsbasisstationssender
DE69836729D1 (en) Anti-vefg antibodies
DE69841514D1 (en) Human toll-like receptor proteins, associated reagents and methods
DE69636730D1 (en) Spreizspektrumübertragungssystem
DE69634097D1 (en) Einfürungsvorrichtung
DK0817797T3 (en) Glycopeptidantibiotikumderivater
DK1027439T3 (en) Multivalent antigen-binding proteins
DE69637794D1 (en) Sprühpistolekörper
DK1787999T3 (en) Anti-VEGF antibodies
DE69528111T2 (en) Biosensor and method of making the same
DE10199051I2 (en) Modified antibodies.
DE69737009D1 (en) Polymerized toner and process for its preparation
DE69634001D1 (en) Beleuchtungssystème
DE69434259D1 (en) Stentzuführvorrichtung and procedure
DE69635704D1 (en) Zahnfleischretraktionsvorrichtung
DE69629755D1 (en) Irbesartan-containing medicine
DK0942968T3 (en) Fully human antibodies that bind EGFR
DE69535419D1 (en) Antibodies that activate an erythropoietin receptor

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0776370

Country of ref document: EP

REN Ceased due to non-payment of the annual fee