AT321045T - Methods and compositions for treatment of pain - Google Patents

Methods and compositions for treatment of pain

Info

Publication number
AT321045T
AT321045T AT00987932T AT00987932T AT321045T AT 321045 T AT321045 T AT 321045T AT 00987932 T AT00987932 T AT 00987932T AT 00987932 T AT00987932 T AT 00987932T AT 321045 T AT321045 T AT 321045T
Authority
AT
Austria
Prior art keywords
pain
compositions
treatment
methods
Prior art date
Application number
AT00987932T
Other languages
German (de)
Inventor
Rebecca Ann Astrazenec Urbanek
Thomas Michael Bare
Dean Gordon Astrazeneca Brown
Wenhua Astrazeneca Xiao
Gary Banks Astrazenec Steelman
Megan Astrazeneca Murphy
Carey Lynn Astrazenec Horchler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US17190699P priority Critical
Priority to US23688100P priority
Application filed filed Critical
Publication of AT321045T publication Critical patent/AT321045T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/502Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/503Pyridazines; Hydrogenated pyridazines spiro-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
AT00987932T 1999-12-23 2000-12-19 Methods and compositions for treatment of pain AT321045T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US17190699P true 1999-12-23 1999-12-23
US23688100P true 2000-09-29 2000-09-29

Publications (1)

Publication Number Publication Date
AT321045T true AT321045T (en) 2006-04-15

Family

ID=26867561

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00987932T AT321045T (en) 1999-12-23 2000-12-19 Methods and compositions for treatment of pain

Country Status (7)

Country Link
US (1) US20030181449A1 (en)
EP (1) EP1244660B1 (en)
JP (1) JP2003519146A (en)
AT (1) AT321045T (en)
AU (1) AU2420001A (en)
DE (1) DE60026883T2 (en)
WO (1) WO2001047924A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004509962A (en) * 2000-09-29 2004-04-02 アストラゼネカ・アクチエボラーグ 1,2,5,10- tetrahydropyrido Da Gino [4,5-b] their use for the quinoline-1,10-dione and pain
JP2004509963A (en) * 2000-09-29 2004-04-02 アストラゼネカ・アクチエボラーグ 1,2,5,10- tetrahydropyrido Da Gino [4,5-b] their use for the quinoline-1,10-dione and pain
WO2002026741A1 (en) * 2000-09-29 2002-04-04 Astrazeneca Ab 1,2,5,10-TETRAHYDROPYRIDAZINO[4,5-b]QUINOLINE-1,10-DIONES AND THEIR USE FOR THE TREATMENT OF PAIN
EP2530075A3 (en) * 2004-06-24 2014-12-24 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
SE0403172D0 (en) * 2004-12-23 2004-12-23 Astrazeneca Ab Manufacturing process
LT1993360T (en) 2005-12-28 2017-06-12 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
MX361711B (en) 2009-03-20 2018-12-14 Vertex Pharmaceuticals Incorporated Star Process for making modulators of cystic fibrosis transmembrane conductance regulator.
CN109966264A (en) 2012-02-27 2019-07-05 沃泰克斯药物股份有限公司 Pharmaceutical composition and its application
WO2016057730A1 (en) 2014-10-07 2016-04-14 Strohmeier Mark Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
CA2892895A1 (en) * 2015-05-28 2016-11-28 Fluid Energy Group Ltd. Novel organic acid compositions for use in the oil and gas industry

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352683A (en) * 1993-03-05 1994-10-04 Virginia Commonwealth University Medical College Of Virginia Method for the treatment of chronic pain
GB9420590D0 (en) * 1993-10-22 1994-11-30 Zeneca Ltd Pyridazino quinoline compounds
GB9422894D0 (en) * 1994-11-12 1995-01-04 Zeneca Ltd Pyridazino quinoline compounds
US6787547B2 (en) * 1999-12-23 2004-09-07 Astrazeneca Ab Compound and method for the treatment of pain

Also Published As

Publication number Publication date
AU2420001A (en) 2001-07-09
US20030181449A1 (en) 2003-09-25
JP2003519146A (en) 2003-06-17
EP1244660A1 (en) 2002-10-02
EP1244660B1 (en) 2006-03-22
DE60026883D1 (en) 2006-05-11
WO2001047924A1 (en) 2001-07-05
DE60026883T2 (en) 2006-11-23

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties