AT307603T - A storage stable liquid compositions of glucagon-like peptide-1 - Google Patents

A storage stable liquid compositions of glucagon-like peptide-1

Info

Publication number
AT307603T
AT307603T AT99967463T AT99967463T AT307603T AT 307603 T AT307603 T AT 307603T AT 99967463 T AT99967463 T AT 99967463T AT 99967463 T AT99967463 T AT 99967463T AT 307603 T AT307603 T AT 307603T
Authority
AT
Austria
Prior art keywords
glucagon
peptide
liquid compositions
storage stable
stable liquid
Prior art date
Application number
AT99967463T
Other languages
German (de)
Inventor
Mark L Brader
Allen H Pekar
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US11349998P priority Critical
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to PCT/US1999/030395 priority patent/WO2000037098A1/en
Publication of AT307603T publication Critical patent/AT307603T/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
AT99967463T 1998-12-22 1999-12-21 A storage stable liquid compositions of glucagon-like peptide-1 AT307603T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11349998P true 1998-12-22 1998-12-22
PCT/US1999/030395 WO2000037098A1 (en) 1998-12-22 1999-12-21 Shelf-stable formulation of glucagon-like peptide-1

Publications (1)

Publication Number Publication Date
AT307603T true AT307603T (en) 2005-11-15

Family

ID=22349808

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99967463T AT307603T (en) 1998-12-22 1999-12-21 A storage stable liquid compositions of glucagon-like peptide-1

Country Status (9)

Country Link
EP (1) EP1140148B1 (en)
JP (1) JP4689833B2 (en)
AT (1) AT307603T (en)
AU (1) AU2373400A (en)
CA (1) CA2358107C (en)
DE (1) DE69928006T2 (en)
DK (1) DK1140148T3 (en)
ES (1) ES2249933T3 (en)
WO (1) WO2000037098A1 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
AT416784T (en) 2000-12-01 2008-12-15 Takeda Pharmaceutical A process for the preparation of a composition with a bioactive substance
ES2298378T3 (en) * 2001-06-28 2008-05-16 Novo Nordisk A/S Stable formulation of GLP-1 modified.
WO2003020201A2 (en) 2001-08-28 2003-03-13 Eli Lilly And Company Pre-mixes of glp-1 and basal insulin
WO2003035099A1 (en) 2001-10-19 2003-05-01 Eli Lilly And Company Biphasic mixtures of glp-1 and insulin
EP2261250B1 (en) 2001-12-21 2015-07-01 Human Genome Sciences, Inc. GCSF-Albumin fusion proteins
BRPI0408978B1 (en) 2003-04-08 2018-05-15 Novo Nordisk A/S Process for regenerating a chromatographic stationary phase
WO2004089985A1 (en) 2003-04-11 2004-10-21 Novo Nordisk A/S Stable pharmaceutical compositions
AT541582T (en) 2003-06-03 2012-02-15 Novo Nordisk As A stabilized pharmaceutical compositions of the GLP-1 peptide
CA2527743A1 (en) * 2003-06-03 2004-12-09 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
EP2292253A3 (en) * 2003-06-03 2011-12-14 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
WO2004105790A1 (en) 2003-06-03 2004-12-09 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
DK3300721T3 (en) 2003-11-20 2019-05-27 Novo Nordisk As Propylenglycol-containing peptid formulations which are optimal for manufacture and for use in injection devices
JP4965446B2 (en) 2004-08-31 2012-07-04 ノヴォ ノルディスク アー/エス Peptides, tris (hydroxymethyl) for the stabilization of polypeptides and proteins used in aminomethane
EP1814581B1 (en) * 2004-11-12 2016-03-16 Novo Nordisk A/S Stable formulations of peptides comprising an acylated glp-1 analogue and a basal insuline
DE602005016952D1 (en) 2004-10-21 2009-11-12 Novo Nordisk As A selector mechanism for a rotating pin
CN102772787A (en) * 2004-11-12 2012-11-14 诺和诺德公司 Stable formulations of insulinoptropic peptides
ES2612736T3 (en) 2007-11-16 2017-05-18 Novo Nordisk A/S Stable pharmaceutical compositions comprising liraglutide and degludec
WO2010076809A2 (en) * 2008-12-29 2010-07-08 Panacea Biotec Ltd Glp-1 analogs and uses thereof
US20120231022A1 (en) 2009-05-28 2012-09-13 Amylin Pharmaceuticals, Inc. Glp-1 receptor agonist compounds for sleep enhancement
EP2496249B1 (en) 2009-11-03 2016-03-09 Amylin Pharmaceuticals, LLC Glp-1 receptor agonist for use in treating obstructive sleep apnea
US9161953B2 (en) 2010-12-22 2015-10-20 Amylin Pharmaceuticals, Llc GLP-1 receptor agonists for islet cell transplantation
CA2861706A1 (en) 2011-12-29 2013-07-04 Novo Nordisk A/S Dial-up/dial-down mechanism for wind-up pen
US20150359864A1 (en) * 2012-03-09 2015-12-17 Oncotherapy Science, Inc. Pharmaceutical composition containing peptides
WO2014010586A1 (en) 2012-07-10 2014-01-16 武田薬品工業株式会社 Pharmaceutical preparation for injection
MX2015008077A (en) 2012-12-21 2015-10-30 Sanofi Sa Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists.
EP3080150B1 (en) 2013-12-13 2018-08-01 Sanofi Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
WO2015086729A1 (en) 2013-12-13 2015-06-18 Sanofi Dual glp-1/gip receptor agonists
TW201609796A (en) 2013-12-13 2016-03-16 Sanofi Sa Non-acylated EXENDIN-4 peptide analogues
WO2015086733A1 (en) 2013-12-13 2015-06-18 Sanofi Dual glp-1/glucagon receptor agonists
TW201625669A (en) 2014-04-07 2016-07-16 Sanofi Sa Peptidic dual GLP-1/glucagon receptor agonists derived from Exendin-4
TW201625668A (en) 2014-04-07 2016-07-16 Sanofi Sa Exendin-4 derivatives as peptidic dual GLP-1/glucagon receptor agonists
TW201625670A (en) 2014-04-07 2016-07-16 Sanofi Sa Dual GLP-1/glucagon receptor agonists derived from EXENDIN-4
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
AR105284A1 (en) 2015-07-10 2017-09-20 Sanofi Sa Exendin-4 derivatives as dual specific peptide agonists receptor glp-1 / glucagon
MX2018007859A (en) 2015-12-23 2018-11-09 Amgen Inc Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists.
WO2018237097A1 (en) 2017-06-20 2018-12-27 Amgen Inc. Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341320C (en) * 1986-05-05 2001-11-20 Joel Habener Insulinotropic hormone
US5118666A (en) * 1986-05-05 1992-06-02 The General Hospital Corporation Insulinotropic hormone
DK36492D0 (en) * 1992-03-19 1992-03-19 Novo Nordisk As Preparation
US5705483A (en) * 1993-12-09 1998-01-06 Eli Lilly And Company Glucagon-like insulinotropic peptides, compositions and methods
GB9409496D0 (en) * 1994-05-12 1994-06-29 London Health Ass Method for improving glycaemic control in diabetes
AU4298596A (en) * 1994-12-23 1996-07-19 Novo Nordisk A/S Protracted glp-1 compositions

Also Published As

Publication number Publication date
EP1140148B1 (en) 2005-10-26
JP2002532557A (en) 2002-10-02
ES2249933T3 (en) 2006-04-01
EP1140148A1 (en) 2001-10-10
CA2358107C (en) 2011-08-23
DE69928006T2 (en) 2006-07-13
WO2000037098A1 (en) 2000-06-29
JP4689833B2 (en) 2011-05-25
DE69928006D1 (en) 2005-12-01
AU2373400A (en) 2000-07-12
DK1140148T3 (en) 2006-01-30
CA2358107A1 (en) 2000-06-29

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