AT284433T - Fluorescent cyanine labels with a sulphamido bridge - Google Patents

Fluorescent cyanine labels with a sulphamido bridge

Info

Publication number
AT284433T
AT284433T AT99112696T AT99112696T AT284433T AT 284433 T AT284433 T AT 284433T AT 99112696 T AT99112696 T AT 99112696T AT 99112696 T AT99112696 T AT 99112696T AT 284433 T AT284433 T AT 284433T
Authority
AT
Austria
Prior art keywords
sulphamido
bridge
fluorescent cyanine
cyanine labels
labels
Prior art date
Application number
AT99112696T
Other languages
German (de)
Inventor
Giuseppe Caputo
Ciana Leopoldo Della
Original Assignee
Visen Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visen Medical Inc filed Critical Visen Medical Inc
Priority to EP19990112696 priority Critical patent/EP1065250B1/en
Publication of AT284433T publication Critical patent/AT284433T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
AT99112696T 1999-07-02 1999-07-02 Fluorescent cyanine labels with a sulphamido bridge AT284433T (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP19990112696 EP1065250B1 (en) 1999-07-02 1999-07-02 New fluorescent cyanine labels containing a sulfamido linker arm

Publications (1)

Publication Number Publication Date
AT284433T true AT284433T (en) 2004-12-15

Family

ID=8238492

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99112696T AT284433T (en) 1999-07-02 1999-07-02 Fluorescent cyanine labels with a sulphamido bridge
AT04023147T AT435262T (en) 1999-07-02 1999-07-02 Fluorescent cyanine labels with a sulphamidobrucor member

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT04023147T AT435262T (en) 1999-07-02 1999-07-02 Fluorescent cyanine labels with a sulphamidobrucor member

Country Status (8)

Country Link
US (1) US6448008B1 (en)
EP (2) EP1491591B1 (en)
AT (2) AT284433T (en)
AU (1) AU776841B2 (en)
BR (1) BR0005843A (en)
CA (1) CA2312099C (en)
DE (2) DE69941067D1 (en)
ES (1) ES2329572T3 (en)

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US7569695B2 (en) * 2005-05-24 2009-08-04 Enzo Life Sciences, Inc. Dyes for the detection or quantification of desirable target molecules
US8357801B2 (en) 2005-05-24 2013-01-22 Enzo Life Sciences, Inc. Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits
US7737281B2 (en) * 2005-05-24 2010-06-15 Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. Purine based fluorescent dyes
US8906354B2 (en) 2007-02-28 2014-12-09 Bruker Biospin Corporation Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes
US7947256B2 (en) 2005-09-02 2011-05-24 Visen Medical, Inc. Biocompatible fluorescent imaging agents
WO2007028118A2 (en) 2005-09-02 2007-03-08 Visen Medical, Inc. Nicotinic acid and picolinic acid derived near-infrared fluorophores
CA2621137C (en) * 2005-09-02 2014-07-29 Visen Medical, Inc. Biocompatible n,n-disubstituted sulfonamide-containing fluorescent dye labels
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EP1973575B1 (en) 2005-12-22 2019-07-24 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles
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JP2009524832A (en) 2006-01-24 2009-07-02 ライフ テクノロジーズ コーポレーション Device and method for quantifying analytes
WO2008029281A2 (en) 2006-02-10 2008-03-13 Invitrogen Corporation Labeling and detection of post translationally modified proteins
US8114636B2 (en) 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
US8562802B1 (en) 2006-02-13 2013-10-22 Life Technologies Corporation Transilluminator base and scanner for imaging fluorescent gels, charging devices and portable electrophoresis systems
SG171598A1 (en) 2006-03-23 2011-06-29 Absorber Ab Blood group antigens of different types for diagnostic and therapeutic applications
JP5337691B2 (en) 2006-04-20 2013-11-06 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company Thermostable protein and method for producing and using the same
EP2118206B9 (en) 2007-02-09 2018-08-29 Visen Medical, Inc. Polycyclo dyes and use thereof
US8017104B2 (en) 2007-02-28 2011-09-13 Carestream Health, Inc. Large stoke shift dye used for optical imaging
WO2008109832A2 (en) * 2007-03-08 2008-09-12 Visen Medical, Inc. Viable near-infrared fluorochrome labeled cells and methods of making and using same
CA2740602C (en) 2007-10-19 2017-05-02 Visen Medical, Inc. Imaging systems featuring waveguiding compensation
WO2009092062A2 (en) 2008-01-18 2009-07-23 Visen Medical, Inc. Fluorescent imaging agents
US20110118142A1 (en) 2008-05-16 2011-05-19 Life Technologies Corporation Dual labeling methods for measuring cellular proliferation
US8864821B2 (en) 2008-11-26 2014-10-21 Visen Medical, Inc. Methods and compositions for identifying subjects at risk of developing stent thrombosis
US9155471B2 (en) 2009-05-27 2015-10-13 Lumicell, Inc'. Methods and systems for spatially identifying abnormal cells
US20110021908A1 (en) 2009-05-27 2011-01-27 Lumicell Diagnostics, Inc. Methods and systems for spatially identifying abnormal cells
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US9314304B2 (en) 2010-12-08 2016-04-19 Lumicell, Inc. Methods and system for image guided cell ablation with microscopic resolution
EP2707102B1 (en) 2011-05-09 2019-11-13 Visen Medical, Inc. Carbonic anhydrase targeting agents and methods of using same
EP2831264B1 (en) 2012-03-30 2019-07-10 VisEn Medical, Inc. Bacterial imaging agents and methods of using same
EP2885006B1 (en) 2012-08-15 2018-08-08 VisEn Medical, Inc. Prostate specific antigen agents and methods of using same for prostate cancer imaging
EP2906106A1 (en) 2012-10-15 2015-08-19 VisEn Medical, Inc. Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources
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US9763577B2 (en) 2013-03-14 2017-09-19 Lumicell, Inc. Imaging agent for detection of diseased cells
WO2014144702A2 (en) 2013-03-15 2014-09-18 Visen Medical, Inc. 4,4-disubstituted cyclohexyl bridged heptamethine cyanine dyes and uses thereof
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KR20180087413A (en) * 2015-12-01 2018-08-01 디쉬맨 파마슈티컬스 앤드 케미컬스 리미티드 Method for manufacturing improved indocyanine green
AU2016374246A1 (en) 2015-12-15 2018-06-28 Cornell University Imaging systems and methods for tissue differentiation, e.g., for intraoperative visualization
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Also Published As

Publication number Publication date
AU776841B2 (en) 2004-09-23
AT435262T (en) 2009-07-15
BR0005843A (en) 2002-01-02
EP1065250A1 (en) 2001-01-03
DE69941067D1 (en) 2009-08-13
CA2312099C (en) 2009-05-12
EP1065250B1 (en) 2004-12-08
DE69922498D1 (en) 2005-01-13
CA2312099A1 (en) 2001-01-02
AU4258100A (en) 2001-01-11
US6448008B1 (en) 2002-09-10
EP1491591A1 (en) 2004-12-29
ES2329572T3 (en) 2009-11-27
DE69922498T2 (en) 2005-12-08
EP1491591B1 (en) 2009-07-01

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