AT278017T - Human k + ion channel and therapeutic uses thereof - Google Patents

Human k + ion channel and therapeutic uses thereof

Info

Publication number
AT278017T
AT278017T AT99920731T AT99920731T AT278017T AT 278017 T AT278017 T AT 278017T AT 99920731 T AT99920731 T AT 99920731T AT 99920731 T AT99920731 T AT 99920731T AT 278017 T AT278017 T AT 278017T
Authority
AT
Austria
Prior art keywords
human
ion channel
therapeutic uses
therapeutic
uses
Prior art date
Application number
AT99920731T
Other languages
German (de)
Inventor
Luis Angel Pardo-Fernandez
Walter Stuehmer
Synnoeve Beckh
Andrea Brueggemann
Camino Fernandez-Miranda D Del
School Medical
Perez Araceli Sanchez
Ruediger Weseloh
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP98107268 priority Critical
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Priority to PCT/EP1999/002695 priority patent/WO1999054463A2/en
Publication of AT278017T publication Critical patent/AT278017T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/315Phosphorothioates
AT99920731T 1998-04-21 1999-04-21 Human k + ion channel and therapeutic uses thereof AT278017T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP98107268 1998-04-21
PCT/EP1999/002695 WO1999054463A2 (en) 1998-04-21 1999-04-21 Human k+ ion channel and therapeutic applications thereof

Publications (1)

Publication Number Publication Date
AT278017T true AT278017T (en) 2004-10-15

Family

ID=8231794

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99920731T AT278017T (en) 1998-04-21 1999-04-21 Human k + ion channel and therapeutic uses thereof

Country Status (10)

Country Link
US (7) US6638736B1 (en)
EP (1) EP1073738B1 (en)
JP (2) JP2002512029A (en)
AT (1) AT278017T (en)
CA (1) CA2323571A1 (en)
DE (1) DE69920681T2 (en)
DK (1) DK1073738T3 (en)
ES (1) ES2230852T3 (en)
PT (1) PT1073738E (en)
WO (1) WO1999054463A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT278017T (en) * 1998-04-21 2004-10-15 Max Planck Gesellschaft Human k + ion channel and therapeutic uses thereof
DE10025620A1 (en) * 2000-05-24 2001-12-06 Forschungsgesellschaft Genion New nucleic acid encoding chimeric potassium channel protein, useful, when immobilized on carrier, in screening agents for toxicity and pharmaceutical activity
DE10224534A1 (en) * 2002-05-31 2003-12-11 Juergen Dolderer A method for diagnosing the colorektaien carcinoma in a tissue sample, and means for treating
DE602005026219D1 (en) * 2004-10-01 2011-03-17 Max Planck Gesellschaft Against the mammal-Eag1 ion channel protein antibodies directed
WO2006037611A2 (en) * 2004-10-01 2006-04-13 Centro De Investigación Y De Estudios Avanzados Del Ipn Methods for the early diagnosis of viral infections, inflammatory diseases, a predisposition for proliferative disorders or hyperplasia by analysing eag or erg expression levels
AU2013201604B2 (en) * 2007-04-13 2014-08-14 Southern Research Institute Anti-angiogenic agents and methods of use
ES2334084B1 (en) * 2007-12-21 2011-01-24 Inst Cientifico Tecnol Navarra Genetic markers for prognosis of multiple sclerosis.
US8892184B2 (en) 2010-10-18 2014-11-18 Siemens Medical Solutions Usa, Inc. Systems and methods for reducing interference in a dual modality imaging system
TWI570415B (en) * 2015-10-02 2017-02-11
EP3195727A1 (en) 2016-01-22 2017-07-26 Forschungsinstitut Fur Biologischen Landbau (FiBL) Duddingtonia flagrans strain and feed additive formulation for biological pest control

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394448A (en) * 1978-02-24 1983-07-19 Szoka Jr Francis C Method of inserting DNA into living cells
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
EP0563134B1 (en) 1990-12-18 1996-06-19 The Wellcome Foundation Limited Agents for potentiating the effects of antitumor agents and combating multiple drug resistance
GB9303210D0 (en) 1993-02-17 1993-03-31 Univ Manitoba Cancer treatment
EP0910410A1 (en) * 1996-07-02 1999-04-28 Novartis Consumer Health S.A. Topical composition comprising a combination of antihistaminic compounds with terpenoid compounds
US6610827B1 (en) * 1997-10-29 2003-08-26 Elan Pharmaceuticals, Inc. Potassium channel subunit polypeptide and polynucleotide compositions and uses therefor
AT278017T (en) * 1998-04-21 2004-10-15 Max Planck Gesellschaft Human k + ion channel and therapeutic uses thereof

Also Published As

Publication number Publication date
US7129207B2 (en) 2006-10-31
WO1999054463A2 (en) 1999-10-28
EP1073738B1 (en) 2004-09-29
US6638736B1 (en) 2003-10-28
WO1999054463A3 (en) 2000-04-20
ES2230852T3 (en) 2005-05-01
US20080020406A1 (en) 2008-01-24
US20100021467A1 (en) 2010-01-28
DE69920681T2 (en) 2005-09-08
JP2002512029A (en) 2002-04-23
US7364845B2 (en) 2008-04-29
PT1073738E (en) 2005-01-31
US20030087377A1 (en) 2003-05-08
US20030077735A1 (en) 2003-04-24
EP1073738A2 (en) 2001-02-07
US20030087378A1 (en) 2003-05-08
DK1073738T3 (en) 2005-01-24
DE69920681D1 (en) 2004-11-04
US7364730B2 (en) 2008-04-29
US7314914B2 (en) 2008-01-01
JP2009235091A (en) 2009-10-15
CA2323571A1 (en) 1999-10-28
US20030092120A1 (en) 2003-05-15

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