AT246244T - Recombinant cmv-neutralizing proteins - Google Patents

Recombinant cmv-neutralizing proteins

Info

Publication number
AT246244T
AT246244T AT93203533T AT93203533T AT246244T AT 246244 T AT246244 T AT 246244T AT 93203533 T AT93203533 T AT 93203533T AT 93203533 T AT93203533 T AT 93203533T AT 246244 T AT246244 T AT 246244T
Authority
AT
Austria
Prior art keywords
recombinant cmv
neutralizing proteins
neutralizing
proteins
cmv
Prior art date
Application number
AT93203533T
Other languages
German (de)
Inventor
Carol A Pachl
Richard R Spaete
Original Assignee
Aventis Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US14971588A priority Critical
Application filed by Aventis Pasteur filed Critical Aventis Pasteur
Publication of AT246244T publication Critical patent/AT246244T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/705Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/088Varicella-zoster virus, e.g. cytomegalovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA Viruses
    • C12N2710/00011MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA Viruses dsDNA Viruses
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
AT93203533T 1988-01-29 1989-01-26 Recombinant cmv-neutralizing proteins AT246244T (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US14971588A true 1988-01-29 1988-01-29

Publications (1)

Publication Number Publication Date
AT246244T true AT246244T (en) 2003-08-15

Family

ID=22531490

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93203533T AT246244T (en) 1988-01-29 1989-01-26 Recombinant cmv-neutralizing proteins

Country Status (10)

Country Link
US (2) US5834307A (en)
EP (2) EP0609580B1 (en)
JP (2) JP2607712B2 (en)
AT (1) AT246244T (en)
AU (1) AU641121B2 (en)
CA (1) CA1340832C (en)
DE (2) DE68929478T2 (en)
DK (1) DK176055B1 (en)
FI (1) FI109604B (en)
WO (1) WO1989007143A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
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US6100064A (en) * 1984-04-06 2000-08-08 Chiron Corporation Secreted viral proteins useful for vaccines and diagnostics
US6162620A (en) * 1986-03-07 2000-12-19 Cogent Limited Processes for the production of HCMV glycoproteins, antibodies thereto and HCMV vaccines, and recombinant vectors therefor
US5124440A (en) * 1986-11-24 1992-06-23 The Childrens Hospital, Inc. Antibody and T cell recognition sites on glycoproteins comprising the GCI complex of human cytomegalovirus
US5591439A (en) * 1989-03-24 1997-01-07 The Wistar Institute Of Anatomy And Biology Recombinant cytomegalovirus vaccine
US5552143A (en) * 1989-03-24 1996-09-03 The Wistar Institute Of Anatomy & Biology Recombinant cytomegalovirus vaccine
GB9008223D0 (en) * 1990-04-11 1990-06-13 Royal Free Hosp School Med Improvements relating to the detection of viruses
US5997878A (en) * 1991-03-07 1999-12-07 Connaught Laboratories Recombinant poxvirus-cytomegalovirus, compositions and uses
JPH07502655A (en) * 1991-12-23 1995-03-23
GB9409962D0 (en) * 1994-05-18 1994-07-06 Smithkline Beecham Biolog Novel compounds
HU9901005A2 (en) * 1995-09-26 1999-07-28 University Of Washington Herpes viruses derived from viruses of the RFHV / KSHV subfamily Glycoprotein B
WO1997040165A1 (en) * 1996-04-23 1997-10-30 The Wistar Institute Of Anatomy And Biology Novel human cytomegalovirus dna constructs and uses therefor
EP1137664A2 (en) * 1998-12-10 2001-10-04 Washington University Protein transduction system and methods of use thereof
US8206749B1 (en) 1999-02-26 2012-06-26 Novartis Vaccines And Diagnostics, Inc. Microemulsions with adsorbed macromolecules and microparticles
EP2248822B1 (en) 2001-07-27 2016-11-23 GlaxoSmithKline Biologicals SA Meningococcus adhesins
CA2508228C (en) 2002-12-23 2013-12-17 Vical Incorporated Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection
AR054822A1 (en) 2005-07-07 2007-07-18 Sanofi Pasteur Emulsion immuno adjuvant
WO2011005799A2 (en) 2009-07-06 2011-01-13 Novartis Ag Self replicating rna molecules and uses thereof
CA2779459A1 (en) 2009-10-30 2011-05-05 The Administrators Of The Tulane Educational Fund Peptide compositions and methods for inhibiting herpesvirus infection
SG181901A1 (en) 2009-12-23 2012-08-30 4Antibody Ag Binding members for human cytomegalovirus
BR112013000391A2 (en) 2010-07-06 2016-06-07 Novartis Ag cationic oil in water emulsions
EP2502631A1 (en) * 2011-03-22 2012-09-26 Medizinische Hochschule Hannover Immune suppressor and its use
CA2840965A1 (en) 2011-07-06 2013-01-10 Novartis Ag Cationic oil-in-water emulsions
EP2729125B1 (en) 2011-07-06 2017-12-13 GlaxoSmithKline Biologicals SA Oil-in-water emulsions that contain nucleic acids
CN104105504A (en) 2011-10-11 2014-10-15 诺华股份有限公司 Recombinant polycistronic RNA molecules
CN107875382A (en) 2011-11-11 2018-04-06 变异生物技术公司 Compositions and methods for treatment of cytomegalovirus
EP3077519A1 (en) * 2013-12-03 2016-10-12 Hookipa Biotech AG Cmv vaccines
CA3027877A1 (en) 2016-06-17 2017-12-21 Merial, Inc. Novel immunogenic formulations comprising linear or branched polyacrylic acid polymer adjuvants

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4313927A (en) * 1979-10-19 1982-02-02 Ames-Yissum Ltd. Immunoassay method for detecting viral antibodies in whole blood samples
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4460689A (en) * 1982-04-15 1984-07-17 Merck & Co., Inc. DNA Cloning vector TG1, derivatives, and processes of making
US5173402A (en) * 1982-11-02 1992-12-22 The Regents Of The University Of California Method and compositions for screening and diagnosing human cytomegalovirus ("hCMV")
US4762780A (en) * 1984-04-17 1988-08-09 The Regents Of The University Of California Method and composition for screening and diagnosing "HCMV"
US4783399A (en) 1984-05-04 1988-11-08 Scripps Clinic And Research Foundation Diagnostic system for the detection of cytomegalovirus
DE3585578D1 (en) * 1984-06-18 1992-04-16 Chiron Corp Hepatitisoberflaechenantigenpartikelvakzin.
US5075213A (en) * 1984-07-27 1991-12-24 City Of Hope Method for detection and prevention of human cytomegalovirus infection
US4689225A (en) * 1984-11-02 1987-08-25 Institut Merieux Vaccine for cytomegalovirus
EP0248909B1 (en) 1985-12-06 1994-08-17 Teijin Limited Anticytomegaloviral human monoclonal antibody and process for its preparation
CA1335429C (en) * 1986-03-07 1995-05-02 Geoffrey L. Smith Processes for the production of hcmv glycoproteins, antibodies thereto and hcmv vaccines, and recombinant vectors therefor
DE3619720A1 (en) * 1986-06-12 1987-12-17 Behringwerke Ag Major glycoprotein of human cytomegalovirus, its production and use
US5126130A (en) 1986-11-24 1992-06-30 The Childrens Hospital Incorporated Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a
US5124440A (en) * 1986-11-24 1992-06-23 The Childrens Hospital, Inc. Antibody and T cell recognition sites on glycoproteins comprising the GCI complex of human cytomegalovirus
US5403711A (en) * 1987-11-30 1995-04-04 University Of Iowa Research Foundation Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved
AU3550489A (en) * 1988-05-09 1989-11-29 Children's Hospital Incorporated, The Vectors encoding hcmv glycoprotein and expression products
US5262297A (en) * 1990-06-18 1993-11-16 Eastman Kodak Company Specific binding analytical and separation methods using carboxy containing polymers
JPH07502655A (en) * 1991-12-23 1995-03-23

Also Published As

Publication number Publication date
US5834307A (en) 1998-11-10
EP0609580B1 (en) 2003-07-30
DK179290D0 (en) 1990-07-27
FI903724A0 (en) 1990-07-25
AU641121B2 (en) 1993-09-16
WO1989007143A1 (en) 1989-08-10
CA1340832C (en) 1999-11-30
EP0436537A1 (en) 1991-07-17
FI109604B (en) 2002-09-13
JPH03503478A (en) 1991-08-08
DE68929478T2 (en) 2004-04-29
JP2607712B2 (en) 1997-05-07
DK179290A (en) 1990-09-28
EP0609580A1 (en) 1994-08-10
AU3041389A (en) 1989-08-25
FI903724D0 (en)
EP0436537A4 (en) 1992-04-08
US6190860B1 (en) 2001-02-20
DE68929478D1 (en) 2003-09-04
DK176055B1 (en) 2006-02-27
FI109604B1 (en)
JPH09176190A (en) 1997-07-08

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