AT235555T - Aspertokinasegenvarianten - Google Patents

Aspertokinasegenvarianten

Info

Publication number
AT235555T
AT235555T AT94902116T AT94902116T AT235555T AT 235555 T AT235555 T AT 235555T AT 94902116 T AT94902116 T AT 94902116T AT 94902116 T AT94902116 T AT 94902116T AT 235555 T AT235555 T AT 235555T
Authority
AT
Austria
Prior art keywords
aspertokinasegenvarianten
Prior art date
Application number
AT94902116T
Other languages
German (de)
Inventor
Masakazu Sugimoto
Yuri Ogawa
Tomoto Suzuki
Akiko Tanaka
Hiroshi Matsui
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP10145093A priority Critical patent/JP3473042B2/en
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Priority to PCT/JP1993/001809 priority patent/WO1994025605A1/en
Publication of AT235555T publication Critical patent/AT235555T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
AT94902116T 1992-04-28 1993-12-14 Aspertokinasegenvarianten AT235555T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP10145093A JP3473042B2 (en) 1992-04-28 1993-04-27 Mutant aspartokinase gene
PCT/JP1993/001809 WO1994025605A1 (en) 1993-04-27 1993-12-14 Variant aspartokinase gene

Publications (1)

Publication Number Publication Date
AT235555T true AT235555T (en) 2003-04-15

Family

ID=14301034

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94902116T AT235555T (en) 1992-04-28 1993-12-14 Aspertokinasegenvarianten

Country Status (8)

Country Link
US (1) US5688671A (en)
EP (1) EP0699759B1 (en)
JP (1) JP3473042B2 (en)
AT (1) AT235555T (en)
DE (2) DE69332805T2 (en)
DK (1) DK0699759T3 (en)
ES (1) ES2191680T3 (en)
WO (1) WO1994025605A1 (en)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696561B1 (en) 1909-07-09 2004-02-24 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
JP3473042B2 (en) * 1992-04-28 2003-12-02 味の素株式会社 Mutant aspartokinase gene
US5877179A (en) * 1992-09-29 1999-03-02 The United States Of America As Represented By The Department Of Health And Human Services Xanthines for identifying CFTR--binding compounds useful for activating chloride conductance in animal cells
CA2224058C (en) 1995-06-07 2011-09-13 Ajinomoto Co., Inc. Method of producing l-lysine
JP4035855B2 (en) 1996-06-05 2008-01-23 味の素株式会社 Method of producing L- lysine
SK285201B6 (en) * 1996-12-05 2006-08-03 Ajinomoto Co., Inc. Recombinant DNA autonomously replicable in cells of coryneform bacteria, coryneform bacterium and method for producing L-lysine, vector pVK7
JP4075087B2 (en) * 1996-12-05 2008-04-16 味の素株式会社 Method of producing L- lysine
CA2336967C (en) 1998-07-10 2010-06-29 The United States Of America, Represented By The Secretary, Department O F Health And Human Services A3 adenosine receptor antagonists
WO2000063388A1 (en) 1999-04-19 2000-10-26 Kyowa Hakko Kogyo Co., Ltd. Novel desensitized aspartokinase
US7270984B1 (en) 1999-06-25 2007-09-18 Basf Aktiengesellschaft Polynucleotides encoding a 6-phosphogluconolactonase polypeptide from corynebacterium glutamicum
JP2004534501A (en) 1999-06-25 2004-11-18 ビーエーエスエフ アクチェンゲゼルシャフト Corynebacterium encoding metabolic pathway proteins - glutamicum gene
DE1246922T1 (en) 1999-07-01 2003-03-20 Basf Ag For proteins of the phosphoenolpyruvate: sugar phosphotransferase system coding gene from corynebacterium glutamicum
US6884614B1 (en) 1999-07-01 2005-04-26 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins
AU781091B2 (en) 1999-07-02 2005-05-05 Ajinomoto Co., Inc. DNA encoding sucrose PTS enzyme II
US6797509B1 (en) 1999-07-09 2004-09-28 Degussa-Huls Ag Nucleotide sequences which code for the tal gene
HU0202613A2 (en) 1999-09-15 2002-12-28 Basf Plant Science Gmbh. Plants modified amino acid content and preparation method
JP2001120269A (en) * 1999-10-22 2001-05-08 Ajinomoto Co Inc Method for producing l-lysine by method for fermentation
EP1241246B1 (en) * 1999-12-24 2008-12-10 Ajinomoto Co., Inc. Process for producing l-amino acid
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
CA2397366C (en) 2000-01-14 2011-03-15 The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services Methanocarba cycloalkyl nucleoside analogues
DE10210527A1 (en) 2002-03-09 2003-09-18 Degussa Alleles of the aceA gene from coryneform bacteria
EP1976994A1 (en) * 2006-01-26 2008-10-08 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of enterobacteriaceae family with attenuated expression of the aldh gene
EP2004803A2 (en) * 2006-03-23 2008-12-24 Ajinomoto Co., Inc. A method for producing an l-amino acid using bacterium of theenterobacteriaceae family with attenuated expression of a gene coding for small rna
EP2386650B1 (en) * 2006-04-07 2013-07-03 Evonik Degussa GmbH Method for producing L-amino acids using the gap promoter
EP2007873B1 (en) * 2006-04-18 2015-11-18 Ajinomoto Co., Inc. A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE sfmACDFH-fimZ CLUSTER OR THE fimZ GENE
JP2009165355A (en) * 2006-04-28 2009-07-30 Ajinomoto Co Inc L-amino acid-producing microorganism and method for producing l-amino acid
EP2035569A1 (en) * 2006-06-01 2009-03-18 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family with attenuated expression of the rcsa gene
RU2337961C2 (en) * 2006-07-04 2008-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) METHOD OF OBTAINING L-THREONINE USING BACTERIUM, BELONGING TO GENUS Escherichia, IN WHICH OPERON rspAB IS INACTIVATED
EP1881076A1 (en) * 2006-07-17 2008-01-23 Evonik Degussa GmbH Method for producing L-amino acids
JP5407858B2 (en) * 2006-07-19 2014-02-05 味の素株式会社 Method for producing L-amino acid using bacteria of Enterobacteriaceae
JP2010017081A (en) 2006-10-10 2010-01-28 Ajinomoto Co Inc Method for producing l-amino acid
WO2008072761A2 (en) * 2006-12-11 2008-06-19 Ajinomoto Co., Inc. Method for producing an l-amino acid
RU2006143864A (en) * 2006-12-12 2008-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR PRODUCING L-AMINO ACIDS USING BACTERIA OF THE FAMILY ENTEROBACTERIACEAE, in which attenuates gene expression cynT, cynS, cynX, OR cynR, or combinations thereof
RU2006145712A (en) * 2006-12-22 2008-06-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) A process for preparing l-amino acids by fermentation using bacteria having enhanced ability to utilize glycerol
JP2010110217A (en) * 2007-02-22 2010-05-20 Ajinomoto Co Inc L-amino acid-producing microorganism and method for producing l-amino acid
JP5217780B2 (en) * 2008-02-08 2013-06-19 味の素株式会社 Microorganism producing L-amino acid and method for producing L-amino acid
WO2010005099A1 (en) 2008-07-09 2010-01-14 味の素株式会社 Method for producing aminohydroxybenzoic acid
JP2012029565A (en) 2008-11-27 2012-02-16 Ajinomoto Co Inc Method for producing l-amino acid
WO2011068978A1 (en) 2009-12-02 2011-06-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methanocarba adenosine derivatives and dendrimer conjugates thereof
EP2374873A1 (en) 2010-04-08 2011-10-12 Technische Universität Hamburg-Harburg Modified aspartate kinase from corynebacterium and its application for amino acid production
WO2013179711A1 (en) 2012-05-29 2013-12-05 味の素株式会社 Method for producing 3-acetylamino-4-hydroxybenzoic acid
DE102012016716A1 (en) 2012-08-22 2014-02-27 Forschungszentrum Jülich GmbH A process for the preparation of vectors comprising a gene coding for an enzyme which has been reduced or eliminated in its feedback inhibition and the use thereof for the production of amino acids and nucleotides
EP2940144A1 (en) 2014-04-30 2015-11-04 Evonik Degussa GmbH Method for the production of l-lysine using an alkaliphilic bacterium
EP2940039A1 (en) 2014-04-30 2015-11-04 Evonik Degussa GmbH Method for the production of l-amino acids in coryne bacteria using a glycine splitting system
EP2940143A1 (en) 2014-04-30 2015-11-04 Evonik Degussa GmbH Method for the production of l-amino acids using an alkaliphilic bacterium
DE102014208199A1 (en) 2014-04-30 2015-11-05 Evonik Degussa Gmbh Process for the production of L-amino acids using an alkaliphilic bacterium
KR102011994B1 (en) * 2017-06-30 2019-08-20 씨제이제일제당 주식회사 Novel aspartokinase variant and method of producing L-amino acid using thereof
EP3456833A1 (en) 2017-09-18 2019-03-20 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
EP3467099A1 (en) 2017-10-05 2019-04-10 Evonik Degussa GmbH Method for the fermentative production of l-amino acids
EP3498853A1 (en) 2017-12-14 2019-06-19 Evonik Degussa GmbH Method for the fermentative production of l-lysine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5763095A (en) * 1980-09-30 1982-04-16 Ajinomoto Co Inc Production of l-lysine through fermentation process
DE3908201A1 (en) * 1989-03-14 1990-09-27 Degussa Method for the fermentative manufacture of l-lysine
JP3473042B2 (en) * 1992-04-28 2003-12-02 味の素株式会社 Mutant aspartokinase gene
JPH06261766A (en) * 1993-03-16 1994-09-20 Mitsubishi Petrochem Co Ltd Genetic dna capable of coding aspartokinase released from feedback inhibition and its utilization

Also Published As

Publication number Publication date
JPH0662866A (en) 1994-03-08
EP0699759A4 (en) 1999-09-22
DK0699759T3 (en) 2003-09-15
DK699759T3 (en)
WO1994025605A1 (en) 1994-11-10
EP0699759A1 (en) 1996-03-06
DE69332805D1 (en) 2003-04-30
ES2191680T3 (en) 2003-09-16
DE69332805T2 (en) 2004-02-19
US5688671A (en) 1997-11-18
JP3473042B2 (en) 2003-12-02
EP0699759B1 (en) 2003-03-26

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