AT213630T - Use vonsisovaleramid as a mild anxiolytic and sedative agent - Google Patents

Use vonsisovaleramid as a mild anxiolytic and sedative agent

Info

Publication number
AT213630T
AT213630T AT94920093T AT94920093T AT213630T AT 213630 T AT213630 T AT 213630T AT 94920093 T AT94920093 T AT 94920093T AT 94920093 T AT94920093 T AT 94920093T AT 213630 T AT213630 T AT 213630T
Authority
AT
Austria
Prior art keywords
vonsisovaleramid
use
sedative agent
mild anxiolytic
anxiolytic
Prior art date
Application number
AT94920093T
Other languages
German (de)
Inventor
Manuel F Balandrin
Wagenen Bradford C Van
Original Assignee
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US08/075,126 priority Critical patent/US5506268A/en
Application filed by Nps Pharma Inc filed Critical Nps Pharma Inc
Priority to PCT/US1994/006356 priority patent/WO1994028888A1/en
Publication of AT213630T publication Critical patent/AT213630T/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/923Sleep aid
AT94920093T 1993-06-11 1994-06-10 Use vonsisovaleramid as a mild anxiolytic and sedative agent AT213630T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US08/075,126 US5506268A (en) 1993-06-11 1993-06-11 Use of isovaleramide as a mild anxiolytic and sedative agent
PCT/US1994/006356 WO1994028888A1 (en) 1993-06-11 1994-06-10 Use of isovaleramide as a mild anxiolytic and mild sedative agent

Publications (1)

Publication Number Publication Date
AT213630T true AT213630T (en) 2002-03-15

Family

ID=22123718

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94920093T AT213630T (en) 1993-06-11 1994-06-10 Use vonsisovaleramid as a mild anxiolytic and sedative agent

Country Status (14)

Country Link
US (2) US5506268A (en)
EP (1) EP0706385B1 (en)
JP (2) JP3790267B2 (en)
CN (1) CN1108793C (en)
AT (1) AT213630T (en)
CA (1) CA2164842C (en)
DE (2) DE69429990D1 (en)
DK (1) DK0706385T3 (en)
ES (1) ES2170770T3 (en)
IL (1) IL109982A (en)
PT (1) PT706385E (en)
RU (1) RU2136271C1 (en)
TW (1) TW420606B (en)
WO (1) WO1994028888A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4113984C2 (en) * 1991-04-29 2002-05-08 Koehler Chemie Dr Franz Salts of 4-hydroxy-butyric acid
US5786382A (en) * 1995-11-03 1998-07-28 Childers-Zadah; Vsande Use of valerian plant and/or root as a scent-attractant for stimulating canines and felines
US6589994B1 (en) * 1996-08-30 2003-07-08 Nps Pharmaceuticals, Inc. Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound
JP2000504035A (en) * 1996-08-30 2000-04-04 エヌピーエス パーマシューティカルズ インク. Spasticity due isovaleric cns inhibitors, treatment of convulsions
IL120006A (en) * 1997-01-14 2000-12-06 Yissum Res Dev Co Valnoctamide stereoisomers and a method for their synthesis and separation
NZ536524A (en) 1997-12-10 2006-04-28 Nps Pharma Inc Anticonvulsant and central nervous system-active bis(fluorophenyl)alkylamides
EP1576962A1 (en) * 1998-03-04 2005-09-21 Nps Pharmaceuticals, Inc. Composition comprising isovaleramide and ibuprofen
US6383527B1 (en) * 1999-03-04 2002-05-07 Nps Pharmaceuticals, Inc. Compositions comprising valerian extracts, isovaleric acid or derivatives thereof with a NSAID
AU2894599A (en) * 1998-03-04 1999-09-20 Nps Pharmaceuticals, Inc. Compositions comprising valerian extracts, isovaleric acid or derivatives thereof with a nsaid
US6346283B1 (en) * 1999-03-26 2002-02-12 Ancile Pharmaceuticals Use of valeriana for the treatment of restless leg syndrome and related disorders
US7235258B1 (en) 1999-10-19 2007-06-26 Nps Pharmaceuticals, Inc. Sustained-release formulations for treating CNS-mediated disorders
RU2209062C1 (en) * 2002-03-19 2003-07-27 Институт физиологии им. И.П.Павлова РАН Substance of sedative action
AU2003250106B2 (en) 2002-07-18 2009-11-26 Cytos Biotechnology Ag Hapten-carrier conjugates comprising virus like particles and uses thereof
WO2006012603A2 (en) * 2004-07-22 2006-02-02 Nps Pharmaceuticals, Inc. Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
US9212155B2 (en) 2008-03-19 2015-12-15 Aurimmed Pharma, Inc. Compounds advantageous in the treatment of central nervous system diseases and disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205083A (en) * 1968-03-30 1980-05-27 Kali-Chemie Aktiengesellschaft Cyclopentapyrans
US4246282A (en) * 1979-06-07 1981-01-20 Labaz ω-Dialkylalkanoic acid derivatives used to induce antianoxic activity
DE3026579A1 (en) * 1980-07-14 1982-02-11 Kali Chemie Pharma Gmbh 2,9-dioxatricyclo (4,3,1, o (arrow high) high) 3.7 (arrow) decanes
US4814183A (en) * 1987-08-31 1989-03-21 Merck & Co., Inc. Device for the controlled release of drugs with Donnan-like modulation by charged insoluble resins
DE4008403A1 (en) * 1990-03-16 1991-09-19 Merck Patent Gmbh Glykolsaeurederivate
FR2674524B1 (en) * 1991-03-25 1993-05-21 Adir New heterocyclic alkyl amide, their process for the preparation and pharmaceutical compositions containing them.

Also Published As

Publication number Publication date
DK706385T3 (en)
IL109982A (en) 1998-09-24
EP0706385A1 (en) 1996-04-17
EP0706385B1 (en) 2002-02-27
IL109982D0 (en) 1994-10-07
JP2006169259A (en) 2006-06-29
US5763494A (en) 1998-06-09
WO1994028888A1 (en) 1994-12-22
DE69429990D1 (en) 2002-04-04
CA2164842C (en) 2006-08-29
AU701360B2 (en) 1999-01-28
JPH09501908A (en) 1997-02-25
DK0706385T3 (en) 2002-04-29
CN1108793C (en) 2003-05-21
TW420606B (en) 2001-02-01
US5506268A (en) 1996-04-09
PT706385E (en) 2002-07-31
ES2170770T3 (en) 2002-08-16
AU7100694A (en) 1995-01-03
JP3790267B2 (en) 2006-06-28
CN1127472A (en) 1996-07-24
DE69429990T2 (en) 2002-09-05
CA2164842A1 (en) 1994-12-22
RU2136271C1 (en) 1999-09-10

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee