AT210983T - Stabilized combination product containing naloxone and an opiate analgesic - Google Patents

Stabilized combination product containing naloxone and an opiate analgesic

Info

Publication number
AT210983T
AT210983T AT98120639T AT98120639T AT210983T AT 210983 T AT210983 T AT 210983T AT 98120639 T AT98120639 T AT 98120639T AT 98120639 T AT98120639 T AT 98120639T AT 210983 T AT210983 T AT 210983T
Authority
AT
Austria
Prior art keywords
product containing
combination product
opiate analgesic
containing naloxone
stabilized combination
Prior art date
Application number
AT98120639T
Other languages
German (de)
Inventor
Peter Dr Hansen
Herbert Hofmann
Christof Schumann
Original Assignee
Stada Arzneimittel Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE29719483 priority Critical
Priority to DE29720448U priority patent/DE29720448U1/en
Priority to DE19833028 priority
Application filed by Stada Arzneimittel Ag filed Critical Stada Arzneimittel Ag
Publication of AT210983T publication Critical patent/AT210983T/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
AT98120639T 1997-11-03 1998-11-03 Stabilized combination product containing naloxone and an opiate analgesic AT210983T (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE29719483 1997-11-03
DE29720448U DE29720448U1 (en) 1997-11-03 1997-11-18 Stabilized combination drug
DE19833028 1998-07-23

Publications (1)

Publication Number Publication Date
AT210983T true AT210983T (en) 2002-01-15

Family

ID=27218535

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98120639T AT210983T (en) 1997-11-03 1998-11-03 Stabilized combination product containing naloxone and an opiate analgesic

Country Status (2)

Country Link
EP (1) EP0913152B1 (en)
AT (1) AT210983T (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
CA2314896C (en) 1997-12-22 2005-09-13 Euro-Celtique, S.A. A method of preventing abuse of opioid dosage forms
DK2266564T3 (en) 1997-12-22 2013-06-03 Euro Celtique Sa A pharmaceutical oral dosage form comprising a combination of an opioid agonist and an opioid antagonist
SI2092936T1 (en) 2000-02-08 2013-07-31 Euro-Celtique S.A. Tamper-resistant oral opioid agonist formulations
US6716449B2 (en) 2000-02-08 2004-04-06 Euro-Celtique S.A. Controlled-release compositions containing opioid agonist and antagonist
DE10059415A1 (en) * 2000-11-30 2002-06-06 Gruenenthal Gmbh Use of weak opioids and mixed opioid agonist / antagonist for the treatment of urinary incontinence
CA2446550C (en) 2001-05-11 2012-03-06 Endo Pharmaceuticals, Inc. Abuse-resistant controlled-release opioid dosage form
WO2003007802A2 (en) 2001-07-18 2003-01-30 Euro-Celtique, S.A. Pharmaceutical combinations of oxycodone and naloxone
US20030157168A1 (en) 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
EP1414451B1 (en) 2001-08-06 2009-05-20 Euro-Celtique S.A. Opioid agonist formulations with releasable and sequestered antagonist
TWI334779B (en) 2002-04-05 2010-12-21 Euro Celtique Sa Pharmaceutical preparation containing oxycodone and naloxone
EP2422775A3 (en) 2002-09-20 2012-04-18 Alpharma, Inc. Sequestering subunit and related compositions and methods
EP1615646B1 (en) 2003-04-08 2014-12-24 Progenics Pharmaceuticals, Inc. Pharmaceutical formulations containing methylnaltrexone
MY135852A (en) 2003-04-21 2008-07-31 Euro Celtique Sa Pharmaceutical products
EP1604666A1 (en) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
PL2484346T3 (en) 2006-06-19 2017-07-31 Alpharma Pharmaceuticals Llc Pharmaceutical compositions
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
WO2010103039A1 (en) 2009-03-10 2010-09-16 Euro-Celtique S.A. Immediate release pharmaceutical compositions comprising oxycodone and naloxone
PE00632013A1 (en) 2010-03-11 2013-02-11 Wyeth Llc Oral Formulations and salts lipophilic methylnaltrexone
CN103002881B (en) 2010-05-10 2015-09-02 欧洲凯尔特公司 Compositions containing the active agent particles and the additional active agent
BR112012028788A2 (en) 2010-05-10 2016-07-19 Euro Celtique Sa manufacturing granules without active
CA2881144A1 (en) * 2012-11-09 2014-05-09 Purdue Pharma Pharmaceutical compositions comprising hydromorphone and naloxone
US20140271788A1 (en) 2013-03-15 2014-09-18 Monosol Rx, Llc Sublingual and buccal film compositions
JP2016525138A (en) 2013-07-23 2016-08-22 ユーロ−セルティーク エス.エイ. The combination of oxycodone and naloxone for use in the treatment of pain in patients suffering from diseases increase the risk for diseases and / or Enterobacteriaceae migration results in pain and intestinal Disconnect bio cis
EA030310B1 (en) 2013-11-13 2018-07-31 Эро-Селтик С.А. Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8332556D0 (en) * 1983-12-06 1984-01-11 Reckitt & Colmann Prod Ltd Analgesic compositions
SK281041B6 (en) * 1992-10-26 2000-11-07 Gödecke Aktiengesellschaft Tilidin dihydrogen orthophosphate, process for preparing it, use thereof, and pharmaceutical preparations containing it
JPH07304673A (en) * 1994-05-09 1995-11-21 Sekisui Chem Co Ltd Percutaneously absorbable cataplasm
DE4423850A1 (en) * 1994-07-07 1996-01-11 Labtec Gmbh Transdermal delivery device for naloxone hydrochloride
AU6657396A (en) * 1995-07-28 1997-02-26 Novartis Ag Transdermal system
WO1998035679A1 (en) * 1997-02-14 1998-08-20 Gödecke Aktiengesellschaft Stabilization of naloxonhydrochlorid

Also Published As

Publication number Publication date
EP0913152A1 (en) 1999-05-06
EP0913152B1 (en) 2001-12-19

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