AT208395T - Thiophenopyrimidine - Google Patents

Thiophenopyrimidine

Info

Publication number
AT208395T
AT208395T AT97904368T AT97904368T AT208395T AT 208395 T AT208395 T AT 208395T AT 97904368 T AT97904368 T AT 97904368T AT 97904368 T AT97904368 T AT 97904368T AT 208395 T AT208395 T AT 208395T
Authority
AT
Austria
Prior art keywords
thiophenopyrimidine
Prior art date
Application number
AT97904368T
Other languages
English (en)
Inventor
Chen Chen
Thomas R Webb
James R Mccarthy
Terence J Moran
Original Assignee
Janssen Pharmaceutica Nv
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US1127496P priority Critical
Priority to US2768996P priority
Application filed by Janssen Pharmaceutica Nv, Neurocrine Biosciences Inc filed Critical Janssen Pharmaceutica Nv
Priority to PCT/EP1997/000457 priority patent/WO1997029110A1/en
Publication of AT208395T publication Critical patent/AT208395T/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
AT97904368T 1996-02-07 1997-01-30 Thiophenopyrimidine AT208395T (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US1127496P true 1996-02-07 1996-02-07
US2768996P true 1996-10-08 1996-10-08
PCT/EP1997/000457 WO1997029110A1 (en) 1996-02-07 1997-01-30 Thiophenopyrimidines

Publications (1)

Publication Number Publication Date
AT208395T true AT208395T (de) 2001-11-15

Family

ID=26682201

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97904368T AT208395T (de) 1996-02-07 1997-01-30 Thiophenopyrimidine

Country Status (17)

Country Link
US (2) US6255310B1 (de)
EP (1) EP0882051B1 (de)
JP (1) JP2000504678A (de)
KR (1) KR19990067390A (de)
AR (1) AR005731A1 (de)
AT (1) AT208395T (de)
CA (1) CA2233307A1 (de)
DE (1) DE69708059T2 (de)
DK (1) DK0882051T3 (de)
ES (1) ES2167710T3 (de)
ID (1) ID15904A (de)
MY (1) MY119118A (de)
NO (1) NO981356L (de)
NZ (1) NZ330118A (de)
PT (1) PT882051E (de)
TW (1) TW448178B (de)
WO (1) WO1997029110A1 (de)

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US6191131B1 (en) 1997-07-23 2001-02-20 Dupont Pharmaceuticals Company Azolo triazines and pyrimidines
US6060478A (en) * 1996-07-24 2000-05-09 Dupont Pharmaceuticals Azolo triazines and pyrimidines
US6124289A (en) * 1996-07-24 2000-09-26 Dupont Pharmaceuticals Co. Azolo triazines and pyrimidines
US7094782B1 (en) 1996-07-24 2006-08-22 Bristol-Myers Squibb Company Azolo triazines and pyrimidines
US6313124B1 (en) 1997-07-23 2001-11-06 Dupont Pharmaceuticals Company Tetrazine bicyclic compounds
EA005889B1 (ru) 1997-11-11 2005-06-30 Пфайзер Продактс Инк. Производные тиенопиримидина и тиенопиридина, полезные в качестве противораковых агентов
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
DE19837387A1 (de) * 1998-08-18 2000-02-24 Aventis Res & Tech Gmbh & Co 3'-Desoxypentopyranosyl-Nucleinsäure, ihre Herstellung und Verwendung
US6432989B1 (en) 1999-08-27 2002-08-13 Pfizer Inc Use of CRF antagonists to treat circadian rhythm disorders
EA200200424A1 (ru) 1999-09-30 2002-12-26 Ньюроджен Корпорейшн Некоторые гетероциклы, замещенные алкилендиамином
IL139197D0 (en) * 1999-10-29 2001-11-25 Pfizer Prod Inc Use of corticotropin releasing factor antagonists and related compositions
TWI271406B (en) 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
ES2223827T3 (es) 2000-06-06 2005-03-01 Pfizer Products Inc. Derivados de tiofeno utiles como agentes anticancerigenos.
US6503914B1 (en) 2000-10-23 2003-01-07 Board Of Regents, The University Of Texas System Thienopyrimidine-based inhibitors of the Src family
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
EP1389618B1 (de) 2001-04-27 2011-06-15 Eisai R&D Management Co., Ltd. Pyrazolo 1,5-a pyridine und diese enthaltende arzneimittel
US7285557B2 (en) * 2001-10-15 2007-10-23 Smithkline Beecham P.L.C. Pyrimidinones as melanin concentrating hormone receptor 1
US6872827B2 (en) 2002-04-26 2005-03-29 Chembridge Research Laboratories, Inc. Somatostatin analogue compounds
US20100189797A1 (en) 2002-06-10 2010-07-29 Julien Mendlewicz Oral antidepressant formulation
US7671047B2 (en) * 2002-06-19 2010-03-02 Sanofi-Aventis Deutschland Gmbh Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
SI1555265T1 (sl) 2002-10-22 2009-06-30 Eisai R&D Man Co Ltd 7-fenil pirazolopiridinske spojine
US7176216B2 (en) 2002-10-22 2007-02-13 Eisai Co., Ltd. 7-phenylpyrazolopyridine compounds
US20050001673A1 (en) * 2002-10-29 2005-01-06 Zvi Regev Direct digital frequency modulation / phase modulation decoder
US20060071832A1 (en) * 2002-10-29 2006-04-06 Zvi Regev Instantaneous phase digitizer
US20060024661A1 (en) * 2003-07-30 2006-02-02 The Regents Of The University Of California Modulation of CRF potentiation of NMDA receptor currents via CRF receptor 2
CN1910190A (zh) * 2004-01-06 2007-02-07 大正制药株式会社 环氨基取代的噻吩并嘧啶和噻吩并吡啶衍生物
RU2367663C2 (ru) 2004-01-06 2009-09-20 Тайсо Фармасьютикал Ко., Лтд. Производные пирролопиримидина и пирролотриазина
BRPI0509201A (pt) 2004-03-23 2007-08-28 Biogen Idec Inc agentes de acoplamento de receptor e usos terapêuticos destes
US20090081243A1 (en) 2004-06-03 2009-03-26 Athlomics Pty Ltd. Agents and methods for diagnosing stress
JP2007161585A (ja) 2004-06-25 2007-06-28 Taisho Pharmaceut Co Ltd 環状アミノ基で置換されているピロロピリミジン及びピロロピリジン誘導体
CA2602533A1 (en) 2005-03-29 2006-10-05 Biocryst Pharmaceuticals, Inc. Use of c-nucleoside analogs for treatment of hepatitis c related viral infections
KR20070100237A (ko) 2004-10-29 2007-10-10 바이오크리스트 파마수티컬즈, 인코퍼레이티드 치료용 푸로피리미딘 및 티에노피리미딘
WO2008082839A2 (en) * 2006-12-29 2008-07-10 Abbott Laboratories Pim kinase inhibitors as cancer chemotherapeutics
JP4654325B2 (ja) 2008-04-15 2011-03-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 3−フェニルピラゾロ[5,1−b]チアゾール化合物
AR078521A1 (es) 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
EP3394056B1 (de) 2015-12-22 2021-04-14 Shy Therapeutics LLC Verbindungen zur behandlung von krebs und entzündungskrankheiten
SG11201911929XA (en) 2017-06-21 2020-01-30 SHY Therapeutics LLC Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
CN110590807A (zh) * 2019-10-09 2019-12-20 陕西理工大学 一种新型噻吩并[3,2-d]嘧啶类衍生物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2121950A1 (en) 1971-05-04 1972-11-23 Dr. Karl Thomae Gmbh, 7950 Biberach Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE3277623D1 (en) * 1981-07-31 1987-12-17 Sloan Kettering Inst Cancer Anti-leukemic beta-glycosyl c-nucleosides
US5063245A (en) * 1990-03-28 1991-11-05 Nova Pharmaceutical Corporation Corticotropin-releasing factor antagonism compounds
BR9101256A (pt) * 1990-03-30 1991-11-05 Dowelanco Composto,composicao fungicida,processo fungicida,composicao inseticida ou acaricida e processo inseticida ou acaricida
TW444018B (en) * 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
ES2128544T3 (es) * 1992-12-17 1999-05-16 Pfizer Pirrolopirimidinas como antagonistas del crf.
TW574214B (en) 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
KR100256707B1 (ko) 1995-05-12 2000-05-15 해피 페너 데아자푸린 유도체; 새로운 부류의 crf1 특이 리간드

Also Published As

Publication number Publication date
NO981356D0 (no) 1998-03-25
EP0882051B1 (de) 2001-11-07
CA2233307A1 (en) 1997-08-14
US20020052362A1 (en) 2002-05-02
US6469166B2 (en) 2002-10-22
DK882051T3 (de)
ID15904A (id) 1997-08-14
TW448178B (en) 2001-08-01
AR005731A1 (es) 1999-07-14
AU1720997A (en) 1997-08-28
WO1997029110A1 (en) 1997-08-14
NO981356L (no) 1998-07-09
DK0882051T3 (da) 2002-02-25
ES2167710T3 (es) 2002-05-16
AU725674B2 (en) 2000-10-19
MY119118A (en) 2005-03-31
NZ330118A (en) 2000-03-27
DE69708059D1 (en) 2001-12-13
KR19990067390A (ko) 1999-08-16
JP2000504678A (ja) 2000-04-18
US6255310B1 (en) 2001-07-03
EP0882051A1 (de) 1998-12-09
PT882051E (pt) 2002-04-29
DE69708059T2 (de) 2002-07-18

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Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee