AT207919T - Quinidine conjugates and their application in immunoassays - Google Patents

Quinidine conjugates and their application in immunoassays

Info

Publication number
AT207919T
AT207919T AT96927300T AT96927300T AT207919T AT 207919 T AT207919 T AT 207919T AT 96927300 T AT96927300 T AT 96927300T AT 96927300 T AT96927300 T AT 96927300T AT 207919 T AT207919 T AT 207919T
Authority
AT
Austria
Prior art keywords
quinidine
immunoassays
conjugates
application
Prior art date
Application number
AT96927300T
Other languages
German (de)
Inventor
Donald Max Simons
Original Assignee
Dade Behring Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US51088695A priority Critical
Application filed by Dade Behring Inc filed Critical Dade Behring Inc
Priority to PCT/US1996/012649 priority patent/WO1997006166A1/en
Publication of AT207919T publication Critical patent/AT207919T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9453Cardioregulators, e.g. antihypotensives, antiarrhythmics
AT96927300T 1995-08-03 1996-08-02 Quinidine conjugates and their application in immunoassays AT207919T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US51088695A true 1995-08-03 1995-08-03
PCT/US1996/012649 WO1997006166A1 (en) 1995-08-03 1996-08-02 Quinidine conjugates and their use in immunoassays

Publications (1)

Publication Number Publication Date
AT207919T true AT207919T (en) 2001-11-15

Family

ID=24032598

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96927300T AT207919T (en) 1995-08-03 1996-08-02 Quinidine conjugates and their application in immunoassays

Country Status (8)

Country Link
US (1) US6140530A (en)
EP (2) EP1125935A3 (en)
JP (1) JPH10509984A (en)
CN (1) CN1166172A (en)
AT (1) AT207919T (en)
DE (2) DE69616493D1 (en)
ES (1) ES2163648T3 (en)
WO (1) WO1997006166A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890765B2 (en) * 2001-11-02 2005-05-10 Roche Diagnostics Operations, Inc. Particles for immunoassays and methods for treating the same
US6777246B2 (en) 2001-12-18 2004-08-17 Roche Diagnostics Gmbh Tertiary amine compounds for use in immunoassays
TWI326214B (en) * 2002-07-17 2010-06-21 Avanir Pharmaceuticals Inc Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
JP6226958B2 (en) * 2012-04-18 2017-11-08 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. Compounds and methods for preparing the conjugate reagent

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341865A (en) * 1980-07-21 1982-07-27 Abbott Laboratories Determination of thyroxine binding globulin
WO1985000605A1 (en) * 1983-07-27 1985-02-14 American Hospital Supply Corporation Process for selective nitrile reduction
US4582789A (en) * 1984-03-21 1986-04-15 Cetus Corporation Process for labeling nucleic acids using psoralen derivatives
US4617261A (en) * 1984-03-21 1986-10-14 Cetus Corporation Process for labeling nucleic acids and hybridization probes
US4952569A (en) * 1985-12-02 1990-08-28 E. I. Du Pont De Nemours And Company Estriol derivatives
US4822731A (en) * 1986-01-09 1989-04-18 Cetus Corporation Process for labeling single-stranded nucleic acids and hybridizaiton probes
US5260461A (en) * 1988-01-11 1993-11-09 Massachusetts Institute Of Technology Ligands for ADH: cinchona alkaloids and moderately sized organic substituents linked through a planar aromatic spacer group
US5126494A (en) * 1988-01-11 1992-06-30 Massachusetts Institute Of Technology Methods for catalytic asymmetric dihydroxylation of olefins
CA2049359A1 (en) * 1989-03-28 1990-09-29 Leslie A. Freiberg Erythromycin derivatives
ES2282988T3 (en) * 1993-09-08 2007-10-16 La Jolla Pharmaceutical Company Valency platform molecules nonpolymeric ,.
US5288749A (en) * 1991-12-20 1994-02-22 Abbott Laboratories Tertiary and secondary amines as alpha-2 antagonists and serotonin uptake inhibitors
DE4219159A1 (en) * 1992-06-11 1993-12-16 Boehringer Mannheim Gmbh Self assembling monolayer with short-chain linkers
DE4239815A1 (en) * 1992-11-26 1994-06-01 Boehringer Mannheim Gmbh Improved B¶1¶¶2¶ conjugates
US5492841A (en) * 1994-02-18 1996-02-20 E. I. Du Pont De Nemours And Company Quaternary ammonium immunogenic conjugates and immunoassay reagents

Also Published As

Publication number Publication date
CN1166172A (en) 1997-11-26
EP1125935A3 (en) 2001-12-12
JPH10509984A (en) 1998-09-29
EP1125935A2 (en) 2001-08-22
EP0784621B1 (en) 2001-10-31
WO1997006166A1 (en) 1997-02-20
ES2163648T3 (en) 2002-02-01
DE69616493T2 (en) 2002-06-27
DE69616493D1 (en) 2001-12-06
EP0784621A1 (en) 1997-07-23
US6140530A (en) 2000-10-31

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties