AT192498T - Vector for integration provide independent gene expression in mammalian host cells - Google Patents

Vector for integration provide independent gene expression in mammalian host cells

Info

Publication number
AT192498T
AT192498T AT90903867T AT90903867T AT192498T AT 192498 T AT192498 T AT 192498T AT 90903867 T AT90903867 T AT 90903867T AT 90903867 T AT90903867 T AT 90903867T AT 192498 T AT192498 T AT 192498T
Authority
AT
Austria
Prior art keywords
vector
gene expression
host cells
mammalian host
provide independent
Prior art date
Application number
AT90903867T
Other languages
German (de)
Inventor
Sarah Jane Eccles
Franklin Gerardus Grosveld
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB898904009A priority Critical patent/GB8904009D0/en
Application filed by Medical Res Council filed Critical Medical Res Council
Priority to PCT/GB1990/000286 priority patent/WO1990010077A1/en
Publication of AT192498T publication Critical patent/AT192498T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
AT90903867T 1989-02-22 1990-02-22 Vector for integration provide independent gene expression in mammalian host cells AT192498T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB898904009A GB8904009D0 (en) 1989-02-22 1989-02-22 Vector
PCT/GB1990/000286 WO1990010077A1 (en) 1989-02-22 1990-02-22 Vector for integration site independent gene expression in mammalian host cells

Publications (1)

Publication Number Publication Date
AT192498T true AT192498T (en) 2000-05-15

Family

ID=10652102

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90903867T AT192498T (en) 1989-02-22 1990-02-22 Vector for integration provide independent gene expression in mammalian host cells

Country Status (10)

Country Link
EP (2) EP0460042B1 (en)
JP (1) JPH04505552A (en)
AT (1) AT192498T (en)
AU (2) AU5161490A (en)
CA (2) CA2050920A1 (en)
DE (2) DE69033531T2 (en)
DK (1) DK0460042T3 (en)
ES (1) ES2150411T3 (en)
GB (1) GB8904009D0 (en)
WO (1) WO1990010077A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9027917D0 (en) * 1990-12-21 1991-02-13 Ici Plc Expression systems
DE4228162C1 (en) 1992-08-25 1994-01-13 Rajewsky Klaus Dr A method of replacing homologous gene segments from the germ line of mammals in non-human mammals
DE19541450C2 (en) * 1995-11-07 1997-10-02 Gsf Forschungszentrum Umwelt Gene construct and use thereof
AT399541T (en) 1998-08-18 2008-07-15 Univ California Epidermal growth factor receptor antagonists for the treatment greatly increased mucus secretion in the lungs
EP2308974A3 (en) 1999-10-14 2011-08-10 Clontech Laboratories Inc. Anthozoa derived chromo/fluoroproteins and methods for using the same
JP2003000243A (en) 2001-06-25 2003-01-07 Takachika Azuma Method for producing mutant
AT439368T (en) 2001-12-19 2009-08-15 Univ Chicago Quick Ripening fluorescent proteins and methods for their application
US7585501B2 (en) 2002-06-14 2009-09-08 Stowers Institute For Medical Research Compositions and methods for treating kidney disease
US20070172446A1 (en) 2003-05-16 2007-07-26 Intermune, Inc. Synthetic chemokine receptor ligands and methods of use thereof
EA011857B8 (en) 2003-10-14 2012-08-30 Интермьюн, Инк. Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
JP4755174B2 (en) 2004-04-07 2011-08-24 ザ ユニヴァーシティ オヴ ワシントン Monomeric red fluorescent protein
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
EP2029157A4 (en) 2006-05-19 2009-11-18 Georgia Tech Res Inst Abc transporter ligand
WO2008008873A2 (en) 2006-07-14 2008-01-17 Georgia Tech Research Corporation Clc channel ligand
WO2008094316A2 (en) 2006-09-22 2008-08-07 Stowers Institute Of Medical Research Novel branchiostoma derived fluorescent proteins
US8679749B2 (en) 2007-11-01 2014-03-25 The University Of Chicago Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation
EP2341924A4 (en) 2008-10-02 2013-01-23 David Gladstone Inst Methods of treating hepatitis c virus infection
CN102292445A (en) 2008-12-18 2011-12-21 伊拉兹马斯大学鹿特丹医学中心 Express humanized antibodies and nonhuman transgenic animal use
CN104826106B (en) 2009-09-30 2019-01-11 斯隆凯特林防癌纪念中心 Combination immunotherapy for treating cancer
WO2014141189A1 (en) 2013-03-14 2014-09-18 Erasmus University Medical Center Transgenic non-human mammal for antibody production

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988005083A1 (en) * 1986-12-24 1988-07-14 Whitehead Institute For Biomedical Research Method of inducible gene expression
DE3724482C2 (en) * 1987-07-24 1995-12-14 Boehringer Mannheim Gmbh A process for the expansion of the cell specificity of eukaryotic expression vectors

Also Published As

Publication number Publication date
AU672910B2 (en) 1996-10-17
ES2150411T3 (en) 2000-12-01
DE69033531T2 (en) 2001-01-11
CA2297385A1 (en) 1990-08-23
DE69033531D1 (en) 2000-06-08
JPH04505552A (en) 1992-10-01
EP0460042B1 (en) 2000-05-03
CA2050920A1 (en) 1990-08-23
EP0962534A2 (en) 1999-12-08
AU6872694A (en) 1994-11-17
EP0460042A1 (en) 1991-12-11
EP0962534A3 (en) 1999-12-22
DK0460042T3 (en) 2000-07-31
AU5161490A (en) 1990-09-26
GB8904009D0 (en) 1989-04-05
WO1990010077A1 (en) 1990-09-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee