AT177531T - n Hochleistungsflüssigkeitschromatographieverfahr and apparatus - Google Patents

n Hochleistungsflüssigkeitschromatographieverfahr and apparatus

Info

Publication number
AT177531T
AT177531T AT96938675T AT96938675T AT177531T AT 177531 T AT177531 T AT 177531T AT 96938675 T AT96938675 T AT 96938675T AT 96938675 T AT96938675 T AT 96938675T AT 177531 T AT177531 T AT 177531T
Authority
AT
Austria
Prior art keywords
hochleistungsflüssigkeitschromatographieverfahr
apparatus
Prior art date
Application number
AT96938675T
Other languages
German (de)
Inventor
Hubert M Quinn
Joseph J Takarewski Jr
Original Assignee
Cohesive Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US55219395A priority Critical
Priority to US08/661,367 priority patent/US5772874A/en
Application filed by Cohesive Tech Inc filed Critical Cohesive Tech Inc
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27069969&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT177531(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of AT177531T publication Critical patent/AT177531T/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/48Sorbent materials therefor
    • G01N30/482Solid sorbents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/14Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004Sorbent size or size distribution, e.g. particle size
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016Particle form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078Pore diameter
    • B01J20/28083Pore diameter being in the range 2-50 nm, i.e. mesopores
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078Pore diameter
    • B01J20/28085Pore diameter being more than 50 nm, i.e. macropores
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/283Porous sorbents based on silica
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/284Porous sorbents based on alumina
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/32Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/324Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N2030/387Turbulent flow of mobile phase
AT96938675T 1995-11-02 1996-11-01 n Hochleistungsflüssigkeitschromatographieverfahr and apparatus AT177531T (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US55219395A true 1995-11-02 1995-11-02
US08/661,367 US5772874A (en) 1995-11-02 1996-06-11 High performance liquid chromatography method and apparatus

Publications (1)

Publication Number Publication Date
AT177531T true AT177531T (en) 1999-03-15

Family

ID=27069969

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96938675T AT177531T (en) 1995-11-02 1996-11-01 n Hochleistungsflüssigkeitschromatographieverfahr and apparatus

Country Status (13)

Country Link
US (2) US5772874A (en)
EP (1) EP0838032B1 (en)
JP (1) JP3354155B2 (en)
AT (1) AT177531T (en)
AU (1) AU706707B2 (en)
CA (1) CA2236712C (en)
DE (2) DE69601722T2 (en)
DK (1) DK0838032T3 (en)
ES (1) ES2130857T3 (en)
NZ (1) NZ322280A (en)
PL (1) PL326484A1 (en)
TW (1) TW518246B (en)
WO (1) WO1997016724A2 (en)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL327920A1 (en) * 1996-01-19 1999-01-04 Cohesive Technologies Highly efficient liquid chromatography process and chromatographic apparatus therefor
US6063633A (en) 1996-02-28 2000-05-16 The University Of Houston Catalyst testing process and apparatus
US6110362A (en) * 1997-11-19 2000-08-29 Cohesive Technologies, Inc. Chemical analysis
US6296771B1 (en) 1999-04-02 2001-10-02 Symyx Technologies, Inc. Parallel high-performance liquid chromatography with serial injection
US6416663B1 (en) 1998-04-03 2002-07-09 Symyx Technologies, Inc. Chromatographic column for rapid characterizations of polymers
US6720186B1 (en) * 1998-04-03 2004-04-13 Symyx Technologies, Inc. Method of research for creating and testing novel catalysts, reactions and polymers
US6866786B2 (en) * 1998-04-03 2005-03-15 Symyx Technologies, Inc. Rapid characterization of polymers
US6406632B1 (en) 1998-04-03 2002-06-18 Symyx Technologies, Inc. Rapid characterization of polymers
US6855258B2 (en) * 1999-04-02 2005-02-15 Symyx Technologies, Inc. Methods for characterization of polymers using multi-dimensional liquid chromatography with parallel second-dimension sampling
US6190550B1 (en) * 1999-09-30 2001-02-20 Cohesive Technologies, Inc. Monitoring high performance liquid chromatography
US6460420B1 (en) * 2000-04-13 2002-10-08 Sandia National Laboratories Flowmeter for pressure-driven chromatography systems
US6635173B2 (en) * 2000-12-28 2003-10-21 Cohesive Technologies, Inc. Multi column chromatography system
US6528167B2 (en) 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
WO2003021251A1 (en) * 2001-08-28 2003-03-13 Symyx Technologies, Inc. Methods for characterization of polymers using multi-dimentional liquid chromatography
EP1440304A2 (en) * 2001-11-02 2004-07-28 Millipore Corporation Membrane adsorber device
EP1518115A2 (en) * 2002-06-10 2005-03-30 Phynexus, Inc. Biomolecule open channel solid phase extraction systems and methods
FI20020592A (en) * 2002-03-27 2003-09-28 Danisco Sweeteners Oy Method for separating sugars, sugar alcohols, carbohydrates and mixtures thereof from solutions containing them
US20040241721A1 (en) * 2003-05-08 2004-12-02 Gjerde Douglas T. Open channel solid phase extraction systems and methods
US7151167B2 (en) * 2002-06-10 2006-12-19 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7879621B2 (en) * 2003-05-08 2011-02-01 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7122640B2 (en) * 2002-06-10 2006-10-17 Phynexus, Inc. Open channel solid phase extraction systems and methods
EP1565261A1 (en) * 2002-11-25 2005-08-24 Varian, Inc. Irregularly-shaped macroporous copolymer particles and methods of using same
WO2004047947A1 (en) * 2002-11-26 2004-06-10 Prime Separations Incorporated Chromatographic separation process
US6962658B2 (en) * 2003-05-20 2005-11-08 Eksigent Technologies, Llc Variable flow rate injector
US6977143B1 (en) * 2003-09-08 2005-12-20 Quest Diagnostics Investments Incorporated Determination of testosterone by mass spectrometry
US7309426B2 (en) * 2004-04-23 2007-12-18 Agilent Technologies, Inc. Composition and method for high efficiency chromatography
US20060169640A1 (en) * 2005-02-01 2006-08-03 Hubert Quinn High throughput screening, purification and recovery system for large and small molecules
US7972867B2 (en) 2005-04-06 2011-07-05 Quest Diagnostics Investments Incorporated Methods for detecting vitamin D metabolites by mass spectrometry
US7745226B2 (en) 2005-04-06 2010-06-29 Quest Diagnostics Investments Incorporated Methods for detecting vitamin D metabolites
US20070196833A1 (en) * 2005-04-21 2007-08-23 Gjerde Douglas T Open channel solid phase extraction systems and methods
US7935921B2 (en) * 2006-05-26 2011-05-03 Laboratory Corporation Of America Holdings Methods and systems for the quantitative analysis of biomarkers
US8017015B2 (en) * 2006-10-20 2011-09-13 Quest Diagnostics Investments Incorporated Monolithic column chromatography
US20080181932A1 (en) * 2007-01-30 2008-07-31 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
WO2008112388A1 (en) 2007-03-14 2008-09-18 Drugtech Corporation Spatial arrangement of particles in a drinking device for oral delivery of pharmaceuticals
WO2008150488A1 (en) * 2007-06-01 2008-12-11 Laboratory Corporation Of America Holdings Methods and systems for quantification of peptides and other analytes
US8017403B2 (en) 2007-06-14 2011-09-13 Quest Diagnostics Investments Incorporated Mass spectrometry method for measuring vitamin B6 in body fluid
US7767463B2 (en) * 2007-06-15 2010-08-03 Cohesive Technologies, Inc. Method for screening mobile phases in chromatography systems
US20090134325A1 (en) 2007-11-27 2009-05-28 Goldman Mildred M Methods for detecting estradiol by mass spectrometry
US7972868B2 (en) 2007-11-28 2011-07-05 Quest Diagnostics Investments Incorporated Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry
US8916385B2 (en) * 2007-12-13 2014-12-23 Quest Diagnostics Investments, Inc. Methods for detecting estrone by mass spectrometry
WO2009091680A1 (en) * 2008-01-15 2009-07-23 Merck & Co., Inc. High performance liquid chromatographic (hplc) purification of proteins using semi-compressible resins
TW200933195A (en) * 2008-01-28 2009-08-01 Ind Tech Res Inst Autostereoscopic display
US7834313B2 (en) 2008-08-08 2010-11-16 Quest Diagnostics Investments Incorporated Mass spectrometry assay for plasma-renin
US7893399B2 (en) * 2008-09-09 2011-02-22 Quest Diagnostics Investments Incorporated Methods for detecting dehydroepiandrosterone by mass spectrometry
US7952067B2 (en) 2008-10-06 2011-05-31 Quest Diagnostics Investments Incorporated Methods for detecting vitamin C by mass spectrometry
US7804063B2 (en) * 2008-10-06 2010-09-28 Quest Diagnostics Investments Incorporated Methods for detecting dihydrotestosterone by mass spectrometry
US8039794B2 (en) * 2008-12-16 2011-10-18 Quest Diagnostics Investments Incorporated Mass spectrometry assay for thiopurine-S-methyl transferase activity and products generated thereby
US7952068B2 (en) 2008-12-16 2011-05-31 Quest Diagnostics Investments Incorporated Methods for detecting catecholamines by mass spectrometry
US8399829B2 (en) 2008-12-18 2013-03-19 Quest Diagnostics Investments Incorporated Vitamin B2 detection by mass spectrometry
WO2010075175A1 (en) * 2008-12-23 2010-07-01 Quest Diagnostics Investments Incorporated Mass spectrometry assay for estrogenic compounds
US8153962B2 (en) 2008-12-24 2012-04-10 Quest Diagnostics Investments Incorporated Mass spectrometry assay for congenital adrenal hyperplasia
CN105067698B (en) 2009-11-05 2018-11-20 奎斯特诊断投资公司 Quantify insulin like growth factor-1 and Insulin-like growth factor-II with high resolution mass spec method
US8034627B2 (en) 2009-12-03 2011-10-11 Quest Diagnostics Investments Incorporated Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry
US7977117B2 (en) * 2009-12-03 2011-07-12 Quest Diagnostics Investments Incorprated Vitamin D metabolite determination utilizing mass spectrometry following derivatization
CA2783797A1 (en) 2009-12-11 2011-06-16 Quest Diagnostics Investments Incorporated Mass spectrometric determination of non-derivatized, non-metabolized vitamin d
US9034653B2 (en) 2009-12-11 2015-05-19 Quest Diagnostics Investments Inc. Mass spectrometry of steroidal compounds in multiplexed patient samples
WO2011084751A1 (en) 2009-12-21 2011-07-14 Quest Diagnostics Investments Incorporated Glucagon detection and quantitation by mass spectrometry
WO2011127044A2 (en) * 2010-04-05 2011-10-13 Purdue Research Foundation Method of packing chromatographic columns
US10215765B2 (en) 2010-09-15 2019-02-26 Quest Diagnostics Investments Incorporated Detection of vitamins A and E by tandem mass spectrometry
US8557593B2 (en) 2010-09-16 2013-10-15 Quest Diagnostics Investments Incorporated Mass spectrometric determination of eicosapentaenoic acid and docosahexaenoic acid
JP6049621B2 (en) 2010-09-26 2016-12-21 ダ・ユー・エンタープライジズ、エルエルシー Analyte separation
WO2012058516A1 (en) 2010-10-29 2012-05-03 Thermo Finnigan Llc Method and system for liquid chromatograph with compressibility and viscosity monitoring to identify fluids
CN107085118A (en) 2010-10-29 2017-08-22 恩姆菲舍尔科技公司 Automated systems and methods for sample preparation and analysis
US20130206653A1 (en) * 2010-10-29 2013-08-15 John E. Brann Modular Multiple-Column Chromatography Cartridge
EP2633325B1 (en) 2010-10-29 2016-12-28 Cohesive Technologies Inc. Lc-ms separation and detection of vitamin d metabolites
EP3570036A1 (en) 2010-10-29 2019-11-20 Cohesive Technologies Inc. Lc-ms configuration for purification and detection of analytes having a broad range of hydrophobicities
US9012835B2 (en) 2010-11-08 2015-04-21 Georgetown University Methods for simultaneous quantification of thyroid hormones and metabolites thereof by mass spectrometry
CN107064330A (en) 2010-12-28 2017-08-18 探索诊断投资公司 Pass through mass spectrography quantitative insulin
US9177766B2 (en) 2010-12-30 2015-11-03 Quest Diagnostics Investments Incorporated Mass spectrometric quantitation assay for metabolites of leflunomide
US8728824B2 (en) 2011-06-22 2014-05-20 Quest Diagnostics Investments Inc. Mass spectrometric determination of fatty acids
EP2783388A4 (en) 2011-11-23 2015-12-09 Quest Diagnostics Invest Inc Kisspeptin-54 detection by tandem mass spectrometry
US8669519B2 (en) 2011-12-05 2014-03-11 Quest Diagnostics Investments, Inc. Methods for detecting reverse triiodothyronine by mass spectrometry
US8779355B2 (en) 2011-12-28 2014-07-15 Quest Diagnostics Investments, Inc. Methods for detecting lacosamide by mass spectrometry
AU2014268417A1 (en) 2013-05-23 2015-11-26 Iphenotype Llc Methods and systems for assisting persons, product providers and/or service providers
EP2680005A1 (en) 2012-06-28 2014-01-01 Rheinische Friedrich-Wilhelms-Universität Bonn Lipid analysis
US9404900B2 (en) 2012-12-21 2016-08-02 Thermo Finnigan Llc System for analysis of phase-I and phase-II metabolites and parent compounds without hydrolysis
US9594074B2 (en) 2012-12-26 2017-03-14 Quest Diagnostics Investments Incorporated C peptide detection by mass spectrometry
US20160061787A1 (en) * 2013-04-08 2016-03-03 The General Hospital Corporation Automated analysis systems
WO2015011522A1 (en) 2013-07-23 2015-01-29 Tubitak Ume Multi-task sample preparation system with reconfigurable modules for on-line dilution, enzymatic digestion and fractionation
US10324082B2 (en) 2015-03-03 2019-06-18 Quest Diagnostics Investments Llc Methods for quantitation of insulin levels by mass spectrometry
US20190257801A1 (en) * 2016-06-21 2019-08-22 Purdue Research Foundation Uniformly dense stationary phase for chromatography
WO2019217899A2 (en) 2018-05-11 2019-11-14 Laboratory Corporation Of America Holdings Compositions and methods to detect kidney fibrosis
US20190369113A1 (en) 2018-06-01 2019-12-05 Laboratory Corporation Of America Holdings Simplified Biosample Processing for LC-MS/MS

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208284A (en) * 1965-05-11 1980-06-17 Hahn Hans H Apparatus for distribution separation processes
GB1148661A (en) * 1965-05-11 1969-04-16 Victor Pretorius Improvements relating to chromatography
GB1452896A (en) * 1972-12-21 1976-10-20 Nat Res Dev Packing materials
SE434312B (en) * 1975-10-22 1984-07-16 Atomic Energy Authority Uk Porosgel, speaking for the front up and tell the priority over the same for the front tell up of a ceramic catalyst materials
US4512897A (en) * 1981-07-28 1985-04-23 Amf Incorporated Molecular separation column and use thereof
SE464816B (en) * 1985-10-15 1991-06-17 Nilsson Kjell Makroporoesa particles foerfarande foer its framstaellning and its anvaendning
JPH0669521B2 (en) * 1986-12-23 1994-09-07 三菱化成エンジニアリング株式会社 Chromatographic separation method
US5019270A (en) * 1989-07-06 1991-05-28 Perseptive Biosystems, Inc. Perfusive chromatography
US5228989A (en) * 1989-07-06 1993-07-20 Perseptive Biosystems, Inc. Perfusive chromatography
US5164090A (en) * 1989-11-06 1992-11-17 E. R. Squibb & Sons, Inc. Process for the direct chromatographic analysis of drugs and metabolites in whole blood samples using internal surface reverse phase technology
US5328603A (en) * 1990-03-20 1994-07-12 The Center For Innovative Technology Lignocellulosic and cellulosic beads for use in affinity and immunoaffinity chromatography of high molecular weight proteins
DE4018778A1 (en) * 1990-06-12 1991-12-19 Braun Melsungen Ag Adsorption material for the selective removal of ldl and / and vldl
CA2132965A1 (en) * 1992-03-27 1993-10-14 Noubar B. Afeyan Rapid hypersensitive flowthrough immunodetection system
US5256298A (en) * 1992-04-22 1993-10-26 Powell Paul E Continuous-belt separator/reactor and method
US5268097A (en) * 1992-06-19 1993-12-07 Sepracor Inc. Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same
US5387347A (en) * 1993-09-15 1995-02-07 Rothchild; Ronald D. Method and apparatus for continuous chromatographic separation
US5503933A (en) * 1994-02-25 1996-04-02 Purdue Research Foundation Covalently bonded coatings

Also Published As

Publication number Publication date
TW518246B (en) 2003-01-21
DE69601722D1 (en) 1999-04-15
EP0838032A2 (en) 1998-04-29
AU706707B2 (en) 1999-06-24
AU7599596A (en) 1997-05-22
CA2236712C (en) 2003-09-16
WO1997016724A3 (en) 1997-06-05
WO1997016724A2 (en) 1997-05-09
JP3354155B2 (en) 2002-12-09
US5919368A (en) 1999-07-06
US5772874A (en) 1998-06-30
PL326484A1 (en) 1998-09-28
DK0838032T3 (en) 1999-09-27
JPH11514743A (en) 1999-12-14
DE69601722T2 (en) 1999-07-29
DK838032T3 (en)
CA2236712A1 (en) 1997-05-09
ES2130857T3 (en) 1999-07-01
EP0838032B1 (en) 1999-03-10
NZ322280A (en) 1999-08-30

Similar Documents

Publication Publication Date Title
DE69607321D1 (en) Cleaning method and composition
DE69613861T2 (en) Reverse turnmimetika and coherent procedures
DE69606025D1 (en) chemical apparatus
DE69502662D1 (en) Ionenfallenmassenspektromer and operating method for this
DE69702929T2 (en) Light-emitting device and display device
AT209334T (en) Scanning device and method
DE69605630D1 (en) self-powered device
DE69412901D1 (en) Ubungsgerät and methods
NO970914D0 (en) Formasjonsisolerings- and test device and method
DE69131274D1 (en) Flow immunosensor method and device
DE69612942D1 (en) Holding device and its installation method
DE69615735D1 (en) Process cartridge and image forming apparatus
DE69115571D1 (en) Zelleinkapselungsverfahren and apparatus
DE69501880T2 (en) surgical device
DE69609175T2 (en) instrument endodontic and procedural
DE69223243D1 (en) Navigation apparatus and navigation method
DE69427279D1 (en) Aufzeichungsgerät and imaging method for imaging parameters
DE69124571D1 (en) Emulsification and apparatus
DE69614436D1 (en) Process cartridge and image forming apparatus
DE69417879D1 (en) Dehydrogenierungsverfahren and geraet here for
DE69509786T2 (en) Rückspülluftfilteranordnung and procedural
DE69507019D1 (en) Saliva testing method and device
DE69616805D1 (en) Intraoral device
DE69121091D1 (en) Road and built-recycling method and apparatus
DE69408405T2 (en) Plasma CVD method and apparatus

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee